Result of FASTA (omim) for
pF1KB5108
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5108, 795 aa
1>>>pF1KB5108 795 - 795 aa - 795 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1862+/-0.000508; mu= 10.7344+/- 0.031
mean_var=130.9368+/-27.753, 0's: 0 Z-trim(111.4): 323 B-trim: 1122 in 2/49
Lambda= 0.112084
statistics sampled from 19614 (20008) to 19614 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.582), E-opt: 0.2 (0.235), width: 16
Scan time: 12.420
The best scores are: opt bits E(85289)
NP_001026859 (OMIM: 603873) phospholipase A-2-acti ( 795) 5350 877.8 0
XP_011516374 (OMIM: 603873) PREDICTED: phospholipa ( 524) 3422 565.9 1.5e-160
NP_001308475 (OMIM: 603873) phospholipase A-2-acti ( 772) 3373 558.1 5.1e-158
XP_016870808 (OMIM: 603873) PREDICTED: phospholipa ( 534) 3269 541.2 4.4e-153
XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD re ( 540) 326 65.3 8e-10
NP_001013433 (OMIM: 606278) F-box/WD repeat-contai ( 589) 326 65.3 8.6e-10
NP_060785 (OMIM: 606278) F-box/WD repeat-containin ( 627) 326 65.3 9.1e-10
XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 326 65.4 9.7e-10
XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 326 65.4 9.7e-10
XP_011530385 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 326 65.4 1e-09
XP_011530387 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 326 65.4 1e-09
XP_011530386 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 326 65.4 1e-09
NP_361014 (OMIM: 606278) F-box/WD repeat-containin ( 707) 326 65.4 1e-09
XP_016863851 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 326 65.4 1e-09
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 304 61.6 6.4e-09
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 304 61.6 6.4e-09
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 304 61.6 6.4e-09
XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655) 294 60.2 3.4e-08
XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655) 294 60.2 3.4e-08
NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655) 294 60.2 3.4e-08
XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658) 294 60.2 3.4e-08
XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672) 294 60.2 3.5e-08
XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672) 294 60.2 3.5e-08
XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672) 294 60.2 3.5e-08
XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675) 294 60.2 3.5e-08
XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675) 294 60.2 3.5e-08
XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675) 294 60.2 3.5e-08
XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675) 294 60.2 3.5e-08
XP_016880191 (OMIM: 601545,607432) PREDICTED: plat ( 345) 286 58.7 5e-08
NP_000421 (OMIM: 601545,607432) platelet-activatin ( 410) 286 58.8 5.7e-08
XP_016880189 (OMIM: 601545,607432) PREDICTED: plat ( 410) 286 58.8 5.7e-08
XP_016880188 (OMIM: 601545,607432) PREDICTED: plat ( 410) 286 58.8 5.7e-08
XP_016880190 (OMIM: 601545,607432) PREDICTED: plat ( 410) 286 58.8 5.7e-08
NP_006089 (OMIM: 176981) receptor of activated pro ( 317) 284 58.4 5.8e-08
XP_011522203 (OMIM: 601545,607432) PREDICTED: plat ( 428) 286 58.8 5.9e-08
XP_011522204 (OMIM: 601545,607432) PREDICTED: plat ( 428) 286 58.8 5.9e-08
XP_011522205 (OMIM: 601545,607432) PREDICTED: plat ( 428) 286 58.8 5.9e-08
NP_001188493 (OMIM: 605961) pleiotropic regulator ( 505) 286 58.8 6.7e-08
NP_002660 (OMIM: 605961) pleiotropic regulator 1 i ( 514) 286 58.8 6.8e-08
XP_011510137 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 276 57.1 1.4e-07
XP_016860389 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 276 57.1 1.4e-07
XP_016860391 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 276 57.1 1.4e-07
XP_016860390 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 276 57.1 1.4e-07
XP_016860387 (OMIM: 612173) PREDICTED: sperm-assoc ( 390) 276 57.1 1.7e-07
XP_016860386 (OMIM: 612173) PREDICTED: sperm-assoc ( 512) 276 57.2 2.1e-07
XP_016860385 (OMIM: 612173) PREDICTED: sperm-assoc ( 512) 276 57.2 2.1e-07
XP_011510125 (OMIM: 612173) PREDICTED: sperm-assoc ( 528) 276 57.2 2.1e-07
XP_011510124 (OMIM: 612173) PREDICTED: sperm-assoc ( 528) 276 57.2 2.1e-07
XP_011510123 (OMIM: 612173) PREDICTED: sperm-assoc ( 537) 276 57.2 2.2e-07
XP_011510120 (OMIM: 612173) PREDICTED: sperm-assoc ( 577) 276 57.2 2.3e-07
>>NP_001026859 (OMIM: 603873) phospholipase A-2-activati (795 aa)
initn: 5350 init1: 5350 opt: 5350 Z-score: 4685.4 bits: 877.8 E(85289): 0
Smith-Waterman score: 5350; 100.0% identity (100.0% similar) in 795 aa overlap (1-795:1-795)
10 20 30 40 50 60
pF1KB5 MTSGATRYRLSCSLRGHELDVRGLVCCAYPPGAFVSVSRDRTTRLWAPDSPNRSFTEMHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSGATRYRLSCSLRGHELDVRGLVCCAYPPGAFVSVSRDRTTRLWAPDSPNRSFTEMHC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 MSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKNTVCSLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKNTVCSLSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTVKLWKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTVKLWKA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 GRCERTFSGHEDCVRGLAILSETEFLSCANDASIRRWQITGECLEVYYGHTNYIYSISVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRCERTFSGHEDCVRGLAILSETEFLSCANDASIRRWQITGECLEVYYGHTNYIYSISVF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PNCRDFVTTAEDRSLRIWKHGECAQTIRLPAQSIWCCCVLDNGDIVVGASDGIIRVFTES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNCRDFVTTAEDRSLRIWKHGECAQTIRLPAQSIWCCCVLDNGDIVVGASDGIIRVFTES
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 EDRTASAEEIKAFEKELSHATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDRTASAEEIKAFEKELSHATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 KVEAYQWSVSEGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVEAYQWSVSEGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 NTSDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTKGQMLGLGNPSFSDPFTGGGRYVPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTSDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTKGQMLGLGNPSFSDPFTGGGRYVPG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 SSGSSNTLPTADPFTGAGRYVPGSASMGTTMAGVDPFTGNSAYRSAASKTMNIYFPKKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSGSSNTLPTADPFTGAGRYVPGSASMGTTMAGVDPFTGNSAYRSAASKTMNIYFPKKEA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 VTFDQANPTQILGKLKELNGTAPEEKKLTEDDLILLEKILSLICNSSSEKPTVQQLQILW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTFDQANPTQILGKLKELNGTAPEEKKLTEDDLILLEKILSLICNSSSEKPTVQQLQILW
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 KAINCPEDIVFPALDILRLSIKHPSVNENFCNEKEGAQFSSHLINLLNPKGKPANQLLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAINCPEDIVFPALDILRLSIKHPSVNENFCNEKEGAQFSSHLINLLNPKGKPANQLLAL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 RTFCNCFVGQAGQKLMMSQRESLMSHAIELKSGSNKNIHIALATLALNYSVCFHKDHNIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTFCNCFVGQAGQKLMMSQRESLMSHAIELKSGSNKNIHIALATLALNYSVCFHKDHNIE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 GKAQCLSLISTILEVVQDLEATFRLLVALGTLISDDSNAVQLAKSLGVDSQIKKYSSVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKAQCLSLISTILEVVQDLEATFRLLVALGTLISDDSNAVQLAKSLGVDSQIKKYSSVSE
730 740 750 760 770 780
790
pF1KB5 PAKVSECCRFILNLL
:::::::::::::::
NP_001 PAKVSECCRFILNLL
790
>>XP_011516374 (OMIM: 603873) PREDICTED: phospholipase A (524 aa)
initn: 3533 init1: 3416 opt: 3422 Z-score: 3003.1 bits: 565.9 E(85289): 1.5e-160
Smith-Waterman score: 3422; 96.5% identity (97.7% similar) in 519 aa overlap (1-518:1-518)
10 20 30 40 50 60
pF1KB5 MTSGATRYRLSCSLRGHELDVRGLVCCAYPPGAFVSVSRDRTTRLWAPDSPNRSFTEMHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTSGATRYRLSCSLRGHELDVRGLVCCAYPPGAFVSVSRDRTTRLWAPDSPNRSFTEMHC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 MSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKNTVCSLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKNTVCSLSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTVKLWKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTVKLWKA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 GRCERTFSGHEDCVRGLAILSETEFLSCANDASIRRWQITGECLEVYYGHTNYIYSISVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRCERTFSGHEDCVRGLAILSETEFLSCANDASIRRWQITGECLEVYYGHTNYIYSISVF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PNCRDFVTTAEDRSLRIWKHGECAQTIRLPAQSIWCCCVLDNGDIVVGASDGIIRVFTES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNCRDFVTTAEDRSLRIWKHGECAQTIRLPAQSIWCCCVLDNGDIVVGASDGIIRVFTES
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 EDRTASAEEIKAFEKELSHATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDRTASAEEIKAFEKELSHATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 KVEAYQWSVSEGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVEAYQWSVSEGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 NTSDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTKGQMLGLGNPSFSDPFTGGGRYVPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTSDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTKGQMLGLGNPSFSDPFTGGGRYVPG
430 440 450 460 470 480
490 500 510 520 530
pF1KB5 SSGSSNTLPTADPFTGA-GRYVPGSASMGTTMAGVDPFTGNSAYRSAASKTMNIYFPKKE
::::::::::::::: : . : ::.. . . :.:
XP_011 SSGSSNTLPTADPFTDNRGTHQP-RHSMSAITGEMLPITSREGAM
490 500 510 520
540 550 560 570 580 590
pF1KB5 AVTFDQANPTQILGKLKELNGTAPEEKKLTEDDLILLEKILSLICNSSSEKPTVQQLQIL
>>NP_001308475 (OMIM: 603873) phospholipase A-2-activati (772 aa)
initn: 3365 init1: 3365 opt: 3373 Z-score: 2957.9 bits: 558.1 E(85289): 5.1e-158
Smith-Waterman score: 5136; 97.1% identity (97.1% similar) in 795 aa overlap (1-795:1-772)
10 20 30 40 50 60
pF1KB5 MTSGATRYRLSCSLRGHELDVRGLVCCAYPPGAFVSVSRDRTTRLWAPDSPNRSFTEMHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSGATRYRLSCSLRGHELDVRGLVCCAYPPGAFVSVSRDRTTRLWAPDSPNRSFTEMHC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 MSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKNTVCSLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKNTVCSLSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTVKLWKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTVKLWKA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 GRCERTFSGHEDCVRGLAILSETEFLSCANDASIRRWQITGECLEVYYGHTNYIYSISVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRCERTFSGHEDCVRGLAILSETEFLSCANDASIRRWQITGECLEVYYGHTNYIYSISVF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PNCRDFVTTAEDRSLRIWKHGECAQTIRLPAQSIWCCCVLDNGDIVVGASDGIIRVFTES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNCRDFVTTAEDRSLRIWKHGECAQTIRLPAQSIWCCCVLDNGDIVVGASDGIIRVFTES
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 EDRTASAEEIKAFEKELSHATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDRTASAEEIKAFEKELSHATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 KVEAYQWSVSEGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVEAYQWSVSEGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 NTSDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTKGQMLGLGNPSFSDPFTGGGRYVPG
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTSDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTKGQMLGLGNPSFSDPFTG-------
430 440 450 460 470
490 500 510 520 530 540
pF1KB5 SSGSSNTLPTADPFTGAGRYVPGSASMGTTMAGVDPFTGNSAYRSAASKTMNIYFPKKEA
::::::::::::::::::::::::::::::::::::::::::::
NP_001 ----------------AGRYVPGSASMGTTMAGVDPFTGNSAYRSAASKTMNIYFPKKEA
480 490 500 510
550 560 570 580 590 600
pF1KB5 VTFDQANPTQILGKLKELNGTAPEEKKLTEDDLILLEKILSLICNSSSEKPTVQQLQILW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTFDQANPTQILGKLKELNGTAPEEKKLTEDDLILLEKILSLICNSSSEKPTVQQLQILW
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB5 KAINCPEDIVFPALDILRLSIKHPSVNENFCNEKEGAQFSSHLINLLNPKGKPANQLLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAINCPEDIVFPALDILRLSIKHPSVNENFCNEKEGAQFSSHLINLLNPKGKPANQLLAL
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB5 RTFCNCFVGQAGQKLMMSQRESLMSHAIELKSGSNKNIHIALATLALNYSVCFHKDHNIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTFCNCFVGQAGQKLMMSQRESLMSHAIELKSGSNKNIHIALATLALNYSVCFHKDHNIE
640 650 660 670 680 690
730 740 750 760 770 780
pF1KB5 GKAQCLSLISTILEVVQDLEATFRLLVALGTLISDDSNAVQLAKSLGVDSQIKKYSSVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKAQCLSLISTILEVVQDLEATFRLLVALGTLISDDSNAVQLAKSLGVDSQIKKYSSVSE
700 710 720 730 740 750
790
pF1KB5 PAKVSECCRFILNLL
:::::::::::::::
NP_001 PAKVSECCRFILNLL
760 770
>>XP_016870808 (OMIM: 603873) PREDICTED: phospholipase A (534 aa)
initn: 3269 init1: 3269 opt: 3269 Z-score: 2869.3 bits: 541.2 E(85289): 4.4e-153
Smith-Waterman score: 3269; 99.4% identity (100.0% similar) in 476 aa overlap (1-476:1-476)
10 20 30 40 50 60
pF1KB5 MTSGATRYRLSCSLRGHELDVRGLVCCAYPPGAFVSVSRDRTTRLWAPDSPNRSFTEMHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTSGATRYRLSCSLRGHELDVRGLVCCAYPPGAFVSVSRDRTTRLWAPDSPNRSFTEMHC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 MSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKNTVCSLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKNTVCSLSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTVKLWKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTVKLWKA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 GRCERTFSGHEDCVRGLAILSETEFLSCANDASIRRWQITGECLEVYYGHTNYIYSISVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRCERTFSGHEDCVRGLAILSETEFLSCANDASIRRWQITGECLEVYYGHTNYIYSISVF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PNCRDFVTTAEDRSLRIWKHGECAQTIRLPAQSIWCCCVLDNGDIVVGASDGIIRVFTES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNCRDFVTTAEDRSLRIWKHGECAQTIRLPAQSIWCCCVLDNGDIVVGASDGIIRVFTES
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 EDRTASAEEIKAFEKELSHATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDRTASAEEIKAFEKELSHATIDSKTGDLGDINAEQLPGREHLNEPGTREGQTRLIRDGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 KVEAYQWSVSEGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVEAYQWSVSEGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 NTSDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTKGQMLGLGNPSFSDPFTGGGRYVPG
:::::::::::::::::::::::::::::::::::::::::::::::::::::...
XP_016 NTSDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTKGQMLGLGNPSFSDPFTGSSKTSIV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 SSGSSNTLPTADPFTGAGRYVPGSASMGTTMAGVDPFTGNSAYRSAASKTMNIYFPKKEA
XP_016 LFEKFRTLVHFCLFFILHAQVVVGMFRALRDLLTHYPQQILLQIIGEPTNQDTA
490 500 510 520 530
>>XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD repeat (540 aa)
initn: 272 init1: 126 opt: 326 Z-score: 297.3 bits: 65.3 E(85289): 8e-10
Smith-Waterman score: 353; 25.8% identity (63.1% similar) in 260 aa overlap (13-262:249-488)
10 20 30 40
pF1KB5 MTSGATRYRLSCSLRGHELDVRGLVCCAYPPGAFVSVSRDRT
.: :: . :. . . ..: : :::
XP_011 CLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGH---TGGVWSSQMRDNIIISGSTDRT
220 230 240 250 260 270
50 60 70 80 90 100
pF1KB5 TRLWAPDSPNRSFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSP
..: .. . .: . ::.. : :. . . ...:. : .. ......
XP_011 LKVWNAETGE----CIHTLYGHTSTVRCMHLHEKR-------VVSGSRDATLRVWDIETG
280 290 300 310 320
110 120 130 140 150
pF1KB5 MPLYILKGHKNTV-CSLSSGKFGTLLSGSWDTTAKVW--LNDKCMMTLQGHTAAVWAVKI
. :..: :: .: : .:. ..::..: .::: .. :. :::::: :.....
XP_011 QCLHVLMGHVAAVRCVQYDGR--RVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF
330 340 350 360 370 380
160 170 180 190 200 210
pF1KB5 LPEQGL-MLTGSADKTVKLW--KAGRCERTFSGHEDCVRGLAILSETEFLSCANDASIRR
.:. ...:: : ....: ..: : .:..::.. . :. :... ..: :....
XP_011 ---DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGME-LKDNILVSGNADSTVKI
390 400 410 420 430
220 230 240 250 260 270
pF1KB5 WQI-TGECLEVYYGHTNYIYSISVFPNCRDFV-TTAEDRSLRIW--KHGECAQTIRLPAQ
:.: ::.::.. : ... ... . ..:: :...: ....: : ::
XP_011 WDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLES
440 450 460 470 480 490
280 290 300 310 320 330
pF1KB5 SIWCCCVLDNGDIVVGASDGIIRVFTESEDRTASAEEIKAFEKELSHATIDSKTGDLGDI
XP_011 GGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
500 510 520 530 540
>>NP_001013433 (OMIM: 606278) F-box/WD repeat-containing (589 aa)
initn: 272 init1: 126 opt: 326 Z-score: 296.8 bits: 65.3 E(85289): 8.6e-10
Smith-Waterman score: 353; 25.8% identity (63.1% similar) in 260 aa overlap (13-262:298-537)
10 20 30 40
pF1KB5 MTSGATRYRLSCSLRGHELDVRGLVCCAYPPGAFVSVSRDRT
.: :: . :. . . ..: : :::
NP_001 CLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGH---TGGVWSSQMRDNIIISGSTDRT
270 280 290 300 310 320
50 60 70 80 90 100
pF1KB5 TRLWAPDSPNRSFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSP
..: .. . .: . ::.. : :. . . ...:. : .. ......
NP_001 LKVWNAETGE----CIHTLYGHTSTVRCMHLHEKR-------VVSGSRDATLRVWDIETG
330 340 350 360 370
110 120 130 140 150
pF1KB5 MPLYILKGHKNTV-CSLSSGKFGTLLSGSWDTTAKVW--LNDKCMMTLQGHTAAVWAVKI
. :..: :: .: : .:. ..::..: .::: .. :. :::::: :.....
NP_001 QCLHVLMGHVAAVRCVQYDGR--RVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF
380 390 400 410 420 430
160 170 180 190 200 210
pF1KB5 LPEQGL-MLTGSADKTVKLW--KAGRCERTFSGHEDCVRGLAILSETEFLSCANDASIRR
.:. ...:: : ....: ..: : .:..::.. . :. :... ..: :....
NP_001 ---DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGME-LKDNILVSGNADSTVKI
440 450 460 470 480
220 230 240 250 260 270
pF1KB5 WQI-TGECLEVYYGHTNYIYSISVFPNCRDFV-TTAEDRSLRIW--KHGECAQTIRLPAQ
:.: ::.::.. : ... ... . ..:: :...: ....: : ::
NP_001 WDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLES
490 500 510 520 530 540
280 290 300 310 320 330
pF1KB5 SIWCCCVLDNGDIVVGASDGIIRVFTESEDRTASAEEIKAFEKELSHATIDSKTGDLGDI
NP_001 GGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
550 560 570 580
>>NP_060785 (OMIM: 606278) F-box/WD repeat-containing pr (627 aa)
initn: 272 init1: 126 opt: 326 Z-score: 296.4 bits: 65.3 E(85289): 9.1e-10
Smith-Waterman score: 353; 25.8% identity (63.1% similar) in 260 aa overlap (13-262:336-575)
10 20 30 40
pF1KB5 MTSGATRYRLSCSLRGHELDVRGLVCCAYPPGAFVSVSRDRT
.: :: . :. . . ..: : :::
NP_060 CLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGH---TGGVWSSQMRDNIIISGSTDRT
310 320 330 340 350 360
50 60 70 80 90 100
pF1KB5 TRLWAPDSPNRSFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSP
..: .. . .: . ::.. : :. . . ...:. : .. ......
NP_060 LKVWNAETGE----CIHTLYGHTSTVRCMHLHEKR-------VVSGSRDATLRVWDIETG
370 380 390 400 410
110 120 130 140 150
pF1KB5 MPLYILKGHKNTV-CSLSSGKFGTLLSGSWDTTAKVW--LNDKCMMTLQGHTAAVWAVKI
. :..: :: .: : .:. ..::..: .::: .. :. :::::: :.....
NP_060 QCLHVLMGHVAAVRCVQYDGR--RVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF
420 430 440 450 460
160 170 180 190 200 210
pF1KB5 LPEQGL-MLTGSADKTVKLW--KAGRCERTFSGHEDCVRGLAILSETEFLSCANDASIRR
.:. ...:: : ....: ..: : .:..::.. . :. :... ..: :....
NP_060 ---DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGME-LKDNILVSGNADSTVKI
470 480 490 500 510 520
220 230 240 250 260 270
pF1KB5 WQI-TGECLEVYYGHTNYIYSISVFPNCRDFV-TTAEDRSLRIW--KHGECAQTIRLPAQ
:.: ::.::.. : ... ... . ..:: :...: ....: : ::
NP_060 WDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLES
530 540 550 560 570 580
280 290 300 310 320 330
pF1KB5 SIWCCCVLDNGDIVVGASDGIIRVFTESEDRTASAEEIKAFEKELSHATIDSKTGDLGDI
NP_060 GGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
590 600 610 620
>>XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD repeat (679 aa)
initn: 272 init1: 126 opt: 326 Z-score: 295.9 bits: 65.4 E(85289): 9.7e-10
Smith-Waterman score: 353; 25.8% identity (63.1% similar) in 260 aa overlap (13-262:388-627)
10 20 30 40
pF1KB5 MTSGATRYRLSCSLRGHELDVRGLVCCAYPPGAFVSVSRDRT
.: :: . :. . . ..: : :::
XP_011 CLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGH---TGGVWSSQMRDNIIISGSTDRT
360 370 380 390 400 410
50 60 70 80 90 100
pF1KB5 TRLWAPDSPNRSFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSP
..: .. . .: . ::.. : :. . . ...:. : .. ......
XP_011 LKVWNAETGE----CIHTLYGHTSTVRCMHLHEKR-------VVSGSRDATLRVWDIETG
420 430 440 450 460
110 120 130 140 150
pF1KB5 MPLYILKGHKNTV-CSLSSGKFGTLLSGSWDTTAKVW--LNDKCMMTLQGHTAAVWAVKI
. :..: :: .: : .:. ..::..: .::: .. :. :::::: :.....
XP_011 QCLHVLMGHVAAVRCVQYDGR--RVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF
470 480 490 500 510 520
160 170 180 190 200 210
pF1KB5 LPEQGL-MLTGSADKTVKLW--KAGRCERTFSGHEDCVRGLAILSETEFLSCANDASIRR
.:. ...:: : ....: ..: : .:..::.. . :. :... ..: :....
XP_011 ---DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGME-LKDNILVSGNADSTVKI
530 540 550 560 570
220 230 240 250 260 270
pF1KB5 WQI-TGECLEVYYGHTNYIYSISVFPNCRDFV-TTAEDRSLRIW--KHGECAQTIRLPAQ
:.: ::.::.. : ... ... . ..:: :...: ....: : ::
XP_011 WDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLES
580 590 600 610 620 630
280 290 300 310 320 330
pF1KB5 SIWCCCVLDNGDIVVGASDGIIRVFTESEDRTASAEEIKAFEKELSHATIDSKTGDLGDI
XP_011 GGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
640 650 660 670
>>XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD repeat (679 aa)
initn: 272 init1: 126 opt: 326 Z-score: 295.9 bits: 65.4 E(85289): 9.7e-10
Smith-Waterman score: 353; 25.8% identity (63.1% similar) in 260 aa overlap (13-262:388-627)
10 20 30 40
pF1KB5 MTSGATRYRLSCSLRGHELDVRGLVCCAYPPGAFVSVSRDRT
.: :: . :. . . ..: : :::
XP_011 CLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGH---TGGVWSSQMRDNIIISGSTDRT
360 370 380 390 400 410
50 60 70 80 90 100
pF1KB5 TRLWAPDSPNRSFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSP
..: .. . .: . ::.. : :. . . ...:. : .. ......
XP_011 LKVWNAETGE----CIHTLYGHTSTVRCMHLHEKR-------VVSGSRDATLRVWDIETG
420 430 440 450 460
110 120 130 140 150
pF1KB5 MPLYILKGHKNTV-CSLSSGKFGTLLSGSWDTTAKVW--LNDKCMMTLQGHTAAVWAVKI
. :..: :: .: : .:. ..::..: .::: .. :. :::::: :.....
XP_011 QCLHVLMGHVAAVRCVQYDGR--RVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF
470 480 490 500 510 520
160 170 180 190 200 210
pF1KB5 LPEQGL-MLTGSADKTVKLW--KAGRCERTFSGHEDCVRGLAILSETEFLSCANDASIRR
.:. ...:: : ....: ..: : .:..::.. . :. :... ..: :....
XP_011 ---DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGME-LKDNILVSGNADSTVKI
530 540 550 560 570
220 230 240 250 260 270
pF1KB5 WQI-TGECLEVYYGHTNYIYSISVFPNCRDFV-TTAEDRSLRIW--KHGECAQTIRLPAQ
:.: ::.::.. : ... ... . ..:: :...: ....: : ::
XP_011 WDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLES
580 590 600 610 620 630
280 290 300 310 320 330
pF1KB5 SIWCCCVLDNGDIVVGASDGIIRVFTESEDRTASAEEIKAFEKELSHATIDSKTGDLGDI
XP_011 GGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
640 650 660 670
>>XP_011530385 (OMIM: 606278) PREDICTED: F-box/WD repeat (707 aa)
initn: 272 init1: 126 opt: 326 Z-score: 295.6 bits: 65.4 E(85289): 1e-09
Smith-Waterman score: 353; 25.8% identity (63.1% similar) in 260 aa overlap (13-262:416-655)
10 20 30 40
pF1KB5 MTSGATRYRLSCSLRGHELDVRGLVCCAYPPGAFVSVSRDRT
.: :: . :. . . ..: : :::
XP_011 CLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGH---TGGVWSSQMRDNIIISGSTDRT
390 400 410 420 430 440
50 60 70 80 90 100
pF1KB5 TRLWAPDSPNRSFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSP
..: .. . .: . ::.. : :. . . ...:. : .. ......
XP_011 LKVWNAETGE----CIHTLYGHTSTVRCMHLHEKR-------VVSGSRDATLRVWDIETG
450 460 470 480 490
110 120 130 140 150
pF1KB5 MPLYILKGHKNTV-CSLSSGKFGTLLSGSWDTTAKVW--LNDKCMMTLQGHTAAVWAVKI
. :..: :: .: : .:. ..::..: .::: .. :. :::::: :.....
XP_011 QCLHVLMGHVAAVRCVQYDGR--RVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF
500 510 520 530 540
160 170 180 190 200 210
pF1KB5 LPEQGL-MLTGSADKTVKLW--KAGRCERTFSGHEDCVRGLAILSETEFLSCANDASIRR
.:. ...:: : ....: ..: : .:..::.. . :. :... ..: :....
XP_011 ---DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGME-LKDNILVSGNADSTVKI
550 560 570 580 590 600
220 230 240 250 260 270
pF1KB5 WQI-TGECLEVYYGHTNYIYSISVFPNCRDFV-TTAEDRSLRIW--KHGECAQTIRLPAQ
:.: ::.::.. : ... ... . ..:: :...: ....: : ::
XP_011 WDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLES
610 620 630 640 650 660
280 290 300 310 320 330
pF1KB5 SIWCCCVLDNGDIVVGASDGIIRVFTESEDRTASAEEIKAFEKELSHATIDSKTGDLGDI
XP_011 GGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
670 680 690 700
795 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 16:05:34 2016 done: Thu Nov 3 16:05:36 2016
Total Scan time: 12.420 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]