FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5228, 473 aa
  1>>>pF1KB5228 473 - 473 aa - 473 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.9943+/-0.00102; mu= 3.5235+/- 0.061
 mean_var=278.3109+/-55.615, 0's: 0 Z-trim(114.7): 138  B-trim: 0 in 0/52
 Lambda= 0.076879
 statistics sampled from 15094 (15233) to 15094 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.785), E-opt: 0.2 (0.468), width:  16
 Scan time:  3.800

The best scores are:                                      opt bits E(32554)
CCDS13777.1 RTN4R gene_id:65078|Hs108|chr22        ( 473) 3316 381.0 1.5e-105
CCDS7957.1 RTN4RL2 gene_id:349667|Hs108|chr11      ( 420) 1066 131.3 1.9e-30
CCDS45569.1 RTN4RL1 gene_id:146760|Hs108|chr17     ( 441) 1027 127.0 3.9e-29


>>CCDS13777.1 RTN4R gene_id:65078|Hs108|chr22             (473 aa)
 initn: 3316 init1: 3316 opt: 3316  Z-score: 2008.3  bits: 381.0 E(32554): 1.5e-105
Smith-Waterman score: 3316; 100.0% identity (100.0% similar) in 473 aa overlap (1-473:1-473)

               10        20        30        40        50        60
pF1KB5 MKRASAGGSRLLAWVLWLQAWQVAAPCPGACVCYNEPKVTTSCPQQGLQAVPVGIPAASQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MKRASAGGSRLLAWVLWLQAWQVAAPCPGACVCYNEPKVTTSCPQQGLQAVPVGIPAASQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 RIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 RIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 VDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 VDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 THLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 THLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 LPTEALAPLRALQYLRLNDNPWVCDCRARPLWAWLQKFRGSSSEVPCSLPQRLAGRDLKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LPTEALAPLRALQYLRLNDNPWVCDCRARPLWAWLQKFRGSSSEVPCSLPQRLAGRDLKR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 LAANDLQGCAVATGPYHPIWTGRATDEEPLGLPKCCQPDAADKASVLEPGRPASAGNALK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LAANDLQGCAVATGPYHPIWTGRATDEEPLGLPKCCQPDAADKASVLEPGRPASAGNALK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 GRVPPGDSPPGNGSGPRHINDSPFGTLPGSAEPPLTAVRPEGSEPPGFPTSGPRRRPGCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 GRVPPGDSPPGNGSGPRHINDSPFGTLPGSAEPPLTAVRPEGSEPPGFPTSGPRRRPGCS
              370       380       390       400       410       420

              430       440       450       460       470   
pF1KB5 RKNRTRSHCRLGQAGSGGGGTGDSEGSGALPSLTCSLTPLGLALVLWTVLGPC
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 RKNRTRSHCRLGQAGSGGGGTGDSEGSGALPSLTCSLTPLGLALVLWTVLGPC
              430       440       450       460       470   

>>CCDS7957.1 RTN4RL2 gene_id:349667|Hs108|chr11           (420 aa)
 initn: 973 init1: 895 opt: 1066  Z-score: 660.2  bits: 131.3 E(32554): 1.9e-30
Smith-Waterman score: 1066; 46.8% identity (68.3% similar) in 385 aa overlap (15-394:18-394)

                  10        20         30        40        50      
pF1KB5    MKRASAGGSRLLAWVLWLQAWQVAAP-CPGACVCYNEPKVTTSCPQQGLQAVPVGIP
                        .: : :  .::: ::  :.::. :  :.::  .....::...:
CCDS79 MLPGLRRLLQAPASACLLLMLLALPLAAPSCPMLCTCYSSPP-TVSCQANNFSSVPLSLP
               10        20        30        40         50         

         60        70        80        90       100       110      
pF1KB5 AASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNA
        ..::.::..: :  .  ..: .  ::  ::: :: :. :  ..:  :  ::.:::.:: 
CCDS79 PSTQRLFLQNNLIRTLRPGTFGS--NLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNR
      60        70        80          90       100       110       

        120       130       140       150       160       170      
pF1KB5 QLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRD
       .:::..: ::.:: ::..::: :: :. :  ..::::..:::::::.:.:  : :: : :
CCDS79 HLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFAD
       120       130       140       150       160       170       

        180       190       200       210       220       230      
pF1KB5 LGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFAN
       :.::.::::::::.  . :..:::: :::::::: ::.  ::  ::: :.::  :::: :
CCDS79 LANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNN
       180       190       200       210       220       230       

        240       250       260       270       280       290      
pF1KB5 NLSALPTEALAPLRALQYLRLNDNPWVCDCRARPLWAWLQKFRGSSSEVPCSLPQRLAGR
       .:..:: :::: : .:..:::: :::.:::::::::::.:. : :::.: :. : .  ::
CCDS79 SLASLPGEALADLPSLEFLRLNANPWACDCRARPLWAWFQRARVSSSDVTCATPPERQGR
       240       250       260       270       280       290       

        300       310         320       330       340       350    
pF1KB5 DLKRLAANDLQGCAVATGPYHPI--WTGRATDEEPLGLPKCCQPDAADKASVLEPGRPAS
       ::. :   :.:.:  :. : .:     : .....  :. .   : :    :.:    :: 
CCDS79 DLRALREADFQACPPAA-PTRPGSRARGNSSSNHLYGVAEAGAPPA--DPSTLYRDLPAE
       300       310        320       330       340         350    

          360       370       380       390         400       410  
pF1KB5 AGNALKGRVPPGDSPPGNGSGPRHINDSPFGTLPGSA--EPPLTAVRPEGSEPPGFPTSG
        . . .:   : ..   .: : .  ..      ::.:   ::                  
CCDS79 DSRGRQGGDAPTEDDYWGGYGGE--DQRGEQMCPGAACQAPPDSRGPALSAGLPSPLLCL
          360       370         380       390       400       410  

            420       430       440       450       460       470  
pF1KB5 PRRRPGCSRKNRTRSHCRLGQAGSGGGGTGDSEGSGALPSLTCSLTPLGLALVLWTVLGP
                                                                   
CCDS79 LLLVPHHL                                                    
            420                                                    

>>CCDS45569.1 RTN4RL1 gene_id:146760|Hs108|chr17          (441 aa)
 initn: 1019 init1: 872 opt: 1027  Z-score: 636.6  bits: 127.0 E(32554): 3.9e-29
Smith-Waterman score: 1102; 45.4% identity (64.9% similar) in 416 aa overlap (27-436:25-421)

               10        20        30        40        50        60
pF1KB5 MKRASAGGSRLLAWVLWLQAWQVAAPCPGACVCYNEPKVTTSCPQQGLQAVPVGIPAASQ
                                 ::  ::::  : .:.::  ... :.: :::. :.
CCDS45   MLRKGCCVELLLLLVAAELPLGGGCPRDCVCYPAP-MTVSCQAHNFAAIPEGIPVDSE
                 10        20        30         40        50       

               70        80        90       100       110       120
pF1KB5 RIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRS
       :.::..:::. .  . :     .. ::..:: .. :  ..: :.. ::.:::.:: :::.
CCDS45 RVFLQNNRIGLLQPGHFSPA--MVTLWIYSNNITYIHPSTFEGFVHLEELDLGDNRQLRT
        60        70          80        90       100       110     

              130       140       150       160       170       180
pF1KB5 VDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNL
       . : ::.:: .::.:.: .:::. :  :.: :: .::::::::: .. : :: : :: ::
CCDS45 LAPETFQGLVKLHALYLYKCGLSALPAGVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNL
         120       130       140       150       160       170     

              190       200       210       220       230       240
pF1KB5 THLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSA
       .:::::::.. :.   .:::: .:::::::.:..  :: .::.:: :: ::.:: :.:: 
CCDS45 SHLFLHGNKLWSLGPGTFRGLVNLDRLLLHENQLQWVHHKAFHDLRRLTTLFLFNNSLSE
         180       190       200       210       220       230     

              250       260       270       280       290       300
pF1KB5 LPTEALAPLRALQYLRLNDNPWVCDCRARPLWAWLQKFRGSSSEVPCSLPQRLAGRDLKR
       :  : :::: ::..:::: ::: : :::: :: :::.:::::: :::  :    :.::: 
CCDS45 LQGECLAPLGALEFLRLNGNPWDCGCRARSLWEWLQRFRGSSSAVPCVSPGLRHGQDLKL
         240       250       260       270       280       290     

              310       320       330       340       350          
pF1KB5 LAANDLQGCAVATGPYHPIWTGRATDEEPLGLPKCCQPDAADKASVLEPGRPA-SAGNAL
       : :.:...:   :::  :      :             : : .     :  :. : :.  
CCDS45 LRAEDFRNC---TGPASPHQIKSHT---------LTTTDRAARKEHHSPHGPTRSKGHPH
         300          310                320       330       340   

     360       370        380        390       400          410    
pF1KB5 KGRVPPGDSPPG-NGSGPRHIND-SPFGTLPGSAEPPLTAVRPEGSEPPGF---PTSGPR
         :  ::   :: : ..::. :. :  :.  :.  : :    :. ..  .:   ::. :.
CCDS45 GPR--PGHRKPGKNCTNPRNRNQISKAGA--GKQAPELPDYAPDYQHKFSFDIMPTARPK
             350       360       370         380       390         

          420       430       440       450       460       470   
pF1KB5 RRPGCSRKNRTRSHCRLGQAGSGGGGTGDSEGSGALPSLTCSLTPLGLALVLWTVLGPC
       :.  :.:..  :.   . ::.:                                     
CCDS45 RKGKCARRTPIRAPSGVQQASSASSLGASLLAWTLGLAVTLR                 
     400       410       420       430       440                  




473 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 03:29:34 2016 done: Fri Nov  4 03:29:35 2016
 Total Scan time:  3.800 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]