FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5126, 342 aa 1>>>pF1KB5126 342 - 342 aa - 342 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9300+/-0.000304; mu= 14.5323+/- 0.019 mean_var=132.6243+/-28.862, 0's: 0 Z-trim(119.7): 200 B-trim: 526 in 2/55 Lambda= 0.111369 statistics sampled from 33698 (34002) to 33698 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.748), E-opt: 0.2 (0.399), width: 16 Scan time: 8.090 The best scores are: opt bits E(85289) NP_077007 (OMIM: 611734) methylosome protein 50 is ( 342) 2341 387.2 2.7e-107 NP_001303992 (OMIM: 611734) methylosome protein 50 ( 340) 2312 382.6 6.8e-106 NP_001303991 (OMIM: 611734) methylosome protein 50 ( 354) 1832 305.5 1.1e-82 NP_001303993 (OMIM: 611734) methylosome protein 50 ( 278) 1252 212.2 1.1e-54 NP_001186706 (OMIM: 614784,615973) POC1 centriolar ( 436) 244 50.4 8.4e-06 NP_758440 (OMIM: 614784,615973) POC1 centriolar pr ( 478) 244 50.5 8.9e-06 NP_000279 (OMIM: 215100,266500,601757,614879) pero ( 323) 231 48.2 2.9e-05 XP_005267076 (OMIM: 215100,266500,601757,614879) P ( 285) 229 47.8 3.4e-05 NP_004805 (OMIM: 607797) U5 small nuclear ribonucl ( 357) 217 46.0 0.00015 XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655) 202 43.9 0.0012 XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655) 202 43.9 0.0012 NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655) 202 43.9 0.0012 XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658) 202 43.9 0.0012 XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672) 202 43.9 0.0012 XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672) 202 43.9 0.0012 XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672) 202 43.9 0.0012 XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675) 202 43.9 0.0012 XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675) 202 43.9 0.0012 XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675) 202 43.9 0.0012 XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675) 202 43.9 0.0012 NP_001287673 (OMIM: 610257) protein transport prot (1067) 200 43.8 0.002 NP_001070674 (OMIM: 610257) protein transport prot (1106) 200 43.8 0.0021 NP_001287674 (OMIM: 610257) protein transport prot (1166) 200 43.8 0.0022 NP_057295 (OMIM: 610257) protein transport protein (1181) 200 43.8 0.0022 NP_001177978 (OMIM: 610257) protein transport prot (1200) 200 43.9 0.0022 NP_001305048 (OMIM: 610257) protein transport prot (1205) 200 43.9 0.0022 NP_001070676 (OMIM: 610257) protein transport prot (1205) 200 43.9 0.0022 NP_001305049 (OMIM: 610257) protein transport prot (1220) 200 43.9 0.0022 NP_001070675 (OMIM: 610257) protein transport prot (1220) 200 43.9 0.0022 NP_001315 (OMIM: 600369) cleavage stimulation fact ( 431) 187 41.3 0.0048 NP_001028694 (OMIM: 600369) cleavage stimulation f ( 431) 187 41.3 0.0048 NP_001028693 (OMIM: 600369) cleavage stimulation f ( 431) 187 41.3 0.0048 XP_011526902 (OMIM: 600369) PREDICTED: cleavage st ( 431) 187 41.3 0.0048 XP_011531866 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 183 40.3 0.0051 XP_011531865 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 183 40.3 0.0051 XP_011531867 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 183 40.3 0.0051 NP_942593 (OMIM: 610767,611081) autophagy-related ( 444) 186 41.1 0.0054 XP_005246143 (OMIM: 610767,611081) PREDICTED: auto ( 463) 186 41.1 0.0056 XP_005246141 (OMIM: 610767,611081) PREDICTED: auto ( 480) 186 41.2 0.0057 NP_001177196 (OMIM: 610767,611081) autophagy-relat ( 491) 186 41.2 0.0058 XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 ( 300) 183 40.4 0.0059 NP_001177195 (OMIM: 610767,611081) autophagy-relat ( 523) 186 41.2 0.0061 XP_006712671 (OMIM: 610767,611081) PREDICTED: auto ( 540) 186 41.2 0.0062 XP_011531863 (OMIM: 614783,614813) PREDICTED: POC1 ( 326) 183 40.5 0.0062 NP_060444 (OMIM: 610767,611081) autophagy-related ( 588) 186 41.3 0.0066 NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359) 183 40.5 0.0066 NP_110430 (OMIM: 610767,611081) autophagy-related ( 607) 186 41.3 0.0067 XP_011531862 (OMIM: 614783,614813) PREDICTED: POC1 ( 374) 183 40.5 0.0068 XP_005246139 (OMIM: 610767,611081) PREDICTED: auto ( 624) 186 41.3 0.0068 NP_056241 (OMIM: 614783,614813) POC1 centriolar pr ( 407) 183 40.6 0.0072 >>NP_077007 (OMIM: 611734) methylosome protein 50 isofor (342 aa) initn: 2341 init1: 2341 opt: 2341 Z-score: 2047.3 bits: 387.2 E(85289): 2.7e-107 Smith-Waterman score: 2341; 100.0% identity (100.0% similar) in 342 aa overlap (1-342:1-342) 10 20 30 40 50 60 pF1KB5 MRKETPPPLVPPAAREWNLPPNAPACMERQLEAARYRSDGALLLGASSLSGRCWAGSLWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 MRKETPPPLVPPAAREWNLPPNAPACMERQLEAARYRSDGALLLGASSLSGRCWAGSLWL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 FKDPCAAPNEGFCSAGVQTEAGVADLTWVGERGILVASDSGAVELWELDENETLIVSKFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 FKDPCAAPNEGFCSAGVQTEAGVADLTWVGERGILVASDSGAVELWELDENETLIVSKFC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KYEHDDIVSTVSVLSSGTQAVSGSKDICIKVWDLAQQVVLSSYRAHAAQVTCVAASPHKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 KYEHDDIVSTVSVLSSGTQAVSGSKDICIKVWDLAQQVVLSSYRAHAAQVTCVAASPHKD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SVFLSCSEDNRILLWDTRCPKPASQIGCSAPGYLPTSLAWHPQQSEVFVFGDENGTVSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 SVFLSCSEDNRILLWDTRCPKPASQIGCSAPGYLPTSLAWHPQQSEVFVFGDENGTVSLV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DTKSTSCVLSSAVHSQCVTGLVFSPHSVPFLASLSEDCSLAVLDSSLSELFRSQAHRDFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 DTKSTSCVLSSAVHSQCVTGLVFSPHSVPFLASLSEDCSLAVLDSSLSELFRSQAHRDFV 250 260 270 280 290 300 310 320 330 340 pF1KB5 RDATWSPLNHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE :::::::::::::::::::::::::::::::::::::::::: NP_077 RDATWSPLNHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE 310 320 330 340 >>NP_001303992 (OMIM: 611734) methylosome protein 50 iso (340 aa) initn: 2312 init1: 1971 opt: 2312 Z-score: 2022.1 bits: 382.6 E(85289): 6.8e-106 Smith-Waterman score: 2312; 99.4% identity (99.4% similar) in 342 aa overlap (1-342:1-340) 10 20 30 40 50 60 pF1KB5 MRKETPPPLVPPAAREWNLPPNAPACMERQLEAARYRSDGALLLGASSLSGRCWAGSLWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRKETPPPLVPPAAREWNLPPNAPACMERQLEAARYRSDGALLLGASSLSGRCWAGSLWL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 FKDPCAAPNEGFCSAGVQTEAGVADLTWVGERGILVASDSGAVELWELDENETLIVSKFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKDPCAAPNEGFCSAGVQTEAGVADLTWVGERGILVASDSGAVELWELDENETLIVSKFC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KYEHDDIVSTVSVLSSGTQAVSGSKDICIKVWDLAQQVVLSSYRAHAAQVTCVAASPHKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KYEHDDIVSTVSVLSSGTQAVSGSKDICIKVWDLAQQVVLSSYRAHAAQVTCVAASPHKD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SVFLSCSEDNRILLWDTRCPKPASQIGCSAPGYLPTSLAWHPQQSEVFVFGDENGTVSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVFLSCSEDNRILLWDTRCPKPASQIGCSAPGYLPTSLAWHPQQSEVFVFGDENGTVSLV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DTKSTSCVLSSAVHSQCVTGLVFSPHSVPFLASLSEDCSLAVLDSSLSELFRSQAHRDFV :::::::::::::::::::::::::::::::::::::::::::::::::: :::::::: NP_001 DTKSTSCVLSSAVHSQCVTGLVFSPHSVPFLASLSEDCSLAVLDSSLSEL--SQAHRDFV 250 260 270 280 290 310 320 330 340 pF1KB5 RDATWSPLNHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE :::::::::::::::::::::::::::::::::::::::::: NP_001 RDATWSPLNHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE 300 310 320 330 340 >>NP_001303991 (OMIM: 611734) methylosome protein 50 iso (354 aa) initn: 2327 init1: 1827 opt: 1832 Z-score: 1605.1 bits: 305.5 E(85289): 1.1e-82 Smith-Waterman score: 2307; 96.6% identity (96.6% similar) in 354 aa overlap (1-342:1-354) 10 20 30 40 50 60 pF1KB5 MRKETPPPLVPPAAREWNLPPNAPACMERQLEAARYRSDGALLLGASSLSGRCWAGSLWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRKETPPPLVPPAAREWNLPPNAPACMERQLEAARYRSDGALLLGASSLSGRCWAGSLWL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 FKDPCAAPNEGFCSAGVQTEAGVADLTWVGERGILVASDSGAVELWELDENETLIVSKFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKDPCAAPNEGFCSAGVQTEAGVADLTWVGERGILVASDSGAVELWELDENETLIVSKFC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KYEHDDIVSTVSVLSSGTQAVSGSKDICIKVWDLAQQVVLSSYRAHAAQVTCVAASPHKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KYEHDDIVSTVSVLSSGTQAVSGSKDICIKVWDLAQQVVLSSYRAHAAQVTCVAASPHKD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SVFLSCSEDNRILLWDTRCPKPASQIGCSAPGYLPTSLAWHPQQSEVFVFGDENGTVSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVFLSCSEDNRILLWDTRCPKPASQIGCSAPGYLPTSLAWHPQQSEVFVFGDENGTVSLV 190 200 210 220 230 240 250 260 270 280 pF1KB5 DTKSTSCVLSSAVHSQCVTGLVFSPH------------SVPFLASLSEDCSLAVLDSSLS :::::::::::::::::::::::::: :::::::::::::::::::::: NP_001 DTKSTSCVLSSAVHSQCVTGLVFSPHRLDLSQPSPPSDSVPFLASLSEDCSLAVLDSSLS 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB5 ELFRSQAHRDFVRDATWSPLNHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELFRSQAHRDFVRDATWSPLNHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE 310 320 330 340 350 >>NP_001303993 (OMIM: 611734) methylosome protein 50 iso (278 aa) initn: 1229 init1: 1229 opt: 1252 Z-score: 1102.7 bits: 212.2 E(85289): 1.1e-54 Smith-Waterman score: 1790; 81.3% identity (81.3% similar) in 342 aa overlap (1-342:1-278) 10 20 30 40 50 60 pF1KB5 MRKETPPPLVPPAAREWNLPPNAPACMERQLEAARYRSDGALLLGASSLSGRCWAGSLWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRKETPPPLVPPAAREWNLPPNAPACMERQLEAARYRSDGALLLGASSLSGRCWAGSLWL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 FKDPCAAPNEGFCSAGVQTEAGVADLTWVGERGILVASDSGAVELWELDENETLIVSKFC :::::::::::::::::::::::::::::::::::::::: NP_001 FKDPCAAPNEGFCSAGVQTEAGVADLTWVGERGILVASDS-------------------- 70 80 90 100 130 140 150 160 170 180 pF1KB5 KYEHDDIVSTVSVLSSGTQAVSGSKDICIKVWDLAQQVVLSSYRAHAAQVTCVAASPHKD :::::::::::::::: NP_001 --------------------------------------------AHAAQVTCVAASPHKD 110 190 200 210 220 230 240 pF1KB5 SVFLSCSEDNRILLWDTRCPKPASQIGCSAPGYLPTSLAWHPQQSEVFVFGDENGTVSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVFLSCSEDNRILLWDTRCPKPASQIGCSAPGYLPTSLAWHPQQSEVFVFGDENGTVSLV 120 130 140 150 160 170 250 260 270 280 290 300 pF1KB5 DTKSTSCVLSSAVHSQCVTGLVFSPHSVPFLASLSEDCSLAVLDSSLSELFRSQAHRDFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTKSTSCVLSSAVHSQCVTGLVFSPHSVPFLASLSEDCSLAVLDSSLSELFRSQAHRDFV 180 190 200 210 220 230 310 320 330 340 pF1KB5 RDATWSPLNHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE :::::::::::::::::::::::::::::::::::::::::: NP_001 RDATWSPLNHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE 240 250 260 270 >>NP_001186706 (OMIM: 614784,615973) POC1 centriolar pro (436 aa) initn: 143 init1: 87 opt: 244 Z-score: 225.1 bits: 50.4 E(85289): 8.4e-06 Smith-Waterman score: 244; 28.9% identity (58.7% similar) in 235 aa overlap (93-323:30-253) 70 80 90 100 110 120 pF1KB5 DPCAAPNEGFCSAGVQTEAGVADLTWVGERGILVASDSG--AVELWELDENETLIVSKFC : :.:: : .:.:: :. .:: NP_001 MLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKR-----GKFS 10 20 30 40 50 130 140 150 160 170 pF1KB5 KYE-HDDIVSTVSVLSSGTQAVSGSKDICIKVWDLAQQVVLSSYRAHAAQVTCVAASPHK ... : : .:. ..: ...:.: ::::.. .: : : :. : :. :: NP_001 EFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPD- 60 70 80 90 100 110 180 190 200 210 220 230 pF1KB5 DSVFLSCSEDNRILLWDTRCPKPASQIGCSAPGYLPTSLAWHPQQSEVFVFGDENGTVSL ...:::::. : .::: . ..... :. :. . . ..:. . . :... ::.. NP_001 GRLIVSCSEDKTIKIWDTTNKQCVNNFSDSV-GF-ANFVDFNPSGTCIASAGSDQ-TVKV 120 130 140 150 160 170 240 250 260 270 280 290 pF1KB5 VDTKSTSCVLSSAVHSQCVTGLVFSPHSVPFLASLSEDCSLAVLDSSLSELFRS-QAHRD :.. .. . ::: :. . : : : .: . : : .: .:: ..:. . :.: NP_001 WDVRVNKLLQHYQVHSGGVNCISFHP-SGNYLITASSDGTLKILDLLEGRLIYTLQGHTG 180 190 200 210 220 300 310 320 330 340 pF1KB5 FVRDATWSPLNHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE : ...: . :... : : ::. NP_001 PVFTVSFSK-GGELFASGGADTQVLLWRTNFDELHCKGLTKRNLKRLHFDSPPHLLDIYP 230 240 250 260 270 280 >>NP_758440 (OMIM: 614784,615973) POC1 centriolar protei (478 aa) initn: 143 init1: 87 opt: 244 Z-score: 224.7 bits: 50.5 E(85289): 8.9e-06 Smith-Waterman score: 244; 28.9% identity (58.7% similar) in 235 aa overlap (93-323:72-295) 70 80 90 100 110 120 pF1KB5 DPCAAPNEGFCSAGVQTEAGVADLTWVGERGILVASDSG--AVELWELDENETLIVSKFC : :.:: : .:.:: :. .:: NP_758 LMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKR-----GKFS 50 60 70 80 90 130 140 150 160 170 pF1KB5 KYE-HDDIVSTVSVLSSGTQAVSGSKDICIKVWDLAQQVVLSSYRAHAAQVTCVAASPHK ... : : .:. ..: ...:.: ::::.. .: : : :. : :. :: NP_758 EFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPD- 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB5 DSVFLSCSEDNRILLWDTRCPKPASQIGCSAPGYLPTSLAWHPQQSEVFVFGDENGTVSL ...:::::. : .::: . ..... :. :. . . ..:. . . :... ::.. NP_758 GRLIVSCSEDKTIKIWDTTNKQCVNNFSDSV-GF-ANFVDFNPSGTCIASAGSDQ-TVKV 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB5 VDTKSTSCVLSSAVHSQCVTGLVFSPHSVPFLASLSEDCSLAVLDSSLSELFRS-QAHRD :.. .. . ::: :. . : : : .: . : : .: .:: ..:. . :.: NP_758 WDVRVNKLLQHYQVHSGGVNCISFHP-SGNYLITASSDGTLKILDLLEGRLIYTLQGHTG 220 230 240 250 260 270 300 310 320 330 340 pF1KB5 FVRDATWSPLNHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE : ...: . :... : : ::. NP_758 PVFTVSFSK-GGELFASGGADTQVLLWRTNFDELHCKGLTKRNLKRLHFDSPPHLLDIYP 280 290 300 310 320 330 >>NP_000279 (OMIM: 215100,266500,601757,614879) peroxiso (323 aa) initn: 187 init1: 131 opt: 231 Z-score: 215.4 bits: 48.2 E(85289): 2.9e-05 Smith-Waterman score: 231; 25.3% identity (51.2% similar) in 293 aa overlap (40-322:30-311) 10 20 30 40 50 60 pF1KB5 VPPAAREWNLPPNAPACMERQLEAARYRSDGALLLGASSLSGRCWAGSLWLFKDPCAAPN : : .... : :.: :. :: : NP_000 MSAVCGGAARMLRTPGRHGYAAEFSPYLPGRLACATAQHYGIAGCGTL-LILDPDEAGL 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 EGFCSAGVQTEAGVADLTWV--GERGILVASDSGAVELWELDENE-TLIVSKFCKYEHDD . : : . . :. :.:: .:. ... : .:...::. . : : : :: . NP_000 RLFRS--FDWNDGLFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYK----EHAQ 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 IVSTVS-VLSSGTQ-AVSGSKDICIKVWDLAQQVVLSSYRAHAAQVTCVAASPHKDSVFL : .:. . : : .:::: : .:.:: . : ..:.: . . . ::: . : NP_000 EVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKSLCTFRGHESIIYSTIWSPHIPGCFA 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 SCSEDNRILLWDTRCPKPASQIGCSAPGYLPTSLA--WHPQQSEVFVFGDENGTVSLVDT : : :. . .::.. :. . :.. :. : . ...: : . .. : NP_000 SASGDQTLRIWDVK----AAGVRIVIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDL 180 190 200 210 220 250 260 270 280 290 pF1KB5 KSTSC-VLSSAVHSQCVTGLVFSPHSVPFLASLSEDCSLAVLDSSL--SELFRSQAHRDF ... :. :. . . ::: . ::: : : .. . : : : . : .: NP_000 RNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDSLLETVEHHTEF 230 240 250 260 270 280 300 310 320 330 340 pF1KB5 VRDATWSPLNHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE . .: . . .. .::. . NP_000 TCGLDFSLQSPTQVADCSWDETIKIYDPACLTIPA 290 300 310 320 >>XP_005267076 (OMIM: 215100,266500,601757,614879) PREDI (285 aa) initn: 187 init1: 131 opt: 229 Z-score: 214.3 bits: 47.8 E(85289): 3.4e-05 Smith-Waterman score: 229; 25.6% identity (51.6% similar) in 277 aa overlap (56-322:8-273) 30 40 50 60 70 80 pF1KB5 CMERQLEAARYRSDGALLLGASSLSGRCWAGSLWLFKDPCAAPNEGFCSAGVQTEAGVAD :.: :. :: : . : : . . :. : XP_005 MHTFASCGTL-LILDPDEAGLRLFRS--FDWNDGLFD 10 20 30 90 100 110 120 130 140 pF1KB5 LTWV--GERGILVASDSGAVELWELDENE-TLIVSKFCKYEHDDIVSTVS-VLSSGTQ-A .:: .:. ... : .:...::. . : : : :: . : .:. . : : . XP_005 VTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYK----EHAQEVYSVDWSQTRGEQLV 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB5 VSGSKDICIKVWDLAQQVVLSSYRAHAAQVTCVAASPHKDSVFLSCSEDNRILLWDTRCP :::: : .:.:: . : ..:.: . . . ::: . : : : :. . .::.. XP_005 VSGSWDQTVKLWDPTVGKSLCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWDVK-- 100 110 120 130 140 210 220 230 240 250 pF1KB5 KPASQIGCSAPGYLPTSLA--WHPQQSEVFVFGDENGTVSLVDTKSTSC-VLSSAVHSQC :. . :.. :. : . ...: : . .. : ... :. :. XP_005 --AAGVRIVIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPVFELLGHTYA 150 160 170 180 190 200 260 270 280 290 300 310 pF1KB5 VTGLVFSPHSVPFLASLSEDCSLAVLDSSL--SELFRSQAHRDFVRDATWSPLNHSLLTT . . ::: . ::: : : .. . : : : . : .:. .: . . .. XP_005 IRRVKFSPFHASVLASCSYDFTVRFWNFSKPDSLLETVEHHTEFTCGLDFSLQSPTQVAD 210 220 230 240 250 260 320 330 340 pF1KB5 VGWDHQVVHHVVPTEPLPAPGPASVTE .::. . XP_005 CSWDETIKIYDPACLTIPA 270 280 >>NP_004805 (OMIM: 607797) U5 small nuclear ribonucleopr (357 aa) initn: 260 init1: 89 opt: 217 Z-score: 202.7 bits: 46.0 E(85289): 0.00015 Smith-Waterman score: 217; 27.4% identity (57.4% similar) in 197 aa overlap (90-280:163-351) 60 70 80 90 100 110 pF1KB5 LFKDPCAAPNEGFCSAGVQTEAGVADLTWVGERGILVASDSGAVELWELDENETLIVSKF : . . ..::.:.:.::.. .. .. . NP_004 VAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQT--- 140 150 160 170 180 120 130 140 150 160 170 pF1KB5 CKYEHDDIVSTVSVLSSGTQAVSGSKDICIKVWDLAQQVVLSSYRAHAAQVTCVAASPHK ... : .:. ... : .::. : :::::: :. . ..:.:: .:: .. : . NP_004 --FQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSS-E 190 200 210 220 230 240 180 190 200 210 220 230 pF1KB5 DSVFLSCSEDNRILLWDTR--CPKPAS-QIGCSAPGYLPTSL---AWHPQQSEVFVFGDE : .:: . :: . .::.: :: .: . . .: .: :. :.. . :. NP_004 GSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAA-GSA 250 260 270 280 290 300 240 250 260 270 280 290 pF1KB5 NGTVSLVDTKSTSCVLSSAVHSQCVTGLVFSPHSVPFLASLSEDCSLAVLDSSLSELFRS . : . :: : . . :. .. ..: : :.. : : : : NP_004 DRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDE-PIIISASSDKRLYMGEIQ 310 320 330 340 350 300 310 320 330 340 pF1KB5 QAHRDFVRDATWSPLNHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE >>XP_016878353 (OMIM: 602703,616212) PREDICTED: katanin (655 aa) initn: 154 init1: 107 opt: 202 Z-score: 186.6 bits: 43.9 E(85289): 0.0012 Smith-Waterman score: 202; 25.8% identity (59.6% similar) in 178 aa overlap (91-265:75-241) 70 80 90 100 110 120 pF1KB5 FKDPCAAPNEGFCSAGVQTEAGVADLTWVGERGILVASDSGAVELWELDENETLIVSKFC :. :...:.::....:.:. . : . XP_016 VNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTL--- 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 KYEHDDIVSTVSVLSSGTQAVSGSKDICIKVWDLAQQVVLSSYRAHAAQVTCVAASPHKD . : . ... : ..:::.: ::.::. .. . ::.:. : :. :: : XP_016 -MGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSP--D 110 120 130 140 150 190 200 210 220 230 pF1KB5 SVFL-SCSEDNRILLWDTRCPKPASQIGCSAPGYL-PTSLA-WHPQQSEVFVFGDENGTV . .: : ..:. . ::: : :.. ::. :.... .::.. ... :. . :. XP_016 GKWLASAADDHTVKLWDLTAGKMMSEF----PGHTGPVNVVEFHPNEY-LLASGSSDRTI 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB5 SLVDTKSTSCVLSSAVHSQCVTGLVFSPHSVPFLASLSEDCSLAVLDSSLSELFRSQAHR . : .. . : . : ...:.: XP_016 RFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWG 220 230 240 250 260 270 342 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:19:00 2016 done: Sat Nov 5 06:19:02 2016 Total Scan time: 8.090 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]