Result of FASTA (omim) for
pF1KB5179
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5179, 395 aa
1>>>pF1KB5179 395 - 395 aa - 395 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7213+/-0.000421; mu= 14.4636+/- 0.026
mean_var=66.4323+/-13.119, 0's: 0 Z-trim(111.4): 25 B-trim: 0 in 0/55
Lambda= 0.157356
statistics sampled from 20005 (20011) to 20005 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.598), E-opt: 0.2 (0.235), width: 16
Scan time: 8.260
The best scores are: opt bits E(85289)
NP_005902 (OMIM: 601468) S-adenosylmethionine synt ( 395) 2635 607.3 2e-173
XP_005269899 (OMIM: 250850,610550) PREDICTED: S-ad ( 395) 2311 533.8 2.8e-151
NP_000420 (OMIM: 250850,610550) S-adenosylmethioni ( 395) 2311 533.8 2.8e-151
XP_005269900 (OMIM: 250850,610550) PREDICTED: S-ad ( 354) 1822 422.7 6.6e-118
>>NP_005902 (OMIM: 601468) S-adenosylmethionine synthase (395 aa)
initn: 2635 init1: 2635 opt: 2635 Z-score: 3234.5 bits: 607.3 E(85289): 2e-173
Smith-Waterman score: 2635; 100.0% identity (100.0% similar) in 395 aa overlap (1-395:1-395)
10 20 30 40 50 60
pF1KB5 MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 VAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVI
310 320 330 340 350 360
370 380 390
pF1KB5 VRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
:::::::::::::::::::::::::::::::::::
NP_005 VRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
370 380 390
>>XP_005269899 (OMIM: 250850,610550) PREDICTED: S-adenos (395 aa)
initn: 2339 init1: 2311 opt: 2311 Z-score: 2837.0 bits: 533.8 E(85289): 2.8e-151
Smith-Waterman score: 2311; 84.3% identity (95.4% similar) in 395 aa overlap (1-395:1-395)
10 20 30 40 50 60
pF1KB5 MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVA
::: ..:. . . ::.:.:::::::::::::::::::::::::::.:::.::::::::
XP_005 MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG
::::.:: ::::: : ::::.:::...::::::::.::::.::::::::::::::::::
XP_005 KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDS
:::::::::.::::::::::::::::::::::::.:::::::..:.:::.: ::::::::
XP_005 VHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDT
::::::::::: :::.:.:.:::::::::.:.. :.::: ::::.::.::::::::::::
XP_005 KTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
.:::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_005 VYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 VAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVI
:::::::.::::::::::::::::..::::::: ::::::.:::::..:.::::::::::
XP_005 VAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVI
310 320 330 340 350 360
370 380 390
pF1KB5 VRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
::::::::::::.:: ::::::. ::::::.:: .
XP_005 VRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF
370 380 390
>>NP_000420 (OMIM: 250850,610550) S-adenosylmethionine s (395 aa)
initn: 2339 init1: 2311 opt: 2311 Z-score: 2837.0 bits: 533.8 E(85289): 2.8e-151
Smith-Waterman score: 2311; 84.3% identity (95.4% similar) in 395 aa overlap (1-395:1-395)
10 20 30 40 50 60
pF1KB5 MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVA
::: ..:. . . ::.:.:::::::::::::::::::::::::::.:::.::::::::
NP_000 MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG
::::.:: ::::: : ::::.:::...::::::::.::::.::::::::::::::::::
NP_000 KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDS
:::::::::.::::::::::::::::::::::::.:::::::..:.:::.: ::::::::
NP_000 VHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDT
::::::::::: :::.:.:.:::::::::.:.. :.::: ::::.::.::::::::::::
NP_000 KTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
.:::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
NP_000 VYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 VAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVI
:::::::.::::::::::::::::..::::::: ::::::.:::::..:.::::::::::
NP_000 VAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVI
310 320 330 340 350 360
370 380 390
pF1KB5 VRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
::::::::::::.:: ::::::. ::::::.:: .
NP_000 VRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF
370 380 390
>>XP_005269900 (OMIM: 250850,610550) PREDICTED: S-adenos (354 aa)
initn: 2093 init1: 1807 opt: 1822 Z-score: 2237.8 bits: 422.7 E(85289): 6.6e-118
Smith-Waterman score: 2015; 76.5% identity (86.1% similar) in 395 aa overlap (1-395:1-354)
10 20 30 40 50 60
pF1KB5 MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVA
::: ..:. . . ::.:.:::::::::::::::::::::::::::.:::.:::::
XP_005 MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVAC----
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG
:::.::::::::::::::::::
XP_005 -------------------------------------GFDFKTCNVLVALEQQSPDIAQC
60 70
130 140 150 160 170 180
pF1KB5 VHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDS
:::::::::.::::::::::::::::::::::::.:::::::..:.:::.: ::::::::
XP_005 VHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDS
80 90 100 110 120 130
190 200 210 220 230 240
pF1KB5 KTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDT
::::::::::: :::.:.:.:::::::::.:.. :.::: ::::.::.::::::::::::
XP_005 KTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDT
140 150 160 170 180 190
250 260 270 280 290 300
pF1KB5 IYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
.:::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_005 VYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
200 210 220 230 240 250
310 320 330 340 350 360
pF1KB5 VAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVI
:::::::.::::::::::::::::..::::::: ::::::.:::::..:.::::::::::
XP_005 VAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVI
260 270 280 290 300 310
370 380 390
pF1KB5 VRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
::::::::::::.:: ::::::. ::::::.:: .
XP_005 VRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF
320 330 340 350
395 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 06:24:34 2016 done: Sat Nov 5 06:24:35 2016
Total Scan time: 8.260 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]