FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5164, 427 aa 1>>>pF1KB5164 427 - 427 aa - 427 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.1428+/-0.000329; mu= 4.6904+/- 0.020 mean_var=169.0757+/-33.971, 0's: 0 Z-trim(120.7): 49 B-trim: 0 in 0/58 Lambda= 0.098636 statistics sampled from 36186 (36235) to 36186 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.768), E-opt: 0.2 (0.425), width: 16 Scan time: 9.110 The best scores are: opt bits E(85289) NP_001562 (OMIM: 603734,616532) interferon regulat ( 427) 3028 442.7 8.2e-124 XP_016882256 (OMIM: 603734,616532) PREDICTED: inte ( 427) 3028 442.7 8.2e-124 XP_016882255 (OMIM: 603734,616532) PREDICTED: inte ( 427) 3028 442.7 8.2e-124 NP_001184052 (OMIM: 603734,616532) interferon regu ( 392) 2634 386.7 5.8e-107 XP_006723261 (OMIM: 603734,616532) PREDICTED: inte ( 452) 2343 345.3 1.9e-94 XP_006723260 (OMIM: 603734,616532) PREDICTED: inte ( 452) 2343 345.3 1.9e-94 NP_001184051 (OMIM: 603734,616532) interferon regu ( 452) 2343 345.3 1.9e-94 NP_001184054 (OMIM: 603734,616532) interferon regu ( 281) 2002 296.6 5.2e-80 NP_001184055 (OMIM: 603734,616532) interferon regu ( 281) 2002 296.6 5.2e-80 XP_006723263 (OMIM: 603734,616532) PREDICTED: inte ( 417) 1949 289.2 1.3e-77 NP_001184053 (OMIM: 603734,616532) interferon regu ( 300) 1422 214.1 3.8e-55 XP_006723264 (OMIM: 603734,616532) PREDICTED: inte ( 306) 1317 199.2 1.2e-50 XP_006723265 (OMIM: 603734,616532) PREDICTED: inte ( 306) 1317 199.2 1.2e-50 NP_001184057 (OMIM: 603734,616532) interferon regu ( 154) 688 109.5 6.2e-24 NP_001184056 (OMIM: 603734,616532) interferon regu ( 154) 688 109.5 6.2e-24 NP_002154 (OMIM: 601565,614893,614894) interferon ( 426) 476 79.6 1.7e-14 XP_011514466 (OMIM: 607218,612245,612251) PREDICTE ( 488) 399 68.7 3.8e-11 XP_011514465 (OMIM: 607218,612245,612251) PREDICTE ( 488) 399 68.7 3.8e-11 XP_011514464 (OMIM: 607218,612245,612251) PREDICTE ( 488) 399 68.7 3.8e-11 NP_001092097 (OMIM: 607218,612245,612251) interfer ( 498) 393 67.8 6.9e-11 NP_001092100 (OMIM: 607218,612245,612251) interfer ( 498) 393 67.8 6.9e-11 NP_116032 (OMIM: 607218,612245,612251) interferon ( 498) 393 67.8 6.9e-11 XP_011514463 (OMIM: 607218,612245,612251) PREDICTE ( 504) 388 67.1 1.1e-10 XP_011514461 (OMIM: 607218,612245,612251) PREDICTE ( 514) 383 66.4 1.9e-10 XP_011514462 (OMIM: 607218,612245,612251) PREDICTE ( 514) 383 66.4 1.9e-10 XP_006716037 (OMIM: 607218,612245,612251) PREDICTE ( 514) 383 66.4 1.9e-10 XP_005250374 (OMIM: 607218,612245,612251) PREDICTE ( 514) 383 66.4 1.9e-10 XP_011514460 (OMIM: 607218,612245,612251) PREDICTE ( 514) 383 66.4 1.9e-10 NP_001092099 (OMIM: 607218,612245,612251) interfer ( 514) 383 66.4 1.9e-10 NP_006138 (OMIM: 119300,119500,607199,608864) inte ( 467) 373 65.0 4.7e-10 XP_006715153 (OMIM: 601900,611724) PREDICTED: inte ( 415) 372 64.8 4.8e-10 NP_001229381 (OMIM: 607218,612245,612251) interfer ( 412) 352 61.9 3.4e-09 NP_001182215 (OMIM: 601900,611724) interferon regu ( 450) 352 62.0 3.6e-09 NP_002451 (OMIM: 601900,611724) interferon regulat ( 451) 347 61.3 6e-09 NP_006075 (OMIM: 147574) interferon regulatory fac ( 393) 339 60.1 1.2e-08 XP_016873163 (OMIM: 605047,616345) PREDICTED: inte ( 210) 306 55.2 1.8e-07 NP_001193625 (OMIM: 119300,119500,607199,608864) i ( 372) 291 53.2 1.3e-06 NP_002190 (OMIM: 147576) interferon regulatory fac ( 349) 277 51.2 4.9e-06 XP_011541680 (OMIM: 147575,211980,613659) PREDICTE ( 284) 263 49.2 1.6e-05 NP_002189 (OMIM: 147575,211980,613659) interferon ( 325) 263 49.2 1.8e-05 XP_016878688 (OMIM: 601565,614893,614894) PREDICTE ( 222) 216 42.4 0.0014 NP_004020 (OMIM: 605047,616345) interferon regulat ( 474) 211 41.9 0.0042 XP_005252966 (OMIM: 605047,616345) PREDICTED: inte ( 487) 211 41.9 0.0043 XP_011518368 (OMIM: 605047,616345) PREDICTED: inte ( 502) 211 41.9 0.0044 NP_001563 (OMIM: 605047,616345) interferon regulat ( 503) 211 41.9 0.0044 XP_005252964 (OMIM: 605047,616345) PREDICTED: inte ( 515) 211 41.9 0.0045 NP_004022 (OMIM: 605047,616345) interferon regulat ( 516) 211 41.9 0.0045 XP_005252963 (OMIM: 605047,616345) PREDICTED: inte ( 516) 211 41.9 0.0045 >>NP_001562 (OMIM: 603734,616532) interferon regulatory (427 aa) initn: 3028 init1: 3028 opt: 3028 Z-score: 2343.8 bits: 442.7 E(85289): 8.2e-124 Smith-Waterman score: 3028; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427) 10 20 30 40 50 60 pF1KB5 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 WPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 PNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 RLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLVEGMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLVEGMD 370 380 390 400 410 420 pF1KB5 FQGPGES ::::::: NP_001 FQGPGES >>XP_016882256 (OMIM: 603734,616532) PREDICTED: interfer (427 aa) initn: 3028 init1: 3028 opt: 3028 Z-score: 2343.8 bits: 442.7 E(85289): 8.2e-124 Smith-Waterman score: 3028; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427) 10 20 30 40 50 60 pF1KB5 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 WPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 PNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 RLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLVEGMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLVEGMD 370 380 390 400 410 420 pF1KB5 FQGPGES ::::::: XP_016 FQGPGES >>XP_016882255 (OMIM: 603734,616532) PREDICTED: interfer (427 aa) initn: 3028 init1: 3028 opt: 3028 Z-score: 2343.8 bits: 442.7 E(85289): 8.2e-124 Smith-Waterman score: 3028; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427) 10 20 30 40 50 60 pF1KB5 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 WPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 PNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 RLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLVEGMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLVEGMD 370 380 390 400 410 420 pF1KB5 FQGPGES ::::::: XP_016 FQGPGES >>NP_001184052 (OMIM: 603734,616532) interferon regulato (392 aa) initn: 2634 init1: 2634 opt: 2634 Z-score: 2041.4 bits: 386.7 E(85289): 5.8e-107 Smith-Waterman score: 2634; 100.0% identity (100.0% similar) in 372 aa overlap (56-427:21-392) 30 40 50 60 70 80 pF1KB5 WVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEATGAYVPGRDKPDLPTWKRNFRSALN :::::::::::::::::::::::::::::: NP_001 MVGRKQGWSCRVTGIKPGKPAWAEATGAYVPGRDKPDLPTWKRNFRSALN 10 20 30 40 50 90 100 110 120 130 140 pF1KB5 RKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQPDTSPDTNGGGSTSDTQEDILDELLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQPDTSPDTNGGGSTSDTQEDILDELLG 60 70 80 90 100 110 150 160 170 180 190 200 pF1KB5 NMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPTPFPNLGPSENPLKRLLVPGEEWEFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPTPFPNLGPSENPLKRLLVPGEEWEFE 120 130 140 150 160 170 210 220 230 240 250 260 pF1KB5 VTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPGWPVTLPDPGMSLTDRGVMSYVRHVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPGWPVTLPDPGMSLTDRGVMSYVRHVL 180 190 200 210 220 230 270 280 290 300 310 320 pF1KB5 SCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPF 240 250 260 270 280 290 330 340 350 360 370 380 pF1KB5 IVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVEMARVGGAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVEMARVGGAS 300 310 320 330 340 350 390 400 410 420 pF1KB5 SLENTVDLHISNSHPLSLTSDQYKAYLQDLVEGMDFQGPGES :::::::::::::::::::::::::::::::::::::::::: NP_001 SLENTVDLHISNSHPLSLTSDQYKAYLQDLVEGMDFQGPGES 360 370 380 390 >>XP_006723261 (OMIM: 603734,616532) PREDICTED: interfer (452 aa) initn: 2343 init1: 2343 opt: 2343 Z-score: 1816.7 bits: 345.3 E(85289): 1.9e-94 Smith-Waterman score: 2343; 100.0% identity (100.0% similar) in 327 aa overlap (1-327:1-327) 10 20 30 40 50 60 pF1KB5 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 WPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 PNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTK ::::::::::::::::::::::::::: XP_006 PNSGHGPDGEVPKDKEGGVFDLGPFIVGSWAPRSDYLHGRKRTLTTLCPLVLCGGVMAPG 310 320 330 340 350 360 >>XP_006723260 (OMIM: 603734,616532) PREDICTED: interfer (452 aa) initn: 2343 init1: 2343 opt: 2343 Z-score: 1816.7 bits: 345.3 E(85289): 1.9e-94 Smith-Waterman score: 2343; 100.0% identity (100.0% similar) in 327 aa overlap (1-327:1-327) 10 20 30 40 50 60 pF1KB5 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 WPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 PNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTK ::::::::::::::::::::::::::: XP_006 PNSGHGPDGEVPKDKEGGVFDLGPFIVGSWAPRSDYLHGRKRTLTTLCPLVLCGGVMAPG 310 320 330 340 350 360 >>NP_001184051 (OMIM: 603734,616532) interferon regulato (452 aa) initn: 2343 init1: 2343 opt: 2343 Z-score: 1816.7 bits: 345.3 E(85289): 1.9e-94 Smith-Waterman score: 2343; 100.0% identity (100.0% similar) in 327 aa overlap (1-327:1-327) 10 20 30 40 50 60 pF1KB5 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 WPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 PNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTK ::::::::::::::::::::::::::: NP_001 PNSGHGPDGEVPKDKEGGVFDLGPFIVGSWAPRSDYLHGRKRTLTTLCPLVLCGGVMAPG 310 320 330 340 350 360 >>NP_001184054 (OMIM: 603734,616532) interferon regulato (281 aa) initn: 2002 init1: 2002 opt: 2002 Z-score: 1557.4 bits: 296.6 E(85289): 5.2e-80 Smith-Waterman score: 2002; 100.0% identity (100.0% similar) in 281 aa overlap (147-427:1-281) 120 130 140 150 160 170 pF1KB5 FSQPDTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSL :::::::::::::::::::::::::::::: NP_001 MVLAPLPDPGPPSLAVAPEPCPQPLRSPSL 10 20 30 180 190 200 210 220 230 pF1KB5 DNPTPFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DNPTPFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDR 40 50 60 70 80 90 240 250 260 270 280 290 pF1KB5 TLPGWPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLPGWPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVS 100 110 120 130 140 150 300 310 320 330 340 350 pF1KB5 EELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQ 160 170 180 190 200 210 360 370 380 390 400 410 pF1KB5 PWTKRLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PWTKRLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLV 220 230 240 250 260 270 420 pF1KB5 EGMDFQGPGES ::::::::::: NP_001 EGMDFQGPGES 280 >>NP_001184055 (OMIM: 603734,616532) interferon regulato (281 aa) initn: 2002 init1: 2002 opt: 2002 Z-score: 1557.4 bits: 296.6 E(85289): 5.2e-80 Smith-Waterman score: 2002; 100.0% identity (100.0% similar) in 281 aa overlap (147-427:1-281) 120 130 140 150 160 170 pF1KB5 FSQPDTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSL :::::::::::::::::::::::::::::: NP_001 MVLAPLPDPGPPSLAVAPEPCPQPLRSPSL 10 20 30 180 190 200 210 220 230 pF1KB5 DNPTPFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DNPTPFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDR 40 50 60 70 80 90 240 250 260 270 280 290 pF1KB5 TLPGWPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLPGWPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVS 100 110 120 130 140 150 300 310 320 330 340 350 pF1KB5 EELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQ 160 170 180 190 200 210 360 370 380 390 400 410 pF1KB5 PWTKRLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PWTKRLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLV 220 230 240 250 260 270 420 pF1KB5 EGMDFQGPGES ::::::::::: NP_001 EGMDFQGPGES 280 >>XP_006723263 (OMIM: 603734,616532) PREDICTED: interfer (417 aa) initn: 1949 init1: 1949 opt: 1949 Z-score: 1514.2 bits: 289.2 E(85289): 1.3e-77 Smith-Waterman score: 1949; 100.0% identity (100.0% similar) in 272 aa overlap (56-327:21-292) 30 40 50 60 70 80 pF1KB5 WVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEATGAYVPGRDKPDLPTWKRNFRSALN :::::::::::::::::::::::::::::: XP_006 MVGRKQGWSCRVTGIKPGKPAWAEATGAYVPGRDKPDLPTWKRNFRSALN 10 20 30 40 50 90 100 110 120 130 140 pF1KB5 RKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQPDTSPDTNGGGSTSDTQEDILDELLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQPDTSPDTNGGGSTSDTQEDILDELLG 60 70 80 90 100 110 150 160 170 180 190 200 pF1KB5 NMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPTPFPNLGPSENPLKRLLVPGEEWEFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPTPFPNLGPSENPLKRLLVPGEEWEFE 120 130 140 150 160 170 210 220 230 240 250 260 pF1KB5 VTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPGWPVTLPDPGMSLTDRGVMSYVRHVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPGWPVTLPDPGMSLTDRGVMSYVRHVL 180 190 200 210 220 230 270 280 290 300 310 320 pF1KB5 SCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPF 240 250 260 270 280 290 330 340 350 360 370 380 pF1KB5 IVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVEMARVGGAS :: XP_006 IVGSWAPRSDYLHGRKRTLTTLCPLVLCGGVMAPGPAVDQEARDGQGCAHVPQGLGRNGP 300 310 320 330 340 350 427 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 16:14:56 2016 done: Thu Nov 3 16:14:57 2016 Total Scan time: 9.110 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]