FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5122, 514 aa 1>>>pF1KB5122 514 - 514 aa - 514 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9793+/-0.000535; mu= 10.4559+/- 0.033 mean_var=209.0046+/-46.772, 0's: 0 Z-trim(112.5): 374 B-trim: 0 in 0/53 Lambda= 0.088715 statistics sampled from 20921 (21425) to 20921 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.6), E-opt: 0.2 (0.251), width: 16 Scan time: 8.370 The best scores are: opt bits E(85289) NP_001308123 (OMIM: 270710,602342,608628,616944) F ( 514) 3472 458.3 2.5e-128 XP_011511444 (OMIM: 270710,602342,608628,616944) P ( 514) 3472 458.3 2.5e-128 XP_005247832 (OMIM: 270710,602342,608628,616944) P ( 514) 3472 458.3 2.5e-128 XP_011511443 (OMIM: 270710,602342,608628,616944) P ( 514) 3472 458.3 2.5e-128 XP_016862674 (OMIM: 270710,602342,608628,616944) P ( 514) 3472 458.3 2.5e-128 NP_078941 (OMIM: 270710,602342,608628,616944) F-bo ( 514) 3472 458.3 2.5e-128 XP_011511445 (OMIM: 270710,602342,608628,616944) P ( 514) 3472 458.3 2.5e-128 XP_006713809 (OMIM: 270710,602342,608628,616944) P ( 514) 3472 458.3 2.5e-128 NP_001308122 (OMIM: 270710,602342,608628,616944) F ( 514) 3472 458.3 2.5e-128 NP_001308124 (OMIM: 270710,602342,608628,616944) F ( 427) 2928 388.6 2e-107 NP_001132940 (OMIM: 300196) F-box-like/WD repeat-c ( 526) 2486 332.1 2.4e-90 NP_001132939 (OMIM: 300196) F-box-like/WD repeat-c ( 526) 2486 332.1 2.4e-90 XP_011543873 (OMIM: 300196) PREDICTED: F-box-like/ ( 526) 2486 332.1 2.4e-90 NP_001132938 (OMIM: 300196) F-box-like/WD repeat-c ( 577) 2486 332.2 2.6e-90 NP_005638 (OMIM: 300196) F-box-like/WD repeat-cont ( 577) 2486 332.2 2.6e-90 NP_150600 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 2464 329.3 1.7e-89 NP_599021 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 2464 329.3 1.7e-89 NP_599020 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 2464 329.3 1.7e-89 XP_005262629 (OMIM: 400033) PREDICTED: F-box-like/ ( 536) 2464 329.3 1.7e-89 XP_016885576 (OMIM: 400033) PREDICTED: F-box-like/ ( 540) 2423 324.1 6.6e-88 XP_016885575 (OMIM: 400033) PREDICTED: F-box-like/ ( 577) 2423 324.1 6.9e-88 NP_004795 (OMIM: 604333) probable cytosolic iron-s ( 339) 398 64.6 5.2e-10 NP_004805 (OMIM: 607797) U5 small nuclear ribonucl ( 357) 364 60.3 1.1e-08 NP_001246 (OMIM: 603618) cell division cycle prote ( 499) 328 55.9 3.3e-07 NP_004757 (OMIM: 606990) coatomer subunit beta' [H ( 906) 292 51.6 1.2e-05 NP_115737 (OMIM: 606929) THO complex subunit 3 [Ho ( 351) 279 49.4 2e-05 XP_016863001 (OMIM: 606990) PREDICTED: coatomer su ( 877) 284 50.6 2.3e-05 XP_016865474 (OMIM: 606929) PREDICTED: THO complex ( 263) 275 48.8 2.4e-05 NP_055317 (OMIM: 608330) pre-mRNA-processing facto ( 504) 264 47.7 9.7e-05 NP_065851 (OMIM: 611177,611263) intraflagellar tra ( 777) 266 48.2 0.00011 NP_057347 (OMIM: 603619) fizzy-related protein hom ( 493) 262 47.4 0.00011 XP_005259630 (OMIM: 603619) PREDICTED: fizzy-relat ( 496) 262 47.4 0.00011 NP_001129670 (OMIM: 603619) fizzy-related protein ( 496) 262 47.4 0.00011 NP_003571 (OMIM: 603043) protein FAN isoform 1 [Ho ( 917) 266 48.3 0.00012 XP_016882352 (OMIM: 603619) PREDICTED: fizzy-relat ( 528) 262 47.5 0.00012 NP_001138244 (OMIM: 603043) protein FAN isoform 2 ( 948) 266 48.3 0.00012 XP_011519255 (OMIM: 139130,145500,617024) PREDICTE ( 360) 255 46.4 0.00017 XP_011519465 (OMIM: 604447) PREDICTED: guanine nuc ( 301) 250 45.6 0.00024 NP_001129669 (OMIM: 603619) fizzy-related protein ( 404) 252 46.0 0.00024 XP_011519464 (OMIM: 604447) PREDICTED: guanine nuc ( 353) 250 45.7 0.00027 NP_006569 (OMIM: 604447) guanine nucleotide-bindin ( 353) 250 45.7 0.00027 NP_057278 (OMIM: 604447) guanine nucleotide-bindin ( 395) 250 45.8 0.00029 NP_001151 (OMIM: 602233) apoptotic protease-activa (1194) 253 46.8 0.00044 NP_863658 (OMIM: 602233) apoptotic protease-activa (1205) 253 46.8 0.00044 NP_037361 (OMIM: 602233) apoptotic protease-activa (1237) 253 46.8 0.00045 NP_863651 (OMIM: 602233) apoptotic protease-activa (1248) 253 46.8 0.00045 NP_003380 (OMIM: 602159) coronin-2A [Homo sapiens] ( 525) 245 45.3 0.00053 NP_438171 (OMIM: 602159) coronin-2A [Homo sapiens] ( 525) 245 45.3 0.00053 XP_011517288 (OMIM: 602159) PREDICTED: coronin-2A ( 525) 245 45.3 0.00053 NP_620640 (OMIM: 601787) transcription initiation ( 745) 246 45.6 0.00061 >>NP_001308123 (OMIM: 270710,602342,608628,616944) F-box (514 aa) initn: 3472 init1: 3472 opt: 3472 Z-score: 2425.0 bits: 458.3 E(85289): 2.5e-128 Smith-Waterman score: 3472; 100.0% identity (100.0% similar) in 514 aa overlap (1-514:1-514) 10 20 30 40 50 60 pF1KB5 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY 430 440 450 460 470 480 490 500 510 pF1KB5 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK :::::::::::::::::::::::::::::::::: NP_001 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK 490 500 510 >>XP_011511444 (OMIM: 270710,602342,608628,616944) PREDI (514 aa) initn: 3472 init1: 3472 opt: 3472 Z-score: 2425.0 bits: 458.3 E(85289): 2.5e-128 Smith-Waterman score: 3472; 100.0% identity (100.0% similar) in 514 aa overlap (1-514:1-514) 10 20 30 40 50 60 pF1KB5 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY 430 440 450 460 470 480 490 500 510 pF1KB5 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK :::::::::::::::::::::::::::::::::: XP_011 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK 490 500 510 >>XP_005247832 (OMIM: 270710,602342,608628,616944) PREDI (514 aa) initn: 3472 init1: 3472 opt: 3472 Z-score: 2425.0 bits: 458.3 E(85289): 2.5e-128 Smith-Waterman score: 3472; 100.0% identity (100.0% similar) in 514 aa overlap (1-514:1-514) 10 20 30 40 50 60 pF1KB5 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY 430 440 450 460 470 480 490 500 510 pF1KB5 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK :::::::::::::::::::::::::::::::::: XP_005 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK 490 500 510 >>XP_011511443 (OMIM: 270710,602342,608628,616944) PREDI (514 aa) initn: 3472 init1: 3472 opt: 3472 Z-score: 2425.0 bits: 458.3 E(85289): 2.5e-128 Smith-Waterman score: 3472; 100.0% identity (100.0% similar) in 514 aa overlap (1-514:1-514) 10 20 30 40 50 60 pF1KB5 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY 430 440 450 460 470 480 490 500 510 pF1KB5 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK :::::::::::::::::::::::::::::::::: XP_011 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK 490 500 510 >>XP_016862674 (OMIM: 270710,602342,608628,616944) PREDI (514 aa) initn: 3472 init1: 3472 opt: 3472 Z-score: 2425.0 bits: 458.3 E(85289): 2.5e-128 Smith-Waterman score: 3472; 100.0% identity (100.0% similar) in 514 aa overlap (1-514:1-514) 10 20 30 40 50 60 pF1KB5 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY 430 440 450 460 470 480 490 500 510 pF1KB5 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK :::::::::::::::::::::::::::::::::: XP_016 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK 490 500 510 >>NP_078941 (OMIM: 270710,602342,608628,616944) F-box-li (514 aa) initn: 3472 init1: 3472 opt: 3472 Z-score: 2425.0 bits: 458.3 E(85289): 2.5e-128 Smith-Waterman score: 3472; 100.0% identity (100.0% similar) in 514 aa overlap (1-514:1-514) 10 20 30 40 50 60 pF1KB5 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY 430 440 450 460 470 480 490 500 510 pF1KB5 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK :::::::::::::::::::::::::::::::::: NP_078 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK 490 500 510 >>XP_011511445 (OMIM: 270710,602342,608628,616944) PREDI (514 aa) initn: 3472 init1: 3472 opt: 3472 Z-score: 2425.0 bits: 458.3 E(85289): 2.5e-128 Smith-Waterman score: 3472; 100.0% identity (100.0% similar) in 514 aa overlap (1-514:1-514) 10 20 30 40 50 60 pF1KB5 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY 430 440 450 460 470 480 490 500 510 pF1KB5 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK :::::::::::::::::::::::::::::::::: XP_011 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK 490 500 510 >>XP_006713809 (OMIM: 270710,602342,608628,616944) PREDI (514 aa) initn: 3472 init1: 3472 opt: 3472 Z-score: 2425.0 bits: 458.3 E(85289): 2.5e-128 Smith-Waterman score: 3472; 100.0% identity (100.0% similar) in 514 aa overlap (1-514:1-514) 10 20 30 40 50 60 pF1KB5 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY 430 440 450 460 470 480 490 500 510 pF1KB5 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK :::::::::::::::::::::::::::::::::: XP_006 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK 490 500 510 >>NP_001308122 (OMIM: 270710,602342,608628,616944) F-box (514 aa) initn: 3472 init1: 3472 opt: 3472 Z-score: 2425.0 bits: 458.3 E(85289): 2.5e-128 Smith-Waterman score: 3472; 100.0% identity (100.0% similar) in 514 aa overlap (1-514:1-514) 10 20 30 40 50 60 pF1KB5 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY 430 440 450 460 470 480 490 500 510 pF1KB5 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK :::::::::::::::::::::::::::::::::: NP_001 RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK 490 500 510 >>NP_001308124 (OMIM: 270710,602342,608628,616944) F-box (427 aa) initn: 2928 init1: 2928 opt: 2928 Z-score: 2049.6 bits: 388.6 E(85289): 2e-107 Smith-Waterman score: 2928; 100.0% identity (100.0% similar) in 427 aa overlap (88-514:1-427) 60 70 80 90 100 110 pF1KB5 QYVEAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAA :::::::::::::::::::::::::::::: NP_001 MPDVVQTRQQAYRDKLAQQQAAAAAAAAAA 10 20 30 120 130 140 150 160 170 pF1KB5 ASQQGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASQQGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAW 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB5 NPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEG 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB5 TLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHT 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB5 GEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKW 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB5 DPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLAS 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB5 ASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALV 340 350 360 370 380 390 480 490 500 510 pF1KB5 HSYRGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK ::::::::::::::::::::::::::::::::::::: NP_001 HSYRGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK 400 410 420 514 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 16:08:14 2016 done: Thu Nov 3 16:08:15 2016 Total Scan time: 8.370 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]