FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5166, 158 aa 1>>>pF1KB5166 158 - 158 aa - 158 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4547+/-0.000735; mu= 6.6369+/- 0.044 mean_var=105.5651+/-21.460, 0's: 0 Z-trim(111.7): 104 B-trim: 5 in 1/50 Lambda= 0.124829 statistics sampled from 12437 (12555) to 12437 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.386), width: 16 Scan time: 1.720 The best scores are: opt bits E(32554) CCDS44567.1 LMO2 gene_id:4005|Hs108|chr11 ( 158) 1142 215.4 1.2e-56 CCDS7888.2 LMO2 gene_id:4005|Hs108|chr11 ( 227) 1142 215.5 1.6e-56 CCDS58118.1 LMO1 gene_id:4004|Hs108|chr11 ( 155) 578 113.8 4.3e-26 CCDS44534.1 LMO1 gene_id:4004|Hs108|chr11 ( 156) 578 113.8 4.4e-26 CCDS58211.1 LMO3 gene_id:55885|Hs108|chr12 ( 156) 567 111.8 1.7e-25 CCDS58212.1 LMO3 gene_id:55885|Hs108|chr12 ( 163) 567 111.9 1.8e-25 CCDS8678.1 LMO3 gene_id:55885|Hs108|chr12 ( 145) 565 111.5 2.1e-25 CCDS713.1 LMO4 gene_id:8543|Hs108|chr1 ( 165) 451 91.0 3.5e-19 CCDS30962.1 LHX9 gene_id:56956|Hs108|chr1 ( 388) 348 72.7 2.7e-13 CCDS1338.1 LHX4 gene_id:89884|Hs108|chr1 ( 390) 348 72.7 2.7e-13 CCDS1393.1 LHX9 gene_id:56956|Hs108|chr1 ( 397) 348 72.7 2.7e-13 CCDS6853.1 LHX2 gene_id:9355|Hs108|chr9 ( 406) 348 72.7 2.8e-13 CCDS6994.1 LHX3 gene_id:8022|Hs108|chr9 ( 397) 342 71.6 5.8e-13 CCDS6995.1 LHX3 gene_id:8022|Hs108|chr9 ( 402) 341 71.4 6.6e-13 CCDS10290.1 ISL2 gene_id:64843|Hs108|chr15 ( 359) 335 70.3 1.3e-12 CCDS11316.1 LHX1 gene_id:3975|Hs108|chr17 ( 406) 330 69.4 2.6e-12 CCDS43314.1 ISL1 gene_id:3670|Hs108|chr5 ( 349) 324 68.3 4.9e-12 CCDS58008.1 LHX8 gene_id:431707|Hs108|chr1 ( 346) 320 67.6 8.1e-12 CCDS30756.1 LHX8 gene_id:431707|Hs108|chr1 ( 356) 320 67.6 8.2e-12 CCDS6866.2 LMX1B gene_id:4010|Hs108|chr9 ( 395) 319 67.4 1e-11 CCDS55342.1 LMX1B gene_id:4010|Hs108|chr9 ( 402) 319 67.4 1e-11 CCDS55343.1 LMX1B gene_id:4010|Hs108|chr9 ( 406) 319 67.4 1e-11 CCDS9171.1 LHX5 gene_id:64211|Hs108|chr12 ( 402) 313 66.4 2.2e-11 CCDS1247.1 LMX1A gene_id:4009|Hs108|chr1 ( 382) 308 65.4 3.9e-11 >>CCDS44567.1 LMO2 gene_id:4005|Hs108|chr11 (158 aa) initn: 1142 init1: 1142 opt: 1142 Z-score: 1130.7 bits: 215.4 E(32554): 1.2e-56 Smith-Waterman score: 1142; 100.0% identity (100.0% similar) in 158 aa overlap (1-158:1-158) 10 20 30 40 50 60 pF1KB5 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF 70 80 90 100 110 120 130 140 150 pF1KB5 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI :::::::::::::::::::::::::::::::::::::: CCDS44 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI 130 140 150 >>CCDS7888.2 LMO2 gene_id:4005|Hs108|chr11 (227 aa) initn: 1142 init1: 1142 opt: 1142 Z-score: 1128.4 bits: 215.5 E(32554): 1.6e-56 Smith-Waterman score: 1142; 100.0% identity (100.0% similar) in 158 aa overlap (1-158:70-227) 10 20 30 pF1KB5 MSSAIERKSLDPSEEPVDEVLQIPPSLLTC :::::::::::::::::::::::::::::: CCDS78 APEGVRAPAAGQPRATKGAPPPPGTPPPSPMSSAIERKSLDPSEEPVDEVLQIPPSLLTC 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB5 GGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 GGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFGQ 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB5 DGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQDIYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 DGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQDIYE 160 170 180 190 200 210 pF1KB5 WTKINGMI :::::::: CCDS78 WTKINGMI 220 >>CCDS58118.1 LMO1 gene_id:4004|Hs108|chr11 (155 aa) initn: 653 init1: 565 opt: 578 Z-score: 581.8 bits: 113.8 E(32554): 4.3e-26 Smith-Waterman score: 578; 59.1% identity (81.9% similar) in 127 aa overlap (30-156:23-148) 10 20 30 40 50 60 pF1KB5 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC :.::...: :::.:::.:.:::::::.: : CCDS58 MVLDQEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACC 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF ::::::: :: : . ::::::::::: : ::.:.: : :.::.::..:.::::.:: CCDS58 DCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCF 60 70 80 90 100 110 130 140 150 pF1KB5 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI : :...:::::...: :. :.:..: :: ..:: CCDS58 ACQLCNQRFCVGDKFFLKNNMILCQMD-YEEGQLNGTFESQVQ 120 130 140 150 >>CCDS44534.1 LMO1 gene_id:4004|Hs108|chr11 (156 aa) initn: 653 init1: 565 opt: 578 Z-score: 581.8 bits: 113.8 E(32554): 4.4e-26 Smith-Waterman score: 578; 59.1% identity (81.9% similar) in 127 aa overlap (30-156:24-149) 10 20 30 40 50 60 pF1KB5 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC :.::...: :::.:::.:.:::::::.: : CCDS44 MMVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACC 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF ::::::: :: : . ::::::::::: : ::.:.: : :.::.::..:.::::.:: CCDS44 DCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCF 60 70 80 90 100 110 130 140 150 pF1KB5 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI : :...:::::...: :. :.:..: :: ..:: CCDS44 ACQLCNQRFCVGDKFFLKNNMILCQMD-YEEGQLNGTFESQVQ 120 130 140 150 >>CCDS58211.1 LMO3 gene_id:55885|Hs108|chr12 (156 aa) initn: 640 init1: 552 opt: 567 Z-score: 571.1 bits: 111.8 E(32554): 1.7e-25 Smith-Waterman score: 567; 56.0% identity (78.4% similar) in 134 aa overlap (19-150:11-144) 10 20 30 40 50 pF1KB5 MSSAIERKSLDPSEEPVDEVLQIPPSLLT--CGGCQQNIGDRYFLKAIDQYWHEDCLSCD ..:.. :. :.::...: :::.:::.:.:::::::.: CCDS58 MQKKEKSFGIQMLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCA 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 LCGCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLE : ::::::: :: : . ::::::::::: : ::.:.: : :.::.::.::.::::. CCDS58 CCDCRLGEVGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLD 60 70 80 90 100 110 120 130 140 150 pF1KB5 CFKCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI :: : :...:::::...: :. :.:. : : CCDS58 CFACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR 120 130 140 150 >>CCDS58212.1 LMO3 gene_id:55885|Hs108|chr12 (163 aa) initn: 640 init1: 552 opt: 567 Z-score: 570.8 bits: 111.9 E(32554): 1.8e-25 Smith-Waterman score: 567; 56.0% identity (78.4% similar) in 134 aa overlap (19-150:18-151) 10 20 30 40 50 pF1KB5 MSSAIERKSLDPSEEPVDEVLQIPPSLLT--CGGCQQNIGDRYFLKAIDQYWHEDCLSCD ..:.. :. :.::...: :::.:::.:.:::::::.: CCDS58 MLMEGGRAAAARNVSSIQMLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCA 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 LCGCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLE : ::::::: :: : . ::::::::::: : ::.:.: : :.::.::.::.::::. CCDS58 CCDCRLGEVGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLD 60 70 80 90 100 110 120 130 140 150 pF1KB5 CFKCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI :: : :...:::::...: :. :.:. : : CCDS58 CFACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR 120 130 140 150 160 >>CCDS8678.1 LMO3 gene_id:55885|Hs108|chr12 (145 aa) initn: 640 init1: 552 opt: 565 Z-score: 569.6 bits: 111.5 E(32554): 2.1e-25 Smith-Waterman score: 565; 60.3% identity (81.0% similar) in 121 aa overlap (30-150:13-133) 10 20 30 40 50 60 pF1KB5 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC :.::...: :::.:::.:.:::::::.: : CCDS86 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACC 10 20 30 40 70 80 90 100 110 120 pF1KB5 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF ::::::: :: : . ::::::::::: : ::.:.: : :.::.::.::.::::.:: CCDS86 DCRLGEVGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCF 50 60 70 80 90 100 130 140 150 pF1KB5 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI : :...:::::...: :. :.:. : : CCDS86 ACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR 110 120 130 140 >>CCDS713.1 LMO4 gene_id:8543|Hs108|chr1 (165 aa) initn: 492 init1: 436 opt: 451 Z-score: 457.8 bits: 91.0 E(32554): 3.5e-19 Smith-Waterman score: 451; 43.4% identity (69.2% similar) in 143 aa overlap (22-158:9-150) 10 20 30 40 50 pF1KB5 MSSAIERKSLDPSEEPVDEVLQIPP------SLLTCGGCQQNIGDRYFLKAIDQYWHEDC : :: : :.:: .:.::..: :.:.::: : CCDS71 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRC 10 20 30 40 60 70 80 90 100 110 pF1KB5 LSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKV :.:. : .::..: : : : ::: ::.::::..: :..: . : : :..::.. .: CCDS71 LKCSCCQAQLGDIGTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNV 50 60 70 80 90 100 120 130 140 150 pF1KB5 YHLECFKCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI :::.:: :..:.... :::. ::... ::.: . ::: . CCDS71 YHLKCFTCSTCRNRLVPGDRFHYINGSLFCEHD-RPTALINGHLNSLQSNPLLPDQKVC 110 120 130 140 150 160 >>CCDS30962.1 LHX9 gene_id:56956|Hs108|chr1 (388 aa) initn: 347 init1: 181 opt: 348 Z-score: 352.2 bits: 72.7 E(32554): 2.7e-13 Smith-Waterman score: 348; 42.1% identity (66.1% similar) in 121 aa overlap (25-144:59-174) 10 20 30 40 50 pF1KB5 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDC :.: :.:: .:.:::.: :.:. :: : CCDS30 ERRSKTEARLAKGAQLNGRDAGMPPLSPEKPAL--CAGCGGKISDRYYLLAVDKQWHLRC 30 40 50 60 70 80 60 70 80 90 100 110 pF1KB5 LSCDLCGCRLG-EVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDK :.: : :.:. : . : : :..:: : :. . :: : : : ::.::..:. CCDS30 LKC--CECKLALESELTCFAKDGSIYCKEDYYRRFSVQR-CARCHLGISASEMVMRARDS 90 100 110 120 130 140 120 130 140 150 pF1KB5 VYHLECFKCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI :::: :: :..:.: . .::.. . .: . : CCDS30 VYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQLSYTELAAKSGGLA 150 160 170 180 190 200 CCDS30 LPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRT 210 220 230 240 250 260 >>CCDS1338.1 LHX4 gene_id:89884|Hs108|chr1 (390 aa) initn: 286 init1: 124 opt: 348 Z-score: 352.2 bits: 72.7 E(32554): 2.7e-13 Smith-Waterman score: 348; 34.2% identity (68.5% similar) in 149 aa overlap (12-155:8-150) 10 20 30 40 50 pF1KB5 MSSAIERKSLDPSEEPVD---EVLQIPPSLLT-CGGCQQNIGDRYFLKAIDQYWHEDCLS :.: : :.: .: . . :.::.:.: :...::..:..:: .::. CCDS13 MMQSATVPAEGAVKGLPEMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLK 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 CDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYH : : .:.. : . . : :..:... :: :..:.. : ... ...: ::: CCDS13 CADCQMQLAD---RCFSRAGSVYCKEDFFKRFGTK--CTACQQGIPPTQVVRKAQDFVYH 60 70 80 90 100 110 120 130 140 150 pF1KB5 LECFKCAACQKHFCVGDR-YLLINSDIVCEQDIYEWTKINGMI :.:: : :.... .::. ::. .. .::..: :: .: : CCDS13 LHCFACIICNRQLATGDEFYLMEDGRLVCKED-YETAKQNDDSEAGAKRPRTTITAKQLE 120 130 140 150 160 170 CCDS13 TLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKS 180 190 200 210 220 230 158 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:22:22 2016 done: Fri Nov 4 03:22:22 2016 Total Scan time: 1.720 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]