FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5205, 543 aa 1>>>pF1KB5205 543 - 543 aa - 543 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1992+/-0.000483; mu= 19.1557+/- 0.030 mean_var=69.0806+/-14.127, 0's: 0 Z-trim(107.9): 61 B-trim: 29 in 1/50 Lambda= 0.154311 statistics sampled from 15963 (16016) to 15963 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.533), E-opt: 0.2 (0.188), width: 16 Scan time: 9.500 The best scores are: opt bits E(85289) NP_006420 (OMIM: 605140) T-complex protein 1 subun ( 543) 3495 787.9 0 NP_001159757 (OMIM: 605140) T-complex protein 1 su ( 499) 3213 725.1 1.2e-208 XP_011530780 (OMIM: 605140) PREDICTED: T-complex p ( 499) 3213 725.1 1.2e-208 XP_011530781 (OMIM: 605140) PREDICTED: T-complex p ( 499) 3213 725.1 1.2e-208 NP_001159756 (OMIM: 605140) T-complex protein 1 su ( 456) 2937 663.7 3.5e-190 NP_001009570 (OMIM: 605140) T-complex protein 1 su ( 339) 2226 505.3 1.2e-142 NP_006422 (OMIM: 605139) T-complex protein 1 subun ( 535) 1012 235.2 4e-61 NP_006421 (OMIM: 605142) T-complex protein 1 subun ( 539) 1005 233.6 1.2e-60 NP_005989 (OMIM: 600114) T-complex protein 1 subun ( 545) 987 229.6 1.9e-59 NP_001185771 (OMIM: 605139) T-complex protein 1 su ( 488) 934 217.8 6.3e-56 NP_110379 (OMIM: 186980) T-complex protein 1 subun ( 556) 903 210.9 8.4e-54 NP_036205 (OMIM: 256840,610150) T-complex protein ( 541) 895 209.1 2.8e-53 NP_001293082 (OMIM: 256840,610150) T-complex prote ( 520) 883 206.4 1.7e-52 NP_001293085 (OMIM: 256840,610150) T-complex prote ( 503) 866 202.6 2.3e-51 NP_001008800 (OMIM: 600114) T-complex protein 1 su ( 507) 832 195.1 4.5e-49 NP_001243650 (OMIM: 605142) T-complex protein 1 su ( 509) 762 179.5 2.2e-44 NP_001753 (OMIM: 104613) T-complex protein 1 subun ( 531) 716 169.3 2.8e-41 NP_006575 (OMIM: 610730) T-complex protein 1 subun ( 530) 675 160.1 1.5e-38 NP_001293083 (OMIM: 256840,610150) T-complex prote ( 486) 599 143.2 1.8e-33 NP_001293084 (OMIM: 256840,610150) T-complex prote ( 448) 595 142.3 3.1e-33 NP_001008897 (OMIM: 186980) T-complex protein 1 su ( 401) 580 138.9 2.9e-32 XP_016879512 (OMIM: 610730) PREDICTED: T-complex p ( 464) 566 135.8 2.8e-31 NP_001009186 (OMIM: 104613) T-complex protein 1 su ( 486) 481 116.9 1.4e-25 NP_001180459 (OMIM: 610730) T-complex protein 1 su ( 485) 446 109.1 3.2e-23 XP_016879513 (OMIM: 610730) PREDICTED: T-complex p ( 351) 404 99.7 1.6e-20 XP_011522505 (OMIM: 610730) PREDICTED: T-complex p ( 388) 404 99.7 1.7e-20 NP_001180458 (OMIM: 610730) T-complex protein 1 su ( 493) 404 99.8 2.1e-20 NP_955472 (OMIM: 118190,605280,612233) 60 kDa heat ( 573) 198 54.0 1.5e-06 NP_002147 (OMIM: 118190,605280,612233) 60 kDa heat ( 573) 198 54.0 1.5e-06 XP_011509094 (OMIM: 121850,609414) PREDICTED: 1-ph (1340) 194 53.3 5.6e-06 XP_011509092 (OMIM: 121850,609414) PREDICTED: 1-ph (1779) 194 53.4 7e-06 XP_016859061 (OMIM: 121850,609414) PREDICTED: 1-ph (1779) 194 53.4 7e-06 XP_016859062 (OMIM: 121850,609414) PREDICTED: 1-ph (1779) 194 53.4 7e-06 XP_016859063 (OMIM: 121850,609414) PREDICTED: 1-ph (1779) 194 53.4 7e-06 XP_011509091 (OMIM: 121850,609414) PREDICTED: 1-ph (1951) 194 53.4 7.5e-06 XP_011509090 (OMIM: 121850,609414) PREDICTED: 1-ph (2001) 194 53.4 7.7e-06 XP_011509089 (OMIM: 121850,609414) PREDICTED: 1-ph (2012) 194 53.4 7.7e-06 XP_011509088 (OMIM: 121850,609414) PREDICTED: 1-ph (2013) 194 53.4 7.7e-06 XP_011509084 (OMIM: 121850,609414) PREDICTED: 1-ph (2055) 194 53.4 7.8e-06 XP_016859057 (OMIM: 121850,609414) PREDICTED: 1-ph (2092) 194 53.4 8e-06 NP_055855 (OMIM: 121850,609414) 1-phosphatidylinos (2098) 194 53.4 8e-06 XP_011509083 (OMIM: 121850,609414) PREDICTED: 1-ph (2104) 194 53.4 8e-06 XP_011509082 (OMIM: 121850,609414) PREDICTED: 1-ph (2109) 194 53.4 8e-06 XP_011509081 (OMIM: 121850,609414) PREDICTED: 1-ph (2110) 194 53.4 8e-06 XP_011509080 (OMIM: 121850,609414) PREDICTED: 1-ph (2110) 194 53.4 8e-06 XP_016859060 (OMIM: 121850,609414) PREDICTED: 1-ph (1895) 193 53.2 8.6e-06 XP_016859059 (OMIM: 121850,609414) PREDICTED: 1-ph (1945) 193 53.2 8.8e-06 XP_011509086 (OMIM: 121850,609414) PREDICTED: 1-ph (2053) 193 53.2 9.1e-06 XP_011509085 (OMIM: 121850,609414) PREDICTED: 1-ph (2054) 193 53.2 9.1e-06 XP_016859058 (OMIM: 121850,609414) PREDICTED: 1-ph (2036) 189 52.3 1.7e-05 >>NP_006420 (OMIM: 605140) T-complex protein 1 subunit e (543 aa) initn: 3495 init1: 3495 opt: 3495 Z-score: 4205.6 bits: 787.9 E(85289): 0 Smith-Waterman score: 3495; 100.0% identity (100.0% similar) in 543 aa overlap (1-543:1-543) 10 20 30 40 50 60 pF1KB5 MMPTPVILLKEGTDSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MMPTPVILLKEGTDSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DGATILKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DGATILKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 IIRAFRTATQLAVNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 IIRAFRTATQLAVNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 DAVMMLDDLLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DAVMMLDDLLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 NVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 NVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVAT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 QYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 FTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 FTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 RDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDIN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 NEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIKNPRSTVDAPTAAGRGRGRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 NEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIKNPRSTVDAPTAAGRGRGRG 490 500 510 520 530 540 pF1KB5 RPH ::: NP_006 RPH >>NP_001159757 (OMIM: 605140) T-complex protein 1 subuni (499 aa) initn: 3213 init1: 3213 opt: 3213 Z-score: 3866.9 bits: 725.1 E(85289): 1.2e-208 Smith-Waterman score: 3213; 100.0% identity (100.0% similar) in 499 aa overlap (45-543:1-499) 20 30 40 50 60 70 pF1KB5 SSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGATILKLLDVVHP :::::::::::::::::::::::::::::: NP_001 MDKLIVDGRGKATISNDGATILKLLDVVHP 10 20 30 80 90 100 110 120 130 pF1KB5 AAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAVN 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB5 KIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLDDLLQLKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLDDLLQLKM 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB5 IGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELKAEKDNAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELKAEKDNAE 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB5 IRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCAGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCAGRV 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB5 PEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNFFTGCPKAKTCTFIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNFFTGCPKAKTCTFIL 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB5 RGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLL 340 350 360 370 380 390 440 450 460 470 480 490 pF1KB5 IGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAFVWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAFVWE 400 410 420 430 440 450 500 510 520 530 540 pF1KB5 PAMVRINALTAASEAACLIVSVDETIKNPRSTVDAPTAAGRGRGRGRPH ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAMVRINALTAASEAACLIVSVDETIKNPRSTVDAPTAAGRGRGRGRPH 460 470 480 490 >>XP_011530780 (OMIM: 605140) PREDICTED: T-complex prote (499 aa) initn: 3213 init1: 3213 opt: 3213 Z-score: 3866.9 bits: 725.1 E(85289): 1.2e-208 Smith-Waterman score: 3213; 100.0% identity (100.0% similar) in 499 aa overlap (45-543:1-499) 20 30 40 50 60 70 pF1KB5 SSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGATILKLLDVVHP :::::::::::::::::::::::::::::: XP_011 MDKLIVDGRGKATISNDGATILKLLDVVHP 10 20 30 80 90 100 110 120 130 pF1KB5 AAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAVN 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB5 KIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLDDLLQLKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLDDLLQLKM 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB5 IGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELKAEKDNAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELKAEKDNAE 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB5 IRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCAGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCAGRV 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB5 PEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNFFTGCPKAKTCTFIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNFFTGCPKAKTCTFIL 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB5 RGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLL 340 350 360 370 380 390 440 450 460 470 480 490 pF1KB5 IGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAFVWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAFVWE 400 410 420 430 440 450 500 510 520 530 540 pF1KB5 PAMVRINALTAASEAACLIVSVDETIKNPRSTVDAPTAAGRGRGRGRPH ::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAMVRINALTAASEAACLIVSVDETIKNPRSTVDAPTAAGRGRGRGRPH 460 470 480 490 >>XP_011530781 (OMIM: 605140) PREDICTED: T-complex prote (499 aa) initn: 3213 init1: 3213 opt: 3213 Z-score: 3866.9 bits: 725.1 E(85289): 1.2e-208 Smith-Waterman score: 3213; 100.0% identity (100.0% similar) in 499 aa overlap (45-543:1-499) 20 30 40 50 60 70 pF1KB5 SSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGATILKLLDVVHP :::::::::::::::::::::::::::::: XP_011 MDKLIVDGRGKATISNDGATILKLLDVVHP 10 20 30 80 90 100 110 120 130 pF1KB5 AAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAVN 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB5 KIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLDDLLQLKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLDDLLQLKM 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB5 IGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELKAEKDNAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELKAEKDNAE 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB5 IRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCAGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCAGRV 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB5 PEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNFFTGCPKAKTCTFIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNFFTGCPKAKTCTFIL 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB5 RGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLL 340 350 360 370 380 390 440 450 460 470 480 490 pF1KB5 IGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAFVWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAFVWE 400 410 420 430 440 450 500 510 520 530 540 pF1KB5 PAMVRINALTAASEAACLIVSVDETIKNPRSTVDAPTAAGRGRGRGRPH ::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAMVRINALTAASEAACLIVSVDETIKNPRSTVDAPTAAGRGRGRGRPH 460 470 480 490 >>NP_001159756 (OMIM: 605140) T-complex protein 1 subuni (456 aa) initn: 2937 init1: 2937 opt: 2937 Z-score: 3535.4 bits: 663.7 E(85289): 3.5e-190 Smith-Waterman score: 2937; 100.0% identity (100.0% similar) in 454 aa overlap (90-543:3-456) 60 70 80 90 100 110 pF1KB5 NDGATILKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQ :::::::::::::::::::::::::::::: NP_001 MMVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQ 10 20 30 120 130 140 150 160 170 pF1KB5 IIIRAFRTATQLAVNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIIRAFRTATQLAVNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMV 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB5 VDAVMMLDDLLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDAVMMLDDLLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIAL 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB5 LNVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVA 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB5 TQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYN 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB5 FFTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FFTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKY 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB5 LRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDI 340 350 360 370 380 390 480 490 500 510 520 530 pF1KB5 NNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIKNPRSTVDAPTAAGRGRGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIKNPRSTVDAPTAAGRGRGR 400 410 420 430 440 450 540 pF1KB5 GRPH :::: NP_001 GRPH >>NP_001009570 (OMIM: 605140) T-complex protein 1 subuni (339 aa) initn: 2226 init1: 2226 opt: 2226 Z-score: 2681.8 bits: 505.3 E(85289): 1.2e-142 Smith-Waterman score: 2226; 99.4% identity (99.7% similar) in 339 aa overlap (205-543:1-339) 180 190 200 210 220 230 pF1KB5 FAKMVVDAVMMLDDLLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHN . :::::::::::::::::::::::::::: NP_001 MMDSQLVAGVAFKKTFSYAGFEMQPKKYHN 10 20 30 240 250 260 270 280 290 pF1KB5 PKIALLNVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKIALLNVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLP 40 50 60 70 80 90 300 310 320 330 340 350 pF1KB5 IGDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIG 100 110 120 130 140 150 360 370 380 390 400 410 pF1KB5 GERYNFFTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GERYNFFTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEM 160 170 180 190 200 210 420 430 440 450 460 470 pF1KB5 ELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTW 220 230 240 250 260 270 480 490 500 510 520 530 pF1KB5 YGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIKNPRSTVDAPTAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIKNPRSTVDAPTAAG 280 290 300 310 320 330 540 pF1KB5 RGRGRGRPH ::::::::: NP_001 RGRGRGRPH >>NP_006422 (OMIM: 605139) T-complex protein 1 subunit b (535 aa) initn: 897 init1: 455 opt: 1012 Z-score: 1218.3 bits: 235.2 E(85289): 4e-61 Smith-Waterman score: 1012; 35.6% identity (67.2% similar) in 528 aa overlap (5-527:8-529) 10 20 30 40 50 pF1KB5 MMPTPVILLKEGTDSSQG-IPQLVSNISACQVIAEAVRTTLGPRGMDKLIVD-GRGK :: ..: :.: .. .:.: :.: .:.. :..::::.::::.... :: NP_006 MASLSLAPVNIFKAGADEERAETARLTSFIGAI-AIGDLVKSTLGPKGMDKILLSSGRDA 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 AT-ISNDGATILKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEE . ..:::::::: . : .::::.:::... :: ::::::::::.::::.:.... . . NP_006 SLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 GLHPQIIIRAFRTATQLAVNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAF .::: :: ..: ::. : . . :: . .:.:. :. : . : :.:::::....: NP_006 KIHPQTIIAGWREATKAAREALLSSAVD-HGSDEVKFRQDLMNIAGTTLSSKLLTHHKDH 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 FAKMVVDAVMMLDDLLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHN :.:..:.::. : .:. : : : ::.: :: : : . : .. :::. .: NP_006 FTKLAVEAVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVN----QPKRIEN 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 PKIALLNVELEL-KAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKL :: . :. .. : . ....:: .. : :: . . .:.:.: . : . ... NP_006 AKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQ 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 PIGDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQI : . : :. .. .. ..: .. :: : .. . :: :...::..: NP_006 LIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMI 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB5 GGERYNFFTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIE : .. :.: ...::..:::...:...:.:::::::. .. ...:.. .: ::: : NP_006 GEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSE 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB5 MELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGT : ... . . . :::. . . .:::::...: . ::::.:..... .::: :..:.: NP_006 MLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNT 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB5 WYGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIKN-PRSTVDAPTA :.:. . :.: . : .:. ..: .:.::: .:. ::. :: ::. : NP_006 TAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHP 480 490 500 510 520 530 540 pF1KB5 AGRGRGRGRPH NP_006 C >>NP_006421 (OMIM: 605142) T-complex protein 1 subunit d (539 aa) initn: 830 init1: 413 opt: 1005 Z-score: 1209.8 bits: 233.6 E(85289): 1.2e-60 Smith-Waterman score: 1005; 34.4% identity (68.9% similar) in 514 aa overlap (24-524:36-539) 10 20 30 40 50 pF1KB5 MMPTPVILLKEGTDSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGR ::::: ...:.:.::.:::.::::.: ::. NP_006 APRSGATAGAAGGRGKGAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 GKATISNDGATILKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVE : .::.:::::::: ..:.::::. ::...:.:: :.:::::::...:. .: . .. NP_006 GDVTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQ 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 EGLHPQIIIRAFRTATQLAVNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKA .:.:: :: ..:. : . ... . ... :. .: :. : . : :.:.::..:: .. NP_006 KGIHPTIISESFQKALEKGIEILTDMSRPVELSD----RETLLNSATTSLNSKVVSQYSS 130 140 150 160 170 180 180 190 200 210 220 pF1KB5 FFAKMVVDAVMMLDD-----LLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQ ... : :.::: . : ..:. : : : ::...: .:: :... . : .:. NP_006 LLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVSNSGIT-- 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 PKKYHNPKIALLNVELEL-KAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAK . .. ::.:.. : :.. :: .: : ... .. : . . ...:...: . NP_006 --RVEKAKIGLIQFCLSAPKTDMDN-QIVVSDYAQMDRVLREERAYILNLVKQIKKTGCN 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 VVLSKLPI-----GDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVL :.: . : .:.: ... .. . .::.. . : . . .. ..::.: NP_006 VLLIQKSILRDALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQFTADML 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB5 GRCQVFEETQIGGE-RYNFFTGCPK-AKTCTFILRGGAEQFMEETERSLHDAIMIVRRAI : .. ::....: . .::: . .:: :...::. . .::.:::.:::. ..: . NP_006 GSAELAEEVNLNGSGKLLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLV 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB5 KNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNI :. ...::::: :.::. : .::::. : .. . :.: :.:.:: : .:::.. . NP_006 KKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPIST 420 430 440 450 460 470 470 480 490 500 510 520 pF1KB5 LNKLRARHAQGGTWYGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETI ...:: ::::: :... . :.. .: .: .: .: ..::: :.:.. :...:... NP_006 VTELRNRHAQGEKTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILKIDDVV 480 490 500 510 520 530 530 540 pF1KB5 KNPRSTVDAPTAAGRGRGRGRPH : : NP_006 -NTR >>NP_005989 (OMIM: 600114) T-complex protein 1 subunit g (545 aa) initn: 872 init1: 492 opt: 987 Z-score: 1188.1 bits: 229.6 E(85289): 1.9e-59 Smith-Waterman score: 987; 31.7% identity (66.1% similar) in 545 aa overlap (1-534:2-537) 10 20 30 40 50 pF1KB5 MMPTPVILLKEGTDSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATIS : ::..:...: .: .::.: ..::. .:: :::..: :...: : ... NP_005 MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 NDGATILKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQ ::: .::. ..: :::::....:...:: ::::::::: .::.:.:. .. ..:. .:: NP_005 NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 IIIRAFRTATQLAVNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMV ..: :.: : . .. .:.:.. : .:. .. . .....: ::. ... ... NP_005 VVISAYRKALDDMISTLKKISIPVDISDS----DMMLNIINSSITTKAISRWSSLACNIA 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 VDAVMMLD-------DLLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKY .::: :.. .. :. ..:. :: .::: .. :: ..: .. . ..: NP_005 LDAVKMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHP----RMRRY 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 -HNPKIALLNVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLS .::.:.::. :: : .....:.. ::. :.. : . . . : : . ::.. NP_005 IKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVIT 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 KLPIGDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGR-CQVFEE . :.:.: .:. .. :: . : .: :::. : . . : : .: ..: NP_005 EKGISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEI 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB5 TQIGGERYNFFTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGG .:: : ..:.: : :.::..:::...... :.::.:.::... : .. . ..: ::: NP_005 KKIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGG 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB5 AIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQ : :: ... : . :... : .: : :.:::.::: : .: : .. .:..:::.:.: NP_005 ASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQ 420 430 440 450 460 470 480 490 500 510 520 pF1KB5 GG--TWYGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIKNPRSTVD . :: ::. .. ..: : .::: :.... .: :.: :.. .:. ... .. : NP_005 ENCETW-GVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGD 480 490 500 510 520 530 530 540 pF1KB5 APTAAGRGRGRGRPH . : NP_005 DQSRQGGAPDAGQE 540 >>NP_001185771 (OMIM: 605139) T-complex protein 1 subuni (488 aa) initn: 846 init1: 455 opt: 934 Z-score: 1125.0 bits: 217.8 E(85289): 6.3e-56 Smith-Waterman score: 934; 35.3% identity (66.7% similar) in 487 aa overlap (45-527:1-482) 20 30 40 50 60 70 pF1KB5 SSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVD-GRGKAT-ISNDGATILKLLDVV :::.... :: . ..:::::::: . : NP_001 MDKILLSSGRDASLMVTNDGATILKNIGVD 10 20 30 80 90 100 110 120 130 pF1KB5 HPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLA .::::.:::... :: ::::::::::.::::.:.... . . .::: :: ..: ::. : NP_001 NPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAA 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB5 VNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLDDLLQL . . :: . .:.:. :. : . : :.:::::....: :.:..:.::. : .: NP_001 REALLSSAVD-HGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNL 100 110 120 130 140 200 210 220 230 240 250 pF1KB5 KMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELEL-KAEKD . : : : ::.: :: : : . : .. :::. .: :: . :. .. : . NP_001 EAIHIIKKLGGSLADSYLDEGFLLDKKIGVN----QPKRIENAKILIANTGMDTDKIKIF 150 160 170 180 190 200 260 270 280 290 300 310 pF1KB5 NAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCA ....:: .. : :: . . .:.:.: . : . ... : . : :. .. NP_001 GSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAI 210 220 230 240 250 260 320 330 340 350 360 370 pF1KB5 GRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNFFTGCPKAKTCT .. ..: .. :: : .. . :: :...::..:: .. :.: ...:: NP_001 EHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACT 270 280 290 300 310 320 380 390 400 410 420 430 pF1KB5 FILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQ ..:::...:...:.:::::::. .. ...:.. .: ::: :: ... . . . :::. NP_001 IVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKE 330 340 350 360 370 380 440 450 460 470 480 490 pF1KB5 QLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAF . . .:::::...: . ::::.:..... .::: :..:.: :.:. . :.: NP_001 AVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILG 390 400 410 420 430 440 500 510 520 530 540 pF1KB5 VWEPAMVRINALTAASEAACLIVSVDETIKN-PRSTVDAPTAAGRGRGRGRPH . : .:. ..: .:.::: .:. ::. :: ::. : NP_001 ITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC 450 460 470 480 543 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 16:19:25 2016 done: Thu Nov 3 16:19:26 2016 Total Scan time: 9.500 Total Display time: 0.120 Function used was FASTA [36.3.4 Apr, 2011]