FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5177, 217 aa 1>>>pF1KB5177 217 - 217 aa - 217 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5259+/-0.000808; mu= 13.0983+/- 0.049 mean_var=74.0292+/-14.855, 0's: 0 Z-trim(108.7): 46 B-trim: 226 in 1/50 Lambda= 0.149064 statistics sampled from 10323 (10369) to 10323 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.701), E-opt: 0.2 (0.319), width: 16 Scan time: 1.810 The best scores are: opt bits E(32554) CCDS2218.1 GCA gene_id:25801|Hs108|chr2 ( 217) 1477 326.4 8.3e-90 CCDS82527.1 GCA gene_id:25801|Hs108|chr2 ( 198) 1336 296.1 1e-80 CCDS5612.1 SRI gene_id:6717|Hs108|chr7 ( 198) 807 182.3 1.8e-46 CCDS47638.1 SRI gene_id:6717|Hs108|chr7 ( 183) 800 180.8 4.9e-46 CCDS59063.1 SRI gene_id:6717|Hs108|chr7 ( 180) 774 175.2 2.3e-44 CCDS345.1 PEF1 gene_id:553115|Hs108|chr1 ( 284) 397 94.2 8.6e-20 CCDS3854.1 PDCD6 gene_id:10016|Hs108|chr5 ( 191) 364 87.0 8.5e-18 CCDS58940.1 PDCD6 gene_id:10016|Hs108|chr5 ( 189) 355 85.1 3.2e-17 CCDS45246.1 CAPN3 gene_id:825|Hs108|chr15 ( 309) 350 84.2 1e-16 CCDS12489.1 CAPNS1 gene_id:826|Hs108|chr19 ( 268) 348 83.7 1.2e-16 CCDS10085.1 CAPN3 gene_id:825|Hs108|chr15 ( 729) 350 84.4 2.1e-16 CCDS32207.1 CAPN3 gene_id:825|Hs108|chr15 ( 815) 350 84.4 2.3e-16 CCDS45245.1 CAPN3 gene_id:825|Hs108|chr15 ( 821) 350 84.4 2.3e-16 CCDS54010.1 CAPNS2 gene_id:84290|Hs108|chr16 ( 248) 343 82.6 2.4e-16 CCDS47436.1 CAPN11 gene_id:11131|Hs108|chr6 ( 739) 347 83.7 3.3e-16 CCDS73038.1 CAPN8 gene_id:388743|Hs108|chr1 ( 703) 325 79.0 8.3e-15 CCDS53478.1 CAPN2 gene_id:824|Hs108|chr1 ( 622) 324 78.7 8.7e-15 CCDS31035.1 CAPN2 gene_id:824|Hs108|chr1 ( 700) 324 78.8 9.6e-15 CCDS81431.1 CAPN9 gene_id:10753|Hs108|chr1 ( 627) 315 76.8 3.3e-14 CCDS31053.1 CAPN9 gene_id:10753|Hs108|chr1 ( 664) 315 76.8 3.5e-14 CCDS1586.1 CAPN9 gene_id:10753|Hs108|chr1 ( 690) 315 76.8 3.6e-14 CCDS10086.1 CAPN3 gene_id:825|Hs108|chr15 ( 156) 305 74.3 4.7e-14 CCDS44644.1 CAPN1 gene_id:823|Hs108|chr11 ( 714) 310 75.8 7.9e-14 CCDS75223.1 PDCD6 gene_id:10016|Hs108|chr5 ( 121) 298 72.7 1.1e-13 >>CCDS2218.1 GCA gene_id:25801|Hs108|chr2 (217 aa) initn: 1477 init1: 1477 opt: 1477 Z-score: 1725.8 bits: 326.4 E(32554): 8.3e-90 Smith-Waterman score: 1477; 99.5% identity (100.0% similar) in 217 aa overlap (1-217:1-217) 10 20 30 40 50 60 pF1KB5 MAYPGYGGGFGNFSIQVPGMQMGQPVPETGPAILLDGYSGPAYSDTYSSAGDSVYTYFSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS22 MAYPGYGGGFGNFSIQVPGMQMGQPVPETGPAILLDGYSGPAYSDTYSSAGDSVYTYFSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VAGQDGEVDAEELQRCLTQAGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAA :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: CCDS22 VAGQDGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIFFDDYVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS22 LNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIFFDDYVA 130 140 150 160 170 180 190 200 210 pF1KB5 CCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTMAI ::::::::::::::::::::::::::::::::::::: CCDS22 CCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTMAI 190 200 210 >>CCDS82527.1 GCA gene_id:25801|Hs108|chr2 (198 aa) initn: 1336 init1: 1336 opt: 1336 Z-score: 1562.5 bits: 296.1 E(32554): 1e-80 Smith-Waterman score: 1336; 99.5% identity (100.0% similar) in 198 aa overlap (20-217:1-198) 10 20 30 40 50 60 pF1KB5 MAYPGYGGGFGNFSIQVPGMQMGQPVPETGPAILLDGYSGPAYSDTYSSAGDSVYTYFSA ::::::::::::::::::::::::::::::::::::::::: CCDS82 MQMGQPVPETGPAILLDGYSGPAYSDTYSSAGDSVYTYFSA 10 20 30 40 70 80 90 100 110 120 pF1KB5 VAGQDGEVDAEELQRCLTQAGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAA :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: CCDS82 VAGQDGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAA 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 LNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIFFDDYVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 LNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIFFDDYVA 110 120 130 140 150 160 190 200 210 pF1KB5 CCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTMAI ::::::::::::::::::::::::::::::::::::: CCDS82 CCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTMAI 170 180 190 >>CCDS5612.1 SRI gene_id:6717|Hs108|chr7 (198 aa) initn: 857 init1: 778 opt: 807 Z-score: 947.7 bits: 182.3 E(32554): 1.8e-46 Smith-Waterman score: 829; 55.8% identity (77.4% similar) in 217 aa overlap (1-217:1-198) 10 20 30 40 50 60 pF1KB5 MAYPGYGGGFGNFSIQVPGMQMGQPVPETGPAILLDGYSGPAYSDTYSSAGDSVYTYFSA :::::. :. :.. :: : : .:::. ... : .: ::.: CCDS56 MAYPGHPGAGGGY---YPGGYGGAP-------------GGPAFP---GQTQDPLYGYFAA 10 20 30 40 70 80 90 100 110 120 pF1KB5 VAGQDGEVDAEELQRCLTQAGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAA ::::::..::.::::::::.:: : :.::.:::::.:..::::: .: :::: ::::::. CCDS56 VAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAV 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 LNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIFFDDYVA ::.:...:.. : : ::::. .::..:. ::.:::::....:.:::: ::.: ::::.: CCDS56 LNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIA 110 120 130 140 150 160 190 200 210 pF1KB5 CCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTMAI :::::::::: ::.:: ::: .:: ::::.: .:.. CCDS56 CCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMSV 170 180 190 >>CCDS47638.1 SRI gene_id:6717|Hs108|chr7 (183 aa) initn: 814 init1: 778 opt: 800 Z-score: 940.0 bits: 180.8 E(32554): 4.9e-46 Smith-Waterman score: 800; 61.8% identity (85.4% similar) in 178 aa overlap (40-217:9-183) 10 20 30 40 50 60 pF1KB5 FGNFSIQVPGMQMGQPVPETGPAILLDGYSGPAYSDTYSSAGDSVYTYFSAVAGQDGEVD :::. ... : .: ::.:::::::..: CCDS47 MQYGGAPGGPAFP---GQTQDPLYGYFAAVAGQDGQID 10 20 30 70 80 90 100 110 120 pF1KB5 AEELQRCLTQAGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNAWKENFM :.::::::::.:: : :.::.:::::.:..::::: .: :::: ::::::.::.:...:. CCDS47 ADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFI 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 TVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIFFDDYVACCVKLRALT . : : ::::. .::..:. ::.:::::....:.:::: ::.: ::::.:::::::::: CCDS47 SFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALT 100 110 120 130 140 150 190 200 210 pF1KB5 DFFRKRDHLQQGSANFIYDDFLQGTMAI : ::.:: ::: .:: ::::.: .:.. CCDS47 DSFRRRDTAQQGVVNFPYDDFIQCVMSV 160 170 180 >>CCDS59063.1 SRI gene_id:6717|Hs108|chr7 (180 aa) initn: 766 init1: 766 opt: 774 Z-score: 909.9 bits: 175.2 E(32554): 2.3e-44 Smith-Waterman score: 774; 62.9% identity (85.3% similar) in 170 aa overlap (40-209:9-175) 10 20 30 40 50 60 pF1KB5 FGNFSIQVPGMQMGQPVPETGPAILLDGYSGPAYSDTYSSAGDSVYTYFSAVAGQDGEVD :::. ... : .: ::.:::::::..: CCDS59 MQYGGAPGGPAFP---GQTQDPLYGYFAAVAGQDGQID 10 20 30 70 80 90 100 110 120 pF1KB5 AEELQRCLTQAGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNAWKENFM :.::::::::.:: : :.::.:::::.:..::::: .: :::: ::::::.::.:...:. CCDS59 ADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFI 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 TVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIFFDDYVACCVKLRALT . : : ::::. .::..:. ::.:::::....:.:::: ::.: ::::.:::::::::: CCDS59 SFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALT 100 110 120 130 140 150 190 200 210 pF1KB5 DFFRKRDHLQQGSANFIYDDFLQGTMAI : ::.:: ::: .:: ::: CCDS59 DSFRRRDTAQQGVVNFPYDDVSLRN 160 170 180 >>CCDS345.1 PEF1 gene_id:553115|Hs108|chr1 (284 aa) initn: 368 init1: 263 opt: 397 Z-score: 468.8 bits: 94.2 E(32554): 8.6e-20 Smith-Waterman score: 398; 34.0% identity (61.9% similar) in 215 aa overlap (7-214:78-279) 10 20 30 pF1KB5 MAYPGYGGGFGNFSIQVPGMQMGQPVPETGPAIL-- :: .:. .:: .::: : . : CCDS34 GPAPGGPYGPPAGGGPYGHPNPGMFPSGTPGGPYGG---AAPGGPYGQPPPSSYGAQQPG 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB5 LDGYSG-PAYSDTYSSAGDSVYTYFSAV-AGQDGEVDAEELQRCLTQAGINGTYSPFSLE : : .: : : .:..:..: . ..: .. .::. :: .: ..: :. : CCDS34 LYGQGGAPPNVD------PEAYSWFQSVDSDHSGYISMKELK----QALVNCNWSSFNDE 110 120 130 140 150 100 110 120 130 140 150 pF1KB5 TCRIMIAMLDRDHTGKMGFNAFKELWAALNAWKENFMTVDQDGSGTVEHHELRQAIGLMG :: .:: :.:. ..:.. .:. :: .. ::. :. :.: ::.. . ::.::.. :: CCDS34 TCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQALSQMG 160 170 180 190 200 210 160 170 180 190 200 pF1KB5 YRLSPQTLTTIVKRY---SKNGRIFFDDYVACCVKLRALTDFFRKRDHLQQGSANFIYDD : :::: .:.:: : : . .: .. :..:..::. ::..: ::. . ..: CCDS34 YNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRLSFED 220 230 240 250 260 270 210 pF1KB5 FLQGTMAI :. : CCDS34 FVTMTASRML 280 >>CCDS3854.1 PDCD6 gene_id:10016|Hs108|chr5 (191 aa) initn: 335 init1: 260 opt: 364 Z-score: 433.0 bits: 87.0 E(32554): 8.5e-18 Smith-Waterman score: 370; 32.5% identity (66.0% similar) in 197 aa overlap (24-217:7-190) 10 20 30 40 50 60 pF1KB5 MAYPGYGGGFGNFSIQVPGMQMGQPVPETGPAILLDGYSGPAYSDTYSSAGDSVYTYFSA .: : .:: ::: . . . . ... :. CCDS38 MAAYSYRPGPGAGP--------GPAAGAALPDQS-FLWNVFQR 10 20 30 70 80 90 100 110 pF1KB5 V-AGQDGEVDAEELQRCLTQAGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWA : ..: .. :::. :. :::..::. : : .:.:.::.. . ..:. : .: CCDS38 VDKDRSGVISDTELQQALS----NGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWK 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB5 ALNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGR--IFFDD .. :.. : : :.:.:: ....::.::.. .::::: : ........:: : ::: CCDS38 YITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDD 100 110 120 130 140 150 180 190 200 210 pF1KB5 YVACCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTMAI .. :. :. :::.::. : :.: . :...:. ...: CCDS38 FIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV 160 170 180 190 >>CCDS58940.1 PDCD6 gene_id:10016|Hs108|chr5 (189 aa) initn: 367 init1: 260 opt: 355 Z-score: 422.6 bits: 85.1 E(32554): 3.2e-17 Smith-Waterman score: 361; 33.0% identity (65.0% similar) in 197 aa overlap (24-217:7-188) 10 20 30 40 50 60 pF1KB5 MAYPGYGGGFGNFSIQVPGMQMGQPVPETGPAILLDGYSGPAYSDTYSSAGDSVYTYFSA .: : .:: ::: . . . . ... :. CCDS58 MAAYSYRPGPGAGP--------GPAAGAALPDQS-FLWNVFQR 10 20 30 70 80 90 100 110 pF1KB5 V-AGQDGEVDAEELQRCLTQAGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWA : ..: .. :::. :. :::..::. : : .:.:.::.. . ..:. : .: CCDS58 VDKDRSGVISDTELQQALS----NGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWK 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB5 ALNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGR--IFFDD .. :.. : : :.:.:: ....::.:: : ::::: : ........:: : ::: CCDS58 YITDWQNVFRTYDRDNSGMIDKNELKQA--LSGYRLSDQFHDILIRKFDRQGRGQIAFDD 100 110 120 130 140 180 190 200 210 pF1KB5 YVACCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTMAI .. :. :. :::.::. : :.: . :...:. ...: CCDS58 FIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV 150 160 170 180 >>CCDS45246.1 CAPN3 gene_id:825|Hs108|chr15 (309 aa) initn: 308 init1: 252 opt: 350 Z-score: 413.7 bits: 84.2 E(32554): 1e-16 Smith-Waterman score: 350; 33.3% identity (65.0% similar) in 180 aa overlap (41-215:129-307) 20 30 40 50 60 70 pF1KB5 GNFSIQVPGMQMGQPVPETGPAILLDGYSGPAYSDTYSSAGDSVYTYFSAVAGQDGEVDA :. :: : .. . :. .::.: :. : CCDS45 SNKELGVDQESEEGKGKTSPDKQKQSPQPQPGSSDQESEEQQQFRNIFKQIAGDDMEICA 100 110 120 130 140 150 80 90 100 110 120 pF1KB5 EELQRCLTQAGINGTYS----PFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNAWKE .::.. :. . .: . :.::.:: :::..: : .::.... :..:: ..::.. CCDS45 DELKKVLNTV-VNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQK 160 170 180 190 200 210 130 140 150 160 170 180 pF1KB5 NFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYS-KNGRIFFDDYVACCVKL : : : :::.. .:.:.:.. :..:. : :. ::. :. : ::... : :.: CCDS45 IFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCFVRL 220 230 240 250 260 270 190 200 210 pF1KB5 RALTDFFRKRDHLQQGSANFIYDDFLQGTMAI ... :. :. .: .. ..:: :: CCDS45 EGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 280 290 300 >>CCDS12489.1 CAPNS1 gene_id:826|Hs108|chr19 (268 aa) initn: 295 init1: 228 opt: 348 Z-score: 412.3 bits: 83.7 E(32554): 1.2e-16 Smith-Waterman score: 350; 30.8% identity (59.7% similar) in 221 aa overlap (5-215:49-266) 10 20 30 pF1KB5 MAYPGYGGGFGNFSIQVPGMQMGQPVPETGPAIL : ::: :. .... : .. . :. : CCDS12 GGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVISA-ISEA--AAQ 20 30 40 50 60 70 40 50 60 70 80 pF1KB5 LDGYSGPA---YSDTYSSAGDSVYTY---FSAVAGQDGEVDAEELQRCLTQAGI---NGT . : ::. .. .. : . :. .::.: ::.: ::. :... . CCDS12 YNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLK 80 90 100 110 120 130 90 100 110 120 130 140 pF1KB5 YSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNAWKENFMTVDQDGSGTVEHHELR . :...::: :.:..: : :::.::. :: :: .. :. . : : :::. :: CCDS12 TDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELP 140 150 160 170 180 190 150 160 170 180 190 200 pF1KB5 QAIGLMGYRLSPQTLTTIVKRYS-KNGRIFFDDYVACCVKLRALTDFFRKRDHLQQGSAN :. :..:. . . :..::: ..: . ::....: :.: :. :.. :. :. . CCDS12 GAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQ 200 210 220 230 240 250 210 pF1KB5 FIYDDFLQGTMAI ...:: :: CCDS12 VNIQEWLQLTMYS 260 217 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:23:14 2016 done: Sat Nov 5 06:23:15 2016 Total Scan time: 1.810 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]