FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5188, 422 aa 1>>>pF1KB5188 422 - 422 aa - 422 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5493+/-0.00039; mu= 17.4679+/- 0.025 mean_var=154.3137+/-38.742, 0's: 0 Z-trim(115.2): 637 B-trim: 1179 in 1/53 Lambda= 0.103246 statistics sampled from 24748 (25546) to 24748 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.3), width: 16 Scan time: 8.590 The best scores are: opt bits E(85289) NP_005288 (OMIM: 601751) melanin-concentrating hor ( 422) 2829 433.8 3.9e-121 NP_115892 (OMIM: 606111) melanin-concentrating hor ( 340) 733 121.5 3.3e-27 NP_001035269 (OMIM: 606111) melanin-concentrating ( 340) 733 121.5 3.3e-27 NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 674 112.7 1.5e-24 NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 666 111.6 3.6e-24 NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 659 110.5 7.5e-24 XP_011528651 (OMIM: 182453) PREDICTED: somatostati ( 418) 659 110.6 7.8e-24 NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 659 110.6 7.8e-24 XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 659 110.6 7.8e-24 XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 659 110.6 7.8e-24 XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 659 110.6 7.8e-24 NP_001042 (OMIM: 182453) somatostatin receptor typ ( 418) 659 110.6 7.8e-24 XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 659 110.6 7.8e-24 NP_001044 (OMIM: 182455) somatostatin receptor typ ( 364) 632 106.5 1.2e-22 NP_001166031 (OMIM: 182455) somatostatin receptor ( 364) 632 106.5 1.2e-22 NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 604 102.3 2.1e-21 NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 592 100.5 7.6e-21 NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 592 100.5 7.6e-21 NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 592 100.6 7.7e-21 NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 592 100.6 7.7e-21 NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 592 100.6 7.7e-21 NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 592 100.6 7.8e-21 NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 592 100.6 7.8e-21 NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 592 100.6 7.9e-21 NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 592 100.6 7.9e-21 NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446) 592 100.6 8.2e-21 NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 592 100.7 8.7e-21 NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 592 100.7 8.7e-21 NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 578 98.4 3.2e-20 NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 578 98.5 3.3e-20 NP_005276 (OMIM: 600730) neuropeptides B/W recepto ( 328) 572 97.5 5.4e-20 NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 550 94.3 5.6e-19 XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 550 94.3 5.6e-19 NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 550 94.3 5.6e-19 NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 550 94.3 5.6e-19 XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 550 94.3 5.8e-19 XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 550 94.3 5.8e-19 XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 550 94.3 5.8e-19 NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 550 94.3 5.9e-19 NP_005277 (OMIM: 600731) neuropeptides B/W recepto ( 333) 535 92.0 2.5e-18 NP_001138753 (OMIM: 600018) mu-type opioid recepto ( 319) 499 86.6 1e-16 NP_001272456 (OMIM: 600018) mu-type opioid recepto ( 292) 495 85.9 1.4e-16 NP_001138752 (OMIM: 600018) mu-type opioid recepto ( 300) 495 85.9 1.5e-16 XP_016866395 (OMIM: 600018) PREDICTED: mu-type opi ( 300) 495 85.9 1.5e-16 NP_001272455 (OMIM: 600018) mu-type opioid recepto ( 300) 495 85.9 1.5e-16 NP_001138759 (OMIM: 600018) mu-type opioid recepto ( 300) 495 85.9 1.5e-16 NP_001272457 (OMIM: 600018) mu-type opioid recepto ( 314) 495 86.0 1.5e-16 XP_016866394 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 495 86.0 1.6e-16 XP_011534153 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 495 86.0 1.6e-16 XP_011534164 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 495 86.0 1.6e-16 >>NP_005288 (OMIM: 601751) melanin-concentrating hormone (422 aa) initn: 2829 init1: 2829 opt: 2829 Z-score: 2295.7 bits: 433.8 E(85289): 3.9e-121 Smith-Waterman score: 2829; 99.8% identity (100.0% similar) in 422 aa overlap (1-422:1-422) 10 20 30 40 50 60 pF1KB5 MSVGAMKKGVGRAVGLGGGSGCQATEEDPLPDCGACAPGQGGRRWRLPQPAWVEGSSARL :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: NP_005 MSVGAMKKGVGRAVGLGGGSGCQATEEDPLPNCGACAPGQGGRRWRLPQPAWVEGSSARL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WEQATGTGWMDLEASLLPTGPNASNTSDGPDNLTSAGSPPRTGSISYINIIMPSVFGTIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 WEQATGTGWMDLEASLLPTGPNASNTSDGPDNLTSAGSPPRTGSISYINIIMPSVFGTIC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LLGIIGNSTVIFAVVKKSKLHWCNNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LLGIIGNSTVIFAVVKKSKLHWCNNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 GETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSVATLVICLLWALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSVATLVICLLWALS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 FISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 FISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVRI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 LQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 LYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRAVSNAQTADEERTESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRAVSNAQTADEERTESK 370 380 390 400 410 420 pF1KB5 GT :: NP_005 GT >>NP_115892 (OMIM: 606111) melanin-concentrating hormone (340 aa) initn: 683 init1: 399 opt: 733 Z-score: 609.4 bits: 121.5 E(85289): 3.3e-27 Smith-Waterman score: 733; 37.9% identity (70.6% similar) in 306 aa overlap (110-408:35-334) 80 90 100 110 120 130 pF1KB5 GPNASNTSDGPDNLTSAGSPPRTGSISYINIIMPSVFGTICLLGIIGNSTVIFAVVKKSK .:.::..: :: :..:: ..:..... : NP_115 HASCWNTSAELLNKSWNKEFAYQTASVVDTVILPSMIGIICSTGLVGNILIVFTIIRSRK 10 20 30 40 50 60 140 150 160 170 180 190 pF1KB5 LHWCNNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTS ..::::.: ::.:.::. ..::::.::: .: : :: .::.::..:. .::. NP_115 ----KTVPDIYICNLAVADLVHIVGMPFLIHQWARGGEWVFGGPLCTIITSLDTCNQFAC 70 80 90 100 110 120 200 210 220 230 240 250 pF1KB5 TYILTAMAIDRYLATVHPISSTKFRKPSVATLVICL-LWALSFISITPVWLYARLIPFPG . :.:.:..:::.: :.:. :..: :. : : ::: ::: :::.:...: : NP_115 SAIMTVMSVDRYFALVQPFRLTRWRT-RYKTIRINLGLWAASFILALPVWVYSKVIKFKD 130 140 150 160 170 260 270 280 290 300 310 pF1KB5 GAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVRIL-----QRMTSSVAPASQ :. .:.. : .:: :. :.::: . .: .:. .: . :. :: . . .. : . NP_115 GVESCAFDLTSPD-DVLWYTLYLTITTFFFPLPLILVCYILILCYTWEMYQQNKDARCCN 180 190 200 210 220 230 320 330 340 350 360 370 pF1KB5 RSI-RLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYAN :. . :. ..:. .... .::.. :::.:.::..:.. .:::.: : .: :.::. NP_115 PSVPKQRVMKLTKMVLVLVVVFILSAAPYHVIQLVNLQMEQPTLAFYVGYYLSICLSYAS 240 250 260 270 280 290 380 390 400 410 420 pF1KB5 SCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRAVSNAQTADEERTESKGT : .:::.::.: .:.::: . :.. .. ..: NP_115 SSINPFLYILLSGNFQKRLPQIQRRATEKEINNMGNTLKSHF 300 310 320 330 340 >>NP_001035269 (OMIM: 606111) melanin-concentrating horm (340 aa) initn: 683 init1: 399 opt: 733 Z-score: 609.4 bits: 121.5 E(85289): 3.3e-27 Smith-Waterman score: 733; 37.9% identity (70.6% similar) in 306 aa overlap (110-408:35-334) 80 90 100 110 120 130 pF1KB5 GPNASNTSDGPDNLTSAGSPPRTGSISYINIIMPSVFGTICLLGIIGNSTVIFAVVKKSK .:.::..: :: :..:: ..:..... : NP_001 HASCWNTSAELLNKSWNKEFAYQTASVVDTVILPSMIGIICSTGLVGNILIVFTIIRSRK 10 20 30 40 50 60 140 150 160 170 180 190 pF1KB5 LHWCNNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTS ..::::.: ::.:.::. ..::::.::: .: : :: .::.::..:. .::. NP_001 ----KTVPDIYICNLAVADLVHIVGMPFLIHQWARGGEWVFGGPLCTIITSLDTCNQFAC 70 80 90 100 110 120 200 210 220 230 240 250 pF1KB5 TYILTAMAIDRYLATVHPISSTKFRKPSVATLVICL-LWALSFISITPVWLYARLIPFPG . :.:.:..:::.: :.:. :..: :. : : ::: ::: :::.:...: : NP_001 SAIMTVMSVDRYFALVQPFRLTRWRT-RYKTIRINLGLWAASFILALPVWVYSKVIKFKD 130 140 150 160 170 260 270 280 290 300 310 pF1KB5 GAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVRIL-----QRMTSSVAPASQ :. .:.. : .:: :. :.::: . .: .:. .: . :. :: . . .. : . NP_001 GVESCAFDLTSPD-DVLWYTLYLTITTFFFPLPLILVCYILILCYTWEMYQQNKDARCCN 180 190 200 210 220 230 320 330 340 350 360 370 pF1KB5 RSI-RLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYAN :. . :. ..:. .... .::.. :::.:.::..:.. .:::.: : .: :.::. NP_001 PSVPKQRVMKLTKMVLVLVVVFILSAAPYHVIQLVNLQMEQPTLAFYVGYYLSICLSYAS 240 250 260 270 280 290 380 390 400 410 420 pF1KB5 SCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRAVSNAQTADEERTESKGT : .:::.::.: .:.::: . :.. .. ..: NP_001 SSINPFLYILLSGNFQKRLPQIQRRATEKEINNMGNTLKSHF 300 310 320 330 340 >>NP_001041 (OMIM: 182452) somatostatin receptor type 2 (369 aa) initn: 539 init1: 248 opt: 674 Z-score: 561.5 bits: 112.7 E(85289): 1.5e-24 Smith-Waterman score: 678; 32.4% identity (65.3% similar) in 352 aa overlap (71-420:20-344) 50 60 70 80 90 100 pF1KB5 GGRRWRLPQPAWVEGSSARLWEQATGTGWMDLEASLLPTGPNASNTSDGPDNLTSAGSPP ::..:.. : :.:: .. .::: NP_001 MDMADEPLNGSHTWLSIPFDLNGSVVST--NTSNQTEPYYDLTS----- 10 20 30 40 110 120 130 140 150 160 pF1KB5 RTGSISYINIIMPSVFGTICLLGIIGNSTVIFAVVKKSKLHWCNNVPDIFIINLSVVDLL : .. .. ..:..:. ::. ::..... .:. ... .:.:.::...: : NP_001 --------NAVLTFIYFVVCIIGLCGNTLVIYVILRYAKM---KTITNIYILNLAIADEL 50 60 70 80 90 170 180 190 200 210 220 pF1KB5 FLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISS :.::.::. :. : ::...: .. ..:. .:::: . ::.:.::::::.::::.: NP_001 FMLGLPFLAMQVALVH-WPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKS 100 110 120 130 140 150 230 240 250 260 270 pF1KB5 TKFRKPSVATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYW-FTL .:.:.: .: .. .:..:.. : :. .:: : : .: : :. . : : . NP_001 AKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFII 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB5 YQFFLAFALPFVVITAAYVRILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWA : :.:.: .:...: :. :. .. :: ... . . :.::: . . ::. :: NP_001 YTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWL 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB5 PYYVLQLTQLSIS-RPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPA :.:.......:.. :: .. ... .. : ::::: ::..: : ..:.: . NP_001 PFYIFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSF------- 280 290 300 310 320 400 410 420 pF1KB5 AQGQLRAVSNAQTADEERTESKGT :. : :. . : : ::..:: NP_001 -QNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI 330 340 350 360 >>NP_001040 (OMIM: 182451) somatostatin receptor type 1 (391 aa) initn: 571 init1: 293 opt: 666 Z-score: 554.8 bits: 111.6 E(85289): 3.6e-24 Smith-Waterman score: 666; 33.3% identity (67.6% similar) in 312 aa overlap (80-389:29-332) 50 60 70 80 90 100 pF1KB5 PAWVEGSSARLWEQATGTGWMDLEASLLPTGPNASNTSDGPDNLTSAGSPPRTGSISYIN ::.:. ..:: .. .: : : . . NP_001 MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAG-AADGMEEPGRNASQNGTLSEGQGS 10 20 30 40 50 110 120 130 140 150 160 pF1KB5 IIMPS-VFGTICLLGIIGNSTVIFAVVKKSKLHWCNNVPDIFIINLSVVDLLFLLGMPFM :. : .....::.:. ::: ::..... .:.. .: :.:.::...: :..:..::. NP_001 AILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATN---IYILNLAIADELLMLSVPFL 60 70 80 90 100 110 170 180 190 200 210 220 pF1KB5 IHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSV . . . : :: .: :. ..:: ..::: : ::....:::.:.::::.....:.:.: NP_001 VTSTLLRH-WPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTV 120 130 140 150 160 170 230 240 250 260 270 280 pF1KB5 ATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTD-LYWFTLYQFFLAFA : .: .:.::.. : :. ...: :.:.:.. .:.: : :.:: :...: NP_001 AKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFL 180 190 200 210 220 230 290 300 310 320 330 340 pF1KB5 LPFVVITAAYVRILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLT :: .: :: :. .: . :. .. . ...: .. . .:: .:: :.::.::. NP_001 LPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLV 240 250 260 270 280 290 350 360 370 380 390 400 pF1KB5 QLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRAVS .. . : : .. ::::::: ::..: : ..:.. NP_001 NVFAEQDDATVSQL---SVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEP 300 310 320 330 340 350 410 420 pF1KB5 NAQTADEERTESKGT NP_001 VDYYATALKSRAYSVEDFQPENLESGGVFRNGTCTSRITTL 360 370 380 390 >>NP_001043 (OMIM: 182454) somatostatin receptor type 4 (388 aa) initn: 575 init1: 377 opt: 659 Z-score: 549.2 bits: 110.5 E(85289): 7.5e-24 Smith-Waterman score: 660; 31.9% identity (66.0% similar) in 329 aa overlap (62-389:12-320) 40 50 60 70 80 90 pF1KB5 DCGACAPGQGGRRWRLPQPAWVEGSSARLWEQATGTGWMDLEASLLPTGPNASNTSDGPD :.. ::.: :.:.:.:..: NP_001 MSAPSTLPPGGEEGLGTAW-----------PSAANASSAPA 10 20 30 100 110 120 130 140 150 pF1KB5 NLTSAGSPPRTGSISYINIIMPSVFGTICLLGIIGNSTVIFAVVKKSKLHWCNNVPDIFI . : . : . . . . . ... .::.:..::. :::.... .:.. .: :.. NP_001 EAEEAVAGPGDARAAGM-VAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATN---IYL 40 50 60 70 80 160 170 180 190 200 210 pF1KB5 INLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMAIDRY .::.:.: ::.:..::. . : :: ..: . ..:. ..:::.. ::....::: NP_001 LNLAVADELFMLSVPFVASSAALRH-WPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRY 90 100 110 120 130 140 220 230 240 250 260 270 pF1KB5 LATVHPISSTKFRKPSVATLVICLLWALSFISITPVWLYARLIPFPGG-AVGCGIRLPNP .:.:::. .. .:.:::: :. .: :.. :. ..: : :: ::.:... :.: NP_001 VAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHP 150 160 170 180 190 200 280 290 300 310 320 330 pF1KB5 DTDLYWFTLYQFFLAFALPFVVITAAYVRILQRMTSSVAPASQRSIRLRTKRVTRTAIAI . :..: :.:.: :: ..: :. :. .: . . :. .. : :..:: .. . NP_001 AWSAV-FVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMV 210 220 230 240 250 260 340 350 360 370 380 390 pF1KB5 CLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKR .:: .:: :.::.:: .: .. : . .... :.::::: ::..: : ..::. NP_001 VVVFVLCWMPFYVVQLLNLFVTSLDAT---VNHVSLILSYANSCANPILYGFLSDNFRRF 270 280 290 300 310 320 400 410 420 pF1KB5 LVLSVKPAAQGQLRAVSNAQTADEERTESKGT NP_001 FQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIP 330 340 350 360 370 380 >>XP_011528651 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 542 init1: 229 opt: 659 Z-score: 548.9 bits: 110.6 E(85289): 7.8e-24 Smith-Waterman score: 659; 32.6% identity (62.1% similar) in 359 aa overlap (81-418:6-354) 60 70 80 90 100 pF1KB5 AWVEGSSARLWEQATGTGWMDLEASLLPTGPNASNTSDGPDNLTSAGSP----------P :.. .:.. :.: .:: : : XP_011 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGP 10 20 30 110 120 130 140 150 160 pF1KB5 RTGSISYINIIMPSVFGTICLLGIIGNSTVIFAVVKKSKLHWCNNVPDIFIINLSVVDLL .... ....: :. ..:..:..::: ::..:.... .: ...:.::...: : XP_011 SPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTA---SPSVTNVYILNLALADEL 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB5 FLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISS :.::.::. : . . : :: :: :. :.:. .:::: . ::.:..:::::.::: : XP_011 FMLGLPFLAAQ-NALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRS 100 110 120 130 140 150 230 240 250 260 270 pF1KB5 TKFRKPSVATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYW---F ...: :: : .:. : . . :: ... . : : : .. :.: . : : XP_011 ARWRTAPVARTVSAAVWVASAVVVLPVVVFSGV---PRGMSTCHMQWPEPAAA--WRAGF 160 170 180 190 200 280 290 300 310 320 330 pF1KB5 TLYQFFLAFALPFVVITAAYVRILQRMTSS----VAPASQRSIRLRTKRVTRTAIAICLV .: :.: :..:: :. :. .. :. ::. :: : .:::: ..:. . XP_011 IIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRR-RRSERRVTRMVVAVVAL 210 220 230 240 250 260 340 350 360 370 380 pF1KB5 FFVCWAPYYVLQLTQLSISRPTL-TFVYLYNAAISLGYANSCLNPFVYIVLCETFR---K : .:: :.:::..... : .: :: ...: ::::: ::..: : :. . XP_011 FVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFR 270 280 290 300 310 320 390 400 410 420 pF1KB5 RLVLSVKPAAQGQLRAVSNAQTADEERTESKGT :..: . ...: .:. . ..:: : XP_011 RVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQ 330 340 350 360 370 380 >>NP_001265616 (OMIM: 182453) somatostatin receptor type (418 aa) initn: 542 init1: 229 opt: 659 Z-score: 548.9 bits: 110.6 E(85289): 7.8e-24 Smith-Waterman score: 659; 32.6% identity (62.1% similar) in 359 aa overlap (81-418:6-354) 60 70 80 90 100 pF1KB5 AWVEGSSARLWEQATGTGWMDLEASLLPTGPNASNTSDGPDNLTSAGSP----------P :.. .:.. :.: .:: : : NP_001 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGP 10 20 30 110 120 130 140 150 160 pF1KB5 RTGSISYINIIMPSVFGTICLLGIIGNSTVIFAVVKKSKLHWCNNVPDIFIINLSVVDLL .... ....: :. ..:..:..::: ::..:.... .: ...:.::...: : NP_001 SPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTA---SPSVTNVYILNLALADEL 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB5 FLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISS :.::.::. : . . : :: :: :. :.:. .:::: . ::.:..:::::.::: : NP_001 FMLGLPFLAAQ-NALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRS 100 110 120 130 140 150 230 240 250 260 270 pF1KB5 TKFRKPSVATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYW---F ...: :: : .:. : . . :: ... . : : : .. :.: . : : NP_001 ARWRTAPVARTVSAAVWVASAVVVLPVVVFSGV---PRGMSTCHMQWPEPAAA--WRAGF 160 170 180 190 200 280 290 300 310 320 330 pF1KB5 TLYQFFLAFALPFVVITAAYVRILQRMTSS----VAPASQRSIRLRTKRVTRTAIAICLV .: :.: :..:: :. :. .. :. ::. :: : .:::: ..:. . NP_001 IIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRR-RRSERRVTRMVVAVVAL 210 220 230 240 250 260 340 350 360 370 380 pF1KB5 FFVCWAPYYVLQLTQLSISRPTL-TFVYLYNAAISLGYANSCLNPFVYIVLCETFR---K : .:: :.:::..... : .: :: ...: ::::: ::..: : :. . NP_001 FVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFR 270 280 290 300 310 320 390 400 410 420 pF1KB5 RLVLSVKPAAQGQLRAVSNAQTADEERTESKGT :..: . ...: .:. . ..:: : NP_001 RVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQ 330 340 350 360 370 380 >>XP_005261778 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 542 init1: 229 opt: 659 Z-score: 548.9 bits: 110.6 E(85289): 7.8e-24 Smith-Waterman score: 659; 32.6% identity (62.1% similar) in 359 aa overlap (81-418:6-354) 60 70 80 90 100 pF1KB5 AWVEGSSARLWEQATGTGWMDLEASLLPTGPNASNTSDGPDNLTSAGSP----------P :.. .:.. :.: .:: : : XP_005 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGP 10 20 30 110 120 130 140 150 160 pF1KB5 RTGSISYINIIMPSVFGTICLLGIIGNSTVIFAVVKKSKLHWCNNVPDIFIINLSVVDLL .... ....: :. ..:..:..::: ::..:.... .: ...:.::...: : XP_005 SPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTA---SPSVTNVYILNLALADEL 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB5 FLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISS :.::.::. : . . : :: :: :. :.:. .:::: . ::.:..:::::.::: : XP_005 FMLGLPFLAAQ-NALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRS 100 110 120 130 140 150 230 240 250 260 270 pF1KB5 TKFRKPSVATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYW---F ...: :: : .:. : . . :: ... . : : : .. :.: . : : XP_005 ARWRTAPVARTVSAAVWVASAVVVLPVVVFSGV---PRGMSTCHMQWPEPAAA--WRAGF 160 170 180 190 200 280 290 300 310 320 330 pF1KB5 TLYQFFLAFALPFVVITAAYVRILQRMTSS----VAPASQRSIRLRTKRVTRTAIAICLV .: :.: :..:: :. :. .. :. ::. :: : .:::: ..:. . XP_005 IIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRR-RRSERRVTRMVVAVVAL 210 220 230 240 250 260 340 350 360 370 380 pF1KB5 FFVCWAPYYVLQLTQLSISRPTL-TFVYLYNAAISLGYANSCLNPFVYIVLCETFR---K : .:: :.:::..... : .: :: ...: ::::: ::..: : :. . XP_005 FVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFR 270 280 290 300 310 320 390 400 410 420 pF1KB5 RLVLSVKPAAQGQLRAVSNAQTADEERTESKGT :..: . ...: .:. . ..:: : XP_005 RVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQ 330 340 350 360 370 380 >>XP_016884413 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 542 init1: 229 opt: 659 Z-score: 548.9 bits: 110.6 E(85289): 7.8e-24 Smith-Waterman score: 659; 32.6% identity (62.1% similar) in 359 aa overlap (81-418:6-354) 60 70 80 90 100 pF1KB5 AWVEGSSARLWEQATGTGWMDLEASLLPTGPNASNTSDGPDNLTSAGSP----------P :.. .:.. :.: .:: : : XP_016 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGP 10 20 30 110 120 130 140 150 160 pF1KB5 RTGSISYINIIMPSVFGTICLLGIIGNSTVIFAVVKKSKLHWCNNVPDIFIINLSVVDLL .... ....: :. ..:..:..::: ::..:.... .: ...:.::...: : XP_016 SPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTA---SPSVTNVYILNLALADEL 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB5 FLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISS :.::.::. : . . : :: :: :. :.:. .:::: . ::.:..:::::.::: : XP_016 FMLGLPFLAAQ-NALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRS 100 110 120 130 140 150 230 240 250 260 270 pF1KB5 TKFRKPSVATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYW---F ...: :: : .:. : . . :: ... . : : : .. :.: . : : XP_016 ARWRTAPVARTVSAAVWVASAVVVLPVVVFSGV---PRGMSTCHMQWPEPAAA--WRAGF 160 170 180 190 200 280 290 300 310 320 330 pF1KB5 TLYQFFLAFALPFVVITAAYVRILQRMTSS----VAPASQRSIRLRTKRVTRTAIAICLV .: :.: :..:: :. :. .. :. ::. :: : .:::: ..:. . XP_016 IIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRR-RRSERRVTRMVVAVVAL 210 220 230 240 250 260 340 350 360 370 380 pF1KB5 FFVCWAPYYVLQLTQLSISRPTL-TFVYLYNAAISLGYANSCLNPFVYIVLCETFR---K : .:: :.:::..... : .: :: ...: ::::: ::..: : :. . XP_016 FVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFR 270 280 290 300 310 320 390 400 410 420 pF1KB5 RLVLSVKPAAQGQLRAVSNAQTADEERTESKGT :..: . ...: .:. . ..:: : XP_016 RVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQ 330 340 350 360 370 380 422 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:25:32 2016 done: Fri Nov 4 03:25:33 2016 Total Scan time: 8.590 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]