Result of FASTA (omim) for pF1KB5161
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5161, 463 aa
  1>>>pF1KB5161 463 - 463 aa - 463 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5544+/-0.000466; mu= 16.3241+/- 0.029
 mean_var=64.0712+/-13.101, 0's: 0 Z-trim(109.6): 20  B-trim: 254 in 1/49
 Lambda= 0.160230
 statistics sampled from 17755 (17772) to 17755 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.563), E-opt: 0.2 (0.208), width:  16
 Scan time:  9.050

The best scores are:                                      opt bits E(85289)
NP_003841 (OMIM: 603921,612073) succinate--CoA lig ( 463) 2968 695.2 9.4e-200
XP_016876295 (OMIM: 603921,612073) PREDICTED: succ ( 405) 2593 608.5  1e-173
XP_016876296 (OMIM: 603921,612073) PREDICTED: succ ( 384) 2396 563.0 5.1e-160
XP_016876298 (OMIM: 603921,612073) PREDICTED: succ ( 329) 2122 499.6 5.2e-141
XP_016876297 (OMIM: 603921,612073) PREDICTED: succ ( 344) 1709 404.2 2.9e-112
NP_003839 (OMIM: 603922) succinate--CoA ligase [GD ( 432) 1357 322.8 1.1e-87
XP_016862908 (OMIM: 603922) PREDICTED: succinyl-Co ( 433) 1290 307.3 5.2e-83
NP_001171070 (OMIM: 603922) succinate--CoA ligase  ( 440) 1290 307.3 5.3e-83
XP_016862907 (OMIM: 603922) PREDICTED: succinyl-Co ( 445) 1290 307.3 5.3e-83
XP_016862906 (OMIM: 603922) PREDICTED: succinyl-Co ( 457) 1290 307.3 5.4e-83
XP_016862905 (OMIM: 603922) PREDICTED: succinyl-Co ( 458) 1290 307.3 5.4e-83
XP_016862904 (OMIM: 603922) PREDICTED: succinyl-Co ( 480) 1290 307.4 5.7e-83
XP_016862909 (OMIM: 603922) PREDICTED: succinyl-Co ( 408) 1285 306.2 1.1e-82


>>NP_003841 (OMIM: 603921,612073) succinate--CoA ligase   (463 aa)
 initn: 2968 init1: 2968 opt: 2968  Z-score: 3707.2  bits: 695.2 E(85289): 9.4e-200
Smith-Waterman score: 2968; 99.8% identity (100.0% similar) in 463 aa overlap (1-463:1-463)

               10        20        30        40        50        60
pF1KB5 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGLFNNHGLQVQQQQQRNLSLHEYMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGLFNNHGLQVQQQQQRNLSLHEYMS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 MELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLKGGVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLKGGVK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 IVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQGP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 VLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESAAENM
       ::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
NP_003 VLIGSSHGGVNIEDVAAESPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESAAENM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 VKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDER
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 DKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 FKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDAKALI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDAKALI
              370       380       390       400       410       420

              430       440       450       460   
pF1KB5 ADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
       :::::::::::::::::::::::::::::::::::::::::::
NP_003 ADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
              430       440       450       460   

>>XP_016876295 (OMIM: 603921,612073) PREDICTED: succinyl  (405 aa)
 initn: 2593 init1: 2593 opt: 2593  Z-score: 3239.6  bits: 608.5 E(85289): 1e-173
Smith-Waterman score: 2593; 99.8% identity (100.0% similar) in 405 aa overlap (59-463:1-405)

       30        40        50        60        70        80        
pF1KB5 AQVLGSSGLFNNHGLQVQQQQQRNLSLHEYMSMELLQEAGVSVPKGYVAKSPDEAYAIAK
                                     ::::::::::::::::::::::::::::::
XP_016                               MSMELLQEAGVSVPKGYVAKSPDEAYAIAK
                                             10        20        30

       90       100       110       120       130       140        
pF1KB5 KLGSKDVVIKAQVLAGGRGKGTFESGLKGGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLGSKDVVIKAQVLAGGRGKGTFESGLKGGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEK
               40        50        60        70        80        90

      150       160       170       180       190       200        
pF1KB5 GRICNQVLVCERKYPRREYYFAITMERSFQGPVLIGSSHGGVNIEDVAAETPEAIIKEPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
XP_016 GRICNQVLVCERKYPRREYYFAITMERSFQGPVLIGSSHGGVNIEDVAAESPEAIIKEPI
              100       110       120       130       140       150

      210       220       230       240       250       260        
pF1KB5 DIEEGIKKEQALQLAQKMGFPPNIVESAAENMVKLYSLFLKYDATMIEINPMVEDSDGAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIEEGIKKEQALQLAQKMGFPPNIVESAAENMVKLYSLFLKYDATMIEINPMVEDSDGAV
              160       170       180       190       200       210

      270       280       290       300       310       320        
pF1KB5 LCMDAKINFDSNSAYRQKKIFDLQDWTQEDERDKDAAKANLNYIGLDGNIGCLVNGAGLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCMDAKINFDSNSAYRQKKIFDLQDWTQEDERDKDAAKANLNYIGLDGNIGCLVNGAGLA
              220       230       240       250       260       270

      330       340       350       360       370       380        
pF1KB5 MATMDIIKLHGGTPANFLDVGGGATVHQVTEAFKLITSDKKVLAILVNIFGGIMRCDVIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MATMDIIKLHGGTPANFLDVGGGATVHQVTEAFKLITSDKKVLAILVNIFGGIMRCDVIA
              280       290       300       310       320       330

      390       400       410       420       430       440        
pF1KB5 QGIVMAVKDLEIKIPVVVRLQGTRVDDAKALIADSGLKILACDDLDEAARMVVKLSEIVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGIVMAVKDLEIKIPVVVRLQGTRVDDAKALIADSGLKILACDDLDEAARMVVKLSEIVT
              340       350       360       370       380       390

      450       460   
pF1KB5 LAKQAHVDVKFQLPI
       :::::::::::::::
XP_016 LAKQAHVDVKFQLPI
              400     

>>XP_016876296 (OMIM: 603921,612073) PREDICTED: succinyl  (384 aa)
 initn: 2396 init1: 2396 opt: 2396  Z-score: 2993.9  bits: 563.0 E(85289): 5.1e-160
Smith-Waterman score: 2396; 99.5% identity (100.0% similar) in 374 aa overlap (90-463:11-384)

      60        70        80        90       100       110         
pF1KB5 SMELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLKGGV
                                     .:::::::::::::::::::::::::::::
XP_016                     MMNSMAERSVVGSKDVVIKAQVLAGGRGKGTFESGLKGGV
                                   10        20        30        40

     120       130       140       150       160       170         
pF1KB5 KIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQG
               50        60        70        80        90       100

     180       190       200       210       220       230         
pF1KB5 PVLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESAAEN
       :::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_016 PVLIGSSHGGVNIEDVAAESPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESAAEN
              110       120       130       140       150       160

     240       250       260       270       280       290         
pF1KB5 MVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDE
              170       180       190       200       210       220

     300       310       320       330       340       350         
pF1KB5 RDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTE
              230       240       250       260       270       280

     360       370       380       390       400       410         
pF1KB5 AFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDAKAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDAKAL
              290       300       310       320       330       340

     420       430       440       450       460   
pF1KB5 IADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
       ::::::::::::::::::::::::::::::::::::::::::::
XP_016 IADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
              350       360       370       380    

>>XP_016876298 (OMIM: 603921,612073) PREDICTED: succinyl  (329 aa)
 initn: 2122 init1: 2122 opt: 2122  Z-score: 2652.6  bits: 499.6 E(85289): 5.2e-141
Smith-Waterman score: 2122; 99.7% identity (100.0% similar) in 329 aa overlap (135-463:1-329)

          110       120       130       140       150       160    
pF1KB5 GRGKGTFESGLKGGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPR
                                     ::::::::::::::::::::::::::::::
XP_016                               MIGKKLFTKQTGEKGRICNQVLVCERKYPR
                                             10        20        30

          170       180       190       200       210       220    
pF1KB5 REYYFAITMERSFQGPVLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQ
       ::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
XP_016 REYYFAITMERSFQGPVLIGSSHGGVNIEDVAAESPEAIIKEPIDIEEGIKKEQALQLAQ
               40        50        60        70        80        90

          230       240       250       260       270       280    
pF1KB5 KMGFPPNIVESAAENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMGFPPNIVESAAENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYR
              100       110       120       130       140       150

          290       300       310       320       330       340    
pF1KB5 QKKIFDLQDWTQEDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKKIFDLQDWTQEDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPAN
              160       170       180       190       200       210

          350       360       370       380       390       400    
pF1KB5 FLDVGGGATVHQVTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLDVGGGATVHQVTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPV
              220       230       240       250       260       270

          410       420       430       440       450       460   
pF1KB5 VVRLQGTRVDDAKALIADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVRLQGTRVDDAKALIADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
              280       290       300       310       320         

>>XP_016876297 (OMIM: 603921,612073) PREDICTED: succinyl  (344 aa)
 initn: 1709 init1: 1709 opt: 1709  Z-score: 2136.4  bits: 404.2 E(85289): 2.9e-112
Smith-Waterman score: 1709; 99.6% identity (100.0% similar) in 267 aa overlap (1-267:1-267)

               10        20        30        40        50        60
pF1KB5 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGLFNNHGLQVQQQQQRNLSLHEYMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGLFNNHGLQVQQQQQRNLSLHEYMS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 MELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLKGGVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLKGGVK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 IVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQGP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 VLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESAAENM
       ::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
XP_016 VLIGSSHGGVNIEDVAAESPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESAAENM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 VKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDER
       :::::::::::::::::::::::::::                                 
XP_016 VKLYSLFLKYDATMIEINPMVEDSDGAGPPGSHIELSCHIHLTWNRSGSLIYFLTLFFVV
              250       260       270       280       290       300

>>NP_003839 (OMIM: 603922) succinate--CoA ligase [GDP-fo  (432 aa)
 initn: 1377 init1: 1354 opt: 1357  Z-score: 1695.0  bits: 322.8 E(85289): 1.1e-87
Smith-Waterman score: 1357; 52.0% identity (78.6% similar) in 425 aa overlap (21-441:4-426)

               10        20        30           40         50      
pF1KB5 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGL---FNNHGLQ-VQQQQQRNLSLH
                           : .::  :...: . .:   :   : : ::  ..: :.:.
NP_003                  MASPVAAQ--AGKLLRALALRPRFLAAGSQAVQLTSRRWLNLQ
                                  10        20        30        40 

         60        70        80        90       100       110      
pF1KB5 EYMSMELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLK
       ::.: .:... :: : . .:: . .::   ::.:..:..:.:::.::::::::.:.::::
NP_003 EYQSKKLMSDNGVRVQRFFVADTANEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLK
              50        60        70        80        90       100 

        120       130       140       150       160       170      
pF1KB5 GGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERS
       :::... .:. .  ...:::: .: :::: ..:   :.:.: :     :: :.:: :.::
NP_003 GGVHLTKDPNVVGQLAKQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRS
             110       120       130       140       150       160 

        180       190       200       210       220       230      
pF1KB5 FQGPVLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESA
        .::::.:: .:::.::.::: .:: :.:: ::: ::::  :: ..:...::   .  .:
NP_003 CNGPVLVGSPQGGVDIEEVAASNPELIFKEQIDIFEGIKDSQAQRMAENLGFVGPLKSQA
             170       180       190       200       210       220 

        240       250       260       270       280       290      
pF1KB5 AENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQ
       :....:::.:::: :::..:.::. :  .: :.:.:::::::.:. .::: :: ..: ..
NP_003 ADQITKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSE
             230       240       250       260       270       280 

        300       310       320       330       340       350      
pF1KB5 EDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQ
       ..  ...::: .:.::::::::.:.:::::::::: ::: :.:: ::::::.:::.   :
NP_003 NEPIENEAAKYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQ
             290       300       310       320       330       340 

        360       370       380       390       400       410      
pF1KB5 VTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDA
       : .::::.:.: :: ::::::::::. : .::.::. : ..::.:.:.::::.:: :..:
NP_003 VYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTNVQEA
             350       360       370       380       390       400 

        420       430       440       450       460   
pF1KB5 KALIADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
       . .. .::: : .  ::..::. .:                      
NP_003 QKILNNSGLPITSAIDLEDAAKKAVASVAKK                
             410       420       430                  

>>XP_016862908 (OMIM: 603922) PREDICTED: succinyl-CoA li  (433 aa)
 initn: 1287 init1: 1287 opt: 1290  Z-score: 1611.3  bits: 307.3 E(85289): 5.2e-83
Smith-Waterman score: 1290; 53.2% identity (79.0% similar) in 395 aa overlap (21-411:4-396)

               10        20        30           40         50      
pF1KB5 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGL---FNNHGLQ-VQQQQQRNLSLH
                           : .::  :...: . .:   :   : : ::  ..: :.:.
XP_016                  MASPVAAQ--AGKLLRALALRPRFLAAGSQAVQLTSRRWLNLQ
                                  10        20        30        40 

         60        70        80        90       100       110      
pF1KB5 EYMSMELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLK
       ::.: .:... :: : . .:: . .::   ::.:..:..:.:::.::::::::.:.::::
XP_016 EYQSKKLMSDNGVRVQRFFVADTANEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLK
              50        60        70        80        90       100 

        120       130       140       150       160       170      
pF1KB5 GGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERS
       :::... .:. .  ...:::: .: :::: ..:   :.:.: :     :: :.:: :.::
XP_016 GGVHLTKDPNVVGQLAKQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRS
             110       120       130       140       150       160 

        180       190       200       210       220       230      
pF1KB5 FQGPVLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESA
        .::::.:: .:::.::.::: .:: :.:: ::: ::::  :: ..:...::   .  .:
XP_016 CNGPVLVGSPQGGVDIEEVAASNPELIFKEQIDIFEGIKDSQAQRMAENLGFVGPLKSQA
             170       180       190       200       210       220 

        240       250       260       270       280       290      
pF1KB5 AENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQ
       :....:::.:::: :::..:.::. :  .: :.:.:::::::.:. .::: :: ..: ..
XP_016 ADQITKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSE
             230       240       250       260       270       280 

        300       310       320       330       340       350      
pF1KB5 EDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQ
       ..  ...::: .:.::::::::.:.:::::::::: ::: :.:: ::::::.:::.   :
XP_016 NEPIENEAAKYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQ
             290       300       310       320       330       340 

        360       370       380       390       400       410      
pF1KB5 VTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDA
       : .::::.:.: :: ::::::::::. : .::.::. : ..::.:.:.::::.::     
XP_016 VYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTFMEKK
             350       360       370       380       390       400 

        420       430       440       450       460   
pF1KB5 KALIADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
                                                      
XP_016 GSYMHIKQETGNSNENITGIQENVAHQNLRLN               
             410       420       430                  

>>NP_001171070 (OMIM: 603922) succinate--CoA ligase [GDP  (440 aa)
 initn: 1287 init1: 1287 opt: 1290  Z-score: 1611.2  bits: 307.3 E(85289): 5.3e-83
Smith-Waterman score: 1290; 53.2% identity (79.0% similar) in 395 aa overlap (21-411:4-396)

               10        20        30           40         50      
pF1KB5 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGL---FNNHGLQ-VQQQQQRNLSLH
                           : .::  :...: . .:   :   : : ::  ..: :.:.
NP_001                  MASPVAAQ--AGKLLRALALRPRFLAAGSQAVQLTSRRWLNLQ
                                  10        20        30        40 

         60        70        80        90       100       110      
pF1KB5 EYMSMELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLK
       ::.: .:... :: : . .:: . .::   ::.:..:..:.:::.::::::::.:.::::
NP_001 EYQSKKLMSDNGVRVQRFFVADTANEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLK
              50        60        70        80        90       100 

        120       130       140       150       160       170      
pF1KB5 GGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERS
       :::... .:. .  ...:::: .: :::: ..:   :.:.: :     :: :.:: :.::
NP_001 GGVHLTKDPNVVGQLAKQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRS
             110       120       130       140       150       160 

        180       190       200       210       220       230      
pF1KB5 FQGPVLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESA
        .::::.:: .:::.::.::: .:: :.:: ::: ::::  :: ..:...::   .  .:
NP_001 CNGPVLVGSPQGGVDIEEVAASNPELIFKEQIDIFEGIKDSQAQRMAENLGFVGPLKSQA
             170       180       190       200       210       220 

        240       250       260       270       280       290      
pF1KB5 AENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQ
       :....:::.:::: :::..:.::. :  .: :.:.:::::::.:. .::: :: ..: ..
NP_001 ADQITKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSE
             230       240       250       260       270       280 

        300       310       320       330       340       350      
pF1KB5 EDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQ
       ..  ...::: .:.::::::::.:.:::::::::: ::: :.:: ::::::.:::.   :
NP_001 NEPIENEAAKYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQ
             290       300       310       320       330       340 

        360       370       380       390       400       410      
pF1KB5 VTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDA
       : .::::.:.: :: ::::::::::. : .::.::. : ..::.:.:.::::.::     
NP_001 VYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTFMEKK
             350       360       370       380       390       400 

        420       430       440       450       460   
pF1KB5 KALIADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
                                                      
NP_001 GSYMHIKQETGNSNENITGIQENVAHQNLSKCAISIFLC        
             410       420       430       440        

>>XP_016862907 (OMIM: 603922) PREDICTED: succinyl-CoA li  (445 aa)
 initn: 1287 init1: 1287 opt: 1290  Z-score: 1611.1  bits: 307.3 E(85289): 5.3e-83
Smith-Waterman score: 1290; 53.2% identity (79.0% similar) in 395 aa overlap (21-411:4-396)

               10        20        30           40         50      
pF1KB5 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGL---FNNHGLQ-VQQQQQRNLSLH
                           : .::  :...: . .:   :   : : ::  ..: :.:.
XP_016                  MASPVAAQ--AGKLLRALALRPRFLAAGSQAVQLTSRRWLNLQ
                                  10        20        30        40 

         60        70        80        90       100       110      
pF1KB5 EYMSMELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLK
       ::.: .:... :: : . .:: . .::   ::.:..:..:.:::.::::::::.:.::::
XP_016 EYQSKKLMSDNGVRVQRFFVADTANEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLK
              50        60        70        80        90       100 

        120       130       140       150       160       170      
pF1KB5 GGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERS
       :::... .:. .  ...:::: .: :::: ..:   :.:.: :     :: :.:: :.::
XP_016 GGVHLTKDPNVVGQLAKQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRS
             110       120       130       140       150       160 

        180       190       200       210       220       230      
pF1KB5 FQGPVLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESA
        .::::.:: .:::.::.::: .:: :.:: ::: ::::  :: ..:...::   .  .:
XP_016 CNGPVLVGSPQGGVDIEEVAASNPELIFKEQIDIFEGIKDSQAQRMAENLGFVGPLKSQA
             170       180       190       200       210       220 

        240       250       260       270       280       290      
pF1KB5 AENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQ
       :....:::.:::: :::..:.::. :  .: :.:.:::::::.:. .::: :: ..: ..
XP_016 ADQITKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSE
             230       240       250       260       270       280 

        300       310       320       330       340       350      
pF1KB5 EDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQ
       ..  ...::: .:.::::::::.:.:::::::::: ::: :.:: ::::::.:::.   :
XP_016 NEPIENEAAKYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQ
             290       300       310       320       330       340 

        360       370       380       390       400       410      
pF1KB5 VTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDA
       : .::::.:.: :: ::::::::::. : .::.::. : ..::.:.:.::::.::     
XP_016 VYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTFMEKK
             350       360       370       380       390       400 

        420       430       440       450       460   
pF1KB5 KALIADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
                                                      
XP_016 GSYMHIKQETGNSNENITGIQENVAHQNLIEKDIHIQTYGITGL   
             410       420       430       440        

>>XP_016862906 (OMIM: 603922) PREDICTED: succinyl-CoA li  (457 aa)
 initn: 1287 init1: 1287 opt: 1290  Z-score: 1610.9  bits: 307.3 E(85289): 5.4e-83
Smith-Waterman score: 1290; 53.2% identity (79.0% similar) in 395 aa overlap (21-411:4-396)

               10        20        30           40         50      
pF1KB5 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGL---FNNHGLQ-VQQQQQRNLSLH
                           : .::  :...: . .:   :   : : ::  ..: :.:.
XP_016                  MASPVAAQ--AGKLLRALALRPRFLAAGSQAVQLTSRRWLNLQ
                                  10        20        30        40 

         60        70        80        90       100       110      
pF1KB5 EYMSMELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLK
       ::.: .:... :: : . .:: . .::   ::.:..:..:.:::.::::::::.:.::::
XP_016 EYQSKKLMSDNGVRVQRFFVADTANEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLK
              50        60        70        80        90       100 

        120       130       140       150       160       170      
pF1KB5 GGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERS
       :::... .:. .  ...:::: .: :::: ..:   :.:.: :     :: :.:: :.::
XP_016 GGVHLTKDPNVVGQLAKQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRS
             110       120       130       140       150       160 

        180       190       200       210       220       230      
pF1KB5 FQGPVLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESA
        .::::.:: .:::.::.::: .:: :.:: ::: ::::  :: ..:...::   .  .:
XP_016 CNGPVLVGSPQGGVDIEEVAASNPELIFKEQIDIFEGIKDSQAQRMAENLGFVGPLKSQA
             170       180       190       200       210       220 

        240       250       260       270       280       290      
pF1KB5 AENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQ
       :....:::.:::: :::..:.::. :  .: :.:.:::::::.:. .::: :: ..: ..
XP_016 ADQITKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSE
             230       240       250       260       270       280 

        300       310       320       330       340       350      
pF1KB5 EDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQ
       ..  ...::: .:.::::::::.:.:::::::::: ::: :.:: ::::::.:::.   :
XP_016 NEPIENEAAKYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQ
             290       300       310       320       330       340 

        360       370       380       390       400       410      
pF1KB5 VTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDA
       : .::::.:.: :: ::::::::::. : .::.::. : ..::.:.:.::::.::     
XP_016 VYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTFMEKK
             350       360       370       380       390       400 

        420       430       440       450       460            
pF1KB5 KALIADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI         
                                                               
XP_016 GSYMHIKQETGNSNENITGIQENVAHQNLTCPHHLKPQPQLHLSNRYFQTLLEDKA
             410       420       430       440       450       




463 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 06:22:00 2016 done: Sat Nov  5 06:22:01 2016
 Total Scan time:  9.050 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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