FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5213, 145 aa
1>>>pF1KB5213 145 - 145 aa - 145 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.5938+/-0.000269; mu= 15.4160+/- 0.017
mean_var=59.4097+/-11.906, 0's: 0 Z-trim(119.7): 98 B-trim: 240 in 2/51
Lambda= 0.166397
statistics sampled from 33967 (34078) to 33967 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.785), E-opt: 0.2 (0.4), width: 16
Scan time: 4.440
The best scores are: opt bits E(85289)
NP_003341 (OMIM: 603001) ubiquitin-conjugating enz ( 145) 977 241.9 2.8e-64
XP_011515885 (OMIM: 603001) PREDICTED: ubiquitin-c ( 173) 950 235.4 2.8e-62
XP_016869297 (OMIM: 603001) PREDICTED: ubiquitin-c ( 142) 942 233.5 9.3e-62
NP_001027459 (OMIM: 602995) ubiquitin-conjugating ( 147) 886 220.0 1.1e-57
NP_001244322 (OMIM: 602995) ubiquitin-conjugating ( 170) 881 218.9 2.7e-57
NP_954595 (OMIM: 602995) ubiquitin-conjugating enz ( 170) 881 218.9 2.7e-57
NP_068823 (OMIM: 602995) ubiquitin-conjugating enz ( 170) 881 218.9 2.7e-57
NP_001244324 (OMIM: 602995) ubiquitin-conjugating ( 144) 877 217.9 4.7e-57
XP_005251357 (OMIM: 603001) PREDICTED: ubiquitin-c ( 105) 711 177.9 3.6e-45
NP_001244327 (OMIM: 602995) ubiquitin-conjugating ( 105) 642 161.3 3.5e-40
NP_001244328 (OMIM: 602995) ubiquitin-conjugating ( 105) 642 161.3 3.5e-40
NP_001244326 (OMIM: 602995) ubiquitin-conjugating ( 105) 642 161.3 3.5e-40
NP_001269508 (OMIM: 602995) ubiquitin-conjugating ( 105) 642 161.3 3.5e-40
NP_001269505 (OMIM: 602995) ubiquitin-conjugating ( 105) 642 161.3 3.5e-40
NP_071887 (OMIM: 602995) ubiquitin-conjugating enz ( 103) 540 136.8 8.2e-33
NP_001244323 (OMIM: 602995) ubiquitin-conjugating ( 103) 540 136.8 8.2e-33
NP_001269504 (OMIM: 602995) ubiquitin-conjugating ( 91) 533 135.1 2.4e-32
NP_001269506 (OMIM: 602995) ubiquitin-conjugating ( 91) 533 135.1 2.4e-32
NP_001269507 (OMIM: 602995) ubiquitin-conjugating ( 91) 533 135.1 2.4e-32
NP_001269509 (OMIM: 602995) ubiquitin-conjugating ( 64) 353 91.8 1.8e-19
NP_001244325 (OMIM: 602995) ubiquitin-conjugating ( 105) 355 92.4 1.9e-19
NP_001104582 (OMIM: 602846) ubiquitin-conjugating ( 157) 191 53.2 1.9e-07
NP_005330 (OMIM: 602846) ubiquitin-conjugating enz ( 200) 191 53.3 2.2e-07
NP_054895 (OMIM: 610538,616435) ubiquitin-conjugat ( 197) 173 49.0 4.4e-06
NP_003327 (OMIM: 300860,312180) ubiquitin-conjugat ( 152) 166 47.2 1.2e-05
NP_003328 (OMIM: 179095) ubiquitin-conjugating enz ( 152) 162 46.2 2.3e-05
NP_003333 (OMIM: 601569) ubiquitin-conjugating enz ( 170) 158 45.3 4.8e-05
NP_003329 (OMIM: 602961) ubiquitin-conjugating enz ( 147) 157 45.0 5.1e-05
NP_001269090 (OMIM: 300860,312180) ubiquitin-conju ( 119) 155 44.5 6e-05
NP_001297255 (OMIM: 610538,616435) ubiquitin-conju ( 167) 155 44.6 7.8e-05
NP_003332 (OMIM: 602916) ubiquitin-conjugating enz ( 193) 155 44.6 8.7e-05
NP_001189405 (OMIM: 602916) ubiquitin-conjugating ( 160) 153 44.1 0.00011
XP_005265488 (OMIM: 602916) PREDICTED: ubiquitin-c ( 167) 153 44.1 0.00011
NP_872607 (OMIM: 602916) ubiquitin-conjugating enz ( 176) 152 43.9 0.00013
XP_005265490 (OMIM: 602163) PREDICTED: ubiquitin-c ( 189) 152 43.9 0.00014
NP_689866 (OMIM: 602163) ubiquitin-conjugating enz ( 201) 152 43.9 0.00015
XP_005265489 (OMIM: 602163) PREDICTED: ubiquitin-c ( 201) 152 43.9 0.00015
NP_004214 (OMIM: 603890) ubiquitin/ISG15-conjugati ( 153) 148 42.9 0.00023
XP_011534190 (OMIM: 616175) PREDICTED: ubiquitin-c ( 235) 149 43.3 0.00028
XP_011534189 (OMIM: 616175) PREDICTED: ubiquitin-c ( 278) 149 43.3 0.00031
NP_057105 (OMIM: 616175) ubiquitin-conjugating enz ( 318) 149 43.4 0.00035
NP_008950 (OMIM: 605574) ubiquitin-conjugating enz ( 179) 146 42.4 0.00037
NP_003338 (OMIM: 603721) ubiquitin-conjugating enz ( 154) 144 41.9 0.00046
NP_861517 (OMIM: 605574) ubiquitin-conjugating enz ( 140) 141 41.2 0.0007
XP_005246301 (OMIM: 604151) PREDICTED: ubiquitin-c ( 207) 141 41.3 0.00095
NP_001265483 (OMIM: 604151) ubiquitin-conjugating ( 207) 141 41.3 0.00095
NP_872619 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 141 41.3 0.00095
NP_001265484 (OMIM: 604151) ubiquitin-conjugating ( 207) 141 41.3 0.00095
NP_006348 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 141 41.3 0.00095
NP_862821 (OMIM: 602962) ubiquitin-conjugating enz ( 118) 136 39.9 0.0014
>>NP_003341 (OMIM: 603001) ubiquitin-conjugating enzyme (145 aa)
initn: 977 init1: 977 opt: 977 Z-score: 1275.0 bits: 241.9 E(85289): 2.8e-64
Smith-Waterman score: 977; 100.0% identity (100.0% similar) in 145 aa overlap (1-145:1-145)
10 20 30 40 50 60
pF1KB5 MAVSTGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAVSTGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 RIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQ
70 80 90 100 110 120
130 140
pF1KB5 ELRRLMMSKENMKLPQPPEGQTYNN
:::::::::::::::::::::::::
NP_003 ELRRLMMSKENMKLPQPPEGQTYNN
130 140
>>XP_011515885 (OMIM: 603001) PREDICTED: ubiquitin-conju (173 aa)
initn: 950 init1: 950 opt: 950 Z-score: 1239.0 bits: 235.4 E(85289): 2.8e-62
Smith-Waterman score: 950; 100.0% identity (100.0% similar) in 140 aa overlap (6-145:34-173)
10 20 30
pF1KB5 MAVSTGVKVPRNFRLLEELEEGQKGVGDGTVSWGL
::::::::::::::::::::::::::::::
XP_011 GAHVEEEETAGDKDVEEGVPFPGELVWNREGVKVPRNFRLLEELEEGQKGVGDGTVSWGL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 EDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSS
70 80 90 100 110 120
100 110 120 130 140
pF1KB5 GMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYNN
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYNN
130 140 150 160 170
>>XP_016869297 (OMIM: 603001) PREDICTED: ubiquitin-conju (142 aa)
initn: 942 init1: 942 opt: 942 Z-score: 1229.8 bits: 233.5 E(85289): 9.3e-62
Smith-Waterman score: 942; 100.0% identity (100.0% similar) in 139 aa overlap (7-145:4-142)
10 20 30 40 50 60
pF1KB5 MAVSTGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPRVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYEN
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 RIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQ
60 70 80 90 100 110
130 140
pF1KB5 ELRRLMMSKENMKLPQPPEGQTYNN
:::::::::::::::::::::::::
XP_016 ELRRLMMSKENMKLPQPPEGQTYNN
120 130 140
>>NP_001027459 (OMIM: 602995) ubiquitin-conjugating enzy (147 aa)
initn: 920 init1: 881 opt: 886 Z-score: 1156.9 bits: 220.0 E(85289): 1.1e-57
Smith-Waterman score: 886; 89.1% identity (95.2% similar) in 147 aa overlap (1-145:1-147)
10 20 30 40 50
pF1KB5 MAVSTG--VKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNY
::..:: :::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_001 MAATTGSGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 ENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVV
::::::::.::::::::::: :::::::::::.:.:.:.:: :.: ::::::::::::::
NP_001 ENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVV
70 80 90 100 110 120
120 130 140
pF1KB5 LQELRRLMMSKENMKLPQPPEGQTYNN
::::::::::::::::::::::: :.:
NP_001 LQELRRLMMSKENMKLPQPPEGQCYSN
130 140
>>NP_001244322 (OMIM: 602995) ubiquitin-conjugating enzy (170 aa)
initn: 906 init1: 881 opt: 881 Z-score: 1149.5 bits: 218.9 E(85289): 2.7e-57
Smith-Waterman score: 881; 91.4% identity (96.4% similar) in 140 aa overlap (6-145:31-170)
10 20 30
pF1KB5 MAVSTGVKVPRNFRLLEELEEGQKGVGDGTVSWGL
::::::::::::::::::::::::::::::
NP_001 MPGEVQASYLKSQSKLSDEGRLEPRKFHCKGVKVPRNFRLLEELEEGQKGVGDGTVSWGL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 EDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSS
::::::::::::::::::::: :::::::::.::::::::::: :::::::::::.:.:.
NP_001 EDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSN
70 80 90 100 110 120
100 110 120 130 140
pF1KB5 GMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYNN
:.:: :.: ::::::::::::::::::::::::::::::::::::: :.:
NP_001 GVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN
130 140 150 160 170
>>NP_954595 (OMIM: 602995) ubiquitin-conjugating enzyme (170 aa)
initn: 906 init1: 881 opt: 881 Z-score: 1149.5 bits: 218.9 E(85289): 2.7e-57
Smith-Waterman score: 881; 91.4% identity (96.4% similar) in 140 aa overlap (6-145:31-170)
10 20 30
pF1KB5 MAVSTGVKVPRNFRLLEELEEGQKGVGDGTVSWGL
::::::::::::::::::::::::::::::
NP_954 MPGEVQASYLKSQSKLSDEGRLEPRKFHCKGVKVPRNFRLLEELEEGQKGVGDGTVSWGL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 EDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSS
::::::::::::::::::::: :::::::::.::::::::::: :::::::::::.:.:.
NP_954 EDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSN
70 80 90 100 110 120
100 110 120 130 140
pF1KB5 GMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYNN
:.:: :.: ::::::::::::::::::::::::::::::::::::: :.:
NP_954 GVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN
130 140 150 160 170
>>NP_068823 (OMIM: 602995) ubiquitin-conjugating enzyme (170 aa)
initn: 906 init1: 881 opt: 881 Z-score: 1149.5 bits: 218.9 E(85289): 2.7e-57
Smith-Waterman score: 881; 91.4% identity (96.4% similar) in 140 aa overlap (6-145:31-170)
10 20 30
pF1KB5 MAVSTGVKVPRNFRLLEELEEGQKGVGDGTVSWGL
::::::::::::::::::::::::::::::
NP_068 MPGEVQASYLKSQSKLSDEGRLEPRKFHCKGVKVPRNFRLLEELEEGQKGVGDGTVSWGL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 EDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSS
::::::::::::::::::::: :::::::::.::::::::::: :::::::::::.:.:.
NP_068 EDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSN
70 80 90 100 110 120
100 110 120 130 140
pF1KB5 GMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYNN
:.:: :.: ::::::::::::::::::::::::::::::::::::: :.:
NP_068 GVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN
130 140 150 160 170
>>NP_001244324 (OMIM: 602995) ubiquitin-conjugating enzy (144 aa)
initn: 900 init1: 862 opt: 877 Z-score: 1145.3 bits: 217.9 E(85289): 4.7e-57
Smith-Waterman score: 877; 89.0% identity (95.9% similar) in 145 aa overlap (1-145:1-144)
10 20 30 40 50 60
pF1KB5 MAVSTGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYEN
::..:: .:::::::::::::::::::::::::::::::::::::::::::::::: :::
NP_001 MAATTG-SVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYEN
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 RIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQ
::::::.::::::::::: :::::::::::.:.:.:.:: :.: ::::::::::::::::
NP_001 RIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQ
60 70 80 90 100 110
130 140
pF1KB5 ELRRLMMSKENMKLPQPPEGQTYNN
::::::::::::::::::::: :.:
NP_001 ELRRLMMSKENMKLPQPPEGQCYSN
120 130 140
>>XP_005251357 (OMIM: 603001) PREDICTED: ubiquitin-conju (105 aa)
initn: 711 init1: 711 opt: 711 Z-score: 931.9 bits: 177.9 E(85289): 3.6e-45
Smith-Waterman score: 711; 100.0% identity (100.0% similar) in 105 aa overlap (41-145:1-105)
20 30 40 50 60 70
pF1KB5 RNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECG
::::::::::::::::::::::::::::::
XP_005 MTLTRWTGMIIGPPRTNYENRIYSLKVECG
10 20 30
80 90 100 110 120 130
pF1KB5 PKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKE
40 50 60 70 80 90
140
pF1KB5 NMKLPQPPEGQTYNN
:::::::::::::::
XP_005 NMKLPQPPEGQTYNN
100
>>NP_001244327 (OMIM: 602995) ubiquitin-conjugating enzy (105 aa)
initn: 667 init1: 642 opt: 642 Z-score: 842.3 bits: 161.3 E(85289): 3.5e-40
Smith-Waterman score: 642; 88.6% identity (95.2% similar) in 105 aa overlap (41-145:1-105)
20 30 40 50 60 70
pF1KB5 RNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECG
:::::::::::::::: :::::::::.:::
NP_001 MTLTRWTGMIIGPPRTIYENRIYSLKIECG
10 20 30
80 90 100 110 120 130
pF1KB5 PKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKE
:::::::: :::::::::::.:.:.:.:: :.: ::::::::::::::::::::::::::
NP_001 PKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKE
40 50 60 70 80 90
140
pF1KB5 NMKLPQPPEGQTYNN
::::::::::: :.:
NP_001 NMKLPQPPEGQCYSN
100
145 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 06:28:56 2016 done: Sat Nov 5 06:28:57 2016
Total Scan time: 4.440 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]