FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5183, 434 aa 1>>>pF1KB5183 434 - 434 aa - 434 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3008+/-0.000447; mu= 16.7960+/- 0.028 mean_var=60.2066+/-12.360, 0's: 0 Z-trim(108.4): 37 B-trim: 640 in 1/48 Lambda= 0.165292 statistics sampled from 16424 (16459) to 16424 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.55), E-opt: 0.2 (0.193), width: 16 Scan time: 7.340 The best scores are: opt bits E(85289) NP_001966 (OMIM: 131360) gamma-enolase [Homo sapie ( 434) 2833 684.6 1.3e-196 NP_001419 (OMIM: 172430) alpha-enolase isoform 1 [ ( 434) 2437 590.2 3.5e-168 NP_001967 (OMIM: 131370,612932) beta-enolase isofo ( 434) 2419 585.9 6.8e-167 XP_011522031 (OMIM: 131370,612932) PREDICTED: beta ( 434) 2419 585.9 6.8e-167 XP_016879835 (OMIM: 131370,612932) PREDICTED: beta ( 434) 2419 585.9 6.8e-167 NP_443739 (OMIM: 131370,612932) beta-enolase isofo ( 434) 2419 585.9 6.8e-167 XP_005256578 (OMIM: 131370,612932) PREDICTED: beta ( 443) 2419 585.9 6.9e-167 XP_006710496 (OMIM: 172430) PREDICTED: alpha-enola ( 434) 2396 580.4 3.1e-165 NP_001188412 (OMIM: 172430) c-myc promoter-binding ( 341) 1964 477.4 2.5e-134 NP_001180432 (OMIM: 131370,612932) beta-enolase is ( 391) 1896 461.2 2.2e-129 XP_006717898 (OMIM: 131375) PREDICTED: enolase 4 i ( 598) 221 61.8 5.5e-09 XP_006717899 (OMIM: 131375) PREDICTED: enolase 4 i ( 582) 220 61.6 6.3e-09 NP_001229628 (OMIM: 131375) enolase 4 [Homo sapien ( 625) 220 61.6 6.7e-09 XP_011538099 (OMIM: 131375) PREDICTED: enolase 4 i ( 583) 146 43.9 0.0013 >>NP_001966 (OMIM: 131360) gamma-enolase [Homo sapiens] (434 aa) initn: 2833 init1: 2833 opt: 2833 Z-score: 3650.8 bits: 684.6 E(85289): 1.3e-196 Smith-Waterman score: 2833; 100.0% identity (100.0% similar) in 434 aa overlap (1-434:1-434) 10 20 30 40 50 60 pF1KB5 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 WAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDE 370 380 390 400 410 420 430 pF1KB5 ARFAGHNFRNPSVL :::::::::::::: NP_001 ARFAGHNFRNPSVL 430 >>NP_001419 (OMIM: 172430) alpha-enolase isoform 1 [Homo (434 aa) initn: 2437 init1: 2437 opt: 2437 Z-score: 3140.4 bits: 590.2 E(85289): 3.5e-168 Smith-Waterman score: 2437; 84.0% identity (96.8% similar) in 431 aa overlap (1-431:1-431) 10 20 30 40 50 60 pF1KB5 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK ::: :: ::::.::::::::::::.:.::::::::::::::::::::::::.:: ::.:: NP_001 MSILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK :: :::.:::.::::::.:. :.:.::::.:.::.:.::::::::::::::::::::::: NP_001 GVSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD :::.:. .:::::::.:::::..:::::::::::::::::::::::::::::::: .::. NP_001 AGAVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFRE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI :::.::::::.::.:::.::::::::::::::::::::::.:.:::.: :: :::::.:. NP_001 AMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDD :::::::::::.:.:::::::::: ::::::. :::. ::..:..::::::::::::::: NP_001 VIGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 WAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLA :.::.::::..:::.::::::::::::: .::.::.::::::::::::::::..:::::: NP_001 WGAWQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDE : ::::::::::::::::::::::::::::::::::::::::::::::::.:::::::.. NP_001 QANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSK 370 380 390 400 410 420 430 pF1KB5 ARFAGHNFRNPSVL :.:::.::::: NP_001 AKFAGRNFRNPLAK 430 >>NP_001967 (OMIM: 131370,612932) beta-enolase isoform 1 (434 aa) initn: 2419 init1: 2419 opt: 2419 Z-score: 3117.2 bits: 585.9 E(85289): 6.8e-167 Smith-Waterman score: 2419; 84.0% identity (95.8% similar) in 431 aa overlap (1-431:1-431) 10 20 30 40 50 60 pF1KB5 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK :...::.:::::::::::::::::.:::: :::::::::::::::::::::::: ::::: NP_001 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK ::::::..::.:..:::... ::::.:::.:..:.::::::::::::::::::::::::: NP_001 GVLKAVENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD :::::. .:::::::.:::: :::::::::::::::::::::::::::::::::: ::.. NP_001 AGAAEKGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI :::.:::::: :::::: ::::::::::::::::::::::.:::::.: ::. ::: .:. NP_001 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDD :::::::::::::.:::::::::: ::.:.:::..:: ::..:...:::::::::::::: NP_001 VIGMDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 WAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLA ::.:..: ..:.:::::::::::::::: .:::.::::::::::::::::::.::::::: NP_001 WATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDE : ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::. NP_001 QSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDK 370 380 390 400 410 420 430 pF1KB5 ARFAGHNFRNPSVL : :::..:::: NP_001 AIFAGRKFRNPKAK 430 >>XP_011522031 (OMIM: 131370,612932) PREDICTED: beta-eno (434 aa) initn: 2419 init1: 2419 opt: 2419 Z-score: 3117.2 bits: 585.9 E(85289): 6.8e-167 Smith-Waterman score: 2419; 84.0% identity (95.8% similar) in 431 aa overlap (1-431:1-431) 10 20 30 40 50 60 pF1KB5 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK :...::.:::::::::::::::::.:::: :::::::::::::::::::::::: ::::: XP_011 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK ::::::..::.:..:::... ::::.:::.:..:.::::::::::::::::::::::::: XP_011 GVLKAVENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD :::::. .:::::::.:::: :::::::::::::::::::::::::::::::::: ::.. XP_011 AGAAEKGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI :::.:::::: :::::: ::::::::::::::::::::::.:::::.: ::. ::: .:. XP_011 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDD :::::::::::::.:::::::::: ::.:.:::..:: ::..:...:::::::::::::: XP_011 VIGMDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 WAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLA ::.:..: ..:.:::::::::::::::: .:::.::::::::::::::::::.::::::: XP_011 WATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDE : ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::. XP_011 QSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDK 370 380 390 400 410 420 430 pF1KB5 ARFAGHNFRNPSVL : :::..:::: XP_011 AIFAGRKFRNPKAK 430 >>XP_016879835 (OMIM: 131370,612932) PREDICTED: beta-eno (434 aa) initn: 2419 init1: 2419 opt: 2419 Z-score: 3117.2 bits: 585.9 E(85289): 6.8e-167 Smith-Waterman score: 2419; 84.0% identity (95.8% similar) in 431 aa overlap (1-431:1-431) 10 20 30 40 50 60 pF1KB5 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK :...::.:::::::::::::::::.:::: :::::::::::::::::::::::: ::::: XP_016 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK ::::::..::.:..:::... ::::.:::.:..:.::::::::::::::::::::::::: XP_016 GVLKAVENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD :::::. .:::::::.:::: :::::::::::::::::::::::::::::::::: ::.. XP_016 AGAAEKGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI :::.:::::: :::::: ::::::::::::::::::::::.:::::.: ::. ::: .:. XP_016 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDD :::::::::::::.:::::::::: ::.:.:::..:: ::..:...:::::::::::::: XP_016 VIGMDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 WAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLA ::.:..: ..:.:::::::::::::::: .:::.::::::::::::::::::.::::::: XP_016 WATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDE : ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::. XP_016 QSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDK 370 380 390 400 410 420 430 pF1KB5 ARFAGHNFRNPSVL : :::..:::: XP_016 AIFAGRKFRNPKAK 430 >>NP_443739 (OMIM: 131370,612932) beta-enolase isoform 1 (434 aa) initn: 2419 init1: 2419 opt: 2419 Z-score: 3117.2 bits: 585.9 E(85289): 6.8e-167 Smith-Waterman score: 2419; 84.0% identity (95.8% similar) in 431 aa overlap (1-431:1-431) 10 20 30 40 50 60 pF1KB5 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK :...::.:::::::::::::::::.:::: :::::::::::::::::::::::: ::::: NP_443 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK ::::::..::.:..:::... ::::.:::.:..:.::::::::::::::::::::::::: NP_443 GVLKAVENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD :::::. .:::::::.:::: :::::::::::::::::::::::::::::::::: ::.. NP_443 AGAAEKGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI :::.:::::: :::::: ::::::::::::::::::::::.:::::.: ::. ::: .:. NP_443 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDD :::::::::::::.:::::::::: ::.:.:::..:: ::..:...:::::::::::::: NP_443 VIGMDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 WAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLA ::.:..: ..:.:::::::::::::::: .:::.::::::::::::::::::.::::::: NP_443 WATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDE : ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::. NP_443 QSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDK 370 380 390 400 410 420 430 pF1KB5 ARFAGHNFRNPSVL : :::..:::: NP_443 AIFAGRKFRNPKAK 430 >>XP_005256578 (OMIM: 131370,612932) PREDICTED: beta-eno (443 aa) initn: 2419 init1: 2419 opt: 2419 Z-score: 3117.1 bits: 585.9 E(85289): 6.9e-167 Smith-Waterman score: 2419; 84.0% identity (95.8% similar) in 431 aa overlap (1-431:10-440) 10 20 30 40 50 pF1KB5 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRD :...::.:::::::::::::::::.:::: ::::::::::::::::::::: XP_005 MAVMRTLRAMAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRD 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 GDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAI ::: :::::::::::..::.:..:::... ::::.:::.:..:.:::::::::::::::: XP_005 GDKGRYLGKGVLKAVENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 LGVSLAVCKAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMIL ::::::::::::::. .:::::::.:::: :::::::::::::::::::::::::::::: XP_005 LGVSLAVCKAGAAEKGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMIL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 PVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAI :::: ::..:::.:::::: :::::: ::::::::::::::::::::::.:::::.: :: XP_005 PVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAI 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB5 DKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVS . ::: .:.:::::::::::::.:::::::::: ::.:.:::..:: ::..:...::::: XP_005 QAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB5 IEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVT :::::::::::.:..: ..:.:::::::::::::::: .:::.::::::::::::::::: XP_005 IEDPFDQDDWATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVT 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB5 EAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLM :.:::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLM 370 380 390 400 410 420 420 430 pF1KB5 RIEEELGDEARFAGHNFRNPSVL :::: :::.: :::..:::: XP_005 RIEEALGDKAIFAGRKFRNPKAK 430 440 >>XP_006710496 (OMIM: 172430) PREDICTED: alpha-enolase i (434 aa) initn: 2396 init1: 2396 opt: 2396 Z-score: 3087.6 bits: 580.4 E(85289): 3.1e-165 Smith-Waterman score: 2396; 82.4% identity (95.6% similar) in 431 aa overlap (1-431:1-431) 10 20 30 40 50 60 pF1KB5 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK ::: :: ::::.::::::::::::.:.::::::::::::::::::::::::.:: ::.:: XP_006 MSILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK :: . . .:: .:::: .. :.:.::::.:.::.:.::::::::::::::::::::::: XP_006 GVSRPIKYINEFLAPALCTQKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD :::.:. .:::::::.:::::..:::::::::::::::::::::::::::::::: .::. XP_006 AGAVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFRE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI :::.::::::.::.:::.::::::::::::::::::::::.:.:::.: :: :::::.:. XP_006 AMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDD :::::::::::.:.:::::::::: ::::::. :::. ::..:..::::::::::::::: XP_006 VIGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 WAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLA :.::.::::..:::.::::::::::::: .::.::.::::::::::::::::..:::::: XP_006 WGAWQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDE : ::::::::::::::::::::::::::::::::::::::::::::::::.:::::::.. XP_006 QANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSK 370 380 390 400 410 420 430 pF1KB5 ARFAGHNFRNPSVL :.:::.::::: XP_006 AKFAGRNFRNPLAK 430 >>NP_001188412 (OMIM: 172430) c-myc promoter-binding pro (341 aa) initn: 1964 init1: 1964 opt: 1964 Z-score: 2532.5 bits: 477.4 E(85289): 2.5e-134 Smith-Waterman score: 1964; 84.9% identity (97.3% similar) in 338 aa overlap (94-431:1-338) 70 80 90 100 110 120 pF1KB5 KAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGA :.:.:::::::::::::::::::::::::: NP_001 MIEMDGTENKSKFGANAILGVSLAVCKAGA 10 20 30 130 140 150 160 170 180 pF1KB5 AERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMR .:. .:::::::.:::::..:::::::::::::::::::::::::::::::: .::.::: NP_001 VEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREAMR 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB5 LGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIG .::::::.::.:::.::::::::::::::::::::::.:.:::.: :: :::::.:.::: NP_001 IGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKVVIG 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB5 MDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAA ::::::::.:.:::::::::: ::::::. :::. ::..:..::::::::::::::::.: NP_001 MDVAASEFFRSGKYDLDFKSPDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDDWGA 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB5 WSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQEN :.::::..:::.::::::::::::: .::.::.::::::::::::::::..::::::: : NP_001 WQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLAQAN 220 230 240 250 260 270 370 380 390 400 410 420 pF1KB5 GWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARF :::::::::::::::::::::::::::::::::::::::::::::::.:::::::..:.: NP_001 GWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKAKF 280 290 300 310 320 330 430 pF1KB5 AGHNFRNPSVL ::.::::: NP_001 AGRNFRNPLAK 340 >>NP_001180432 (OMIM: 131370,612932) beta-enolase isofor (391 aa) initn: 1894 init1: 1894 opt: 1896 Z-score: 2443.9 bits: 461.2 E(85289): 2.2e-129 Smith-Waterman score: 2131; 77.0% identity (86.1% similar) in 431 aa overlap (1-431:1-388) 10 20 30 40 50 60 pF1KB5 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK :...::.:::::::::::::::::.:::: :::::::::::::::::::::::: ::::: NP_001 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK .:::::::::::::::: NP_001 -------------------------------------------AKFGANAILGVSLAVCK 70 130 140 150 160 170 180 pF1KB5 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD :::::. .:::::::.:::: :::::::::::::::::::::::::::::::::: ::.. NP_001 AGAAEKGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 80 90 100 110 120 130 190 200 210 220 230 240 pF1KB5 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI :::.:::::: :::::: ::::::::::::::::::::::.:::::.: ::. ::: .:. NP_001 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV 140 150 160 170 180 190 250 260 270 280 290 300 pF1KB5 VIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDD :::::::::::::.:::::::::: ::.:.:::..:: ::..:...:::::::::::::: NP_001 VIGMDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDD 200 210 220 230 240 250 310 320 330 340 350 360 pF1KB5 WAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLA ::.:..: ..:.:::::::::::::::: .:::.::::::::::::::::::.::::::: NP_001 WATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLA 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB5 QENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDE : ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::. NP_001 QSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDK 320 330 340 350 360 370 430 pF1KB5 ARFAGHNFRNPSVL : :::..:::: NP_001 AIFAGRKFRNPKAK 380 390 434 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:25:54 2016 done: Sat Nov 5 06:25:55 2016 Total Scan time: 7.340 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]