Result of FASTA (omim) for pF1KB5147
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5147, 354 aa
  1>>>pF1KB5147 354 - 354 aa - 354 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1251+/-0.00036; mu= 16.9363+/- 0.022
 mean_var=62.6988+/-12.693, 0's: 0 Z-trim(113.2): 20  B-trim: 0 in 0/52
 Lambda= 0.161974
 statistics sampled from 22402 (22417) to 22402 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.263), width:  16
 Scan time:  8.200

The best scores are:                                      opt bits E(85289)
NP_001163 (OMIM: 107830) arginase-2, mitochondrial ( 354) 2340 555.5 6.3e-158
NP_000036 (OMIM: 207800,608313) arginase-1 isoform ( 322) 1336 320.9 2.5e-87
NP_001231367 (OMIM: 207800,608313) arginase-1 isof ( 330) 1317 316.4 5.5e-86
XP_011534103 (OMIM: 207800,608313) PREDICTED: argi ( 237)  540 134.8 1.9e-31


>>NP_001163 (OMIM: 107830) arginase-2, mitochondrial pre  (354 aa)
 initn: 2340 init1: 2340 opt: 2340  Z-score: 2956.2  bits: 555.5 E(85289): 6.3e-158
Smith-Waterman score: 2340; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:1-354)

               10        20        30        40        50        60
pF1KB5 MSLRGSLSRLLQTRVHSILKKSVHSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSLRGSLSRLLQTRVHSILKKSVHSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 LGCHLKDFGDLSFTPVPKDDLYNNLIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGCHLKDFGDLSFTPVPKDDLYNNLIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 SLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 FSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 KRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQ
              250       260       270       280       290       300

              310       320       330       340       350    
pF1KB5 LATSEEEAKTTANLAVDVIASSFGQTREGGHIVYDQLPTPSSPDESENQARVRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LATSEEEAKTTANLAVDVIASSFGQTREGGHIVYDQLPTPSSPDESENQARVRI
              310       320       330       340       350    

>>NP_000036 (OMIM: 207800,608313) arginase-1 isoform 2 [  (322 aa)
 initn: 1353 init1: 1110 opt: 1336  Z-score: 1688.9  bits: 320.9 E(85289): 2.5e-87
Smith-Waterman score: 1336; 60.1% identity (85.4% similar) in 316 aa overlap (25-340:7-321)

               10        20        30        40        50        60
pF1KB5 MSLRGSLSRLLQTRVHSILKKSVHSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSS
                               ....::::::.:: : :::.::...:.:::...:. 
NP_000                   MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKE
                                 10        20        30        40  

               70        80        90       100       110       120
pF1KB5 LGCHLKDFGDLSFTPVPKDDLYNNLIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDH
         : .::.::: :. .:.:. .. .. :::::: :...::  :... ..:   ..:::::
NP_000 QECDVKDYGDLPFADIPNDSPFQ-IVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDH
             50        60         70        80        90       100 

              130       140       150       160       170       180
pF1KB5 SLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPG
       :::::.::::::  ::: :.:::::.::::::::.:::::::::::::.::. :.:..::
NP_000 SLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPG
             110       120       130       140       150       160 

              190       200       210       220       230       240
pF1KB5 FSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIG
       :::. ::::. .::::::::::: ::.:::.  :.:::: ..::::: ::::.:.. :.:
NP_000 FSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLG
             170       180       190       200       210       220 

              250       260       270       280       290       300
pF1KB5 KRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQ
       ...::::::::.:..::...::::::::::::::::.::.:::..:::::.::..::::.
NP_000 RKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPS
             230       240       250       260       270       280 

              310       320       330       340       350    
pF1KB5 LATSEEEAKTTANLAVDVIASSFGQTREGGHIVYDQLPTPSSPDESENQARVRI
       :. . ::.  :.: :: .  . :: .:::.:   : :  :              
NP_000 LGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLNPPK             
             290       300       310       320               

>>NP_001231367 (OMIM: 207800,608313) arginase-1 isoform   (330 aa)
 initn: 1322 init1: 1110 opt: 1317  Z-score: 1664.7  bits: 316.4 E(85289): 5.5e-86
Smith-Waterman score: 1317; 59.0% identity (83.6% similar) in 324 aa overlap (25-340:7-329)

               10        20        30        40        50        60
pF1KB5 MSLRGSLSRLLQTRVHSILKKSVHSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSS
                               ....::::::.:: : :::.::...:.:::...:. 
NP_001                   MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKE
                                 10        20        30        40  

                       70        80        90       100       110  
pF1KB5 --------LGCHLKDFGDLSFTPVPKDDLYNNLIVNPRSVGLANQELAEVVSRAVSDGYS
               : : .::.::: :. .:.:. .. .. :::::: :...::  :... ..:  
NP_001 QVTQNFLILECDVKDYGDLPFADIPNDSPFQ-IVKNPRSVGKASEQLAGKVAEVKKNGRI
             50        60        70         80        90       100 

            120       130       140       150       160       170  
pF1KB5 CVTLGGDHSLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQ
        ..::::::::::.::::::  ::: :.:::::.::::::::.:::::::::::::.::.
NP_001 SLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELK
             110       120       130       140       150       160 

            180       190       200       210       220       230  
pF1KB5 DKVPQLPGFSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVME
        :.:..:::::. ::::. .::::::::::: ::.:::.  :.:::: ..::::: ::::
NP_001 GKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVME
             170       180       190       200       210       220 

            240       250       260       270       280       290  
pF1KB5 RTFDLLIGKRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSAL
       .:.. :.:...::::::::.:..::...::::::::::::::::.::.:::..:::::.:
NP_001 ETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGL
             230       240       250       260       270       280 

            300       310       320       330       340       350  
pF1KB5 DLVEVNPQLATSEEEAKTTANLAVDVIASSFGQTREGGHIVYDQLPTPSSPDESENQARV
       :..::::.:. . ::.  :.: :: .  . :: .:::.:   : :  :            
NP_001 DIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLNPPK           
             290       300       310       320       330           

         
pF1KB5 RI

>>XP_011534103 (OMIM: 207800,608313) PREDICTED: arginase  (237 aa)
 initn: 820 init1: 524 opt: 540  Z-score: 685.6  bits: 134.8 E(85289): 1.9e-31
Smith-Waterman score: 680; 39.2% identity (60.8% similar) in 316 aa overlap (25-340:7-236)

               10        20        30        40        50        60
pF1KB5 MSLRGSLSRLLQTRVHSILKKSVHSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSS
                               ....::::::.:: : :::.::...:.:::...:. 
XP_011                   MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKE
                                 10        20        30        40  

               70        80        90       100       110       120
pF1KB5 LGCHLKDFGDLSFTPVPKDDLYNNLIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDH
         : .::.::: :. .:.:. .. .. :::::: :...::  :... ..:   ..:::::
XP_011 QECDVKDYGDLPFADIPNDSPFQ-IVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDH
             50        60         70        80        90       100 

              130       140       150       160       170       180
pF1KB5 SLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPG
       :                                                           
XP_011 S-----------------------------------------------------------
                                                                   

              190       200       210       220       230       240
pF1KB5 FSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIG
                                 .:::.  :.:::: ..::::: ::::.:.. :.:
XP_011 --------------------------YILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLG
                                      110       120       130      

              250       260       270       280       290       300
pF1KB5 KRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQ
       ...::::::::.:..::...::::::::::::::::.::.:::..:::::.::..::::.
XP_011 RKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPS
        140       150       160       170       180       190      

              310       320       330       340       350    
pF1KB5 LATSEEEAKTTANLAVDVIASSFGQTREGGHIVYDQLPTPSSPDESENQARVRI
       :. . ::.  :.: :: .  . :: .:::.:   : :  :              
XP_011 LGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLNPPK             
        200       210       220       230                    




354 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 21:45:41 2016 done: Sat Nov  5 21:45:42 2016
 Total Scan time:  8.200 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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