FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5220, 702 aa 1>>>pF1KB5220 702 - 702 aa - 702 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.1276+/-0.000631; mu= -21.8919+/- 0.039 mean_var=551.4412+/-113.486, 0's: 0 Z-trim(117.3): 260 B-trim: 0 in 0/54 Lambda= 0.054617 statistics sampled from 28935 (29196) to 28935 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.342), width: 16 Scan time: 13.160 The best scores are: opt bits E(85289) NP_001287721 (OMIM: 604683) kinesin-like protein K ( 702) 4519 371.8 5e-102 NP_008985 (OMIM: 604683) kinesin-like protein KIF3 ( 699) 4483 369.0 3.6e-101 XP_016864484 (OMIM: 604683) PREDICTED: kinesin-lik ( 700) 4422 364.2 1e-99 XP_016864485 (OMIM: 604683) PREDICTED: kinesin-lik ( 697) 4386 361.3 7.2e-99 XP_006714589 (OMIM: 604683) PREDICTED: kinesin-lik ( 724) 2716 229.7 3e-59 NP_001287720 (OMIM: 604683) kinesin-like protein K ( 726) 2716 229.7 3e-59 NP_004789 (OMIM: 603754) kinesin-like protein KIF3 ( 747) 2191 188.4 8.8e-47 XP_005246008 (OMIM: 605037) PREDICTED: kinesin-lik ( 984) 1486 132.9 5.7e-30 XP_005246007 (OMIM: 605037) PREDICTED: kinesin-lik ( 985) 1486 132.9 5.7e-30 XP_011540147 (OMIM: 605037) PREDICTED: kinesin-lik ( 992) 1486 132.9 5.8e-30 XP_011540146 (OMIM: 605037) PREDICTED: kinesin-lik ( 997) 1486 132.9 5.8e-30 XP_011540145 (OMIM: 605037) PREDICTED: kinesin-lik (1017) 1486 132.9 5.9e-30 NP_001116291 (OMIM: 605037) kinesin-like protein K (1028) 1486 132.9 5.9e-30 NP_065867 (OMIM: 605037) kinesin-like protein KIF1 (1029) 1486 132.9 5.9e-30 XP_011540144 (OMIM: 605037) PREDICTED: kinesin-lik (1031) 1486 132.9 5.9e-30 XP_011540143 (OMIM: 605037) PREDICTED: kinesin-lik (1038) 1486 132.9 6e-30 XP_011540142 (OMIM: 605037) PREDICTED: kinesin-lik (1042) 1486 132.9 6e-30 XP_011540141 (OMIM: 605037) PREDICTED: kinesin-lik (1043) 1486 132.9 6e-30 XP_011540140 (OMIM: 605037) PREDICTED: kinesin-lik (1062) 1486 132.9 6.1e-30 XP_011540139 (OMIM: 605037) PREDICTED: kinesin-lik (1063) 1486 132.9 6.1e-30 NP_001274141 (OMIM: 605037) kinesin-like protein K ( 929) 1153 106.7 4.3e-22 XP_011540148 (OMIM: 605037) PREDICTED: kinesin-lik ( 963) 1153 106.7 4.5e-22 NP_036442 (OMIM: 300521,300923) chromosome-associa (1232) 1002 94.9 2.1e-18 NP_001092763 (OMIM: 609184) chromosome-associated (1234) 1000 94.7 2.3e-18 NP_006603 (OMIM: 603060,611302) kinesin-like prote (1103) 971 92.4 1e-17 XP_005256481 (OMIM: 603060,611302) PREDICTED: kine (1103) 971 92.4 1e-17 XP_016859551 (OMIM: 604593,615282) PREDICTED: kine ( 957) 957 91.2 2e-17 NP_004513 (OMIM: 604593,615282) kinesin heavy chai ( 957) 957 91.2 2e-17 NP_001273663 (OMIM: 117143,616051) centromere-asso (2580) 963 92.0 3.1e-17 NP_004975 (OMIM: 602821,604187) kinesin heavy chai (1032) 950 90.7 3.1e-17 XP_011529846 (OMIM: 117143,616051) PREDICTED: cent (2676) 963 92.0 3.1e-17 XP_016863148 (OMIM: 117143,616051) PREDICTED: cent (2551) 961 91.9 3.4e-17 XP_011529851 (OMIM: 117143,616051) PREDICTED: cent (2553) 961 91.9 3.4e-17 XP_011529850 (OMIM: 117143,616051) PREDICTED: cent (2604) 961 91.9 3.4e-17 XP_011529849 (OMIM: 117143,616051) PREDICTED: cent (2605) 961 91.9 3.4e-17 XP_011529848 (OMIM: 117143,616051) PREDICTED: cent (2633) 961 91.9 3.5e-17 XP_011529847 (OMIM: 117143,616051) PREDICTED: cent (2648) 961 91.9 3.5e-17 NP_001804 (OMIM: 117143,616051) centromere-associa (2701) 961 91.9 3.5e-17 NP_904325 (OMIM: 118210,171300,256700,605995) kine (1153) 939 89.9 6.1e-17 NP_004512 (OMIM: 602809) kinesin-1 heavy chain [Ho ( 963) 931 89.2 8.2e-17 NP_055889 (OMIM: 118210,171300,256700,605995) kine (1770) 939 90.0 8.5e-17 XP_016868746 (OMIM: 607350) PREDICTED: kinesin-lik (1490) 926 88.9 1.5e-16 XP_011542763 (OMIM: 607350) PREDICTED: kinesin-lik (1783) 926 89.0 1.7e-16 XP_011542761 (OMIM: 607350) PREDICTED: kinesin-lik (1783) 926 89.0 1.7e-16 XP_011542762 (OMIM: 607350) PREDICTED: kinesin-lik (1783) 926 89.0 1.7e-16 XP_005273515 (OMIM: 607350) PREDICTED: kinesin-lik (1805) 926 89.0 1.8e-16 NP_056069 (OMIM: 607350) kinesin-like protein KIF1 (1826) 926 89.0 1.8e-16 XP_011542760 (OMIM: 607350) PREDICTED: kinesin-lik (1826) 926 89.0 1.8e-16 XP_011542759 (OMIM: 607350) PREDICTED: kinesin-lik (1847) 926 89.0 1.8e-16 NP_001099038 (OMIM: 605433) kinesin-like protein K (1749) 907 87.5 4.8e-16 >>NP_001287721 (OMIM: 604683) kinesin-like protein KIF3A (702 aa) initn: 4519 init1: 4519 opt: 4519 Z-score: 1952.6 bits: 371.8 E(85289): 5e-102 Smith-Waterman score: 4519; 100.0% identity (100.0% similar) in 702 aa overlap (1-702:1-702) 10 20 30 40 50 60 pF1KB5 MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 IKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 RQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRDQAGKKKVSPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRDQAGKKKVSPD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 KMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 KVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 EAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 RDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKEKDPFEVDLSHVYLAYTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKEKDPFEVDLSHVYLAYTE 610 620 630 640 650 660 670 680 690 700 pF1KB5 ESLRQSLMKLERPRTSKGKARPKTGRRKRSAKPETVIDSLLQ :::::::::::::::::::::::::::::::::::::::::: NP_001 ESLRQSLMKLERPRTSKGKARPKTGRRKRSAKPETVIDSLLQ 670 680 690 700 >>NP_008985 (OMIM: 604683) kinesin-like protein KIF3A is (699 aa) initn: 2746 init1: 2653 opt: 4483 Z-score: 1937.3 bits: 369.0 E(85289): 3.6e-101 Smith-Waterman score: 4483; 99.6% identity (99.6% similar) in 702 aa overlap (1-702:1-699) 10 20 30 40 50 60 pF1KB5 MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 GIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 IKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 IKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 VRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 RQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRDQAGKKKVSPD ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::: NP_008 RQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRR---GKKKVSPD 370 380 390 400 410 430 440 450 460 470 480 pF1KB5 KMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 KMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEK 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB5 KVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 KVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQE 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB5 EAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 EAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIP 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB5 RDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKEKDPFEVDLSHVYLAYTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 RDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKEKDPFEVDLSHVYLAYTE 600 610 620 630 640 650 670 680 690 700 pF1KB5 ESLRQSLMKLERPRTSKGKARPKTGRRKRSAKPETVIDSLLQ :::::::::::::::::::::::::::::::::::::::::: NP_008 ESLRQSLMKLERPRTSKGKARPKTGRRKRSAKPETVIDSLLQ 660 670 680 690 >>XP_016864484 (OMIM: 604683) PREDICTED: kinesin-like pr (700 aa) initn: 4422 init1: 4422 opt: 4422 Z-score: 1911.4 bits: 364.2 E(85289): 1e-99 Smith-Waterman score: 4422; 100.0% identity (100.0% similar) in 686 aa overlap (1-686:1-686) 10 20 30 40 50 60 pF1KB5 MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 IKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 RQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRDQAGKKKVSPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRDQAGKKKVSPD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 KMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 KVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 EAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 RDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKEKDPFEVDLSHVYLAYTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKEKDPFEVDLSHVYLAYTE 610 620 630 640 650 660 670 680 690 700 pF1KB5 ESLRQSLMKLERPRTSKGKARPKTGRRKRSAKPETVIDSLLQ :::::::::::::::::::::::::: XP_016 ESLRQSLMKLERPRTSKGKARPKTGRSSGAMVSSFIKRYH 670 680 690 700 >>XP_016864485 (OMIM: 604683) PREDICTED: kinesin-like pr (697 aa) initn: 2746 init1: 2653 opt: 4386 Z-score: 1896.0 bits: 361.3 E(85289): 7.2e-99 Smith-Waterman score: 4386; 99.6% identity (99.6% similar) in 686 aa overlap (1-686:1-683) 10 20 30 40 50 60 pF1KB5 MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 IKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 RQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRDQAGKKKVSPD ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::: XP_016 RQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRR---GKKKVSPD 370 380 390 400 410 430 440 450 460 470 480 pF1KB5 KMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEK 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB5 KVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQE 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB5 EAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIP 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB5 RDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKEKDPFEVDLSHVYLAYTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKEKDPFEVDLSHVYLAYTE 600 610 620 630 640 650 670 680 690 700 pF1KB5 ESLRQSLMKLERPRTSKGKARPKTGRRKRSAKPETVIDSLLQ :::::::::::::::::::::::::: XP_016 ESLRQSLMKLERPRTSKGKARPKTGRSSGAMVSSFIKRYH 660 670 680 690 >>XP_006714589 (OMIM: 604683) PREDICTED: kinesin-like pr (724 aa) initn: 4444 init1: 2652 opt: 2716 Z-score: 1184.7 bits: 229.7 E(85289): 3e-59 Smith-Waterman score: 4358; 96.5% identity (96.6% similar) in 710 aa overlap (1-686:1-710) 10 20 30 40 50 60 pF1KB5 MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 IKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL 310 320 330 340 350 360 370 380 390 400 pF1KB5 RQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRR----------- ::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGSSSSSSSDST 370 380 390 400 410 420 410 420 430 440 450 pF1KB5 -------------DQAGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEK .:::::::::::::::::::::::::::::::::::::::::::::: XP_006 CSVIEKPLDKFLPNQAGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEK 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB5 REKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 REKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQ 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB5 LRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEG 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB5 LLENIRQLSRELRLQMLIIDNFIPRDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLENIRQLSRELRLQMLIIDNFIPRDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQT 610 620 630 640 650 660 640 650 660 670 680 690 pF1KB5 PVPDKKEKDPFEVDLSHVYLAYTEESLRQSLMKLERPRTSKGKARPKTGRRKRSAKPETV :::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PVPDKKEKDPFEVDLSHVYLAYTEESLRQSLMKLERPRTSKGKARPKTGRSSGAMVSSFI 670 680 690 700 710 720 700 pF1KB5 IDSLLQ XP_006 KRYH >>NP_001287720 (OMIM: 604683) kinesin-like protein KIF3A (726 aa) initn: 4541 init1: 2652 opt: 2716 Z-score: 1184.6 bits: 229.7 E(85289): 3e-59 Smith-Waterman score: 4455; 96.6% identity (96.7% similar) in 726 aa overlap (1-702:1-726) 10 20 30 40 50 60 pF1KB5 MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 IKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL 310 320 330 340 350 360 370 380 390 400 pF1KB5 RQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRR----------- ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGSSSSSSSDST 370 380 390 400 410 420 410 420 430 440 450 pF1KB5 -------------DQAGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEK .:::::::::::::::::::::::::::::::::::::::::::::: NP_001 CSVIEKPLDKFLPNQAGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEK 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB5 REKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQ 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB5 LRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEG 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB5 LLENIRQLSRELRLQMLIIDNFIPRDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLENIRQLSRELRLQMLIIDNFIPRDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQT 610 620 630 640 650 660 640 650 660 670 680 690 pF1KB5 PVPDKKEKDPFEVDLSHVYLAYTEESLRQSLMKLERPRTSKGKARPKTGRRKRSAKPETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVPDKKEKDPFEVDLSHVYLAYTEESLRQSLMKLERPRTSKGKARPKTGRRKRSAKPETV 670 680 690 700 710 720 700 pF1KB5 IDSLLQ :::::: NP_001 IDSLLQ >>NP_004789 (OMIM: 603754) kinesin-like protein KIF3B [H (747 aa) initn: 2093 init1: 1194 opt: 2191 Z-score: 960.9 bits: 188.4 E(85289): 8.8e-47 Smith-Waterman score: 2192; 49.6% identity (77.5% similar) in 710 aa overlap (8-702:3-693) 10 20 30 40 50 pF1KB5 MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTD-SSNEPPK : .: ..:.:::::::.: .::. : ..:.:: : ..:.. ...: :: NP_004 MSKLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPK 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 TFTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPEL :::::.:. ..::...:. : ::..::::.:.:::::::::::::::.::::.:. :: NP_004 TFTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 RGIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGV ::.::::: ::: ::.... . ..:::.::::::.::.::::.::::.:::.:::::.:: NP_004 RGVIPNSFDHIFTHISRSQ-NQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 YIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNM :.::::..:.... .....:..:..::::::::::::::::::::.::::::: :.::. NP_004 YVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGEN 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 HVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRN :.:.:::.::::::::::::::: :.:::::::::::::.:::::::::::::::.:::. NP_004 HIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRD 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 SKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDAL ::::::::::::::.::.: ::.:::.:: .::..:::::::::::::: :.:::::::: NP_004 SKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDAL 300 310 320 330 340 350 360 370 380 390 400 pF1KB5 LRQFQKEIEELKKKLE----------EGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRR ::.::.:: .:: .:: : .. .:.. .:.::...: ::.::.. . NP_004 LREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEE----GEEGEEEGDDK 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB5 DQAGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQ : : :.: :.. :..:. .. ::. . : ::. .:: . .. . NP_004 D---------DYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAE 420 430 440 450 460 470 480 490 500 510 520 pF1KB5 SLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERL : :..:.:.:..::: ... ...::.:.::.. .:. :...: .......: ...: : NP_004 MLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETL 470 480 490 500 510 520 530 540 550 560 570 580 pF1KB5 DIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELR ...: :.:::.:.. :::::::... :.:.:.:. :::.:: .: . : .. .:.:::. NP_004 ELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELK 530 540 550 560 570 580 590 600 610 620 630 640 pF1KB5 LQMLIIDNFIPRDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKEKDPFEV :. :::.:::: . . : : . ..:. .:.:. .. :.. . :: : :. NP_004 LKHLIIENFIPLEEKSKIMNRAFFDEEEDHWKLHPITRLENQQMMKRPVSAVGYKRPLSQ 590 600 610 620 630 640 650 660 670 680 690 700 pF1KB5 DLSHVYLAYTEESLRQS---LMKLERP-RTSKGKARPKTGRRKRSAKPETVIDSLLQ .. : : :..:. : ::.. : . : ....:. :: NP_004 HARMSMMIRPEARYRAENIVLLELDMPSRTTRDYEGPAI-----APKVQAALDAALQDED 650 660 670 680 690 NP_004 EIQVDASSFESTANKKSKARPKSGRKSGSSSSSSGTPASQLYPQSRGLVPK 700 710 720 730 740 >>XP_005246008 (OMIM: 605037) PREDICTED: kinesin-like pr (984 aa) initn: 1546 init1: 1045 opt: 1486 Z-score: 659.0 bits: 132.9 E(85289): 5.7e-30 Smith-Waterman score: 1486; 51.7% identity (75.7% similar) in 489 aa overlap (13-494:4-485) 10 20 30 40 50 60 pF1KB5 MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKT . :::::::::.:.::. . . .:.:: :. ... ...:::: XP_005 MASEAVKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR :::: .. . ..:: : :....: ::::::::::::::.::.:::.:. : : XP_005 FTFDGAYHVDHVTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 GIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVY :::: .: :.: . :: .:.::::.::::::::.:::::: : :.::.::.:. ::: XP_005 GIIPRAFEHVFESVQCAE-NTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKGVY 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 IKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMH .: :: ..:... . ..:: : :::::: : ::. :::::.::::.:: : :. : XP_005 VKGLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDH 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 VRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNS .: :::.::::::::::.::::::.:::::::::::::.:::::::::::. :::::.: XP_005 LRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDS 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL :::::::::::::.::.: : ..::: :::::.::::::::::::.:: ::::::::::: XP_005 KLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALL 300 310 320 330 340 350 370 380 390 400 410 pF1KB5 RQFQKEIEELKKKLEEGEEISGSDISG--SEEDDDEEGEVGEDGEKRKK-RRDQAGKKKV :..:.::..:: : . ..: :..:. :.. . .: : . ..: ..:.. XP_005 REYQEEIKKLKAILTQ--QMSPSSLSALLSRQVPPDPVQVEEKLLPQPVIQHDVEAEKQL 360 370 380 390 400 420 430 440 450 460 470 pF1KB5 SPDKMIEMQAKIDEERKA-LETKLDMEEE---ERNKARAELEKREKDLLKAQQEHQSLLE ... : :.. . :: :.. .::. ::. ..: :..: : : ...:. XP_005 IREEYEERLARLKADYKAEQESRARLEEDITAMRNSYDVRLSTLEENLRK---ETEAVLQ 410 420 430 440 450 460 480 490 500 510 520 530 pF1KB5 KLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEE ...: : ... ... ..:: XP_005 -VGVLYKAEVMSRAEFASSAEYPPAFQYETVVKPKVFSTTDTLPSDDVSKTQVSSRFAEL 470 480 490 500 510 520 >>XP_005246007 (OMIM: 605037) PREDICTED: kinesin-like pr (985 aa) initn: 1546 init1: 1045 opt: 1486 Z-score: 659.0 bits: 132.9 E(85289): 5.7e-30 Smith-Waterman score: 1486; 51.7% identity (75.7% similar) in 489 aa overlap (13-494:4-485) 10 20 30 40 50 60 pF1KB5 MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKT . :::::::::.:.::. . . .:.:: :. ... ...:::: XP_005 MASEAVKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR :::: .. . ..:: : :....: ::::::::::::::.::.:::.:. : : XP_005 FTFDGAYHVDHVTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 GIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVY :::: .: :.: . :: .:.::::.::::::::.:::::: : :.::.::.:. ::: XP_005 GIIPRAFEHVFESVQCAE-NTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKGVY 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 IKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMH .: :: ..:... . ..:: : :::::: : ::. :::::.::::.:: : :. : XP_005 VKGLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDH 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 VRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNS .: :::.::::::::::.::::::.:::::::::::::.:::::::::::. :::::.: XP_005 LRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDS 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL :::::::::::::.::.: : ..::: :::::.::::::::::::.:: ::::::::::: XP_005 KLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALL 300 310 320 330 340 350 370 380 390 400 410 pF1KB5 RQFQKEIEELKKKLEEGEEISGSDISG--SEEDDDEEGEVGEDGEKRKK-RRDQAGKKKV :..:.::..:: : . ..: :..:. :.. . .: : . ..: ..:.. XP_005 REYQEEIKKLKAILTQ--QMSPSSLSALLSRQVPPDPVQVEEKLLPQPVIQHDVEAEKQL 360 370 380 390 400 420 430 440 450 460 470 pF1KB5 SPDKMIEMQAKIDEERKA-LETKLDMEEE---ERNKARAELEKREKDLLKAQQEHQSLLE ... : :.. . :: :.. .::. ::. ..: :..: : : ...:. XP_005 IREEYEERLARLKADYKAEQESRARLEEDITAMRNSYDVRLSTLEENLRK---ETEAVLQ 410 420 430 440 450 460 480 490 500 510 520 530 pF1KB5 KLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEE ...: : ... ... ..:: XP_005 -VGVLYKAEVMSRAEFASSAEYPPAFQYETVVKPKVFSTTDTLPSDDVSKTQVSSRFAEL 470 480 490 500 510 520 >>XP_011540147 (OMIM: 605037) PREDICTED: kinesin-like pr (992 aa) initn: 1546 init1: 1045 opt: 1486 Z-score: 659.0 bits: 132.9 E(85289): 5.8e-30 Smith-Waterman score: 1486; 51.7% identity (75.7% similar) in 489 aa overlap (13-494:4-485) 10 20 30 40 50 60 pF1KB5 MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKT . :::::::::.:.::. . . .:.:: :. ... ...:::: XP_011 MASEAVKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR :::: .. . ..:: : :....: ::::::::::::::.::.:::.:. : : XP_011 FTFDGAYHVDHVTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 GIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVY :::: .: :.: . :: .:.::::.::::::::.:::::: : :.::.::.:. ::: XP_011 GIIPRAFEHVFESVQCAE-NTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKGVY 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 IKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMH .: :: ..:... . ..:: : :::::: : ::. :::::.::::.:: : :. : XP_011 VKGLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDH 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 VRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNS .: :::.::::::::::.::::::.:::::::::::::.:::::::::::. :::::.: XP_011 LRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDS 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL :::::::::::::.::.: : ..::: :::::.::::::::::::.:: ::::::::::: XP_011 KLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALL 300 310 320 330 340 350 370 380 390 400 410 pF1KB5 RQFQKEIEELKKKLEEGEEISGSDISG--SEEDDDEEGEVGEDGEKRKK-RRDQAGKKKV :..:.::..:: : . ..: :..:. :.. . .: : . ..: ..:.. XP_011 REYQEEIKKLKAILTQ--QMSPSSLSALLSRQVPPDPVQVEEKLLPQPVIQHDVEAEKQL 360 370 380 390 400 420 430 440 450 460 470 pF1KB5 SPDKMIEMQAKIDEERKA-LETKLDMEEE---ERNKARAELEKREKDLLKAQQEHQSLLE ... : :.. . :: :.. .::. ::. ..: :..: : : ...:. XP_011 IREEYEERLARLKADYKAEQESRARLEEDITAMRNSYDVRLSTLEENLRK---ETEAVLQ 410 420 430 440 450 460 480 490 500 510 520 530 pF1KB5 KLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEE ...: : ... ... ..:: XP_011 -VGVLYKAEVMSRAEFASSAEYPPAFQYETVVKPKVFSTTDTLPSDDVSKTQVSSRFAEL 470 480 490 500 510 520 702 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:26:55 2016 done: Fri Nov 4 03:26:57 2016 Total Scan time: 13.160 Total Display time: 0.180 Function used was FASTA [36.3.4 Apr, 2011]