FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5235, 509 aa 1>>>pF1KB5235 509 - 509 aa - 509 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1882+/-0.00102; mu= 13.9973+/- 0.061 mean_var=77.7216+/-15.299, 0's: 0 Z-trim(104.3): 22 B-trim: 0 in 0/51 Lambda= 0.145480 statistics sampled from 7809 (7821) to 7809 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.602), E-opt: 0.2 (0.24), width: 16 Scan time: 3.210 The best scores are: opt bits E(32554) CCDS4237.1 HARS gene_id:3035|Hs108|chr5 ( 509) 3303 703.1 1.9e-202 CCDS58976.1 HARS gene_id:3035|Hs108|chr5 ( 469) 2680 572.3 4e-163 CCDS4238.1 HARS2 gene_id:23438|Hs108|chr5 ( 506) 2466 527.4 1.4e-149 CCDS64267.1 HARS2 gene_id:23438|Hs108|chr5 ( 481) 2407 515.0 7.3e-146 CCDS58977.1 HARS gene_id:3035|Hs108|chr5 ( 449) 2187 468.8 5.5e-132 CCDS58978.1 HARS gene_id:3035|Hs108|chr5 ( 489) 2183 468.0 1.1e-131 CCDS75323.1 HARS gene_id:3035|Hs108|chr5 ( 395) 2181 467.6 1.2e-131 CCDS75324.1 HARS gene_id:3035|Hs108|chr5 ( 435) 2177 466.7 2.3e-131 CCDS42016.1 EIF2AK4 gene_id:440275|Hs108|chr15 (1649) 525 120.2 1.8e-26 >>CCDS4237.1 HARS gene_id:3035|Hs108|chr5 (509 aa) initn: 3303 init1: 3303 opt: 3303 Z-score: 3748.1 bits: 703.1 E(32554): 1.9e-202 Smith-Waterman score: 3303; 100.0% identity (100.0% similar) in 509 aa overlap (1-509:1-509) 10 20 30 40 50 60 pF1KB5 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS 430 440 450 460 470 480 490 500 pF1KB5 VTSREEVDVRREDLVEEIKRRTGQPLCIC ::::::::::::::::::::::::::::: CCDS42 VTSREEVDVRREDLVEEIKRRTGQPLCIC 490 500 >>CCDS58976.1 HARS gene_id:3035|Hs108|chr5 (469 aa) initn: 2677 init1: 2677 opt: 2680 Z-score: 3042.0 bits: 572.3 E(32554): 4e-163 Smith-Waterman score: 2943; 92.1% identity (92.1% similar) in 509 aa overlap (1-509:1-469) 10 20 30 40 50 60 pF1KB5 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ :::::::::::::::::::: CCDS58 ----------------------------------------ETLMGKYGEDSKLIYDLKDQ 70 80 130 140 150 160 170 180 pF1KB5 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB5 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB5 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB5 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB5 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB5 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS 390 400 410 420 430 440 490 500 pF1KB5 VTSREEVDVRREDLVEEIKRRTGQPLCIC ::::::::::::::::::::::::::::: CCDS58 VTSREEVDVRREDLVEEIKRRTGQPLCIC 450 460 >>CCDS4238.1 HARS2 gene_id:23438|Hs108|chr5 (506 aa) initn: 2489 init1: 2460 opt: 2466 Z-score: 2798.7 bits: 527.4 E(32554): 1.4e-149 Smith-Waterman score: 2466; 76.3% identity (93.9% similar) in 473 aa overlap (32-504:34-505) 10 20 30 40 50 60 pF1KB5 AERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKG . .::. . : .:: . : .:..::::: CCDS42 LGLLPRRAWASLLSQLLRPPCASCTGAVRCQSQVAEAV-LTSQLKAHQEKPNFIIKTPKG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQG ::: ::..:.::::..:..: :::::::. .:::.::::::: :::::: :.::::::: CCDS42 TRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGEDSGLMYDLKDQG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGN ::::::::::::::::::::::. ..::::..::.::..:....:::::: ::::::::. CCDS42 GELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRESPTIVQGRYREFCQCDFDIAGQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 FDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKL :::::::::::::::::::.::.::::.:::::::.:::::.::: .::::.::::.::: CCDS42 FDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRAICSSIDKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLGD ::..:..:..::: .:::::::::::::::: :::::::::..:::.::::::::::::: CCDS42 DKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNKQALEGLGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 LKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGG ::::::::::::: :::::::::::::::::::::::::::::.:::::::.:::::::: CCDS42 LKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVLLQTPTQAGEEPLNVGSVAAGG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 RYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLL :::::::::::::.::::::::::::::: :::::... ::.:::::::.::. ::..: CCDS42 RYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQKNFL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 EERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSV .:::::..::::.:::::.:::.:::::.::.::: .:::::.::::::::.::::.::: CCDS42 QERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIRSV 430 440 450 460 470 480 490 500 pF1KB5 TSREEVDVRREDLVEEIKRRTGQPLCIC .::::: ..::..: ::..: .. CCDS42 ASREEVAIKRENFVAEIQKRLSES 490 500 >>CCDS64267.1 HARS2 gene_id:23438|Hs108|chr5 (481 aa) initn: 2434 init1: 2405 opt: 2407 Z-score: 2732.2 bits: 515.0 E(32554): 7.3e-146 Smith-Waterman score: 2407; 78.7% identity (95.5% similar) in 445 aa overlap (60-504:36-480) 30 40 50 60 70 80 pF1KB5 LIEEEVAKLLKLKAQLGPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGA .:::: ::..:.::::..:..: ::::::: CCDS64 LLPRRAWASLLSQLLRPPCASCTGAVRCQSQGTRDLSPQHMVVREKILDLVISCFKRHGA 10 20 30 40 50 60 90 100 110 120 130 140 pF1KB5 EVIDTPVFELKETLMGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKR . .:::.::::::: :::::: :.:::::::::::::::::::::::::::::. ..:: CCDS64 KGMDTPAFELKETLTEKYGEDSGLMYDLKDQGGELLSLRYDLTVPFARYLAMNKVKKMKR 70 80 90 100 110 120 150 160 170 180 190 200 pF1KB5 YHIAKVYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLV ::..::.::..:....:::::: ::::::::.:::::::::::::::::::.::.::::. CCDS64 YHVGKVWRRESPTIVQGRYREFCQCDFDIAGQFDPMIPDAECLKIMCEILSGLQLGDFLI 130 140 150 160 170 180 210 220 230 240 250 260 pF1KB5 KVNDRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGD :::::::.:::::.::: .::::.::::.:::::..:..:..::: .::::::::::::: CCDS64 KVNDRRIVDGMFAVCGVPESKFRAICSSIDKLDKMAWKDVRHEMVVKKGLAPEVADRIGD 190 200 210 220 230 240 270 280 290 300 310 320 pF1KB5 YVQQHGGVSLVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLD ::: :::::::::..:::.:::::::::::::::::::::::::: :::::::::::::: CCDS64 YVQCHGGVSLVEQMFQDPRLSQNKQALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLD 250 260 270 280 290 300 330 340 350 360 370 380 pF1KB5 YYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERI :::::::::::::::.:::::::.:::::::::::::::::::::.:::::::::::::: CCDS64 YYTGVIYEAVLLQTPTQAGEEPLNVGSVAAGGRYDGLVGMFDPKGHKVPCVGLSIGVERI 310 320 330 340 350 360 390 400 410 420 430 440 pF1KB5 FSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLL : :::::... ::.:::::::.::. ::..:.:::::..::::.:::::.:::.::::: CCDS64 FYIVEQRMKTKGEKVRTTETQVFVATPQKNFLQERLKLIAELWDSGIKAEMLYKNNPKLL 370 380 390 400 410 420 450 460 470 480 490 500 pF1KB5 NQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQPLCIC .::.::: .:::::.::::::::.::::.:::.::::: ..::..: ::..: .. CCDS64 TQLHYCESTGIPLVVIIGEQELKEGVIKIRSVASREEVAIKRENFVAEIQKRLSES 430 440 450 460 470 480 >>CCDS58977.1 HARS gene_id:3035|Hs108|chr5 (449 aa) initn: 2526 init1: 2176 opt: 2187 Z-score: 2483.1 bits: 468.8 E(32554): 5.5e-132 Smith-Waterman score: 2745; 88.2% identity (88.2% similar) in 509 aa overlap (1-509:1-449) 10 20 30 40 50 60 pF1KB5 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ :::::::::::::::::::: CCDS58 ----------------------------------------ETLMGKYGEDSKLIYDLKDQ 70 80 130 140 150 160 170 180 pF1KB5 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG :::::::::::::::::::::::::::::::::: :::::: CCDS58 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAK--------------------DFDIAG 90 100 110 120 190 200 210 220 230 240 pF1KB5 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK 130 140 150 160 170 180 250 260 270 280 290 300 pF1KB5 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG 190 200 210 220 230 240 310 320 330 340 350 360 pF1KB5 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG 250 260 270 280 290 300 370 380 390 400 410 420 pF1KB5 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL 310 320 330 340 350 360 430 440 450 460 470 480 pF1KB5 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS 370 380 390 400 410 420 490 500 pF1KB5 VTSREEVDVRREDLVEEIKRRTGQPLCIC ::::::::::::::::::::::::::::: CCDS58 VTSREEVDVRREDLVEEIKRRTGQPLCIC 430 440 >>CCDS58978.1 HARS gene_id:3035|Hs108|chr5 (489 aa) initn: 3141 init1: 2176 opt: 2183 Z-score: 2478.0 bits: 468.0 E(32554): 1.1e-131 Smith-Waterman score: 3105; 96.1% identity (96.1% similar) in 509 aa overlap (1-509:1-489) 10 20 30 40 50 60 pF1KB5 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG :::::::::::::::::::::::::::::::::: :::::: CCDS58 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAK--------------------DFDIAG 130 140 150 160 190 200 210 220 230 240 pF1KB5 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB5 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB5 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB5 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB5 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS 410 420 430 440 450 460 490 500 pF1KB5 VTSREEVDVRREDLVEEIKRRTGQPLCIC ::::::::::::::::::::::::::::: CCDS58 VTSREEVDVRREDLVEEIKRRTGQPLCIC 470 480 >>CCDS75323.1 HARS gene_id:3035|Hs108|chr5 (395 aa) initn: 2524 init1: 2176 opt: 2181 Z-score: 2477.2 bits: 467.6 E(32554): 1.2e-131 Smith-Waterman score: 2300; 77.6% identity (77.6% similar) in 509 aa overlap (1-509:1-395) 10 20 30 40 50 60 pF1KB5 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ CCDS75 ------------------------------------------------------------ 130 140 150 160 170 180 pF1KB5 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG :::::: CCDS75 ------------------------------------------------------DFDIAG 190 200 210 220 230 240 pF1KB5 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK 70 80 90 100 110 120 250 260 270 280 290 300 pF1KB5 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG 130 140 150 160 170 180 310 320 330 340 350 360 pF1KB5 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG 190 200 210 220 230 240 370 380 390 400 410 420 pF1KB5 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL 250 260 270 280 290 300 430 440 450 460 470 480 pF1KB5 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS 310 320 330 340 350 360 490 500 pF1KB5 VTSREEVDVRREDLVEEIKRRTGQPLCIC ::::::::::::::::::::::::::::: CCDS75 VTSREEVDVRREDLVEEIKRRTGQPLCIC 370 380 390 >>CCDS75324.1 HARS gene_id:3035|Hs108|chr5 (435 aa) initn: 2176 init1: 2176 opt: 2177 Z-score: 2472.0 bits: 466.7 E(32554): 2.3e-131 Smith-Waterman score: 2650; 85.5% identity (85.5% similar) in 509 aa overlap (1-509:1-435) 10 20 30 40 50 60 pF1KB5 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ :::::::::::::::::::::::::::::::::::::::: CCDS75 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELK-------------------- 70 80 90 100 130 140 150 160 170 180 pF1KB5 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG :::::: CCDS75 ------------------------------------------------------DFDIAG 190 200 210 220 230 240 pF1KB5 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK 110 120 130 140 150 160 250 260 270 280 290 300 pF1KB5 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG 170 180 190 200 210 220 310 320 330 340 350 360 pF1KB5 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG 230 240 250 260 270 280 370 380 390 400 410 420 pF1KB5 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL 290 300 310 320 330 340 430 440 450 460 470 480 pF1KB5 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS 350 360 370 380 390 400 490 500 pF1KB5 VTSREEVDVRREDLVEEIKRRTGQPLCIC ::::::::::::::::::::::::::::: CCDS75 VTSREEVDVRREDLVEEIKRRTGQPLCIC 410 420 430 >>CCDS42016.1 EIF2AK4 gene_id:440275|Hs108|chr15 (1649 aa) initn: 363 init1: 139 opt: 525 Z-score: 588.8 bits: 120.2 E(32554): 1.8e-26 Smith-Waterman score: 525; 26.4% identity (63.4% similar) in 454 aa overlap (64-501:1055-1489) 40 50 60 70 80 90 pF1KB5 EVAKLLKLKAQLGPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVID ..: : ....: ..::: :::::: . CCDS42 KAYRTMMAQIFSQRISPAIDYTYDSDILKGNFSIRTAKMQQHVCETIIRIFKRHGAVQLC 1030 1040 1050 1060 1070 1080 100 110 120 130 140 150 pF1KB5 TPVFELKETLMGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIA ::.. .. . ...: . .. :..: :. : .:: .:::::.: :.. :.::: : CCDS42 TPLLLPRNRQIYEHNEAALFM----DHSGMLVMLPFDLRIPFARYVARNNILNLKRYCIE 1090 1100 1110 1120 1130 1140 160 170 180 190 200 pF1KB5 KVYRRDNPAMTRGRYREFYQCDFDIA-GNFDPMIPDAECLKIMCEILS---SLQIGDFLV .:.: . . : . .:. .: :::. .. . ..: :: . . ::.. .:: .. . CCDS42 RVFRPRK--LDRFHPKELLECAFDIVTSTTNSFLPTAEIIYTIYEIIQEFPALQERNYSI 1150 1160 1170 1180 1190 210 220 230 240 250 260 pF1KB5 KVNDRRILDGMFAICGVSDSKFRTICSSV-DKL-DKVSWEEVKNEMVGEKGLAPEVADRI .: .: ... ::. ..:. . . : . .:.. .::. .. . . :. . :. CCDS42 YLNHTMLLKAILLHCGIPEDKLSQVYIILYDAVTEKLTRREVEAKFCNLS-LSSNSLCRL 1200 1210 1220 1230 1240 1250 270 280 290 300 310 320 pF1KB5 GDYVQQHGGVS----LVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLS ...:.: .. ...:... : . . . :: ::. . : .:: .. ..:. CCDS42 YKFIEQKGDLQDLMPTINSLIKQ-KTGIAQLVKYGLKDLEEVVGLLKKLGIKLQVLINLG 1260 1270 1280 1290 1300 1310 330 340 350 360 370 pF1KB5 LARGLDYYTGVIYEAV-LLQTPAQAGEEPLGVGSVAAGGRYDGLVGMF-DPKGR-KVPC- :. .. ..:.:.. : ... .: : : ::::::: :. .: :.. :: CCDS42 LVYKVQQHNGIIFQFVAFIKRRQRAVPEIL-----AAGGRYDLLIPQFRGPQALGPVPTA 1320 1330 1340 1350 1360 1370 380 390 400 410 420 430 pF1KB5 VGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAE .:.::....: . : . .::.. . ..::.:. . . . ..:...:: ::: :: CCDS42 IGVSIAIDKISAAVLN----MEESVTISSCDLLVVSVGQMSMSRAINLTQKLWTAGITAE 1380 1390 1400 1410 1420 440 450 460 470 480 490 pF1KB5 LLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVR--REDLVEE ..: . . . .::.. : ::.....: . .:..: ...... : . .::.. CCDS42 IMYDWSQSQEELQEYCRHHEITYVALVSDKEGSH--VKVKSFEKERQTEKRVLETELVDH 1430 1440 1450 1460 1470 1480 500 pF1KB5 IKRRTGQPLCIC . .. CCDS42 VLQKLRTKVTDERNGREASDNLAVQNLKGSFSNASGLFEIHGATVVPIVSVLAPEKLSAS 1490 1500 1510 1520 1530 1540 509 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:15:20 2016 done: Fri Nov 4 22:15:21 2016 Total Scan time: 3.210 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]