FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5122, 514 aa 1>>>pF1KB5122 514 - 514 aa - 514 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.4104+/-0.00132; mu= 1.8621+/- 0.077 mean_var=179.9863+/-39.116, 0's: 0 Z-trim(105.1): 178 B-trim: 0 in 0/51 Lambda= 0.095599 statistics sampled from 8040 (8241) to 8040 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.605), E-opt: 0.2 (0.253), width: 16 Scan time: 3.220 The best scores are: opt bits E(32554) CCDS46961.1 TBL1XR1 gene_id:79718|Hs108|chr3 ( 514) 3472 492.2 5.9e-139 CCDS48078.1 TBL1X gene_id:6907|Hs108|chrX ( 526) 2486 356.2 5.2e-98 CCDS14133.1 TBL1X gene_id:6907|Hs108|chrX ( 577) 2486 356.2 5.6e-98 CCDS14779.1 TBL1Y gene_id:90665|Hs108|chrY ( 522) 2464 353.2 4.2e-97 CCDS2019.1 CIAO1 gene_id:9391|Hs108|chr2 ( 339) 398 68.1 1.8e-11 >>CCDS46961.1 TBL1XR1 gene_id:79718|Hs108|chr3 (514 aa) initn: 3472 init1: 3472 opt: 3472 Z-score: 2608.2 bits: 492.2 E(32554): 5.9e-139 Smith-Waterman score: 3472; 100.0% identity (100.0% similar) in 514 aa overlap (1-514:1-514) 10 20 30 40 50 60 pF1KB5 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY 430 440 450 460 470 480 490 500 510 pF1KB5 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK :::::::::::::::::::::::::::::::::: CCDS46 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK 490 500 510 >>CCDS48078.1 TBL1X gene_id:6907|Hs108|chrX (526 aa) initn: 2400 init1: 2400 opt: 2486 Z-score: 1873.1 bits: 356.2 E(32554): 5.2e-98 Smith-Waterman score: 3118; 86.3% identity (94.9% similar) in 527 aa overlap (1-514:1-526) 10 20 30 40 50 60 pF1KB5 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV :::.:::::::::::::::::::::::::::::::::::::.::::::::::.::::::: CCDS48 MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYV 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAA-- :::.:::::::.::::::::::::::::::::::::::.:.:::::::.::::::::. CCDS48 EAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAAAAAAATAA 70 80 90 100 110 120 120 130 140 150 160 pF1KB5 -----------SQQGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRG :.:. .:: : :.::::: ::.. :::. ::.::.:::: .::.:::: CCDS48 ATAATTTSAGVSHQNPSKNREATVNGEENRAHSV-NNHAKPMEIDGEVEIPSSKATVLRG 130 140 150 160 170 170 180 190 200 210 220 pF1KB5 HESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKD :::::::::::::::::::::::::::::::.:::..:::::::::::::::.::::::: CCDS48 HESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKD 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 VTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVD :::::::..:::::::::::::::::.:::::::::::::::::::::.:::.::::::: CCDS48 VTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVD 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 KTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQG ::::::::::::::::::::::::::::::.:.::::::::::::::.:: :::.::::: CCDS48 KTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQG 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB5 HTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTN ::::::::::::.: ::::::::::::::::::. :.::::::::::::::::::::.:. CCDS48 HTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATS 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB5 NPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVH :::.:.:::::::::::::::..::.: :::::::::::::::::::.:::::::::::: CCDS48 NPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVH 420 430 440 450 460 470 470 480 490 500 510 pF1KB5 IWNTQTGALVHSYRGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK :::::.: :::::::::::::::::: :::::::::::::::::::: CCDS48 IWNTQSGNLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK 480 490 500 510 520 >>CCDS14133.1 TBL1X gene_id:6907|Hs108|chrX (577 aa) initn: 2400 init1: 2400 opt: 2486 Z-score: 1872.5 bits: 356.2 E(32554): 5.6e-98 Smith-Waterman score: 3118; 86.3% identity (94.9% similar) in 527 aa overlap (1-514:52-577) 10 20 30 pF1KB5 MSISSDEVNFLVYRYLQESGFSHSAFTFGI :::.:::::::::::::::::::::::::: CCDS14 QSVLHHFQRLRGREGGSHFINTSSPRGEAKMSITSDEVNFLVYRYLQESGFSHSAFTFGI 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB5 ESHISQSNINGALVPPAALISIIQKGLQYVEAEVSINEDGTLFDGRPIESLSLIDAVMPD :::::::::::.::::::::::.::::::::::.:::::::.:::::::::::::::::: CCDS14 ESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPD 90 100 110 120 130 140 100 110 120 130 pF1KB5 VVQTRQQAYRDKLAQQQAAAAAAAAAAA-------------SQQGSAKNGENTANGEENG ::::::::.:.:::::::.::::::::. :.:. .:: : :.::::: CCDS14 VVQTRQQAFREKLAQQQASAAAAAAAATAAATAATTTSAGVSHQNPSKNREATVNGEENR 150 160 170 180 190 200 140 150 160 170 180 190 pF1KB5 AHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPVSDLLASGSGDSTARIWN ::.. :::. ::.::.:::: .::.:::::::::::::::::::::::::::::::::: CCDS14 AHSV-NNHAKPMEIDGEVEIPSSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWN 210 220 230 240 250 260 200 210 220 230 240 250 pF1KB5 LSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGN :.:::..:::::::::::::::.::::::::::::::..:::::::::::::::::.::: CCDS14 LNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGTLLATGSYDGFARIWTEDGN 270 280 290 300 310 320 260 270 280 290 300 310 pF1KB5 LASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ ::::::::::::::::::.:::.::::::::::::::::::::::::::::::::::::: CCDS14 LASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ 330 340 350 360 370 380 320 330 340 350 360 370 pF1KB5 SNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWS .:.::::::::::::::.:: :::.:::::::::::::::::.: ::::::::::::::: CCDS14 NNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWS 390 400 410 420 430 440 380 390 400 410 420 430 pF1KB5 MKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHT :::. :.::::::::::::::::::::.:.:::.:.:::::::::::::::..::.: :: CCDS14 MKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHT 450 460 470 480 490 500 440 450 460 470 480 490 pF1KB5 LTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRGTGGIFEVCWNAAGDK :::::::::::::::::.:::::::::::::::::.: :::::::::::::::::: ::: CCDS14 LTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGGIFEVCWNARGDK 510 520 530 540 550 560 500 510 pF1KB5 VGASASDGSVCVLDLRK ::::::::::::::::: CCDS14 VGASASDGSVCVLDLRK 570 >>CCDS14779.1 TBL1Y gene_id:90665|Hs108|chrY (522 aa) initn: 2375 init1: 2375 opt: 2464 Z-score: 1856.7 bits: 353.2 E(32554): 4.2e-97 Smith-Waterman score: 3032; 84.9% identity (93.7% similar) in 523 aa overlap (1-512:1-522) 10 20 30 40 50 60 pF1KB5 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV :::.:::::::::::::::::::::::::::::::::::::.::::.:::::.::::::: CCDS14 MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPSALISILQKGLQYV 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAA----- :::.:::.:::.::.::::::::: ::.::::: ::::. .::.::::.:::. : CCDS14 EAEISINKDGTVFDSRPIESLSLIVAVIPDVVQMRQQAFGEKLTQQQASAAATEASAMAK 70 80 90 100 110 120 120 130 140 150 160 pF1KB5 ------AAASQQGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHE :: :::. :: : :.:::::::: : :::. ::.:::::::::::.:::::: CCDS14 AATMTPAAISQQNPPKNREATVNGEENGAHEI-NNHSKPMEIDGDVEIPPNKATVLRGHE 130 140 150 160 170 170 180 190 200 210 220 pF1KB5 SEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVT :::::::::::::::::::::::::::::.:::..:::::::::::::::.::::::::: CCDS14 SEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVT 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 SLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKT ::::::.::::: :::::::::::..::::::::::::::::::::::::..:::::::: CCDS14 SLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKT 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 TIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHT ::::::::::::::::::::::::::::.: ::::::::::::::.:: :.:.::::::: CCDS14 TIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHT 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB5 NEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNP ::::::::::.: ::::::::::::::::::: ::::::::.:::::::::::::.:.:: CCDS14 NEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNP 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB5 NANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIW :...::::::::::::::::..:.: ::: :::::::::::::::.::::::::: :::: CCDS14 NSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIW 420 430 440 450 460 470 470 480 490 500 510 pF1KB5 NTQTGALVHSYRGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK :::.:.:::::.:::::::::::: :::::::::::::::::: CCDS14 NTQSGSLVHSYQGTGGIFEVCWNARGDKVGASASDGSVCVLDL 480 490 500 510 520 >>CCDS2019.1 CIAO1 gene_id:9391|Hs108|chr2 (339 aa) initn: 463 init1: 156 opt: 398 Z-score: 319.5 bits: 68.1 E(32554): 1.8e-11 Smith-Waterman score: 408; 32.4% identity (54.1% similar) in 259 aa overlap (222-469:11-221) 200 210 220 230 240 pF1KB5 TARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTS--LDWNSEGTLLATGSYDGFA ::.. : : :: :::::. . : CCDS20 MKDSLVLLGRVPAHPDSRCWFLAWNPAGTLLASCGGDRRI 10 20 30 40 250 260 270 280 290 300 pF1KB5 RIWTKDGN---LASTLGQ-HKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFP ::: .:. :.:.. :. . . :. ::.. ::. : :: :: :.: CCDS20 RIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCIWK------KNQDD 50 60 70 80 90 310 320 330 340 350 360 pF1KB5 FHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLA :. :. :..:: :::... : :.::::: CCDS20 FE----------------------CV-----------TTLEGHENEVKSVAWAPSGNLLA 100 110 120 370 380 390 400 410 420 pF1KB5 SCSDDMTLKIWSMKQDN---CVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDS .:: : .. .: . ... :: :..:.... . : :. .:::::.:. CCDS20 TCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQE---------LLASASYDD 130 140 150 160 170 430 440 450 460 470 480 pF1KB5 TVRLW--DVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY ::.:. . : .: :: :. :.:.::.:.:. ::: : :. :.:: CCDS20 TVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIWRQYLPGNEQGV 180 190 200 210 220 230 490 500 510 pF1KB5 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK CCDS20 ACSGSDPSWKCICTLSGFHSRTIYDIAWCQLTGALATACGDDAIRVFQEDPNSDPQQPTF 240 250 260 270 280 290 514 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 16:08:13 2016 done: Thu Nov 3 16:08:13 2016 Total Scan time: 3.220 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]