FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5134, 796 aa 1>>>pF1KB5134 796 - 796 aa - 796 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5939+/-0.000446; mu= 19.3252+/- 0.028 mean_var=80.9727+/-16.264, 0's: 0 Z-trim(111.5): 412 B-trim: 102 in 1/52 Lambda= 0.142530 statistics sampled from 19693 (20121) to 19693 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.587), E-opt: 0.2 (0.236), width: 16 Scan time: 12.010 The best scores are: opt bits E(85289) NP_001788 (OMIM: 600023) cadherin-11 isoform 1 pre ( 796) 5314 1103.2 0 XP_011521105 (OMIM: 600023) PREDICTED: cadherin-11 ( 796) 5314 1103.2 0 XP_005255820 (OMIM: 600023) PREDICTED: cadherin-11 ( 796) 5314 1103.2 0 XP_005255819 (OMIM: 600023) PREDICTED: cadherin-11 ( 796) 5314 1103.2 0 XP_005255818 (OMIM: 600023) PREDICTED: cadherin-11 ( 796) 5314 1103.2 0 NP_001317505 (OMIM: 600023) cadherin-11 isoform 3 ( 670) 4436 922.6 0 NP_001295321 (OMIM: 600023) cadherin-11 isoform 2 ( 693) 4203 874.7 0 NP_001787 (OMIM: 603008) cadherin-8 preproprotein ( 799) 3582 747.1 6.9e-215 XP_016864418 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 3100 648.0 4.7e-185 XP_016864419 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 3100 648.0 4.7e-185 XP_016864413 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 3100 648.0 4.7e-185 XP_006714498 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 3100 648.0 4.7e-185 XP_005248285 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 3100 648.0 4.7e-185 XP_016864415 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 3100 648.0 4.7e-185 XP_016864420 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 3100 648.0 4.7e-185 XP_016864414 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 3100 648.0 4.7e-185 XP_016864421 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 3100 648.0 4.7e-185 NP_004925 (OMIM: 603019) cadherin-18 isoform 1 pre ( 790) 3100 648.0 4.7e-185 NP_001278885 (OMIM: 603019) cadherin-18 isoform 1 ( 790) 3100 648.0 4.7e-185 XP_016864416 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 3100 648.0 4.7e-185 XP_016864417 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 3100 648.0 4.7e-185 NP_006718 (OMIM: 604555) cadherin-10 isoform 1 pre ( 788) 3091 646.1 1.7e-184 XP_011512225 (OMIM: 604555) PREDICTED: cadherin-10 ( 788) 3091 646.1 1.7e-184 XP_011512223 (OMIM: 603007) PREDICTED: cadherin-6 ( 790) 3085 644.9 4e-184 NP_004923 (OMIM: 603007) cadherin-6 preproprotein ( 790) 3085 644.9 4e-184 XP_016864399 (OMIM: 603007) PREDICTED: cadherin-6 ( 790) 3085 644.9 4e-184 XP_016881012 (OMIM: 605806) PREDICTED: cadherin-7 ( 785) 3074 642.6 1.9e-183 NP_004352 (OMIM: 605806) cadherin-7 isoform 1 prep ( 785) 3074 642.6 1.9e-183 NP_387450 (OMIM: 605806) cadherin-7 isoform 1 prep ( 785) 3074 642.6 1.9e-183 XP_005255817 (OMIM: 603008) PREDICTED: cadherin-8 ( 711) 3052 638.1 4e-182 NP_057363 (OMIM: 609974) cadherin-9 preproprotein ( 789) 3026 632.8 1.8e-180 XP_011512229 (OMIM: 600562) PREDICTED: cadherin-12 ( 794) 2987 624.7 4.6e-178 XP_016864409 (OMIM: 600562) PREDICTED: cadherin-12 ( 794) 2987 624.7 4.6e-178 NP_001304156 (OMIM: 600562) cadherin-12 isoform 1 ( 794) 2987 624.7 4.6e-178 XP_016864410 (OMIM: 600562) PREDICTED: cadherin-12 ( 794) 2987 624.7 4.6e-178 NP_004052 (OMIM: 600562) cadherin-12 isoform 1 pre ( 794) 2987 624.7 4.6e-178 NP_114097 (OMIM: 605807) cadherin-20 preproprotein ( 801) 2984 624.1 7.2e-178 XP_016878318 (OMIM: 603008) PREDICTED: cadherin-8 ( 621) 2931 613.2 1.1e-174 XP_011512230 (OMIM: 603019) PREDICTED: cadherin-18 ( 724) 2914 609.7 1.4e-173 NP_001304153 (OMIM: 604555) cadherin-10 isoform 3 ( 786) 2525 529.7 1.8e-149 XP_016864404 (OMIM: 604555) PREDICTED: cadherin-10 ( 786) 2525 529.7 1.8e-149 XP_011512231 (OMIM: 603019) PREDICTED: cadherin-18 ( 622) 2467 517.7 5.9e-146 NP_001304143 (OMIM: 605806) cadherin-7 isoform 2 p ( 630) 2420 508.1 4.8e-143 NP_067071 (OMIM: 609920) cadherin-22 precursor [Ho ( 828) 2416 507.3 1.1e-142 XP_011527296 (OMIM: 609920) PREDICTED: cadherin-22 ( 828) 2416 507.3 1.1e-142 XP_016864400 (OMIM: 603007) PREDICTED: cadherin-6 ( 663) 2413 506.7 1.4e-142 XP_016864423 (OMIM: 603019) PREDICTED: cadherin-18 ( 567) 2204 463.6 1e-129 XP_016864422 (OMIM: 603019) PREDICTED: cadherin-18 ( 567) 2204 463.6 1e-129 NP_001304157 (OMIM: 600562) cadherin-12 isoform 2 ( 754) 2198 462.5 3.1e-129 NP_001161139 (OMIM: 603019) cadherin-18 isoform 2 ( 574) 2097 441.6 4.4e-123 >>NP_001788 (OMIM: 600023) cadherin-11 isoform 1 preprop (796 aa) initn: 5314 init1: 5314 opt: 5314 Z-score: 5903.7 bits: 1103.2 E(85289): 0 Smith-Waterman score: 5314; 99.9% identity (100.0% similar) in 796 aa overlap (1-796:1-796) 10 20 30 40 50 60 pF1KB5 MKENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 FVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 RAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 MGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGEN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 GLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFIS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 NGPFKDTVTVKIAVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYS ::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 IDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 VNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 FTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 LLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 ITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 INTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 INTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFK 730 740 750 760 770 780 790 pF1KB5 KLADLYGSKDTFDDDS :::::::::::::::: NP_001 KLADLYGSKDTFDDDS 790 >>XP_011521105 (OMIM: 600023) PREDICTED: cadherin-11 iso (796 aa) initn: 5314 init1: 5314 opt: 5314 Z-score: 5903.7 bits: 1103.2 E(85289): 0 Smith-Waterman score: 5314; 99.9% identity (100.0% similar) in 796 aa overlap (1-796:1-796) 10 20 30 40 50 60 pF1KB5 MKENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 FVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 RAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 MGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGEN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 GLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFIS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 NGPFKDTVTVKIAVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYS ::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 IDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 VNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 FTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 LLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 ITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 INTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 INTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFK 730 740 750 760 770 780 790 pF1KB5 KLADLYGSKDTFDDDS :::::::::::::::: XP_011 KLADLYGSKDTFDDDS 790 >>XP_005255820 (OMIM: 600023) PREDICTED: cadherin-11 iso (796 aa) initn: 5314 init1: 5314 opt: 5314 Z-score: 5903.7 bits: 1103.2 E(85289): 0 Smith-Waterman score: 5314; 99.9% identity (100.0% similar) in 796 aa overlap (1-796:1-796) 10 20 30 40 50 60 pF1KB5 MKENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 FVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 RAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 MGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGEN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 GLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFIS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 NGPFKDTVTVKIAVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYS ::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 IDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 VNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 FTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 LLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 ITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 INTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 INTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFK 730 740 750 760 770 780 790 pF1KB5 KLADLYGSKDTFDDDS :::::::::::::::: XP_005 KLADLYGSKDTFDDDS 790 >>XP_005255819 (OMIM: 600023) PREDICTED: cadherin-11 iso (796 aa) initn: 5314 init1: 5314 opt: 5314 Z-score: 5903.7 bits: 1103.2 E(85289): 0 Smith-Waterman score: 5314; 99.9% identity (100.0% similar) in 796 aa overlap (1-796:1-796) 10 20 30 40 50 60 pF1KB5 MKENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 FVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 RAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 MGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGEN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 GLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFIS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 NGPFKDTVTVKIAVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYS ::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 IDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 VNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 FTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 LLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 ITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 INTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 INTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFK 730 740 750 760 770 780 790 pF1KB5 KLADLYGSKDTFDDDS :::::::::::::::: XP_005 KLADLYGSKDTFDDDS 790 >>XP_005255818 (OMIM: 600023) PREDICTED: cadherin-11 iso (796 aa) initn: 5314 init1: 5314 opt: 5314 Z-score: 5903.7 bits: 1103.2 E(85289): 0 Smith-Waterman score: 5314; 99.9% identity (100.0% similar) in 796 aa overlap (1-796:1-796) 10 20 30 40 50 60 pF1KB5 MKENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 FVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 RAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 MGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGEN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 GLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFIS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 NGPFKDTVTVKIAVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYS ::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 IDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 VNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 FTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 LLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 ITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 INTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 INTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFK 730 740 750 760 770 780 790 pF1KB5 KLADLYGSKDTFDDDS :::::::::::::::: XP_005 KLADLYGSKDTFDDDS 790 >>NP_001317505 (OMIM: 600023) cadherin-11 isoform 3 [Hom (670 aa) initn: 4436 init1: 4436 opt: 4436 Z-score: 4929.1 bits: 922.6 E(85289): 0 Smith-Waterman score: 4436; 99.9% identity (100.0% similar) in 670 aa overlap (127-796:1-670) 100 110 120 130 140 150 pF1KB5 AGTIFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNP :::::::::::::::::::::::::::::: NP_001 MAQAVDRDTNRPLEPPSEFIVKVQDINDNP 10 20 30 160 170 180 190 200 210 pF1KB5 PEFLHETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEFLHETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGI 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB5 IRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMS 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB5 VSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVD 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB5 FETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKIAVEDADEPPMFLAPSYIHEVQENA ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: NP_001 FETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENA 220 230 240 250 260 270 400 410 420 430 440 450 pF1KB5 AAGTVVGRVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAGTVVGRVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNI 280 290 300 310 320 330 460 470 480 490 500 510 pF1KB5 TVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISAD 340 350 360 370 380 390 520 530 540 550 560 570 pF1KB5 DKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISD 400 410 420 430 440 450 580 590 600 610 620 630 pF1KB5 GGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVL 460 470 480 490 500 510 640 650 660 670 680 690 pF1KB5 FVTLRRQKKEPLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVTLRRQKKEPLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDI 520 530 540 550 560 570 700 710 720 730 740 750 pF1KB5 KPEYQYMPRPGLRPAPNSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPEYQYMPRPGLRPAPNSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLS 580 590 600 610 620 630 760 770 780 790 pF1KB5 SLESATTDSDLDYDYLQNWGPRFKKLADLYGSKDTFDDDS :::::::::::::::::::::::::::::::::::::::: NP_001 SLESATTDSDLDYDYLQNWGPRFKKLADLYGSKDTFDDDS 640 650 660 670 >>NP_001295321 (OMIM: 600023) cadherin-11 isoform 2 prec (693 aa) initn: 4203 init1: 4203 opt: 4203 Z-score: 4669.9 bits: 874.7 E(85289): 0 Smith-Waterman score: 4203; 99.8% identity (100.0% similar) in 631 aa overlap (1-631:1-631) 10 20 30 40 50 60 pF1KB5 MKENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 FVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 RAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 MGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGEN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 GLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFIS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 NGPFKDTVTVKIAVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYS ::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 IDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 VNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 FTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 LLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENI ::::::::::::::::::::::::::::::: NP_001 LLSCNAEAYILNAGLSTGALIAILACIVILLGCPSLMEPPSPREDMRLLYLGFQLMLFSY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 ITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDF NP_001 VKVNRRFCLLGVFIKLPFLYVVATESPTTLTSL 670 680 690 >>NP_001787 (OMIM: 603008) cadherin-8 preproprotein [Hom (799 aa) initn: 3581 init1: 2175 opt: 3582 Z-score: 3978.9 bits: 747.1 E(85289): 6.9e-215 Smith-Waterman score: 3582; 69.4% identity (89.2% similar) in 751 aa overlap (42-790:50-796) 20 30 40 50 60 70 pF1KB5 VCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQFFVIEEYTGPDP :.: ..:.::::::::::.::.::..::.: NP_001 WITLPPCIYMAPMNQSQVLMSGSPLELNSLGEEQRILNRSKRGWVWNQMFVLEEFSGPEP 20 30 40 50 60 70 80 90 100 110 120 130 pF1KB5 VLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREERAQYTLMAQAV .::::::.:.: :. .:::::::.:::::: :.: .:.::: : :::::.:.::: :::: NP_001 ILVGRLHTDLDPGSKKIKYILSGDGAGTIFQINDVTGDIHAIKRLDREEKAEYTLTAQAV 80 90 100 110 120 130 140 150 160 170 180 190 pF1KB5 DRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQVTASDADDPTY : .:..:::::::::.:::::::: ::::. :::.::: : .:::: .:::.:::::.: NP_001 DWETSKPLEPPSEFIIKVQDINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDADDPVY 140 150 160 170 180 190 200 210 220 230 240 250 pF1KB5 GNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGT ::::::::::::::::::.: .:.::.:::::::::::::: ::::::::::: :::::: NP_001 GNSAKLVYSILEGQPYFSIEPETAIIKTALPNMDREAKEEYLVVIQAKDMGGHSGGLSGT 200 210 220 230 240 250 260 270 280 290 300 310 pF1KB5 TKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGD : .:.:::::::::::: ::.:..:: : .: : .:::::.: :::::. .:.:.::: NP_001 TTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAIGRVKANDQDIGENAQSSYDIIDGD 260 270 280 290 300 310 320 330 340 350 360 370 pF1KB5 GMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVK : ::::.: ..:.:.:.:.::.:::::..:.::::::::::::.: . ::::::.::: NP_001 GTALFEITSDAQAQDGIIRLRKPLDFETKKSYTLKVEAANVHIDPRFSGRGPFKDTATVK 320 330 340 350 360 370 380 390 400 410 420 430 pF1KB5 IAVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYSIDRHTDLDRFF :.::::::::.: .:.:. ::.:::: ..:.:.: :.::: ..::::.::::::::.: : NP_001 IVVEDADEPPVFSSPTYLLEVHENAALNSVIGQVTARDPDITSSPIRFSIDRHTDLERQF 380 390 400 410 420 430 440 450 460 470 480 490 pF1KB5 TINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAP .:: .:: : . ::::: ..: :::..:.::.:. : ..:::::.:::::::::.::. NP_001 NINADDGKITLATPLDRELSVWHNITIIATEIRNHSQISRVPVAIKVLDVNDNAPEFASE 440 450 460 470 480 490 500 510 520 530 540 550 pF1KB5 YEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTA ::.:.::. :: .: : :.:: :::: :: :..:: ::...:::::.. :.::. NP_001 YEAFLCENG--KP--GQVIQTVSAMDKDDPKNGHYFLYSLLPEMVNNPNFTIKKNEDNSL 500 510 520 530 540 550 560 570 580 590 600 610 pF1KB5 GVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYIL .. :...::.::::..:::::.:::.: ::.:::.::::.::::. .:.. :::.:::.: NP_001 SILAKHNGFNRQKQEVYLLPIIISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVEAYVL 560 570 580 590 600 610 620 630 640 650 660 670 pF1KB5 NAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENIITYDDEGGGEE ::: ::::::::::..:::::::::::::.:.::::. ..:::::::: ::::::::: NP_001 PIGLSMGALIAILACIILLLVIVVLFVTLRRHKNEPLIIKDDEDVRENIIRYDDEGGGEE 620 630 640 650 660 670 680 690 700 710 720 730 pF1KB5 DTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDFINTRIQEADND :::::::::::::::::::.:::::::. :.::: :: :.::.::::.:::.:..::::: NP_001 DTEAFDIATLQNPDGINGFLPRKDIKPDLQFMPRQGLAPVPNGVDVDEFINVRLHEADND 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 PTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFKKLADLY--GSK :::::::::::::::::::::::::::::.:.::: ..:::..::::::.:..:: : . NP_001 PTAPPYDSIQIYGYEGRGSVAGSLSSLESTTSDSDQNFDYLSDWGPRFKRLGELYSVGES 740 750 760 770 780 790 790 pF1KB5 DTFDDDS : NP_001 DKET >>XP_016864418 (OMIM: 603019) PREDICTED: cadherin-18 iso (790 aa) initn: 2546 init1: 1935 opt: 3100 Z-score: 3443.3 bits: 648.0 E(85289): 4.7e-185 Smith-Waterman score: 3100; 59.7% identity (82.1% similar) in 782 aa overlap (6-787:8-782) 10 20 30 40 50 pF1KB5 MKENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWN :. .:::: .. . .. : . .. . . .: .: : .: .: ::::::: XP_016 MKITSTSCICPVLVCLCFVQRCYGTAHHSSIKVMRN-QTKHIEG-ETEVHHRPKRGWVWN 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 QFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDR ::::.::. :::: ::.:::. :.:::..::::.::::::::.::: .:.::.::.::: XP_016 QFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGDIHSTKSLDR 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 EERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSV :....:.: :::.:: ::.:::: ::::.:::::::: :.: : ..::: :..:::: XP_016 EQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMSDMGTSV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 IQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQA .::::.:::::::::::..:::::.:::::::. .::.::::: ::::::.:.: ::::: XP_016 LQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAREHYSVVIQA 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 KDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIG :::.:..:::::.: :.:::::::::::.:::. ::. : :.: : ::..::.: : : XP_016 KDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 ENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKF :. .::.:..:::: : :.:: ::.::...::::...: :..:.:..:.::.:.: .: XP_016 SNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRF 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB5 ISNGPFKDTVTVKIAVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIR :::::.. .:: : :.::::.: :::. :: ::: ::::: : :.:::..:: .: XP_016 SHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQDPDSTNSLVR 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB5 YSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRV : :. ... ::::.:. . : :.::: :::::: : :::: :.:: : ..: :.::: XP_016 YFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPDLLSHVTVGIRV 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB5 LDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHN :::::: :..: :. ..::. .:: .: : :::: :::: :::::: : : .. : XP_016 LDVNDNPPELAREYDIIVCEN--SKP--GQVIHTISATDKDDFANGPRFNFFLDERLPVN 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB5 PNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVN ::::..::.::::.. .:: ::: ::.: :::.::::::: .::..::::.::.:. . XP_016 PNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERD 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB5 GALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRE : . .:.:::.. .:::::::::::: :..:::.:::::.::::.::::::. :::::: XP_016 GRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRSKKEPLII-SEEDVRE 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB5 NIITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVD :..:::::::::::::::::..:.::.. . . :.::.:: . :: . .:.::. XP_016 NVVTYDDEGGGEEDTEAFDITALRNPSAAEELKYRRDIRPEVKLTPRHQTSSTLESIDVQ 660 670 680 690 700 710 720 730 740 750 760 770 pF1KB5 DFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPR .::. :. ::: ::..:::::.: :.:::. : :::.:::.::::.:: :: :: .:::. XP_016 EFIKQRLAEADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQDYHYLGDWGPE 720 730 740 750 760 770 780 790 pF1KB5 FKKLADLYGSKDTFDDDS :::::.::: XP_016 FKKLAELYGEIESERTT 780 790 >>XP_016864419 (OMIM: 603019) PREDICTED: cadherin-18 iso (790 aa) initn: 2546 init1: 1935 opt: 3100 Z-score: 3443.3 bits: 648.0 E(85289): 4.7e-185 Smith-Waterman score: 3100; 59.7% identity (82.1% similar) in 782 aa overlap (6-787:8-782) 10 20 30 40 50 pF1KB5 MKENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWN :. .:::: .. . .. : . .. . . .: .: : .: .: ::::::: XP_016 MKITSTSCICPVLVCLCFVQRCYGTAHHSSIKVMRN-QTKHIEG-ETEVHHRPKRGWVWN 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 QFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDR ::::.::. :::: ::.:::. :.:::..::::.::::::::.::: .:.::.::.::: XP_016 QFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGDIHSTKSLDR 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 EERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSV :....:.: :::.:: ::.:::: ::::.:::::::: :.: : ..::: :..:::: XP_016 EQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMSDMGTSV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 IQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQA .::::.:::::::::::..:::::.:::::::. .::.::::: ::::::.:.: ::::: XP_016 LQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAREHYSVVIQA 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 KDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIG :::.:..:::::.: :.:::::::::::.:::. ::. : :.: : ::..::.: : : XP_016 KDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 ENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKF :. .::.:..:::: : :.:: ::.::...::::...: :..:.:..:.::.:.: .: XP_016 SNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRF 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB5 ISNGPFKDTVTVKIAVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIR :::::.. .:: : :.::::.: :::. :: ::: ::::: : :.:::..:: .: XP_016 SHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQDPDSTNSLVR 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB5 YSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRV : :. ... ::::.:. . : :.::: :::::: : :::: :.:: : ..: :.::: XP_016 YFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPDLLSHVTVGIRV 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB5 LDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHN :::::: :..: :. ..::. .:: .: : :::: :::: :::::: : : .. : XP_016 LDVNDNPPELAREYDIIVCEN--SKP--GQVIHTISATDKDDFANGPRFNFFLDERLPVN 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB5 PNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVN ::::..::.::::.. .:: ::: ::.: :::.::::::: .::..::::.::.:. . XP_016 PNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERD 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB5 GALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRE : . .:.:::.. .:::::::::::: :..:::.:::::.::::.::::::. :::::: XP_016 GRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRSKKEPLII-SEEDVRE 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB5 NIITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVD :..:::::::::::::::::..:.::.. . . :.::.:: . :: . .:.::. XP_016 NVVTYDDEGGGEEDTEAFDITALRNPSAAEELKYRRDIRPEVKLTPRHQTSSTLESIDVQ 660 670 680 690 700 710 720 730 740 750 760 770 pF1KB5 DFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPR .::. :. ::: ::..:::::.: :.:::. : :::.:::.::::.:: :: :: .:::. XP_016 EFIKQRLAEADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQDYHYLGDWGPE 720 730 740 750 760 770 780 790 pF1KB5 FKKLADLYGSKDTFDDDS :::::.::: XP_016 FKKLAELYGEIESERTT 780 790 796 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:20:58 2016 done: Thu Nov 3 22:21:00 2016 Total Scan time: 12.010 Total Display time: 0.270 Function used was FASTA [36.3.4 Apr, 2011]