FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5208, 369 aa 1>>>pF1KB5208 369 - 369 aa - 369 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4857+/-0.000505; mu= 15.1363+/- 0.031 mean_var=97.4848+/-24.558, 0's: 0 Z-trim(108.6): 802 B-trim: 1464 in 2/47 Lambda= 0.129899 statistics sampled from 15855 (16753) to 15855 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.54), E-opt: 0.2 (0.196), width: 16 Scan time: 7.410 The best scores are: opt bits E(85289) NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 2430 466.7 3.7e-131 NP_001166031 (OMIM: 182455) somatostatin receptor ( 364) 1289 252.9 8.6e-67 NP_001044 (OMIM: 182455) somatostatin receptor typ ( 364) 1289 252.9 8.6e-67 XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 1192 234.8 2.8e-61 XP_011528651 (OMIM: 182453) PREDICTED: somatostati ( 418) 1192 234.8 2.8e-61 NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 1192 234.8 2.8e-61 XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 1192 234.8 2.8e-61 XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 1192 234.8 2.8e-61 NP_001042 (OMIM: 182453) somatostatin receptor typ ( 418) 1192 234.8 2.8e-61 XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 1192 234.8 2.8e-61 NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 1143 225.5 1.6e-58 NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 1110 219.4 1.1e-56 NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 856 171.8 2.5e-42 NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 856 171.9 2.9e-42 NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 856 171.9 2.9e-42 NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 848 170.3 7.2e-42 NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 847 170.1 8e-42 NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 847 170.1 8.2e-42 NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 846 169.9 8.8e-42 NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 846 169.9 8.9e-42 NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 846 169.9 9e-42 NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 846 169.9 9.1e-42 NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 846 169.9 9.2e-42 NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446) 846 169.9 9.7e-42 NP_005277 (OMIM: 600731) neuropeptides B/W recepto ( 333) 832 167.2 4.9e-41 NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 829 166.7 7.9e-41 NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 829 166.7 8.3e-41 NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 806 162.4 1.5e-39 NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 795 160.3 6.4e-39 NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 795 160.3 6.4e-39 NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 795 160.3 6.4e-39 XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 795 160.3 6.4e-39 XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 795 160.3 6.6e-39 XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 795 160.3 6.6e-39 XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 795 160.3 6.6e-39 NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 795 160.3 6.8e-39 NP_005276 (OMIM: 600730) neuropeptides B/W recepto ( 328) 772 155.9 1.2e-37 NP_001138753 (OMIM: 600018) mu-type opioid recepto ( 319) 764 154.4 3.2e-37 XP_016883344 (OMIM: 602548) PREDICTED: nociceptin ( 365) 745 150.9 4.2e-36 NP_001305783 (OMIM: 602548) nociceptin receptor is ( 365) 745 150.9 4.2e-36 NP_001272455 (OMIM: 600018) mu-type opioid recepto ( 300) 743 150.5 4.7e-36 NP_001138752 (OMIM: 600018) mu-type opioid recepto ( 300) 743 150.5 4.7e-36 XP_016866395 (OMIM: 600018) PREDICTED: mu-type opi ( 300) 743 150.5 4.7e-36 NP_001138759 (OMIM: 600018) mu-type opioid recepto ( 300) 743 150.5 4.7e-36 NP_001272456 (OMIM: 600018) mu-type opioid recepto ( 292) 733 148.6 1.7e-35 NP_001272457 (OMIM: 600018) mu-type opioid recepto ( 314) 733 148.6 1.8e-35 XP_011534158 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 733 148.7 1.9e-35 XP_011534153 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 733 148.7 1.9e-35 XP_011534164 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 733 148.7 1.9e-35 XP_016866393 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 733 148.7 1.9e-35 >>NP_001041 (OMIM: 182452) somatostatin receptor type 2 (369 aa) initn: 2430 init1: 2430 opt: 2430 Z-score: 2475.7 bits: 466.7 E(85289): 3.7e-131 Smith-Waterman score: 2430; 100.0% identity (100.0% similar) in 369 aa overlap (1-369:1-369) 10 20 30 40 50 60 pF1KB5 MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 NTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 AGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 RVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 TYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTL 310 320 330 340 350 360 pF1KB5 LNGDLQTSI ::::::::: NP_001 LNGDLQTSI >>NP_001166031 (OMIM: 182455) somatostatin receptor type (364 aa) initn: 1278 init1: 654 opt: 1289 Z-score: 1320.1 bits: 252.9 E(85289): 8.6e-67 Smith-Waterman score: 1289; 55.7% identity (79.8% similar) in 336 aa overlap (36-368:32-362) 10 20 30 40 50 60 pF1KB5 EPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLT-FIYFVVCIIGLCGNTLV : . . :::. .:..:: :: ::::: NP_001 EPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 IYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGI :::.::.:::::.:::::::::.:: :.:::::::: : : :::: ..::.:::.::. NP_001 IYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLR :::::.:::::::.:::::::::..::.:::::.::. . :.: .:: . ::....: . NP_001 NQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADV- 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGS : : ..:. .:: : : . ::::: .:::..:: .::::::.:..::...:.::: NP_001 --QEG-GTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGC 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 SKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYAN .:. ::.:::::: .:: :: :::::. :. ....:. :: :.. :::.:.::: NP_001 VRRR-SERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYAN 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 SCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNE--TTETQRTLLN :::::.::.::::::..:::.:::: : ::. :.. .. . :. : .. : ..:. : NP_001 SCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAAN 300 310 320 330 340 350 pF1KB5 GDLQTSI : .::: NP_001 GLMQTSKL 360 >>NP_001044 (OMIM: 182455) somatostatin receptor type 5 (364 aa) initn: 1278 init1: 654 opt: 1289 Z-score: 1320.1 bits: 252.9 E(85289): 8.6e-67 Smith-Waterman score: 1289; 55.7% identity (79.8% similar) in 336 aa overlap (36-368:32-362) 10 20 30 40 50 60 pF1KB5 EPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLT-FIYFVVCIIGLCGNTLV : . . :::. .:..:: :: ::::: NP_001 EPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 IYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGI :::.::.:::::.:::::::::.:: :.:::::::: : : :::: ..::.:::.::. NP_001 IYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLR :::::.:::::::.:::::::::..::.:::::.::. . :.: .:: . ::....: . NP_001 NQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADV- 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGS : : ..:. .:: : : . ::::: .:::..:: .::::::.:..::...:.::: NP_001 --QEG-GTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGC 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 SKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYAN .:. ::.:::::: .:: :: :::::. :. ....:. :: :.. :::.:.::: NP_001 VRRR-SERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYAN 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 SCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNE--TTETQRTLLN :::::.::.::::::..:::.:::: : ::. :.. .. . :. : .. : ..:. : NP_001 SCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAAN 300 310 320 330 340 350 pF1KB5 GDLQTSI : .::: NP_001 GLMQTSKL 360 >>XP_005261778 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 914 init1: 914 opt: 1192 Z-score: 1221.1 bits: 234.8 E(85289): 2.8e-61 Smith-Waterman score: 1192; 53.2% identity (78.8% similar) in 325 aa overlap (6-327:14-328) 10 20 30 40 50 pF1KB5 MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFV :: :.: .: : : . . ::.. : : .:.... ..:.: XP_005 MDMLHPSSVSTTSEPENASSAW---PPDATLGNVSAGPS----PAGLAVSGVLIPLVYLV 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 VCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGK ::..:: ::.:::::.::.. ..::.::::::.::::::::::::: : :: .::::. XP_005 VCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 AICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLL .::.::.:::::::::::::::::.::::::::: .::.:: .:. .. ::: .: . XP_005 LMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 VILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFII :.::.....:. : :.: ..:: ..:: .:::::: :::. :: .::::::.:. XP_005 VVLPVVVFSGV---PRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIV 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 IKVKSSGIRV---GSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPA .::.:.: :: . ..:..::..::::: :::.:..::.:::..:. .: . :: XP_005 VKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPA 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 LKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSR . :.. .::.: :::::::::::.::: ::..:. :: XP_005 FFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEE 300 310 320 330 340 350 350 360 pF1KB5 LNETTETQRTLLNGDLQTSI XP_005 EDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKS 360 370 380 390 400 410 >>XP_011528651 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 914 init1: 914 opt: 1192 Z-score: 1221.1 bits: 234.8 E(85289): 2.8e-61 Smith-Waterman score: 1192; 53.2% identity (78.8% similar) in 325 aa overlap (6-327:14-328) 10 20 30 40 50 pF1KB5 MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFV :: :.: .: : : . . ::.. : : .:.... ..:.: XP_011 MDMLHPSSVSTTSEPENASSAW---PPDATLGNVSAGPS----PAGLAVSGVLIPLVYLV 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 VCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGK ::..:: ::.:::::.::.. ..::.::::::.::::::::::::: : :: .::::. XP_011 VCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 AICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLL .::.::.:::::::::::::::::.::::::::: .::.:: .:. .. ::: .: . XP_011 LMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 VILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFII :.::.....:. : :.: ..:: ..:: .:::::: :::. :: .::::::.:. XP_011 VVLPVVVFSGV---PRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIV 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 IKVKSSGIRV---GSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPA .::.:.: :: . ..:..::..::::: :::.:..::.:::..:. .: . :: XP_011 VKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPA 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 LKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSR . :.. .::.: :::::::::::.::: ::..:. :: XP_011 FFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEE 300 310 320 330 340 350 350 360 pF1KB5 LNETTETQRTLLNGDLQTSI XP_011 EDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKS 360 370 380 390 400 410 >>NP_001265616 (OMIM: 182453) somatostatin receptor type (418 aa) initn: 914 init1: 914 opt: 1192 Z-score: 1221.1 bits: 234.8 E(85289): 2.8e-61 Smith-Waterman score: 1192; 53.2% identity (78.8% similar) in 325 aa overlap (6-327:14-328) 10 20 30 40 50 pF1KB5 MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFV :: :.: .: : : . . ::.. : : .:.... ..:.: NP_001 MDMLHPSSVSTTSEPENASSAW---PPDATLGNVSAGPS----PAGLAVSGVLIPLVYLV 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 VCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGK ::..:: ::.:::::.::.. ..::.::::::.::::::::::::: : :: .::::. NP_001 VCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 AICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLL .::.::.:::::::::::::::::.::::::::: .::.:: .:. .. ::: .: . NP_001 LMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 VILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFII :.::.....:. : :.: ..:: ..:: .:::::: :::. :: .::::::.:. NP_001 VVLPVVVFSGV---PRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIV 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 IKVKSSGIRV---GSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPA .::.:.: :: . ..:..::..::::: :::.:..::.:::..:. .: . :: NP_001 VKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPA 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 LKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSR . :.. .::.: :::::::::::.::: ::..:. :: NP_001 FFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEE 300 310 320 330 340 350 350 360 pF1KB5 LNETTETQRTLLNGDLQTSI NP_001 EDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKS 360 370 380 390 400 410 >>XP_006724374 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 914 init1: 914 opt: 1192 Z-score: 1221.1 bits: 234.8 E(85289): 2.8e-61 Smith-Waterman score: 1192; 53.2% identity (78.8% similar) in 325 aa overlap (6-327:14-328) 10 20 30 40 50 pF1KB5 MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFV :: :.: .: : : . . ::.. : : .:.... ..:.: XP_006 MDMLHPSSVSTTSEPENASSAW---PPDATLGNVSAGPS----PAGLAVSGVLIPLVYLV 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 VCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGK ::..:: ::.:::::.::.. ..::.::::::.::::::::::::: : :: .::::. XP_006 VCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 AICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLL .::.::.:::::::::::::::::.::::::::: .::.:: .:. .. ::: .: . XP_006 LMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 VILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFII :.::.....:. : :.: ..:: ..:: .:::::: :::. :: .::::::.:. XP_006 VVLPVVVFSGV---PRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIV 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 IKVKSSGIRV---GSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPA .::.:.: :: . ..:..::..::::: :::.:..::.:::..:. .: . :: XP_006 VKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPA 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 LKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSR . :.. .::.: :::::::::::.::: ::..:. :: XP_006 FFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEE 300 310 320 330 340 350 350 360 pF1KB5 LNETTETQRTLLNGDLQTSI XP_006 EDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKS 360 370 380 390 400 410 >>XP_016884413 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 914 init1: 914 opt: 1192 Z-score: 1221.1 bits: 234.8 E(85289): 2.8e-61 Smith-Waterman score: 1192; 53.2% identity (78.8% similar) in 325 aa overlap (6-327:14-328) 10 20 30 40 50 pF1KB5 MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFV :: :.: .: : : . . ::.. : : .:.... ..:.: XP_016 MDMLHPSSVSTTSEPENASSAW---PPDATLGNVSAGPS----PAGLAVSGVLIPLVYLV 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 VCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGK ::..:: ::.:::::.::.. ..::.::::::.::::::::::::: : :: .::::. XP_016 VCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 AICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLL .::.::.:::::::::::::::::.::::::::: .::.:: .:. .. ::: .: . XP_016 LMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 VILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFII :.::.....:. : :.: ..:: ..:: .:::::: :::. :: .::::::.:. XP_016 VVLPVVVFSGV---PRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIV 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 IKVKSSGIRV---GSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPA .::.:.: :: . ..:..::..::::: :::.:..::.:::..:. .: . :: XP_016 VKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPA 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 LKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSR . :.. .::.: :::::::::::.::: ::..:. :: XP_016 FFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEE 300 310 320 330 340 350 350 360 pF1KB5 LNETTETQRTLLNGDLQTSI XP_016 EDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKS 360 370 380 390 400 410 >>NP_001042 (OMIM: 182453) somatostatin receptor type 3 (418 aa) initn: 914 init1: 914 opt: 1192 Z-score: 1221.1 bits: 234.8 E(85289): 2.8e-61 Smith-Waterman score: 1192; 53.2% identity (78.8% similar) in 325 aa overlap (6-327:14-328) 10 20 30 40 50 pF1KB5 MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFV :: :.: .: : : . . ::.. : : .:.... ..:.: NP_001 MDMLHPSSVSTTSEPENASSAW---PPDATLGNVSAGPS----PAGLAVSGVLIPLVYLV 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 VCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGK ::..:: ::.:::::.::.. ..::.::::::.::::::::::::: : :: .::::. NP_001 VCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 AICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLL .::.::.:::::::::::::::::.::::::::: .::.:: .:. .. ::: .: . NP_001 LMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 VILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFII :.::.....:. : :.: ..:: ..:: .:::::: :::. :: .::::::.:. NP_001 VVLPVVVFSGV---PRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIV 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 IKVKSSGIRV---GSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPA .::.:.: :: . ..:..::..::::: :::.:..::.:::..:. .: . :: NP_001 VKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPA 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 LKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSR . :.. .::.: :::::::::::.::: ::..:. :: NP_001 FFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEE 300 310 320 330 340 350 350 360 pF1KB5 LNETTETQRTLLNGDLQTSI NP_001 EDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKS 360 370 380 390 400 410 >>XP_016884412 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 914 init1: 914 opt: 1192 Z-score: 1221.1 bits: 234.8 E(85289): 2.8e-61 Smith-Waterman score: 1192; 53.2% identity (78.8% similar) in 325 aa overlap (6-327:14-328) 10 20 30 40 50 pF1KB5 MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFV :: :.: .: : : . . ::.. : : .:.... ..:.: XP_016 MDMLHPSSVSTTSEPENASSAW---PPDATLGNVSAGPS----PAGLAVSGVLIPLVYLV 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 VCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGK ::..:: ::.:::::.::.. ..::.::::::.::::::::::::: : :: .::::. XP_016 VCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 AICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLL .::.::.:::::::::::::::::.::::::::: .::.:: .:. .. ::: .: . XP_016 LMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 VILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFII :.::.....:. : :.: ..:: ..:: .:::::: :::. :: .::::::.:. XP_016 VVLPVVVFSGV---PRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIV 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 IKVKSSGIRV---GSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPA .::.:.: :: . ..:..::..::::: :::.:..::.:::..:. .: . :: XP_016 VKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPA 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 LKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSR . :.. .::.: :::::::::::.::: ::..:. :: XP_016 FFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEE 300 310 320 330 340 350 350 360 pF1KB5 LNETTETQRTLLNGDLQTSI XP_016 EDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKS 360 370 380 390 400 410 369 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 16:20:01 2016 done: Thu Nov 3 16:20:02 2016 Total Scan time: 7.410 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]