FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5161, 463 aa 1>>>pF1KB5161 463 - 463 aa - 463 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6829+/-0.00108; mu= 15.5912+/- 0.065 mean_var=64.7146+/-13.065, 0's: 0 Z-trim(103.3): 19 B-trim: 167 in 1/47 Lambda= 0.159431 statistics sampled from 7337 (7343) to 7337 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.584), E-opt: 0.2 (0.226), width: 16 Scan time: 2.880 The best scores are: opt bits E(32554) CCDS9406.1 SUCLA2 gene_id:8803|Hs108|chr13 ( 463) 2968 691.8 4e-199 CCDS43104.1 SUCLG2 gene_id:8801|Hs108|chr3 ( 432) 1357 321.2 1.3e-87 CCDS54605.1 SUCLG2 gene_id:8801|Hs108|chr3 ( 440) 1290 305.8 5.9e-83 >>CCDS9406.1 SUCLA2 gene_id:8803|Hs108|chr13 (463 aa) initn: 2968 init1: 2968 opt: 2968 Z-score: 3688.3 bits: 691.8 E(32554): 4e-199 Smith-Waterman score: 2968; 99.8% identity (100.0% similar) in 463 aa overlap (1-463:1-463) 10 20 30 40 50 60 pF1KB5 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGLFNNHGLQVQQQQQRNLSLHEYMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS94 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGLFNNHGLQVQQQQQRNLSLHEYMS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLKGGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS94 MELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLKGGVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 IVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS94 IVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQGP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESAAENM ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: CCDS94 VLIGSSHGGVNIEDVAAESPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESAAENM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS94 VKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDER 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS94 DKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 FKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDAKALI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS94 FKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDAKALI 370 380 390 400 410 420 430 440 450 460 pF1KB5 ADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI ::::::::::::::::::::::::::::::::::::::::::: CCDS94 ADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI 430 440 450 460 >>CCDS43104.1 SUCLG2 gene_id:8801|Hs108|chr3 (432 aa) initn: 1377 init1: 1354 opt: 1357 Z-score: 1686.2 bits: 321.2 E(32554): 1.3e-87 Smith-Waterman score: 1357; 52.0% identity (78.6% similar) in 425 aa overlap (21-441:4-426) 10 20 30 40 50 pF1KB5 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGL---FNNHGLQ-VQQQQQRNLSLH : .:: :...: . .: : : : :: ..: :.:. CCDS43 MASPVAAQ--AGKLLRALALRPRFLAAGSQAVQLTSRRWLNLQ 10 20 30 40 60 70 80 90 100 110 pF1KB5 EYMSMELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLK ::.: .:... :: : . .:: . .:: ::.:..:..:.:::.::::::::.:.:::: CCDS43 EYQSKKLMSDNGVRVQRFFVADTANEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLK 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB5 GGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERS :::... .:. . ...:::: .: :::: ..: :.:.: : :: :.:: :.:: CCDS43 GGVHLTKDPNVVGQLAKQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRS 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB5 FQGPVLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESA .::::.:: .:::.::.::: .:: :.:: ::: :::: :: ..:...:: . .: CCDS43 CNGPVLVGSPQGGVDIEEVAASNPELIFKEQIDIFEGIKDSQAQRMAENLGFVGPLKSQA 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB5 AENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQ :....:::.:::: :::..:.::. : .: :.:.:::::::.:. .::: :: ..: .. CCDS43 ADQITKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSE 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB5 EDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQ .. ...::: .:.::::::::.:.:::::::::: ::: :.:: ::::::.:::. : CCDS43 NEPIENEAAKYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQ 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB5 VTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDA : .::::.:.: :: ::::::::::. : .::.::. : ..::.:.:.::::.:: :..: CCDS43 VYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTNVQEA 350 360 370 380 390 400 420 430 440 450 460 pF1KB5 KALIADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI . .. .::: : . ::..::. .: CCDS43 QKILNNSGLPITSAIDLEDAAKKAVASVAKK 410 420 430 >>CCDS54605.1 SUCLG2 gene_id:8801|Hs108|chr3 (440 aa) initn: 1287 init1: 1287 opt: 1290 Z-score: 1602.8 bits: 305.8 E(32554): 5.9e-83 Smith-Waterman score: 1290; 53.2% identity (79.0% similar) in 395 aa overlap (21-411:4-396) 10 20 30 40 50 pF1KB5 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGL---FNNHGLQ-VQQQQQRNLSLH : .:: :...: . .: : : : :: ..: :.:. CCDS54 MASPVAAQ--AGKLLRALALRPRFLAAGSQAVQLTSRRWLNLQ 10 20 30 40 60 70 80 90 100 110 pF1KB5 EYMSMELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLK ::.: .:... :: : . .:: . .:: ::.:..:..:.:::.::::::::.:.:::: CCDS54 EYQSKKLMSDNGVRVQRFFVADTANEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLK 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB5 GGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERS :::... .:. . ...:::: .: :::: ..: :.:.: : :: :.:: :.:: CCDS54 GGVHLTKDPNVVGQLAKQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRS 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB5 FQGPVLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESA .::::.:: .:::.::.::: .:: :.:: ::: :::: :: ..:...:: . .: CCDS54 CNGPVLVGSPQGGVDIEEVAASNPELIFKEQIDIFEGIKDSQAQRMAENLGFVGPLKSQA 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB5 AENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQ :....:::.:::: :::..:.::. : .: :.:.:::::::.:. .::: :: ..: .. CCDS54 ADQITKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSE 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB5 EDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQ .. ...::: .:.::::::::.:.:::::::::: ::: :.:: ::::::.:::. : CCDS54 NEPIENEAAKYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQ 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB5 VTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDA : .::::.:.: :: ::::::::::. : .::.::. : ..::.:.:.::::.:: CCDS54 VYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTFMEKK 350 360 370 380 390 400 420 430 440 450 460 pF1KB5 KALIADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI CCDS54 GSYMHIKQETGNSNENITGIQENVAHQNLSKCAISIFLC 410 420 430 440 463 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:21:59 2016 done: Sat Nov 5 06:22:00 2016 Total Scan time: 2.880 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]