FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5110, 638 aa 1>>>pF1KB5110 638 - 638 aa - 638 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.8300+/-0.000468; mu= 13.1776+/- 0.029 mean_var=133.8894+/-26.239, 0's: 0 Z-trim(113.2): 13 B-trim: 238 in 1/55 Lambda= 0.110841 statistics sampled from 22419 (22431) to 22419 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.628), E-opt: 0.2 (0.263), width: 16 Scan time: 10.800 The best scores are: opt bits E(85289) NP_003130 (OMIM: 182180) signal recognition partic ( 638) 4109 669.3 1.1e-191 XP_016873668 (OMIM: 182180) PREDICTED: signal reco ( 634) 3857 629.0 1.5e-179 NP_001171313 (OMIM: 182180) signal recognition par ( 610) 3661 597.6 4.1e-170 >>NP_003130 (OMIM: 182180) signal recognition particle r (638 aa) initn: 4109 init1: 4109 opt: 4109 Z-score: 3562.0 bits: 669.3 E(85289): 1.1e-191 Smith-Waterman score: 4109; 100.0% identity (100.0% similar) in 638 aa overlap (1-638:1-638) 10 20 30 40 50 60 pF1KB5 MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQERGGNNSFTHEALTLKYKLDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQERGGNNSFTHEALTLKYKLDN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 QFELVFVVGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQQSALSLLNGTFDFQNDFLRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QFELVFVVGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQQSALSLLNGTFDFQNDFLRL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LREAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LREAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 GKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGSGGQLQDLDCSSSDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGSGGQLQDLDCSSSDD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 EGAAQNSTKPSATKGTLGGMFGMLKGLVGSKSLSREDMESVLDKMRDHLIAKNVAADIAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 EGAAQNSTKPSATKGTLGGMFGMLKGLVGSKSLSREDMESVLDKMRDHLIAKNVAADIAV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQRRVDMLRDIMDAQRRQRPYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQRRVDMLRDIMDAQRRQRPYV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 VTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPEK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 HGGRTMVQLFEKGYGKDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 HGGRTMVQLFEKGYGKDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLIT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 VNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAA 550 560 570 580 590 600 610 620 630 pF1KB5 ISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALMKA :::::::::::::::::::::::::::::::::::::: NP_003 ISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALMKA 610 620 630 >>XP_016873668 (OMIM: 182180) PREDICTED: signal recognit (634 aa) initn: 3857 init1: 3857 opt: 3857 Z-score: 3344.3 bits: 629.0 E(85289): 1.5e-179 Smith-Waterman score: 3857; 100.0% identity (100.0% similar) in 597 aa overlap (1-597:1-597) 10 20 30 40 50 60 pF1KB5 MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQERGGNNSFTHEALTLKYKLDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQERGGNNSFTHEALTLKYKLDN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 QFELVFVVGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQQSALSLLNGTFDFQNDFLRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFELVFVVGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQQSALSLLNGTFDFQNDFLRL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LREAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LREAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 GKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGSGGQLQDLDCSSSDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGSGGQLQDLDCSSSDD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 EGAAQNSTKPSATKGTLGGMFGMLKGLVGSKSLSREDMESVLDKMRDHLIAKNVAADIAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGAAQNSTKPSATKGTLGGMFGMLKGLVGSKSLSREDMESVLDKMRDHLIAKNVAADIAV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQRRVDMLRDIMDAQRRQRPYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQRRVDMLRDIMDAQRRQRPYV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 VTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPEK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 HGGRTMVQLFEKGYGKDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HGGRTMVQLFEKGYGKDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLIT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 VNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVNVR 550 560 570 580 590 600 610 620 630 pF1KB5 ISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALMKA XP_016 LEAGMGVLHKGAEAARKSWLQRFLFLRGFKMHLT 610 620 630 >>NP_001171313 (OMIM: 182180) signal recognition particl (610 aa) initn: 3914 init1: 3661 opt: 3661 Z-score: 3175.1 bits: 597.6 E(85289): 4.1e-170 Smith-Waterman score: 3862; 95.6% identity (95.6% similar) in 638 aa overlap (1-638:1-610) 10 20 30 40 50 60 pF1KB5 MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQERGGNNSFTHEALTLKYKLDN ::::::::::::::::::::::::::::::::::::::: NP_001 MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQ--------------------- 10 20 30 70 80 90 100 110 120 pF1KB5 QFELVFVVGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQQSALSLLNGTFDFQNDFLRL ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -------VGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQQSALSLLNGTFDFQNDFLRL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 LREAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LREAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 LATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEK 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 GKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGSGGQLQDLDCSSSDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGSGGQLQDLDCSSSDD 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 EGAAQNSTKPSATKGTLGGMFGMLKGLVGSKSLSREDMESVLDKMRDHLIAKNVAADIAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGAAQNSTKPSATKGTLGGMFGMLKGLVGSKSLSREDMESVLDKMRDHLIAKNVAADIAV 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 QLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQRRVDMLRDIMDAQRRQRPYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQRRVDMLRDIMDAQRRQRPYV 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB5 VTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPEK 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB5 HGGRTMVQLFEKGYGKDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HGGRTMVQLFEKGYGKDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLIT 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB5 VNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAA 520 530 540 550 560 570 610 620 630 pF1KB5 ISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALMKA :::::::::::::::::::::::::::::::::::::: NP_001 ISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALMKA 580 590 600 610 638 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 16:06:50 2016 done: Thu Nov 3 16:06:52 2016 Total Scan time: 10.800 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]