Result of FASTA (omim) for
pF1KB5109
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5109, 606 aa
1>>>pF1KB5109 606 - 606 aa - 606 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9429+/-0.000633; mu= 10.4898+/- 0.039
mean_var=169.6130+/-38.642, 0's: 0 Z-trim(109.2): 292 B-trim: 78 in 1/47
Lambda= 0.098479
statistics sampled from 17011 (17363) to 17011 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.547), E-opt: 0.2 (0.204), width: 16
Scan time: 9.480
The best scores are: opt bits E(85289)
NP_059830 (OMIM: 604734) WD repeat-containing prot ( 606) 4113 598.2 2.7e-170
NP_005103 (OMIM: 604734) WD repeat-containing prot ( 466) 2863 420.4 6.5e-117
XP_016864369 (OMIM: 604734) PREDICTED: WD repeat-c ( 659) 2678 394.3 6.8e-109
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 335 61.1 6.8e-09
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 335 61.1 6.8e-09
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 335 61.1 6.8e-09
NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359) 295 55.5 3.7e-07
NP_056241 (OMIM: 614783,614813) POC1 centriolar pr ( 407) 295 55.5 4e-07
NP_001290176 (OMIM: 609540) WD repeat-containing p ( 305) 282 53.6 1.2e-06
XP_011520396 (OMIM: 609540) PREDICTED: WD repeat-c ( 305) 282 53.6 1.2e-06
NP_079510 (OMIM: 609540) WD repeat-containing prot ( 305) 282 53.6 1.2e-06
XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 ( 300) 279 53.1 1.6e-06
XP_011531863 (OMIM: 614783,614813) PREDICTED: POC1 ( 326) 277 52.9 2e-06
XP_011531862 (OMIM: 614783,614813) PREDICTED: POC1 ( 374) 277 52.9 2.2e-06
NP_004757 (OMIM: 606990) coatomer subunit beta' [H ( 906) 278 53.5 3.7e-06
XP_016861593 (OMIM: 614783,614813) PREDICTED: POC1 ( 321) 259 50.3 1.2e-05
NP_001155053 (OMIM: 614783,614813) POC1 centriolar ( 369) 259 50.4 1.3e-05
NP_001290177 (OMIM: 609540) WD repeat-containing p ( 212) 253 49.3 1.6e-05
XP_011531865 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 245 48.2 3.9e-05
XP_011531867 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 245 48.2 3.9e-05
XP_011531866 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 245 48.2 3.9e-05
NP_002066 (OMIM: 139130,145500,617024) guanine nuc ( 340) 244 48.2 5.4e-05
NP_004805 (OMIM: 607797) U5 small nuclear ribonucl ( 357) 242 47.9 6.8e-05
XP_016863001 (OMIM: 606990) PREDICTED: coatomer su ( 877) 243 48.5 0.00011
NP_001284500 (OMIM: 139130,145500,617024) guanine ( 339) 235 46.9 0.00013
NP_001231855 (OMIM: 607795,615922) U4/U6 small nuc ( 521) 231 46.6 0.00026
NP_004688 (OMIM: 607795,615922) U4/U6 small nuclea ( 522) 231 46.6 0.00026
XP_011525181 (OMIM: 614767) PREDICTED: striatin-4 ( 365) 228 46.0 0.00027
XP_016882207 (OMIM: 614767) PREDICTED: striatin-4 ( 539) 228 46.1 0.00036
NP_001309195 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 223 45.1 0.00037
NP_001309196 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 223 45.1 0.00037
XP_006723237 (OMIM: 614767) PREDICTED: striatin-4 ( 641) 228 46.2 0.0004
XP_016882206 (OMIM: 614767) PREDICTED: striatin-4 ( 641) 228 46.2 0.0004
XP_016882205 (OMIM: 614767) PREDICTED: striatin-4 ( 656) 228 46.2 0.00041
XP_011541982 (OMIM: 616194) PREDICTED: U3 small nu ( 518) 226 45.8 0.00042
NP_115551 (OMIM: 616194) U3 small nucleolar RNA-as ( 518) 226 45.8 0.00042
NP_037535 (OMIM: 614767) striatin-4 isoform 1 [Hom ( 753) 228 46.3 0.00045
NP_001034966 (OMIM: 614767) striatin-4 isoform 2 [ ( 760) 228 46.3 0.00045
XP_006723235 (OMIM: 614767) PREDICTED: striatin-4 ( 768) 228 46.3 0.00046
XP_006723234 (OMIM: 614767) PREDICTED: striatin-4 ( 775) 228 46.3 0.00046
XP_011519255 (OMIM: 139130,145500,617024) PREDICTE ( 360) 221 45.0 0.00054
XP_005267076 (OMIM: 215100,266500,601757,614879) P ( 285) 214 43.9 0.00092
NP_000279 (OMIM: 215100,266500,601757,614879) pero ( 323) 214 43.9 0.001
NP_001271359 (OMIM: 616194) U3 small nucleolar RNA ( 499) 216 44.4 0.0011
NP_006444 (OMIM: 605915) transducin beta-like prot ( 808) 218 44.9 0.0013
XP_016860391 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 205 42.6 0.0024
XP_016860390 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 205 42.6 0.0024
XP_011510137 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 205 42.6 0.0024
XP_016860389 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 205 42.6 0.0024
XP_016860387 (OMIM: 612173) PREDICTED: sperm-assoc ( 390) 205 42.7 0.0028
>>NP_059830 (OMIM: 604734) WD repeat-containing protein (606 aa)
initn: 4113 init1: 4113 opt: 4113 Z-score: 3178.3 bits: 598.2 E(85289): 2.7e-170
Smith-Waterman score: 4113; 99.8% identity (100.0% similar) in 606 aa overlap (1-606:1-606)
10 20 30 40 50 60
pF1KB5 MPYEIKKVFASLPQVERGVSKIIGGDPKGNNFLYTNGKCVILRNIDNPALADIYTEHAHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 MPYEIKKVFASLPQVERGVSKIIGGDPKGNNFLYTNGKCVILRNIDNPALADIYTEHAHQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 VVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GEGREKFGAVFLWDSGSSVGEITGHNKVINSVDIKQSRPYRLATGSDDNCAAFFEGPPFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 GEGREKFGAVFLWDSGSSVGEITGHNKVINSVDIKQSRPYRLATGSDDNCAAFFEGPPFK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 FKFTVGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCALGGSKAHDGGIYAI
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 FKFTIGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCALGGSKAHDGGIYAI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 SWSPDSTHLLSASGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLWQKDHLLSVSLSGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 SWSPDSTHLLSASGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLWQKDHLLSVSLSGY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 INYLDRNNPSKPLHVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYWDSETGENDSFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 INYLDRNNPSKPLHVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYWDSETGENDSFA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 GKGHTNQVSRMTVDESGQLISCSMDDTVRYTSLMLRDYSGQGVVKLDVQPKCVAVGPGGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 GKGHTNQVSRMTVDESGQLISCSMDDTVRYTSLMLRDYSGQGVVKLDVQPKCVAVGPGGY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 AVVVCIGQIVLLKDQRKCFSIDNPGYEPEVVAVHPGGDTVAIGGVDGNVRLYSILGTTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 AVVVCIGQIVLLKDQRKCFSIDNPGYEPEVVAVHPGGDTVAIGGVDGNVRLYSILGTTLK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 DEGKLLEAKGPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 DEGKLLEAKGPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAW
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 SPDNEHFASGGMDMMVYVWTLSDPETRVKIQDAHRLHHVSSLAWLDEHTLVTTSHDASVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 SPDNEHFASGGMDMMVYVWTLSDPETRVKIQDAHRLHHVSSLAWLDEHTLVTTSHDASVK
550 560 570 580 590 600
pF1KB5 EWTITY
::::::
NP_059 EWTITY
>>NP_005103 (OMIM: 604734) WD repeat-containing protein (466 aa)
initn: 2863 init1: 2863 opt: 2863 Z-score: 2219.9 bits: 420.4 E(85289): 6.5e-117
Smith-Waterman score: 2879; 76.9% identity (76.9% similar) in 606 aa overlap (1-606:1-466)
10 20 30 40 50 60
pF1KB5 MPYEIKKVFASLPQVERGVSKIIGGDPKGNNFLYTNGKCVILRNIDNPALADIYTEHAHQ
::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MPYEIKKVFASLPQVERGVSKIIGGDPKGNNFLYTNGKCVILRNID--------------
10 20 30 40
70 80 90 100 110 120
pF1KB5 VVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVV
NP_005 ------------------------------------------------------------
130 140 150 160 170 180
pF1KB5 GEGREKFGAVFLWDSGSSVGEITGHNKVINSVDIKQSRPYRLATGSDDNCAAFFEGPPFK
NP_005 ------------------------------------------------------------
190 200 210 220 230 240
pF1KB5 FKFTVGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCALGGSKAHDGGIYAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ------DHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCALGGSKAHDGGIYAI
50 60 70 80 90 100
250 260 270 280 290 300
pF1KB5 SWSPDSTHLLSASGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLWQKDHLLSVSLSGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SWSPDSTHLLSASGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLWQKDHLLSVSLSGY
110 120 130 140 150 160
310 320 330 340 350 360
pF1KB5 INYLDRNNPSKPLHVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYWDSETGENDSFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 INYLDRNNPSKPLHVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYWDSETGENDSFA
170 180 190 200 210 220
370 380 390 400 410 420
pF1KB5 GKGHTNQVSRMTVDESGQLISCSMDDTVRYTSLMLRDYSGQGVVKLDVQPKCVAVGPGGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GKGHTNQVSRMTVDESGQLISCSMDDTVRYTSLMLRDYSGQGVVKLDVQPKCVAVGPGGY
230 240 250 260 270 280
430 440 450 460 470 480
pF1KB5 AVVVCIGQIVLLKDQRKCFSIDNPGYEPEVVAVHPGGDTVAIGGVDGNVRLYSILGTTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AVVVCIGQIVLLKDQRKCFSIDNPGYEPEVVAVHPGGDTVAIGGVDGNVRLYSILGTTLK
290 300 310 320 330 340
490 500 510 520 530 540
pF1KB5 DEGKLLEAKGPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DEGKLLEAKGPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAW
350 360 370 380 390 400
550 560 570 580 590 600
pF1KB5 SPDNEHFASGGMDMMVYVWTLSDPETRVKIQDAHRLHHVSSLAWLDEHTLVTTSHDASVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SPDNEHFASGGMDMMVYVWTLSDPETRVKIQDAHRLHHVSSLAWLDEHTLVTTSHDASVK
410 420 430 440 450 460
pF1KB5 EWTITY
::::::
NP_005 EWTITY
>>XP_016864369 (OMIM: 604734) PREDICTED: WD repeat-conta (659 aa)
initn: 2678 init1: 2678 opt: 2678 Z-score: 2076.0 bits: 394.3 E(85289): 6.8e-109
Smith-Waterman score: 3862; 91.5% identity (91.7% similar) in 638 aa overlap (22-606:22-659)
10 20 30 40 50 60
pF1KB5 MPYEIKKVFASLPQVERGVSKIIGGDPKGNNFLYTNGKCVILRNIDNPALADIYTEHAHQ
:::::::::::::::::::::::::::::::::::::::
XP_016 MPYEIKKVFASLPQVERGVSKIIGGDPKGNNFLYTNGKCVILRNIDNPALADIYTEHAHQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GEGREKFGAVFLWDSGSSVGEITGHNKVINSVDIKQSRPYRLATGSDDNCAAFFEGPPFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEGREKFGAVFLWDSGSSVGEITGHNKVINSVDIKQSRPYRLATGSDDNCAAFFEGPPFK
130 140 150 160 170 180
190 200 210
pF1KB5 FKFTVGDHSRFVNCVRFSPDGNRFATASADGQ----------------------------
::::.:::::::::::::::::::::::::::
XP_016 FKFTIGDHSRFVNCVRFSPDGNRFATASADGQTRRQSPVNACLLLNHTGSLVCEPRFSTA
190 200 210 220 230 240
220 230 240
pF1KB5 -------------------------IYIYDGKTGEKVCALGGSKAHDGGIYAISWSPDST
:::::::::::::::::::::::::::::::::::
XP_016 TVHGETAYSRGCSHTHDPHVFISWKIYIYDGKTGEKVCALGGSKAHDGGIYAISWSPDST
250 260 270 280 290 300
250 260 270 280 290 300
pF1KB5 HLLSASGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLWQKDHLLSVSLSGYINYLDRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLLSASGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLWQKDHLLSVSLSGYINYLDRN
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB5 NPSKPLHVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYWDSETGENDSFAGKGHTNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPSKPLHVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYWDSETGENDSFAGKGHTNQ
370 380 390 400 410 420
370 380 390 400 410 420
pF1KB5 VSRMTVDESGQLISCSMDDTVRYTSLMLRDYSGQGVVKLDVQPKCVAVGPGGYAVVVCIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSRMTVDESGQLISCSMDDTVRYTSLMLRDYSGQGVVKLDVQPKCVAVGPGGYAVVVCIG
430 440 450 460 470 480
430 440 450 460 470 480
pF1KB5 QIVLLKDQRKCFSIDNPGYEPEVVAVHPGGDTVAIGGVDGNVRLYSILGTTLKDEGKLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIVLLKDQRKCFSIDNPGYEPEVVAVHPGGDTVAIGGVDGNVRLYSILGTTLKDEGKLLE
490 500 510 520 530 540
490 500 510 520 530 540
pF1KB5 AKGPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKGPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHF
550 560 570 580 590 600
550 560 570 580 590 600
pF1KB5 ASGGMDMMVYVWTLSDPETRVKIQDAHRLHHVSSLAWLDEHTLVTTSHDASVKEWTITY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASGGMDMMVYVWTLSDPETRVKIQDAHRLHHVSSLAWLDEHTLVTTSHDASVKEWTITY
610 620 630 640 650
>>XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-conta (334 aa)
initn: 288 init1: 127 opt: 335 Z-score: 280.6 bits: 61.1 E(85289): 6.8e-09
Smith-Waterman score: 335; 29.6% identity (58.2% similar) in 311 aa overlap (177-472:33-330)
150 160 170 180 190 200
pF1KB5 KVINSVDIKQSRPYRLATGSDDNCAAFFEGPPFKFKFTVGDHSRFVNCVRFSPDGNRFAT
: . .:::.. :.. :. :.:::.:. .:.
XP_005 TEEKKPETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLAS
10 20 30 40 50 60
210 220 230 240 250 260
pF1KB5 ASADGQIYI---YDGKTGEKVCALGGSKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDV
.::: : : :::: :: ...: : :: ..:: ::. :.::: ::: :::::
XP_005 SSADKLIKIWGAYDGKF-EK--TISG---HKLGISDVAWSSDSNLLVSASDDKTLKIWDV
70 80 90 100 110
270 280 290 300 310 320
pF1KB5 SVNSVVSTFPMGSTVLDQQLGCLW--QKDHLLSVSLSGYINYLDRNNPSKPLHVIKGHSK
: .. ..:. :. . . : . :.. ..: :.. . : .. .: :... .::
XP_005 SSGKCLKTLKGHSNYV---FCCNFNPQSNLIVSGSFDESVRIWDVKT-GKCLKTLPAHSD
120 130 140 150 160 170
330 340 350 360 370 380
pF1KB5 SIQCLTVHKNGGKSYIYSGSHDGHINYWDSETGENDSFAGKGHTNQVSRMTVDESGQLI-
.. .:: : : : :.:.:: ::. .:. . . :: . . .:. :
XP_005 PVS--AVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYIL
180 190 200 210 220 230
390 400 410 420 430
pF1KB5 SCSMDDTVR---YTS-LMLRDYSGQGVVKLDVQPKCVAVGPGGYAVVVCIGQIVLLKD-Q
. ..:.:.. :.. :. :.:. : . . ..: : . : ..: . . :
XP_005 AATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTG-GKWIVSGSEDNLVYIWNLQ
240 250 260 270 280
440 450 460 470 480 490
pF1KB5 RKCFSIDNPGYEPEVV--AVHPGGDTVAIGGV--DGNVRLYSILGTTLKDEGKLLEAKGP
: . :. :. : :: . .: ... : ...:.
XP_005 TKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC
290 300 310 320 330
500 510 520 530 540 550
pF1KB5 VTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGG
>>NP_060058 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 288 init1: 127 opt: 335 Z-score: 280.6 bits: 61.1 E(85289): 6.8e-09
Smith-Waterman score: 335; 29.6% identity (58.2% similar) in 311 aa overlap (177-472:33-330)
150 160 170 180 190 200
pF1KB5 KVINSVDIKQSRPYRLATGSDDNCAAFFEGPPFKFKFTVGDHSRFVNCVRFSPDGNRFAT
: . .:::.. :.. :. :.:::.:. .:.
NP_060 TEEKKPETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLAS
10 20 30 40 50 60
210 220 230 240 250 260
pF1KB5 ASADGQIYI---YDGKTGEKVCALGGSKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDV
.::: : : :::: :: ...: : :: ..:: ::. :.::: ::: :::::
NP_060 SSADKLIKIWGAYDGKF-EK--TISG---HKLGISDVAWSSDSNLLVSASDDKTLKIWDV
70 80 90 100 110
270 280 290 300 310 320
pF1KB5 SVNSVVSTFPMGSTVLDQQLGCLW--QKDHLLSVSLSGYINYLDRNNPSKPLHVIKGHSK
: .. ..:. :. . . : . :.. ..: :.. . : .. .: :... .::
NP_060 SSGKCLKTLKGHSNYV---FCCNFNPQSNLIVSGSFDESVRIWDVKT-GKCLKTLPAHSD
120 130 140 150 160 170
330 340 350 360 370 380
pF1KB5 SIQCLTVHKNGGKSYIYSGSHDGHINYWDSETGENDSFAGKGHTNQVSRMTVDESGQLI-
.. .:: : : : :.:.:: ::. .:. . . :: . . .:. :
NP_060 PVS--AVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYIL
180 190 200 210 220 230
390 400 410 420 430
pF1KB5 SCSMDDTVR---YTS-LMLRDYSGQGVVKLDVQPKCVAVGPGGYAVVVCIGQIVLLKD-Q
. ..:.:.. :.. :. :.:. : . . ..: : . : ..: . . :
NP_060 AATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTG-GKWIVSGSEDNLVYIWNLQ
240 250 260 270 280
440 450 460 470 480 490
pF1KB5 RKCFSIDNPGYEPEVV--AVHPGGDTVAIGGV--DGNVRLYSILGTTLKDEGKLLEAKGP
: . :. :. : :: . .: ... : ...:.
NP_060 TKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC
290 300 310 320 330
500 510 520 530 540 550
pF1KB5 VTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGG
>>NP_438172 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 288 init1: 127 opt: 335 Z-score: 280.6 bits: 61.1 E(85289): 6.8e-09
Smith-Waterman score: 335; 29.6% identity (58.2% similar) in 311 aa overlap (177-472:33-330)
150 160 170 180 190 200
pF1KB5 KVINSVDIKQSRPYRLATGSDDNCAAFFEGPPFKFKFTVGDHSRFVNCVRFSPDGNRFAT
: . .:::.. :.. :. :.:::.:. .:.
NP_438 TEEKKPETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLAS
10 20 30 40 50 60
210 220 230 240 250 260
pF1KB5 ASADGQIYI---YDGKTGEKVCALGGSKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDV
.::: : : :::: :: ...: : :: ..:: ::. :.::: ::: :::::
NP_438 SSADKLIKIWGAYDGKF-EK--TISG---HKLGISDVAWSSDSNLLVSASDDKTLKIWDV
70 80 90 100 110
270 280 290 300 310 320
pF1KB5 SVNSVVSTFPMGSTVLDQQLGCLW--QKDHLLSVSLSGYINYLDRNNPSKPLHVIKGHSK
: .. ..:. :. . . : . :.. ..: :.. . : .. .: :... .::
NP_438 SSGKCLKTLKGHSNYV---FCCNFNPQSNLIVSGSFDESVRIWDVKT-GKCLKTLPAHSD
120 130 140 150 160 170
330 340 350 360 370 380
pF1KB5 SIQCLTVHKNGGKSYIYSGSHDGHINYWDSETGENDSFAGKGHTNQVSRMTVDESGQLI-
.. .:: : : : :.:.:: ::. .:. . . :: . . .:. :
NP_438 PVS--AVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYIL
180 190 200 210 220 230
390 400 410 420 430
pF1KB5 SCSMDDTVR---YTS-LMLRDYSGQGVVKLDVQPKCVAVGPGGYAVVVCIGQIVLLKD-Q
. ..:.:.. :.. :. :.:. : . . ..: : . : ..: . . :
NP_438 AATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTG-GKWIVSGSEDNLVYIWNLQ
240 250 260 270 280
440 450 460 470 480 490
pF1KB5 RKCFSIDNPGYEPEVV--AVHPGGDTVAIGGV--DGNVRLYSILGTTLKDEGKLLEAKGP
: . :. :. : :: . .: ... : ...:.
NP_438 TKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC
290 300 310 320 330
500 510 520 530 540 550
pF1KB5 VTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGG
>>NP_001155052 (OMIM: 614783,614813) POC1 centriolar pro (359 aa)
initn: 385 init1: 125 opt: 295 Z-score: 249.5 bits: 55.5 E(85289): 3.7e-07
Smith-Waterman score: 299; 22.9% identity (59.5% similar) in 328 aa overlap (46-370:7-315)
20 30 40 50 60 70
pF1KB5 ERGVSKIIGGDPKGNNFLYTNGKCVILRNIDNPALADIYTEHAHQVVVAKYAPSGFYIAS
..:.: . : :. . .. . .::
NP_001 MAAPCAEDPSLERHFKGHRDAVTCVDFSINTKQLAS
10 20 30
80 90 100 110 120 130
pF1KB5 GDVSGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVVGEGREKFGAVFLWDS
:.... : .: .: . :.. . . .. ... .: . .:.: .: .:
NP_001 GSMDSCLMVWH--MKPQSRAYRFTGHKDAVTCVNFSPSGHLLA--SGSRDK--TVRIWVP
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB5 GSSVGEIT---GHNKVINSVDIKQSRPYRLATGSDDNCAAFFEGPPFKFKFTVGDHSRFV
. . :: : .:. .. :: . : ..:.:::. . . :: :....: .:
NP_001 NVK-GESTVFRAHTATVRSVHFC-SDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWV
100 110 120 130 140
200 210 220 230 240 250
pF1KB5 NCVRFSPDGNRFATASADGQIYIYDGKTGEKVCALGGSKAHDGGIYAISWSPDSTHLLSA
:..::::: ...:: : . ..: .. : :. . . : : . ... :..: . .:
NP_001 RCAKFSPDGRLIVSASDDKTVKLWDKSSRE--CVHSYCE-HGGFVTYVDFHPSGTCIAAA
150 160 170 180 190 200
260 270 280 290 300 310
pF1KB5 SGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLWQKDHLLSVSLSGYINYLDRNNPSKP
. :.: :.::: .. ... . . :.... :. . ..:...: .. .. :: . ..
NP_001 GMDNTVKVWDVRTHRLLQHYQLHSAAVNG-LSFHPSGNYLITASSDSTLKILDLME-GRL
210 220 230 240 250 260
320 330 340 350 360 370
pF1KB5 LHVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYWDSETGENDSFAGKGHTNQVSRMT
:....::. .. ..: :. ::. : .. : : : ... .:....: :
NP_001 LYTLHGHQGPATTVAFSRTG--EYFASGGSDEQVMVWKS----NFDIVDHGEVTKVPRPP
270 280 290 300 310
380 390 400 410 420 430
pF1KB5 VDESGQLISCSMDDTVRYTSLMLRDYSGQGVVKLDVQPKCVAVGPGGYAVVVCIGQIVLL
NP_001 ATLASSMGNLTVSILEQRLTLTEDKLKQCLENQQLIMQRATP
320 330 340 350
>>NP_056241 (OMIM: 614783,614813) POC1 centriolar protei (407 aa)
initn: 385 init1: 125 opt: 295 Z-score: 248.8 bits: 55.5 E(85289): 4e-07
Smith-Waterman score: 299; 22.9% identity (59.5% similar) in 328 aa overlap (46-370:7-315)
20 30 40 50 60 70
pF1KB5 ERGVSKIIGGDPKGNNFLYTNGKCVILRNIDNPALADIYTEHAHQVVVAKYAPSGFYIAS
..:.: . : :. . .. . .::
NP_056 MAAPCAEDPSLERHFKGHRDAVTCVDFSINTKQLAS
10 20 30
80 90 100 110 120 130
pF1KB5 GDVSGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVVGEGREKFGAVFLWDS
:.... : .: .: . :.. . . .. ... .: . .:.: .: .:
NP_056 GSMDSCLMVWH--MKPQSRAYRFTGHKDAVTCVNFSPSGHLLA--SGSRDK--TVRIWVP
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB5 GSSVGEIT---GHNKVINSVDIKQSRPYRLATGSDDNCAAFFEGPPFKFKFTVGDHSRFV
. . :: : .:. .. :: . : ..:.:::. . . :: :....: .:
NP_056 NVK-GESTVFRAHTATVRSVHFC-SDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWV
100 110 120 130 140
200 210 220 230 240 250
pF1KB5 NCVRFSPDGNRFATASADGQIYIYDGKTGEKVCALGGSKAHDGGIYAISWSPDSTHLLSA
:..::::: ...:: : . ..: .. : :. . . : : . ... :..: . .:
NP_056 RCAKFSPDGRLIVSASDDKTVKLWDKSSRE--CVHSYCE-HGGFVTYVDFHPSGTCIAAA
150 160 170 180 190 200
260 270 280 290 300 310
pF1KB5 SGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLWQKDHLLSVSLSGYINYLDRNNPSKP
. :.: :.::: .. ... . . :.... :. . ..:...: .. .. :: . ..
NP_056 GMDNTVKVWDVRTHRLLQHYQLHSAAVNG-LSFHPSGNYLITASSDSTLKILDLME-GRL
210 220 230 240 250 260
320 330 340 350 360 370
pF1KB5 LHVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYWDSETGENDSFAGKGHTNQVSRMT
:....::. .. ..: :. ::. : .. : : : ... .:....: :
NP_056 LYTLHGHQGPATTVAFSRTG--EYFASGGSDEQVMVWKS----NFDIVDHGEVTKVPRPP
270 280 290 300 310
380 390 400 410 420 430
pF1KB5 VDESGQLISCSMDDTVRYTSLMLRDYSGQGVVKLDVQPKCVAVGPGGYAVVVCIGQIVLL
NP_056 ATLASSMGNLPEVDFPVPPGRGRSVESVQSQPQEPVSVPQTLTSTLEHIVGQLDVLTQTV
320 330 340 350 360 370
>>NP_001290176 (OMIM: 609540) WD repeat-containing prote (305 aa)
initn: 284 init1: 122 opt: 282 Z-score: 240.4 bits: 53.6 E(85289): 1.2e-06
Smith-Waterman score: 282; 28.2% identity (60.6% similar) in 216 aa overlap (57-272:63-270)
30 40 50 60 70 80
pF1KB5 PKGNNFLYTNGKCVILRNIDNPALADIYTEHAHQVVVAKYAPSGFYIASGDVSGKLRIWD
: :: . . . ::.......:.::
NP_001 ETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWD
40 50 60 70 80 90
90 100 110 120 130 140
pF1KB5 TTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVVGEGREKFGAVFLWDSGSSVGEITGHN
. ... . . : . .:.. ::. .:. : : . .: .::.. . ..
NP_001 LENGKQIKSIDAGPVDAW--TLAFSPDSQYLAT-GTHVGKVN-IFGVESGKKEYSLDTRG
100 110 120 130 140
150 160 170 180 190 200
pF1KB5 KVINSVDIKQSRPYRLATGSDDNCAAFFEGPPFKFKFTVGDHSRFVNCVRFSPDGNRFAT
: : :. . . : ::.:. :. .:. :. :. :. . . ::::.. ..:
NP_001 KFILSIAYSPDGKY-LASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVT
150 160 170 180 190 200
210 220 230 240 250 260
pF1KB5 ASADGQIYIYDGKTGEKVCALGGSKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVSVN
:: :: : ::: . .. . .:.: : . . ... ::.::..:.:.::. :.:::..
NP_001 ASDDGYIKIYDVQHANLAGTLSG---HASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTR
210 220 230 240 250 260
270 280 290 300 310 320
pF1KB5 SVVSTFPMGSTVLDQQLGCLWQKDHLLSVSLSGYINYLDRNNPSKPLHVIKGHSKSIQCL
. : ::
NP_001 TCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYDCPI
270 280 290 300
>>XP_011520396 (OMIM: 609540) PREDICTED: WD repeat-conta (305 aa)
initn: 284 init1: 122 opt: 282 Z-score: 240.4 bits: 53.6 E(85289): 1.2e-06
Smith-Waterman score: 282; 28.2% identity (60.6% similar) in 216 aa overlap (57-272:63-270)
30 40 50 60 70 80
pF1KB5 PKGNNFLYTNGKCVILRNIDNPALADIYTEHAHQVVVAKYAPSGFYIASGDVSGKLRIWD
: :: . . . ::.......:.::
XP_011 ETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWD
40 50 60 70 80 90
90 100 110 120 130 140
pF1KB5 TTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVVGEGREKFGAVFLWDSGSSVGEITGHN
. ... . . : . .:.. ::. .:. : : . .: .::.. . ..
XP_011 LENGKQIKSIDAGPVDAW--TLAFSPDSQYLAT-GTHVGKVN-IFGVESGKKEYSLDTRG
100 110 120 130 140
150 160 170 180 190 200
pF1KB5 KVINSVDIKQSRPYRLATGSDDNCAAFFEGPPFKFKFTVGDHSRFVNCVRFSPDGNRFAT
: : :. . . : ::.:. :. .:. :. :. :. . . ::::.. ..:
XP_011 KFILSIAYSPDGKY-LASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVT
150 160 170 180 190 200
210 220 230 240 250 260
pF1KB5 ASADGQIYIYDGKTGEKVCALGGSKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVSVN
:: :: : ::: . .. . .:.: : . . ... ::.::..:.:.::. :.:::..
XP_011 ASDDGYIKIYDVQHANLAGTLSG---HASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTR
210 220 230 240 250 260
270 280 290 300 310 320
pF1KB5 SVVSTFPMGSTVLDQQLGCLWQKDHLLSVSLSGYINYLDRNNPSKPLHVIKGHSKSIQCL
. : ::
XP_011 TCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYDCPI
270 280 290 300
606 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 16:06:14 2016 done: Thu Nov 3 16:06:16 2016
Total Scan time: 9.480 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]