FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5159, 196 aa 1>>>pF1KB5159 196 - 196 aa - 196 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2451+/-0.000858; mu= 13.6867+/- 0.052 mean_var=76.2000+/-15.203, 0's: 0 Z-trim(108.0): 184 B-trim: 301 in 1/49 Lambda= 0.146925 statistics sampled from 9721 (9935) to 9721 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.698), E-opt: 0.2 (0.305), width: 16 Scan time: 1.600 The best scores are: opt bits E(32554) CCDS1699.1 RHOB gene_id:388|Hs108|chr2 ( 196) 1324 289.7 8e-79 CCDS2795.1 RHOA gene_id:387|Hs108|chr3 ( 193) 1122 246.8 6.1e-66 CCDS854.1 RHOC gene_id:389|Hs108|chr1 ( 193) 1114 245.1 2e-65 CCDS82775.1 RHOA gene_id:387|Hs108|chr3 ( 187) 902 200.2 6.5e-52 CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 ( 192) 704 158.2 2.9e-39 CCDS33191.1 RHOQ gene_id:23433|Hs108|chr2 ( 205) 689 155.1 2.7e-38 CCDS11798.1 RAC3 gene_id:5881|Hs108|chr17 ( 192) 687 154.6 3.5e-38 CCDS13945.1 RAC2 gene_id:5880|Hs108|chr22 ( 192) 684 154.0 5.4e-38 CCDS7748.1 RHOG gene_id:391|Hs108|chr11 ( 191) 674 151.9 2.3e-37 CCDS221.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 661 149.1 1.6e-36 CCDS222.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 660 148.9 1.8e-36 CCDS8155.1 RHOD gene_id:29984|Hs108|chr11 ( 210) 659 148.7 2.3e-36 CCDS2190.1 RND3 gene_id:390|Hs108|chr2 ( 244) 643 145.4 2.7e-35 CCDS9757.1 RHOJ gene_id:57381|Hs108|chr14 ( 214) 622 140.9 5.3e-34 CCDS11452.1 RND2 gene_id:8153|Hs108|chr17 ( 227) 609 138.1 3.8e-33 CCDS9222.1 RHOF gene_id:54509|Hs108|chr12 ( 211) 604 137.1 7.4e-33 CCDS1575.1 RHOU gene_id:58480|Hs108|chr1 ( 258) 593 134.8 4.4e-32 CCDS10068.1 RHOV gene_id:171177|Hs108|chr15 ( 236) 552 126.1 1.7e-29 CCDS8771.1 RND1 gene_id:27289|Hs108|chr12 ( 232) 543 124.2 6.2e-29 CCDS3458.1 RHOH gene_id:399|Hs108|chr4 ( 191) 507 116.5 1.1e-26 CCDS5349.1 RAC1 gene_id:5879|Hs108|chr7 ( 211) 357 84.7 4.3e-17 CCDS82774.1 RHOA gene_id:387|Hs108|chr3 ( 90) 337 80.2 4.2e-16 CCDS6034.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 727) 332 79.8 4.4e-15 CCDS55211.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 734) 332 79.8 4.4e-15 CCDS55210.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 749) 332 79.8 4.5e-15 CCDS7261.1 RHOBTB1 gene_id:9886|Hs108|chr10 ( 696) 330 79.4 5.7e-15 CCDS31613.1 RAB1B gene_id:81876|Hs108|chr11 ( 201) 277 67.7 5.2e-12 CCDS14156.1 RAB9A gene_id:9367|Hs108|chrX ( 201) 275 67.3 7e-12 CCDS46306.1 RAB1A gene_id:5861|Hs108|chr2 ( 205) 275 67.3 7.1e-12 CCDS11703.1 RAB37 gene_id:326624|Hs108|chr17 ( 216) 272 66.7 1.2e-11 CCDS9003.1 RAB21 gene_id:23011|Hs108|chr12 ( 225) 271 66.5 1.4e-11 CCDS41846.1 RAB35 gene_id:11021|Hs108|chr12 ( 201) 269 66.0 1.7e-11 CCDS82198.1 RAB37 gene_id:326624|Hs108|chr17 ( 196) 268 65.8 1.9e-11 CCDS32722.1 RAB37 gene_id:326624|Hs108|chr17 ( 223) 268 65.9 2.1e-11 CCDS54161.1 RAB37 gene_id:326624|Hs108|chr17 ( 228) 268 65.9 2.2e-11 CCDS1058.1 RAB13 gene_id:5872|Hs108|chr1 ( 203) 267 65.6 2.3e-11 CCDS10183.1 RAB8B gene_id:51762|Hs108|chr15 ( 207) 267 65.6 2.3e-11 CCDS3747.1 RAB33B gene_id:83452|Hs108|chr4 ( 229) 267 65.7 2.5e-11 CCDS76691.1 RAB15 gene_id:376267|Hs108|chr14 ( 212) 266 65.4 2.8e-11 CCDS2131.1 RALB gene_id:5899|Hs108|chr2 ( 206) 265 65.2 3.1e-11 CCDS7698.1 HRAS gene_id:3265|Hs108|chr11 ( 189) 263 64.7 3.9e-11 CCDS5460.1 RALA gene_id:5898|Hs108|chr7 ( 206) 263 64.8 4.2e-11 CCDS14766.1 RAB39B gene_id:116442|Hs108|chrX ( 213) 262 64.6 5e-11 CCDS14515.1 RAB9B gene_id:51209|Hs108|chrX ( 201) 261 64.3 5.5e-11 CCDS12339.1 RAB8A gene_id:4218|Hs108|chr19 ( 207) 260 64.1 6.5e-11 CCDS10212.1 RAB11A gene_id:8766|Hs108|chr15 ( 216) 258 63.7 9e-11 >>CCDS1699.1 RHOB gene_id:388|Hs108|chr2 (196 aa) initn: 1324 init1: 1324 opt: 1324 Z-score: 1528.6 bits: 289.7 E(32554): 8e-79 Smith-Waterman score: 1324; 100.0% identity (100.0% similar) in 196 aa overlap (1-196:1-196) 10 20 30 40 50 60 pF1KB5 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ 130 140 150 160 170 180 190 pF1KB5 KRYGSQNGCINCCKVL :::::::::::::::: CCDS16 KRYGSQNGCINCCKVL 190 >>CCDS2795.1 RHOA gene_id:387|Hs108|chr3 (193 aa) initn: 1130 init1: 1110 opt: 1122 Z-score: 1297.3 bits: 246.8 E(32554): 6.1e-66 Smith-Waterman score: 1122; 85.3% identity (94.8% similar) in 191 aa overlap (1-190:1-191) 10 20 30 40 50 60 pF1KB5 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT :::::::::.::::::::::::::::::.::::::::::::::::::::::::::::::: CCDS27 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD :::::::::::::::::::::::::.:::::::::::::.:::::::::::::::.:::: CCDS27 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ ::.:::.: :::.::::::. ..:: :: :: :. :.:::::::.::::::: ::::::: CCDS27 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ 130 140 150 160 170 180 190 pF1KB5 KRYGSQ-NGCINCCKVL : :.. .::. CCDS27 ARRGKKKSGCLVL 190 >>CCDS854.1 RHOC gene_id:389|Hs108|chr1 (193 aa) initn: 1127 init1: 1107 opt: 1114 Z-score: 1288.1 bits: 245.1 E(32554): 2e-65 Smith-Waterman score: 1114; 85.8% identity (95.3% similar) in 190 aa overlap (1-189:1-190) 10 20 30 40 50 60 pF1KB5 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT :::::::::.::::::::::::::::::.:::::::::::::.::::::::::::::::: CCDS85 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD :::::::::::::::::::::::::.:::::::::::::.:::::::::::::::.:::: CCDS85 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ ::.:::.: :::.:::::::...:: :: ::.:. ::::::::::::::::: ::::.:: CCDS85 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ 130 140 150 160 170 180 190 pF1KB5 KRYGSQN-GCINCCKVL : ... :: CCDS85 VRKNKRRRGCPIL 190 >>CCDS82775.1 RHOA gene_id:387|Hs108|chr3 (187 aa) initn: 916 init1: 902 opt: 902 Z-score: 1045.4 bits: 200.2 E(32554): 6.5e-52 Smith-Waterman score: 902; 93.5% identity (99.3% similar) in 138 aa overlap (1-138:1-138) 10 20 30 40 50 60 pF1KB5 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT :::::::::.::::::::::::::::::.::::::::::::::::::::::::::::::: CCDS82 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD :::::::::::::::::::::::::.:::::::::::::.:::::::::::::::.:::: CCDS82 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ ::.:::.: :::.::::: CCDS82 LRNDEHTRRELAKMKQEPHCVARLECCGTILAQLQPPPPRFKRFPCLSLLSSWGYRRPLP 130 140 150 160 170 180 >>CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 (192 aa) initn: 727 init1: 698 opt: 704 Z-score: 818.5 bits: 158.2 E(32554): 2.9e-39 Smith-Waterman score: 704; 59.8% identity (78.2% similar) in 179 aa overlap (1-179:1-177) 10 20 30 40 50 60 pF1KB5 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT : :: : ::::::: ::::::: .. . :: :.::::.:: :.. :::: :.:.:::: CCDS53 MQAI--KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDT 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD :::::::::::::::.:::.:.:::. :: :.::. :: :::.: :::.:::::..: : CCDS53 AGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLD 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ ::.:. . .: . : :. .: ::: .: : :::::: :..:.. ::. : ::.: CCDS53 LRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLC 120 130 140 150 160 170 190 pF1KB5 KRYGSQNGCINCCKVL CCDS53 PPPVKKRKRKCLLL 180 190 >>CCDS33191.1 RHOQ gene_id:23433|Hs108|chr2 (205 aa) initn: 699 init1: 637 opt: 689 Z-score: 800.9 bits: 155.1 E(32554): 2.7e-38 Smith-Waterman score: 689; 52.0% identity (78.0% similar) in 200 aa overlap (3-195:7-204) 10 20 30 40 50 pF1KB5 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELA :. : ::::::: ::::::. ...: ::: ::::::..:.... : ::: :. CCDS33 MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 LWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVA :.::::::::::::::::: :::.:.:::: .: :..:. :.::::.:.. ::::..:.. CCDS33 LYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 NKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATR .. :::.: .. ..: ::..:. ...:. .: .: : :.:::: :..:.. ::. : CCDS33 TQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAII 130 140 150 160 170 180 180 190 pF1KB5 AAL-------QKRYGSQNGCINCCKVL : : .:: ::. ::::: . CCDS33 AILTPKKHTVKKRIGSR--CINCCLIT 190 200 >>CCDS11798.1 RAC3 gene_id:5881|Hs108|chr17 (192 aa) initn: 706 init1: 681 opt: 687 Z-score: 799.0 bits: 154.6 E(32554): 3.5e-38 Smith-Waterman score: 687; 58.1% identity (77.7% similar) in 179 aa overlap (1-179:1-177) 10 20 30 40 50 60 pF1KB5 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT : :: : ::::::: ::::::: .. . :: :.::::.:: :.. :::: :.:.:::: CCDS11 MQAI--KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDT 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD :::::::::::::::.:::.:.:::. :: :.::. :: :::.: ::..::.::..: : CCDS11 AGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLD 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ ::.:. . .: : :. .: ::: .: . :::::: :..:.. ::. : ::.: CCDS11 LRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLC 120 130 140 150 160 170 190 pF1KB5 KRYGSQNGCINCCKVL CCDS11 PPPVKKPGKKCTVF 180 190 >>CCDS13945.1 RAC2 gene_id:5880|Hs108|chr22 (192 aa) initn: 719 init1: 676 opt: 684 Z-score: 795.6 bits: 154.0 E(32554): 5.4e-38 Smith-Waterman score: 684; 55.0% identity (75.9% similar) in 191 aa overlap (1-189:1-189) 10 20 30 40 50 60 pF1KB5 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT : :: : ::::::: ::::::: .. . :: :.::::.:: :.. ::.: :.:.:::: CCDS13 MQAI--KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDT 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD :::::::::::::::.:::.:.:::. :: : ::. :: :::.: ::..:::::..: : CCDS13 AGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLD 60 70 80 90 100 110 130 140 150 160 170 pF1KB5 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAAL- ::.:. . .: . : :. .: :.: .:.. :::::: :..:.. ::. : ::.: CCDS13 LRDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLC 120 130 140 150 160 170 180 190 pF1KB5 -QKRYGSQNGCINCCKVL : .. .: CCDS13 PQPTRQQKRACSLL 180 190 >>CCDS7748.1 RHOG gene_id:391|Hs108|chr11 (191 aa) initn: 670 init1: 670 opt: 674 Z-score: 784.1 bits: 151.9 E(32554): 2.3e-37 Smith-Waterman score: 674; 56.6% identity (79.8% similar) in 173 aa overlap (7-179:5-177) 10 20 30 40 50 60 pF1KB5 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT : ::::::: ::::::: .. . ::. :.::::.:: :. :::. :.: :::: CCDS77 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDT 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD ::::.::::: ::::.:.:...:::. :: : ::. .:: ::: : ::.:::.::..::: CCDS77 AGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKD 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ ::.. . .: .. : :. ..:.:.: .:.: :::::: ..::.::: :.::.: CCDS77 LRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLN 120 130 140 150 160 170 190 pF1KB5 KRYGSQNGCINCCKVL CCDS77 PTPIKRGRSCILL 180 190 >>CCDS221.1 CDC42 gene_id:998|Hs108|chr1 (191 aa) initn: 676 init1: 657 opt: 661 Z-score: 769.2 bits: 149.1 E(32554): 1.6e-36 Smith-Waterman score: 661; 54.0% identity (80.5% similar) in 174 aa overlap (7-180:5-178) 10 20 30 40 50 60 pF1KB5 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT : ::::::: ::::::: .. ..:: ::::::.::.. . . :. :.:.:: CCDS22 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDT 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD :::::::::::::::.:::.:.:::: ::.:.::. ::::::. : ::..:..::... : CCDS22 AGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQID 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ ::.: . .::. ::.:. . .. .: ..: :.:::: :..:...::. : :::. CCDS22 LRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALE 120 130 140 150 160 170 190 pF1KB5 KRYGSQNGCINCCKVL CCDS22 PPEPKKSRRCVLL 180 190 196 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 16:13:36 2016 done: Thu Nov 3 16:13:36 2016 Total Scan time: 1.600 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]