FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5105, 617 aa 1>>>pF1KB5105 617 - 617 aa - 617 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8016+/- 0.001; mu= 16.4593+/- 0.060 mean_var=69.0589+/-13.673, 0's: 0 Z-trim(104.1): 18 B-trim: 0 in 0/49 Lambda= 0.154335 statistics sampled from 7730 (7738) to 7730 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.609), E-opt: 0.2 (0.238), width: 16 Scan time: 3.470 The best scores are: opt bits E(32554) CCDS2976.1 ATP6V1A gene_id:523|Hs108|chr3 ( 617) 4060 913.5 0 CCDS8924.1 ATP5B gene_id:506|Hs108|chr12 ( 529) 337 84.5 3.9e-16 CCDS6014.1 ATP6V1B2 gene_id:526|Hs108|chr8 ( 511) 305 77.4 5.3e-14 CCDS1912.1 ATP6V1B1 gene_id:525|Hs108|chr2 ( 513) 289 73.8 6.3e-13 >>CCDS2976.1 ATP6V1A gene_id:523|Hs108|chr3 (617 aa) initn: 4060 init1: 4060 opt: 4060 Z-score: 4882.1 bits: 913.5 E(32554): 0 Smith-Waterman score: 4060; 100.0% identity (100.0% similar) in 617 aa overlap (1-617:1-617) 10 20 30 40 50 60 pF1KB5 MDFSKLPKILDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 MDFSKLPKILDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 MATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GVNVSALSRDIKWDFTPCKNLRVGSHITGGDIYGIVSENSLIKHKIMLPPRNRGTVTYIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 GVNVSALSRDIKWDFTPCKNLRVGSHITGGDIYGIVSENSLIKHKIMLPPRNRGTVTYIA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PPGNYDTSDVVLELEFEGVKEKFTMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 PPGNYDTSDVVLELEFEGVKEKFTMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 VQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 KVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALRE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 ISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 ISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 VTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTEFVPLRTKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 VTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTEFVPLRTKAK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 EILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 EILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 LSNMIAFYDMARRAVETTAQSDNKITWSIIREHMGDILYKLSSMKFKDPLKDGEAKIKSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 LSNMIAFYDMARRAVETTAQSDNKITWSIIREHMGDILYKLSSMKFKDPLKDGEAKIKSD 550 560 570 580 590 600 610 pF1KB5 YAQLLEDMQNAFRSLED ::::::::::::::::: CCDS29 YAQLLEDMQNAFRSLED 610 >>CCDS8924.1 ATP5B gene_id:506|Hs108|chr12 (529 aa) initn: 147 init1: 147 opt: 337 Z-score: 403.1 bits: 84.5 E(32554): 3.9e-16 Smith-Waterman score: 395; 26.4% identity (59.4% similar) in 394 aa overlap (141-522:97-466) 120 130 140 150 160 pF1KB5 SQTQSIYIPRGVNVSALSRDIKWDFTPCKNLRVGSHITGGDIYGIVSENS--LIKHKIML :.:..:. . . :. ... :.. . .: CCDS89 IGAVVDVQFDEGLPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVL 70 80 90 100 110 120 170 180 190 200 210 220 pF1KB5 PPRNRGTVTYIAPPGNYDTSDVVLELEFEGVKEK--FTMVQVWPVRQVRPVTEKLPANHP . :. : : . .: .... : . :. . : :.. : .. ... CCDS89 ---DSGAPIKI--PVGPETLGRIMNVIGEPIDERGPIKTKQFAPIHAEAPEFMEMSVEQE 130 140 150 160 170 180 230 240 250 260 270 280 pF1KB5 LL-TGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKY---SNSDVIIYVGCGERGN .: :: .:.: : : ..:: .. :. : ::::. . : . ... ...: ::: CCDS89 ILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTR 190 200 210 220 230 240 290 300 310 320 330 340 pF1KB5 EMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDM-G : ... ... : . .. : . ...::: . : : .:: ::.:..:::::. : CCDS89 EGNDLYHEMIE-SGVINLK--DATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEG 250 260 270 280 290 350 360 370 380 390 400 pF1KB5 YHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPERE : .. :. :...: :.:. :...:. :: :.. .... :: .: . CCDS89 QDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTK-------K 300 310 320 330 340 350 410 420 430 440 450 pF1KB5 GSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMR-- ::.. : :. :. :..::. ..:.. ... :.. .:. .:.:. : : :. : CCDS89 GSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPN 360 370 380 390 400 410 460 470 480 490 500 510 pF1KB5 -ALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDD . .:.:: . ...:::. ..: .:. ..: :.: ::.:. :. :. CCDS89 IVGSEHYD--------VARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQR- 420 430 440 450 460 520 530 540 550 560 570 pF1KB5 FLQQNGYTPYDRFCPFYKTVGMLSNMIAFYDMARRAVETTAQSDNKITWSIIREHMGDIL ::.: CCDS89 FLSQPFQVAEVFTGHMGKLVPLKETIKGFQQILAGEYDHLPEQAFYMVGPIEEAVAKADK 470 480 490 500 510 520 >>CCDS6014.1 ATP6V1B2 gene_id:526|Hs108|chr8 (511 aa) initn: 206 init1: 155 opt: 305 Z-score: 364.9 bits: 77.4 E(32554): 5.3e-14 Smith-Waterman score: 306; 24.3% identity (55.6% similar) in 374 aa overlap (201-558:148-499) 180 190 200 210 220 pF1KB5 RNRGTVTYIAPPGNYDTSDVVLELEFEGVKEKFTMVQVWPVR-QVRPVTEKLPANHPLLT : : .. :. : : :.. . : CCDS60 ILRTPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEM-----IQT 120 130 140 150 160 170 230 240 250 260 270 pF1KB5 GQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYS-----NSDVIIY------VGCG : ..:.. ..: : .: : .. :. .. . . ..::. : . . CCDS60 GISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVVDYSEENFAIVFA 180 190 200 210 220 230 280 290 300 310 320 330 pF1KB5 ERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEYF- : .: :. : : . .: .:..... : : .: :. : . ..: .:.. CCDS60 AMGVNM-ETAR-FFKSDFEENGSMDNV----CLFLNLANDPTIERIITPRLALTTAEFLA 240 250 260 270 280 340 350 360 370 380 390 pF1KB5 RDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGN . :: .. . : .::::::.:. :.:. :.:.:. . ::..:::::::. : CCDS60 YQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVE--G- 290 300 310 320 330 340 400 410 420 430 440 450 pF1KB5 PEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKY :.::.. . .. :. :.. :. . : :.. .:..: .:. .: .: : : :. CCDS60 --RNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRL 350 360 370 380 390 400 460 470 480 490 500 510 pF1KB5 MR-ALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIK :. :. : . .. . . . .. .:. . .::. .:. : . :: . .. CCDS60 MKSAIGEGMTRK--DHADVSNQLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFE 410 420 430 440 450 520 530 540 550 560 570 pF1KB5 DDFLQQNGYTPYDRFCPFYKTVGMLSNMIAFY--DMARRAVETTAQSDNKITWSIIREHM .:. :. ::. : .:. . ... .. .: .: ..: CCDS60 RNFIAQG---PYENRTVF-ETLDIGWQLLRIFPKEMLKRIPQSTLSEFYPRDSAKH 460 470 480 490 500 510 580 590 600 610 pF1KB5 GDILYKLSSMKFKDPLKDGEAKIKSDYAQLLEDMQNAFRSLED >>CCDS1912.1 ATP6V1B1 gene_id:525|Hs108|chr2 (513 aa) initn: 155 init1: 155 opt: 289 Z-score: 345.6 bits: 73.8 E(32554): 6.3e-13 Smith-Waterman score: 289; 27.3% identity (58.8% similar) in 238 aa overlap (299-531:241-468) 270 280 290 300 310 320 pF1KB5 SDVIIYVGCGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIY : . .. : . : : .: :. : . CCDS19 KAVLDYHDDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPR 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB5 TGITLSEYF-RDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYE ..: .:.. . :: .. . : .::::::.:. :.:. :.:.:. . ::..:: CCDS19 LALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYE 280 290 300 310 320 330 390 400 410 420 430 440 pF1KB5 RAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIV---QVFWGLDKKLAQRKH :::::. : : ::.. . .. :. :.. :. . : :.. :.. .:..: .:. CCDS19 RAGRVE--G---RGGSITQIPILTMPNDDITHPIPDLT-GFITEGQIY--VDRQLHNRQI 340 350 360 370 380 450 460 470 480 490 500 pF1KB5 FPSVNWLISYSKYMR-ALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAE .: .: : : :. :. :. : . .. . . .. .:. . .::. .:. CCDS19 YPPINVLPSLSRLMKSAIGEGMTRK--DHGDVSNQLYACYAIGKDVQAMKAVVGEEALTS 390 400 410 420 430 440 510 520 530 540 550 560 pF1KB5 TDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMIAFYDMARRAVETTAQSDN : . :: . .. .:..:. : . : CCDS19 EDLLYLEFLQKFEKNFINQGPYENRSVFESLDLGWKLLRIFPKEMLKRIPQAVIDEFYSR 450 460 470 480 490 500 617 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:15:42 2016 done: Sat Nov 5 07:15:42 2016 Total Scan time: 3.470 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]