FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5231, 710 aa 1>>>pF1KB5231 710 - 710 aa - 710 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.0498+/-0.00057; mu= 5.6158+/- 0.037 mean_var=651.9216+/-128.914, 0's: 0 Z-trim(121.4): 81 B-trim: 0 in 0/60 Lambda= 0.050232 statistics sampled from 37917 (38048) to 37917 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.446), width: 16 Scan time: 14.390 The best scores are: opt bits E(85289) NP_005372 (OMIM: 164035) nucleolin [Homo sapiens] ( 710) 4624 350.8 1e-95 NP_006796 (OMIM: 609409) heterogeneous nuclear rib ( 305) 354 40.8 0.0096 >>NP_005372 (OMIM: 164035) nucleolin [Homo sapiens] (710 aa) initn: 4624 init1: 4624 opt: 4624 Z-score: 1839.3 bits: 350.8 E(85289): 1e-95 Smith-Waterman score: 4624; 100.0% identity (100.0% similar) in 710 aa overlap (1-710:1-710) 10 20 30 40 50 60 pF1KB5 MVKLAKAGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MVKLAKAGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 AKKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 AKKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 APASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 APASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 DDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 TEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 EKALELTGLKVFGNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 EKALELTGLKVFGNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 WSGESKTLVLSNLSYSATEETLQEVFEKATFIKVPQNQNGKSKGYAFIEFASFEDAKEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 WSGESKTLVLSNLSYSATEETLQEVFEKATFIKVPQNQNGKSKGYAFIEFASFEDAKEAL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 NSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFDGSVRARI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 NSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFDGSVRARI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 VTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGR 610 620 630 640 650 660 670 680 690 700 710 pF1KB5 GGFGGRGGGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQGKKTKFE :::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GGFGGRGGGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQGKKTKFE 670 680 690 700 710 >>NP_006796 (OMIM: 609409) heterogeneous nuclear ribonuc (305 aa) initn: 258 init1: 158 opt: 354 Z-score: 170.2 bits: 40.8 E(85289): 0.0096 Smith-Waterman score: 354; 33.3% identity (65.3% similar) in 225 aa overlap (488-697:9-230) 460 470 480 490 500 510 pF1KB5 SISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEK----ATFIK : ...:. ...: :. :: . . NP_006 MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVV 10 20 30 520 530 540 550 560 570 pF1KB5 VPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGPR---GSPNARSQP : . :. .:. ..:. ... :.: :. . . . ..: ...:. : . :.:... NP_006 VVNPQTKRSRCFGFVTYSNVEEADAAMAA-SPHAVDGNTVELKRAVSREDSARPGAHAK- 40 50 60 70 80 90 580 590 600 610 620 pF1KB5 SKTLFVKGLSEDTTEETLKESFD--GSV-RARIVTDRETGSSKGFGFVDFNSEEDAKAAK : ::: ::. :..: : : :. :.: .:.:..:...:...::::: :... :: NP_006 VKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNH-DAADKA 100 110 120 130 140 150 630 640 650 660 670 680 pF1KB5 EAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGG-RGGFGGRGG-GRGG---RGGFGGRGRG ... :.:..: . : :: . :: ::: :.. ::::: :::: ..:.. : : NP_006 AVVKFHPIQGHRVEVKKAVPKEDIYSGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGG 160 170 180 190 200 210 690 700 710 pF1KB5 GFGGRGGFRGGRGGGGDHKPQGKKTKFE :... ::. :: ::: NP_006 GYNSYGGYGGGGGGGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGG 220 230 240 250 260 270 710 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 16:23:30 2016 done: Thu Nov 3 16:23:32 2016 Total Scan time: 14.390 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]