FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5231, 710 aa
1>>>pF1KB5231 710 - 710 aa - 710 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.0498+/-0.00057; mu= 5.6158+/- 0.037
mean_var=651.9216+/-128.914, 0's: 0 Z-trim(121.4): 81 B-trim: 0 in 0/60
Lambda= 0.050232
statistics sampled from 37917 (38048) to 37917 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.446), width: 16
Scan time: 14.390
The best scores are: opt bits E(85289)
NP_005372 (OMIM: 164035) nucleolin [Homo sapiens] ( 710) 4624 350.8 1e-95
NP_006796 (OMIM: 609409) heterogeneous nuclear rib ( 305) 354 40.8 0.0096
>>NP_005372 (OMIM: 164035) nucleolin [Homo sapiens] (710 aa)
initn: 4624 init1: 4624 opt: 4624 Z-score: 1839.3 bits: 350.8 E(85289): 1e-95
Smith-Waterman score: 4624; 100.0% identity (100.0% similar) in 710 aa overlap (1-710:1-710)
10 20 30 40 50 60
pF1KB5 MVKLAKAGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MVKLAKAGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AKKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AKKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 TPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 APASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 APASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 DDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 EKALELTGLKVFGNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EKALELTGLKVFGNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 WSGESKTLVLSNLSYSATEETLQEVFEKATFIKVPQNQNGKSKGYAFIEFASFEDAKEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 WSGESKTLVLSNLSYSATEETLQEVFEKATFIKVPQNQNGKSKGYAFIEFASFEDAKEAL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 NSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFDGSVRARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFDGSVRARI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 VTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGR
610 620 630 640 650 660
670 680 690 700 710
pF1KB5 GGFGGRGGGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQGKKTKFE
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GGFGGRGGGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQGKKTKFE
670 680 690 700 710
>>NP_006796 (OMIM: 609409) heterogeneous nuclear ribonuc (305 aa)
initn: 258 init1: 158 opt: 354 Z-score: 170.2 bits: 40.8 E(85289): 0.0096
Smith-Waterman score: 354; 33.3% identity (65.3% similar) in 225 aa overlap (488-697:9-230)
460 470 480 490 500 510
pF1KB5 SISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEK----ATFIK
: ...:. ...: :. :: . .
NP_006 MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVV
10 20 30
520 530 540 550 560 570
pF1KB5 VPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGPR---GSPNARSQP
: . :. .:. ..:. ... :.: :. . . . ..: ...:. : . :.:...
NP_006 VVNPQTKRSRCFGFVTYSNVEEADAAMAA-SPHAVDGNTVELKRAVSREDSARPGAHAK-
40 50 60 70 80 90
580 590 600 610 620
pF1KB5 SKTLFVKGLSEDTTEETLKESFD--GSV-RARIVTDRETGSSKGFGFVDFNSEEDAKAAK
: ::: ::. :..: : : :. :.: .:.:..:...:...::::: :... ::
NP_006 VKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNH-DAADKA
100 110 120 130 140 150
630 640 650 660 670 680
pF1KB5 EAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGG-RGGFGGRGG-GRGG---RGGFGGRGRG
... :.:..: . : :: . :: ::: :.. ::::: :::: ..:.. : :
NP_006 AVVKFHPIQGHRVEVKKAVPKEDIYSGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGG
160 170 180 190 200 210
690 700 710
pF1KB5 GFGGRGGFRGGRGGGGDHKPQGKKTKFE
:... ::. :: :::
NP_006 GYNSYGGYGGGGGGGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGG
220 230 240 250 260 270
710 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 16:23:30 2016 done: Thu Nov 3 16:23:32 2016
Total Scan time: 14.390 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]