FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5166, 158 aa 1>>>pF1KB5166 158 - 158 aa - 158 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4488+/-0.000321; mu= 12.4272+/- 0.020 mean_var=113.1672+/-23.594, 0's: 0 Z-trim(118.7): 293 B-trim: 1712 in 2/52 Lambda= 0.120563 statistics sampled from 31491 (31850) to 31491 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.748), E-opt: 0.2 (0.373), width: 16 Scan time: 5.280 The best scores are: opt bits E(85289) XP_016873219 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 1142 208.5 3.6e-54 XP_016873222 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 1142 208.5 3.6e-54 NP_001135788 (OMIM: 180385) rhombotin-2 isoform 2 ( 158) 1142 208.5 3.6e-54 XP_016873217 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 1142 208.5 3.6e-54 XP_005252978 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 1142 208.5 3.6e-54 XP_016873221 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 1142 208.5 3.6e-54 XP_016873220 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 1142 208.5 3.6e-54 NP_001135787 (OMIM: 180385) rhombotin-2 isoform 2 ( 158) 1142 208.5 3.6e-54 XP_016873218 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 1142 208.5 3.6e-54 XP_016873216 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 1142 208.5 3.6e-54 NP_005565 (OMIM: 180385) rhombotin-2 isoform 1 [Ho ( 227) 1142 208.7 4.5e-54 XP_011518401 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145) 578 110.4 1.1e-24 XP_011518400 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145) 578 110.4 1.1e-24 NP_001257357 (OMIM: 186921) rhombotin-1 isoform b ( 155) 578 110.4 1.2e-24 NP_002306 (OMIM: 186921) rhombotin-1 isoform a [Ho ( 156) 578 110.4 1.2e-24 XP_006718291 (OMIM: 186921) PREDICTED: rhombotin-1 ( 193) 578 110.5 1.4e-24 NP_001230540 (OMIM: 180386) LIM domain only protei ( 156) 567 108.5 4.5e-24 NP_001230541 (OMIM: 180386) LIM domain only protei ( 163) 567 108.5 4.7e-24 NP_001230538 (OMIM: 180386) LIM domain only protei ( 145) 565 108.1 5.5e-24 NP_001230539 (OMIM: 180386) LIM domain only protei ( 145) 565 108.1 5.5e-24 XP_006719174 (OMIM: 180386) PREDICTED: LIM domain ( 145) 565 108.1 5.5e-24 XP_006719173 (OMIM: 180386) PREDICTED: LIM domain ( 145) 565 108.1 5.5e-24 NP_001001395 (OMIM: 180386) LIM domain only protei ( 145) 565 108.1 5.5e-24 XP_011519065 (OMIM: 180386) PREDICTED: LIM domain ( 145) 565 108.1 5.5e-24 NP_061110 (OMIM: 180386) LIM domain only protein 3 ( 145) 565 108.1 5.5e-24 XP_011519064 (OMIM: 180386) PREDICTED: LIM domain ( 145) 565 108.1 5.5e-24 XP_005271348 (OMIM: 603129) PREDICTED: LIM domain ( 165) 451 88.4 5.6e-18 NP_006760 (OMIM: 603129) LIM domain transcription ( 165) 451 88.4 5.6e-18 XP_006717386 (OMIM: 603759) PREDICTED: LIM/homeobo ( 314) 348 70.8 2.1e-12 XP_005245407 (OMIM: 606066) PREDICTED: LIM/homeobo ( 336) 348 70.8 2.2e-12 XP_016857338 (OMIM: 606066) PREDICTED: LIM/homeobo ( 378) 348 70.9 2.4e-12 NP_001014434 (OMIM: 606066) LIM/homeobox protein L ( 388) 348 70.9 2.4e-12 NP_203129 (OMIM: 262700,602146) LIM/homeobox prote ( 390) 348 70.9 2.4e-12 NP_064589 (OMIM: 606066) LIM/homeobox protein Lhx9 ( 397) 348 70.9 2.4e-12 XP_011508083 (OMIM: 606066) PREDICTED: LIM/homeobo ( 403) 348 70.9 2.5e-12 NP_004780 (OMIM: 603759) LIM/homeobox protein Lhx2 ( 406) 348 70.9 2.5e-12 XP_005263467 (OMIM: 221750,600577) PREDICTED: LIM/ ( 386) 347 70.7 2.7e-12 NP_835258 (OMIM: 221750,600577) LIM/homeobox prote ( 397) 342 69.8 5e-12 XP_016870657 (OMIM: 221750,600577) PREDICTED: LIM/ ( 373) 341 69.6 5.5e-12 NP_055379 (OMIM: 221750,600577) LIM/homeobox prote ( 402) 341 69.7 5.7e-12 NP_665804 (OMIM: 609481) insulin gene enhancer pro ( 359) 335 68.6 1.1e-11 XP_016877994 (OMIM: 609481) PREDICTED: insulin gen ( 534) 335 68.8 1.4e-11 NP_005559 (OMIM: 601999) LIM/homeobox protein Lhx1 ( 406) 330 67.8 2.2e-11 NP_002193 (OMIM: 600366) insulin gene enhancer pro ( 349) 324 66.6 4.1e-11 NP_001243043 (OMIM: 604425) LIM/homeobox protein L ( 346) 320 65.9 6.5e-11 NP_001001933 (OMIM: 604425) LIM/homeobox protein L ( 356) 320 66.0 6.7e-11 XP_016856806 (OMIM: 604425) PREDICTED: LIM/homeobo ( 363) 320 66.0 6.8e-11 XP_016856805 (OMIM: 604425) PREDICTED: LIM/homeobo ( 363) 320 66.0 6.8e-11 NP_002307 (OMIM: 161200,602575) LIM homeobox trans ( 395) 319 65.8 8.1e-11 NP_001167618 (OMIM: 161200,602575) LIM homeobox tr ( 402) 319 65.8 8.1e-11 >>XP_016873219 (OMIM: 180385) PREDICTED: rhombotin-2 iso (158 aa) initn: 1142 init1: 1142 opt: 1142 Z-score: 1093.6 bits: 208.5 E(85289): 3.6e-54 Smith-Waterman score: 1142; 100.0% identity (100.0% similar) in 158 aa overlap (1-158:1-158) 10 20 30 40 50 60 pF1KB5 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF 70 80 90 100 110 120 130 140 150 pF1KB5 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI :::::::::::::::::::::::::::::::::::::: XP_016 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI 130 140 150 >>XP_016873222 (OMIM: 180385) PREDICTED: rhombotin-2 iso (158 aa) initn: 1142 init1: 1142 opt: 1142 Z-score: 1093.6 bits: 208.5 E(85289): 3.6e-54 Smith-Waterman score: 1142; 100.0% identity (100.0% similar) in 158 aa overlap (1-158:1-158) 10 20 30 40 50 60 pF1KB5 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF 70 80 90 100 110 120 130 140 150 pF1KB5 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI :::::::::::::::::::::::::::::::::::::: XP_016 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI 130 140 150 >>NP_001135788 (OMIM: 180385) rhombotin-2 isoform 2 [Hom (158 aa) initn: 1142 init1: 1142 opt: 1142 Z-score: 1093.6 bits: 208.5 E(85289): 3.6e-54 Smith-Waterman score: 1142; 100.0% identity (100.0% similar) in 158 aa overlap (1-158:1-158) 10 20 30 40 50 60 pF1KB5 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF 70 80 90 100 110 120 130 140 150 pF1KB5 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI :::::::::::::::::::::::::::::::::::::: NP_001 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI 130 140 150 >>XP_016873217 (OMIM: 180385) PREDICTED: rhombotin-2 iso (158 aa) initn: 1142 init1: 1142 opt: 1142 Z-score: 1093.6 bits: 208.5 E(85289): 3.6e-54 Smith-Waterman score: 1142; 100.0% identity (100.0% similar) in 158 aa overlap (1-158:1-158) 10 20 30 40 50 60 pF1KB5 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF 70 80 90 100 110 120 130 140 150 pF1KB5 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI :::::::::::::::::::::::::::::::::::::: XP_016 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI 130 140 150 >>XP_005252978 (OMIM: 180385) PREDICTED: rhombotin-2 iso (158 aa) initn: 1142 init1: 1142 opt: 1142 Z-score: 1093.6 bits: 208.5 E(85289): 3.6e-54 Smith-Waterman score: 1142; 100.0% identity (100.0% similar) in 158 aa overlap (1-158:1-158) 10 20 30 40 50 60 pF1KB5 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF 70 80 90 100 110 120 130 140 150 pF1KB5 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI :::::::::::::::::::::::::::::::::::::: XP_005 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI 130 140 150 >>XP_016873221 (OMIM: 180385) PREDICTED: rhombotin-2 iso (158 aa) initn: 1142 init1: 1142 opt: 1142 Z-score: 1093.6 bits: 208.5 E(85289): 3.6e-54 Smith-Waterman score: 1142; 100.0% identity (100.0% similar) in 158 aa overlap (1-158:1-158) 10 20 30 40 50 60 pF1KB5 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF 70 80 90 100 110 120 130 140 150 pF1KB5 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI :::::::::::::::::::::::::::::::::::::: XP_016 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI 130 140 150 >>XP_016873220 (OMIM: 180385) PREDICTED: rhombotin-2 iso (158 aa) initn: 1142 init1: 1142 opt: 1142 Z-score: 1093.6 bits: 208.5 E(85289): 3.6e-54 Smith-Waterman score: 1142; 100.0% identity (100.0% similar) in 158 aa overlap (1-158:1-158) 10 20 30 40 50 60 pF1KB5 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF 70 80 90 100 110 120 130 140 150 pF1KB5 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI :::::::::::::::::::::::::::::::::::::: XP_016 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI 130 140 150 >>NP_001135787 (OMIM: 180385) rhombotin-2 isoform 2 [Hom (158 aa) initn: 1142 init1: 1142 opt: 1142 Z-score: 1093.6 bits: 208.5 E(85289): 3.6e-54 Smith-Waterman score: 1142; 100.0% identity (100.0% similar) in 158 aa overlap (1-158:1-158) 10 20 30 40 50 60 pF1KB5 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF 70 80 90 100 110 120 130 140 150 pF1KB5 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI :::::::::::::::::::::::::::::::::::::: NP_001 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI 130 140 150 >>XP_016873218 (OMIM: 180385) PREDICTED: rhombotin-2 iso (158 aa) initn: 1142 init1: 1142 opt: 1142 Z-score: 1093.6 bits: 208.5 E(85289): 3.6e-54 Smith-Waterman score: 1142; 100.0% identity (100.0% similar) in 158 aa overlap (1-158:1-158) 10 20 30 40 50 60 pF1KB5 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF 70 80 90 100 110 120 130 140 150 pF1KB5 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI :::::::::::::::::::::::::::::::::::::: XP_016 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI 130 140 150 >>XP_016873216 (OMIM: 180385) PREDICTED: rhombotin-2 iso (158 aa) initn: 1142 init1: 1142 opt: 1142 Z-score: 1093.6 bits: 208.5 E(85289): 3.6e-54 Smith-Waterman score: 1142; 100.0% identity (100.0% similar) in 158 aa overlap (1-158:1-158) 10 20 30 40 50 60 pF1KB5 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF 70 80 90 100 110 120 130 140 150 pF1KB5 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI :::::::::::::::::::::::::::::::::::::: XP_016 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI 130 140 150 158 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:22:22 2016 done: Fri Nov 4 03:22:23 2016 Total Scan time: 5.280 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]