FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5212, 394 aa 1>>>pF1KB5212 394 - 394 aa - 394 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6559+/-0.000871; mu= 15.4464+/- 0.053 mean_var=72.4473+/-14.881, 0's: 0 Z-trim(106.7): 40 B-trim: 300 in 1/49 Lambda= 0.150683 statistics sampled from 9083 (9117) to 9083 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.655), E-opt: 0.2 (0.28), width: 16 Scan time: 2.800 The best scores are: opt bits E(32554) CCDS13472.1 GNAS gene_id:2778|Hs108|chr20 ( 394) 2642 583.5 1.1e-166 CCDS46623.1 GNAS gene_id:2778|Hs108|chr20 ( 395) 2630 580.9 6.7e-166 CCDS46622.1 GNAS gene_id:2778|Hs108|chr20 (1037) 2457 543.5 3.2e-154 CCDS46624.1 GNAS gene_id:2778|Hs108|chr20 ( 380) 2096 464.8 5.7e-131 CCDS42892.1 GNAS gene_id:2778|Hs108|chr20 ( 379) 2084 462.2 3.5e-130 CCDS11851.1 GNAL gene_id:2774|Hs108|chr18 ( 458) 1777 395.5 5e-110 CCDS11852.1 GNAL gene_id:2774|Hs108|chr18 ( 381) 1749 389.4 2.9e-108 CCDS58614.1 GNAL gene_id:2774|Hs108|chr18 ( 174) 1078 243.4 1.2e-64 CCDS10757.1 GNAO1 gene_id:2775|Hs108|chr16 ( 354) 660 152.7 5e-37 CCDS12104.1 GNA15 gene_id:2769|Hs108|chr19 ( 374) 660 152.7 5.3e-37 CCDS10756.1 GNAO1 gene_id:2775|Hs108|chr16 ( 354) 659 152.4 5.8e-37 CCDS803.1 GNAT2 gene_id:2780|Hs108|chr1 ( 354) 653 151.1 1.4e-36 CCDS2813.1 GNAI2 gene_id:2771|Hs108|chr3 ( 355) 651 150.7 2e-36 CCDS63644.1 GNAI2 gene_id:2771|Hs108|chr3 ( 303) 649 150.2 2.3e-36 CCDS54587.1 GNAI2 gene_id:2771|Hs108|chr3 ( 318) 649 150.2 2.4e-36 CCDS63642.1 GNAI2 gene_id:2771|Hs108|chr3 ( 339) 649 150.3 2.5e-36 CCDS47625.1 GNAT3 gene_id:346562|Hs108|chr7 ( 354) 648 150.1 3.1e-36 CCDS802.1 GNAI3 gene_id:2773|Hs108|chr1 ( 354) 645 149.4 4.8e-36 CCDS59061.1 GNAI1 gene_id:2770|Hs108|chr7 ( 302) 637 147.6 1.4e-35 CCDS5595.1 GNAI1 gene_id:2770|Hs108|chr7 ( 354) 637 147.7 1.6e-35 CCDS2812.1 GNAT1 gene_id:2779|Hs108|chr3 ( 350) 626 145.3 8.4e-35 CCDS6658.1 GNAQ gene_id:2776|Hs108|chr9 ( 359) 620 144.0 2.1e-34 CCDS13804.1 GNAZ gene_id:2781|Hs108|chr22 ( 355) 607 141.1 1.5e-33 CCDS12103.1 GNA11 gene_id:2767|Hs108|chr19 ( 359) 607 141.1 1.5e-33 CCDS6657.1 GNA14 gene_id:9630|Hs108|chr9 ( 355) 594 138.3 1.1e-32 CCDS82633.1 GNAS gene_id:2778|Hs108|chr20 ( 87) 561 130.8 4.6e-31 CCDS62302.1 GNA13 gene_id:10672|Hs108|chr17 ( 282) 566 132.2 5.9e-31 CCDS5335.1 GNA12 gene_id:2768|Hs108|chr7 ( 381) 567 132.5 6.5e-31 CCDS11661.1 GNA13 gene_id:10672|Hs108|chr17 ( 377) 566 132.2 7.5e-31 CCDS64584.1 GNA12 gene_id:2768|Hs108|chr7 ( 322) 560 130.9 1.6e-30 CCDS64583.1 GNA12 gene_id:2768|Hs108|chr7 ( 305) 479 113.3 3.1e-25 >>CCDS13472.1 GNAS gene_id:2778|Hs108|chr20 (394 aa) initn: 2642 init1: 2642 opt: 2642 Z-score: 3106.1 bits: 583.5 E(32554): 1.1e-166 Smith-Waterman score: 2642; 100.0% identity (100.0% similar) in 394 aa overlap (1-394:1-394) 10 20 30 40 50 60 pF1KB5 MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 RILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 RILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 NPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 KIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 KIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFND 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 VLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCY 310 320 330 340 350 360 370 380 390 pF1KB5 PHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL :::::::::::::::::::::::::::::::::: CCDS13 PHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL 370 380 390 >>CCDS46623.1 GNAS gene_id:2778|Hs108|chr20 (395 aa) initn: 2094 init1: 2094 opt: 2630 Z-score: 3091.9 bits: 580.9 E(32554): 6.7e-166 Smith-Waterman score: 2630; 99.7% identity (99.7% similar) in 395 aa overlap (1-394:1-395) 10 20 30 40 50 60 pF1KB5 MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQM 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 RILHVNGFNGEGGEEDPQAARSNSDG-EKATKVQDIKNNLKEAIETIVAAMSNLVPPVEL :::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: CCDS46 RILHVNGFNGEGGEEDPQAARSNSDGSEKATKVQDIKNNLKEAIETIVAAMSNLVPPVEL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 ANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 DKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 DKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFN 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB5 DVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 DVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB5 KVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 KVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYC 310 320 330 340 350 360 360 370 380 390 pF1KB5 YPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL ::::::::::::::::::::::::::::::::::: CCDS46 YPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL 370 380 390 >>CCDS46622.1 GNAS gene_id:2778|Hs108|chr20 (1037 aa) initn: 2457 init1: 2457 opt: 2457 Z-score: 2882.3 bits: 543.5 E(32554): 3.2e-154 Smith-Waterman score: 2457; 95.1% identity (98.2% similar) in 384 aa overlap (11-394:654-1037) 10 20 30 40 pF1KB5 MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRAT ..: ...:... .: :.:::: .:. : : CCDS46 ESPQPKASRSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCT 630 640 650 660 670 680 50 60 70 80 90 100 pF1KB5 HRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 HRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLK 690 700 710 720 730 740 110 120 130 140 150 160 pF1KB5 EAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 EAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVR 750 760 770 780 790 800 170 180 190 200 210 220 pF1KB5 ACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFH 810 820 830 840 850 860 230 240 250 260 270 280 pF1KB5 MFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNR 870 880 890 900 910 920 290 300 310 320 330 340 pF1KB5 WLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 WLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYF 930 940 950 960 970 980 350 360 370 380 390 pF1KB5 IRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 IRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL 990 1000 1010 1020 1030 >>CCDS46624.1 GNAS gene_id:2778|Hs108|chr20 (380 aa) initn: 2096 init1: 2096 opt: 2096 Z-score: 2464.8 bits: 464.8 E(32554): 5.7e-131 Smith-Waterman score: 2503; 96.2% identity (96.4% similar) in 394 aa overlap (1-394:1-380) 10 20 30 40 50 60 pF1KB5 MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 RILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELA :::::::::: :.:::::::::::::::::::::::::::::::::: CCDS46 RILHVNGFNG--------------DSEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELA 70 80 90 100 130 140 150 160 170 180 pF1KB5 NPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 NPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLD 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB5 KIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 KIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFND 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB5 VTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEK 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB5 VLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCY 290 300 310 320 330 340 370 380 390 pF1KB5 PHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL :::::::::::::::::::::::::::::::::: CCDS46 PHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL 350 360 370 380 >>CCDS42892.1 GNAS gene_id:2778|Hs108|chr20 (379 aa) initn: 2081 init1: 2081 opt: 2084 Z-score: 2450.7 bits: 462.2 E(32554): 3.5e-130 Smith-Waterman score: 2495; 95.9% identity (96.2% similar) in 394 aa overlap (1-394:1-379) 10 20 30 40 50 60 pF1KB5 MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 RILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELA ::::::::::. :::::::::::::::::::::::::::::::::: CCDS42 RILHVNGFNGD---------------EKATKVQDIKNNLKEAIETIVAAMSNLVPPVELA 70 80 90 100 130 140 150 160 170 180 pF1KB5 NPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 NPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLD 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB5 KIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 KIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFND 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB5 VTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEK 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB5 VLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCY 290 300 310 320 330 340 370 380 390 pF1KB5 PHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL :::::::::::::::::::::::::::::::::: CCDS42 PHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL 350 360 370 >>CCDS11851.1 GNAL gene_id:2774|Hs108|chr18 (458 aa) initn: 1786 init1: 1749 opt: 1777 Z-score: 2088.8 bits: 395.5 E(32554): 5e-110 Smith-Waterman score: 1939; 73.6% identity (88.5% similar) in 383 aa overlap (12-394:91-458) 10 20 30 40 pF1KB5 MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATH .:. : :.... :...:. .:. . :: CCDS11 PACARPKADKPKEKRQRTEQLSAEEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTH 70 80 90 100 110 120 50 60 70 80 90 100 pF1KB5 RLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKE :::::::::::::::::::::::::::: : :: :. ::..:.:. CCDS11 RLLLLGAGESGKSTIVKQMRILHVNGFNPE---------------EKKQKILDIRKNVKD 130 140 150 160 110 120 130 140 150 160 pF1KB5 AIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRA :: :::.:::...::: ::::::::: ::: :. . ::.. ::..:.: ::.::::.: CCDS11 AIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKA 170 180 190 200 210 220 170 180 190 200 210 220 pF1KB5 CYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHM :.::::::::::::::::..:: .. .::.:.:::::::::::::::::.:::::::::: CCDS11 CFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHM 230 240 250 260 270 280 230 240 250 260 270 280 pF1KB5 FDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRW ::::::::::::::::::::::::.:.: :::::::::::.::::.:.:.::.::::::: CCDS11 FDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRW 290 300 310 320 330 340 290 300 310 320 330 340 pF1KB5 LRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFI :::::.::::::::.::::::::::::::::::.: ::.::::::. ::::.:::::.:: CCDS11 LRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFI 350 360 370 380 390 400 350 360 370 380 390 pF1KB5 RDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL :: :::::::.:::.::::::::::::::::::::::::::::::::.::::: CCDS11 RDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL 410 420 430 440 450 >>CCDS11852.1 GNAL gene_id:2774|Hs108|chr18 (381 aa) initn: 1782 init1: 1749 opt: 1749 Z-score: 2057.1 bits: 389.4 E(32554): 2.9e-108 Smith-Waterman score: 2070; 77.0% identity (89.6% similar) in 396 aa overlap (1-394:1-381) 10 20 30 40 50 pF1KB5 MGCLG-NSKT-EDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVK ::::: :::: ::: .:: .:::::::::::::.. .:.:::::::::::::::::::: CCDS11 MGCLGGNSKTTEDQGVDEKERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 QMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVE ::::::::::: : :: :. ::..:.:.:: :::.:::...::: CCDS11 QMRILHVNGFNPE---------------EKKQKILDIRKNVKDAIVTIVSAMSTIIPPVP 70 80 90 100 120 130 140 150 160 170 pF1KB5 LANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYF ::::::::: ::: :. . ::.. ::..:.: ::.::::.::.::::::::::::::: CCDS11 LANPENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYF 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB5 LDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCF :..:: .. .::.:.:::::::::::::::::.::::::::::::::::::::::::::: CCDS11 LERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCF 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB5 NDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLA :::::::.:.: :::::::::::.::::.:.:.::.::::::::::::.::::::::.:: CCDS11 NDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLA 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB5 EKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHY ::::::::::::::::.: ::.::::::. ::::.:::::.:::: :::::::.:::.:: CCDS11 EKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHY 290 300 310 320 330 340 360 370 380 390 pF1KB5 CYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL ::::::::::::::::::::::::::::::.::::: CCDS11 CYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL 350 360 370 380 >>CCDS58614.1 GNAL gene_id:2774|Hs108|chr18 (174 aa) initn: 1078 init1: 1078 opt: 1078 Z-score: 1274.0 bits: 243.4 E(32554): 1.2e-64 Smith-Waterman score: 1078; 87.9% identity (97.7% similar) in 174 aa overlap (221-394:1-174) 200 210 220 230 240 250 pF1KB5 VPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVAS :::::::::::::::::::::::::.:.: CCDS58 MFDVGGQRDERRKWIQCFNDVTAIIYVAAC 10 20 30 260 270 280 290 300 310 pF1KB5 SSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIED :::::::::::.::::.:.:.::.::::::::::::.::::::::.:::::::::::::: CCDS58 SSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIED 40 50 60 70 80 90 320 330 340 350 360 370 pF1KB5 YFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTE ::::.: ::.::::::. ::::.:::::.:::: :::::::.:::.:::::::::::::: CCDS58 YFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTE 100 110 120 130 140 150 380 390 pF1KB5 NIRRVFNDCRDIIQRMHLRQYELL ::::::::::::::::::.::::: CCDS58 NIRRVFNDCRDIIQRMHLKQYELL 160 170 >>CCDS10757.1 GNAO1 gene_id:2775|Hs108|chr16 (354 aa) initn: 883 init1: 608 opt: 660 Z-score: 778.2 bits: 152.7 E(32554): 5e-37 Smith-Waterman score: 869; 41.4% identity (65.2% similar) in 391 aa overlap (1-389:1-349) 10 20 30 40 50 60 pF1KB5 MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQM ::: .. ::.: : .: :::.:..: .:::::::::::::::::: CCDS10 MGCTLSA-------EERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQM 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 RILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELA .:.: .::.:: .. .. ::. .: .. .:: ::..: .: . CCDS10 KIIHEDGFSGEDVKQYKPVVYSNT-------IQ--------SLAAIVRAMDTL--GIEYG 60 70 80 90 130 140 150 160 170 pF1KB5 NPENQFRVDYILSVMN-VPDFD-FPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYF . : . . .. .:.. . : . : :. :: : :.. :..:: :::: : :.:. CCDS10 DKERKADAKMVCDVVSRMEDTEPFSAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYY 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB5 LDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCF ::..: : ::: :..::.:: :: :.:: ::.: ...:..:::::::.::.:::.:: CCDS10 LDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCF 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB5 NDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLA .::::::: :: :.:..:..::. :::..:.:.:: :: ::.:. :.::::::.:.. CCDS10 EDVTAIIFCVALSGYDQVLHEDETTNRMHESLKLFDSICNNKWFTDTSIILFLNKKDIFE 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB5 EKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHY ::. :: . ::: :: : :.: .:. .. . . .... CCDS10 EKI--KKSPLTICFPE---YTGPSA----------FTEAVAYIQAQY---ESKNKSAHKE 280 290 300 310 360 370 380 390 pF1KB5 CYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL : : :::.::.::. ::. :.: .:: CCDS10 IYTHVTCATDTNNIQFVFDAVTDVIIAKNLRGCGLY 320 330 340 350 >>CCDS12104.1 GNA15 gene_id:2769|Hs108|chr19 (374 aa) initn: 843 init1: 543 opt: 660 Z-score: 777.8 bits: 152.7 E(32554): 5.3e-37 Smith-Waterman score: 824; 37.2% identity (62.8% similar) in 401 aa overlap (3-394:9-374) 10 20 30 40 50 pF1KB5 MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKS : :::.. ....: :. . .: ..: :. .::::: :::::: CCDS12 MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQD----RGELKLLLLGPGESGKS 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 TIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLV :..:::::.: :.. ::. . : . :.: ... :: :: : CCDS12 TFIKQMRIIHGAGYS----EEERK-------GFRPLVYQNIFVSMRAMIE----AMERLQ 60 70 80 90 100 120 130 140 150 160 170 pF1KB5 PPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDC : .. ::.. ... ..: : .. . ::.: :.:::::: :..:.: CCDS12 IP--FSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDS 110 120 130 140 150 180 190 200 210 220 230 pF1KB5 AQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKW : :.:.... : . :::. ::.:: :. :.:: : :.:.:.:... :::::..::.:: CCDS12 AVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKW 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB5 IQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQ :.::..: :.:.... : :.. ..:.:: ::..:.: :: .: . :... :::::::: CCDS12 IHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKT 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB5 DLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGD :.: ::. :.. ::: : : .: .. :: :: : . :. :. : CCDS12 DILEEKI--PTSHLATYFPSFQG----------PKQDAEA--AKRFILDMYTRMYTGCVD 280 290 300 310 320 360 370 380 390 pF1KB5 G---------RHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL : . . :.:::.::.:::.::.: :: . .: . .:: CCDS12 GPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL 330 340 350 360 370 394 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 16:20:43 2016 done: Thu Nov 3 16:20:44 2016 Total Scan time: 2.800 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]