FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5241, 478 aa 1>>>pF1KB5241 478 - 478 aa - 478 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0260+/-0.000477; mu= 14.6491+/- 0.029 mean_var=82.4516+/-17.847, 0's: 0 Z-trim(110.5): 63 B-trim: 1722 in 2/52 Lambda= 0.141245 statistics sampled from 18759 (18816) to 18759 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.576), E-opt: 0.2 (0.221), width: 16 Scan time: 8.250 The best scores are: opt bits E(85289) NP_001539 (OMIM: 147690) interferon-induced protei ( 478) 3153 652.8 6.2e-187 NP_001257856 (OMIM: 147690) interferon-induced pro ( 478) 3147 651.5 1.4e-186 NP_001257857 (OMIM: 147690) interferon-induced pro ( 447) 2932 607.7 2.1e-173 NP_001257858 (OMIM: 147690) interferon-induced pro ( 447) 2932 607.7 2.1e-173 NP_001257859 (OMIM: 147690) interferon-induced pro ( 447) 2932 607.7 2.1e-173 NP_036552 (OMIM: 616135) interferon-induced protei ( 482) 1765 369.9 8.7e-102 NP_001538 (OMIM: 147040) interferon-induced protei ( 472) 1348 284.9 3.2e-76 NP_001026853 (OMIM: 604650) interferon-induced pro ( 490) 740 161.1 6.6e-39 NP_001540 (OMIM: 604650) interferon-induced protei ( 490) 740 161.1 6.6e-39 NP_001276688 (OMIM: 604650) interferon-induced pro ( 438) 633 139.2 2.2e-32 NP_001276687 (OMIM: 604650) interferon-induced pro ( 438) 633 139.2 2.2e-32 NP_055635 (OMIM: 606081) mitochondrial import rece ( 608) 171 45.2 0.00063 >>NP_001539 (OMIM: 147690) interferon-induced protein wi (478 aa) initn: 3153 init1: 3153 opt: 3153 Z-score: 3477.1 bits: 652.8 E(85289): 6.2e-187 Smith-Waterman score: 3153; 100.0% identity (100.0% similar) in 478 aa overlap (1-478:1-478) 10 20 30 40 50 60 pF1KB5 MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 QIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 ENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSIN 370 380 390 400 410 420 430 440 450 460 470 pF1KB5 SLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP 430 440 450 460 470 >>NP_001257856 (OMIM: 147690) interferon-induced protein (478 aa) initn: 3147 init1: 3147 opt: 3147 Z-score: 3470.5 bits: 651.5 E(85289): 1.4e-186 Smith-Waterman score: 3147; 99.8% identity (99.8% similar) in 478 aa overlap (1-478:1-478) 10 20 30 40 50 60 pF1KB5 MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY : :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MCTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 QIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 ENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSIN 370 380 390 400 410 420 430 440 450 460 470 pF1KB5 SLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP 430 440 450 460 470 >>NP_001257857 (OMIM: 147690) interferon-induced protein (447 aa) initn: 2932 init1: 2932 opt: 2932 Z-score: 3234.1 bits: 607.7 E(85289): 2.1e-173 Smith-Waterman score: 2932; 100.0% identity (100.0% similar) in 447 aa overlap (32-478:1-447) 10 20 30 40 50 60 pF1KB5 STNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYV :::::::::::::::::::::::::::::: NP_001 MPDLENRVLDQIEFLDTKYSVGIHNLLAYV 10 20 30 70 80 90 100 110 120 pF1KB5 KHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKV 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 ENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGY 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 AISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIE 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 EALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQ 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 IKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEE 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 NFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINS 340 350 360 370 380 390 430 440 450 460 470 pF1KB5 LKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP 400 410 420 430 440 >>NP_001257858 (OMIM: 147690) interferon-induced protein (447 aa) initn: 2932 init1: 2932 opt: 2932 Z-score: 3234.1 bits: 607.7 E(85289): 2.1e-173 Smith-Waterman score: 2932; 100.0% identity (100.0% similar) in 447 aa overlap (32-478:1-447) 10 20 30 40 50 60 pF1KB5 STNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYV :::::::::::::::::::::::::::::: NP_001 MPDLENRVLDQIEFLDTKYSVGIHNLLAYV 10 20 30 70 80 90 100 110 120 pF1KB5 KHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKV 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 ENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGY 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 AISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIE 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 EALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQ 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 IKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEE 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 NFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINS 340 350 360 370 380 390 430 440 450 460 470 pF1KB5 LKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP 400 410 420 430 440 >>NP_001257859 (OMIM: 147690) interferon-induced protein (447 aa) initn: 2932 init1: 2932 opt: 2932 Z-score: 3234.1 bits: 607.7 E(85289): 2.1e-173 Smith-Waterman score: 2932; 100.0% identity (100.0% similar) in 447 aa overlap (32-478:1-447) 10 20 30 40 50 60 pF1KB5 STNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYV :::::::::::::::::::::::::::::: NP_001 MPDLENRVLDQIEFLDTKYSVGIHNLLAYV 10 20 30 70 80 90 100 110 120 pF1KB5 KHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKV 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 ENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGY 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 AISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIE 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 EALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQ 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 IKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEE 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 NFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINS 340 350 360 370 380 390 430 440 450 460 470 pF1KB5 LKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP 400 410 420 430 440 >>NP_036552 (OMIM: 616135) interferon-induced protein wi (482 aa) initn: 1800 init1: 1016 opt: 1765 Z-score: 1948.4 bits: 369.9 E(85289): 8.7e-102 Smith-Waterman score: 1765; 57.3% identity (82.1% similar) in 464 aa overlap (10-473:9-469) 10 20 30 40 50 60 pF1KB5 MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY .: : .:.:::::.: .: .. ..:. . .:.::: :: ....::::: NP_036 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAY 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK ::::::::..::. :..::...:.::... .:::::::::.::.:::: .: ::: : : NP_036 VKHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG . :.:::::.: :..:::: :::.:::::: ::: :..::: :::.:::.:.::: . : NP_036 IGNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYI :::..:::: . . : ::: :::.:: :::::.::::.::::::: :::::::: NP_036 YAITVYRLDD-SDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYI 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMI :: : ..::: ::.::::::::::.: .::::::::::. :::: .::::.::::.:::: NP_036 EEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMI 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 QIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE :::.::...:.:... :.:..: ::::::..:.:. : :. ::: :: :.:.. .:: NP_036 QIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAE 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB5 ENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSIN . :.: : .. .... ..::.::::::::..::. .:: :::.:.:... : : : . NP_036 DIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTS 360 370 380 390 400 410 430 440 450 460 470 pF1KB5 SLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP .:::: ..: ..:::..::: :::::::::. .: ::::.: .. : ::. NP_036 ALKKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKI--DPENAEFLTALC 420 430 440 450 460 470 NP_036 ELRLSI 480 >>NP_001538 (OMIM: 147040) interferon-induced protein wi (472 aa) initn: 941 init1: 512 opt: 1348 Z-score: 1489.3 bits: 284.9 E(85289): 3.2e-76 Smith-Waterman score: 1348; 46.5% identity (76.3% similar) in 469 aa overlap (1-464:1-457) 10 20 30 40 50 60 pF1KB5 MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY :: : . .....::.::.:::::.: .. . :.:..:. . :: . .... . ::::: NP_001 MSEN-NKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAY 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK .:::::::: ::. :..::.:.:.:: .::..::::::::.::.:::::::...: :.:: NP_001 LKHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG :...:.:.:.: ::.: ::.::::::. :::::.. ::::.::::.:: :.::: ..: NP_001 VKHVCEKFSSP--YRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSG 120 130 140 150 160 170 190 200 210 220 230 pF1KB5 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQ---DEGQE-AEG ::..::::.. ..: .. :::::.:::::: :.::::::::. .::.: .:: NP_001 LAIASYRLDNWP-PSQN----AIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 EKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYK :: .:::: . . : :.: :::::::: :::.:::::::. :... :: ::: ::. NP_001 EKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYR 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 AQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPT-FEVAHLDLARMYIEAGN :...:. . .. : ..:: ..: :. :...: : . . :.: . :: .. : . NP_001 AKVFQVMNLRENGMYG--KRKLLELIGHAVAHLKKADEANDNLFRVCSI-LASLHALADQ 300 310 320 330 340 360 370 380 390 400 410 pF1KB5 HRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTR .. :: ::: . : .. . : .:..:: :: .: : . .:: :.....::.: : . NP_001 YEDAEYYFQKEFS-KELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREK 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB5 DKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVR .: ..:.:.. .: ... : :.: .:.:. .:. .:..: : ::.: NP_001 EKMKDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGLESGSLIPSASS 410 420 430 440 450 460 pF1KB5 QGP NP_001 WNGE 470 >>NP_001026853 (OMIM: 604650) interferon-induced protein (490 aa) initn: 1028 init1: 527 opt: 740 Z-score: 819.5 bits: 161.1 E(85289): 6.6e-39 Smith-Waterman score: 1225; 44.6% identity (73.0% similar) in 471 aa overlap (11-474:6-453) 10 20 30 40 50 pF1KB5 MSTNGDDHQVKDSLE----QLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHN :.::: ::.:::::.: .:. :::.:: .:::::.:.... ..: NP_001 MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYN 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 LLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQT ::::.::: :.:: ::. :..::.:.:.:: .::..::::::::.::.:::.:::..:: NP_001 LLAYIKHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQI 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 YLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPE :.:::.. :::.::: : .: :.::::::. :::: .: ::::.::::.:: :.::: NP_001 YVDKVKQTCKKFSNP--YSIEYSELDCEEGWTQLKCG-RN-ERAKVCFEKALEEKPNNPE 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 SSAGYAISAYRLDGFKLATKNH--KPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEA :.: ::. :.:: :: : :: :.::..:.::: :.::::.:::: ..:: NP_001 FSSGLAIAMYHLD-------NHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEA 180 190 200 210 220 240 250 260 270 280 290 pF1KB5 EGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLC :::...:::: . :: :.: :::::::::..:::.::....:. ::.. :.:::: : NP_001 EGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCC 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB5 YKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAG :::.. :.... ... : :.: .. . . :. . ..:.:: . :. :::. ..:. NP_001 YKAKVRQMQNTGESEASG-NKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAE-FLET- 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB5 NHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLT : .: . : : . :. : .: .:... ::. .:. : :....: . : NP_001 ------ECYQTPFN-KEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTD 350 360 370 380 390 420 430 440 450 460 470 pF1KB5 RDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERAL-RLAADFENS ... .. ... : ..: . :. :...: .:.. .: . ::. : :: : .. NP_001 KEEIKDQPQNVSENLLPQNAPNYWYLQ--GLIHKQNGDLLQAAKCYEKELGRLLRDAPSG 400 410 420 430 440 450 pF1KB5 VRQGP . NP_001 IGSIFLSASELEDGSEEMGQGAVSSSPRELLSNSEQLN 460 470 480 490 >>NP_001540 (OMIM: 604650) interferon-induced protein wi (490 aa) initn: 1028 init1: 527 opt: 740 Z-score: 819.5 bits: 161.1 E(85289): 6.6e-39 Smith-Waterman score: 1225; 44.6% identity (73.0% similar) in 471 aa overlap (11-474:6-453) 10 20 30 40 50 pF1KB5 MSTNGDDHQVKDSLE----QLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHN :.::: ::.:::::.: .:. :::.:: .:::::.:.... ..: NP_001 MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYN 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 LLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQT ::::.::: :.:: ::. :..::.:.:.:: .::..::::::::.::.:::.:::..:: NP_001 LLAYIKHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQI 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 YLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPE :.:::.. :::.::: : .: :.::::::. :::: .: ::::.::::.:: :.::: NP_001 YVDKVKQTCKKFSNP--YSIEYSELDCEEGWTQLKCG-RN-ERAKVCFEKALEEKPNNPE 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 SSAGYAISAYRLDGFKLATKNH--KPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEA :.: ::. :.:: :: : :: :.::..:.::: :.::::.:::: ..:: NP_001 FSSGLAIAMYHLD-------NHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEA 180 190 200 210 220 240 250 260 270 280 290 pF1KB5 EGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLC :::...:::: . :: :.: :::::::::..:::.::....:. ::.. :.:::: : NP_001 EGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCC 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB5 YKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAG :::.. :.... ... : :.: .. . . :. . ..:.:: . :. :::. ..:. NP_001 YKAKVRQMQNTGESEASG-NKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAE-FLET- 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB5 NHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLT : .: . : : . :. : .: .:... ::. .:. : :....: . : NP_001 ------ECYQTPFN-KEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTD 350 360 370 380 390 420 430 440 450 460 470 pF1KB5 RDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERAL-RLAADFENS ... .. ... : ..: . :. :...: .:.. .: . ::. : :: : .. NP_001 KEEIKDQPQNVSENLLPQNAPNYWYLQ--GLIHKQNGDLLQAAKCYEKELGRLLRDAPSG 400 410 420 430 440 450 pF1KB5 VRQGP . NP_001 IGSIFLSASELEDGSEEMGQGAVSSSPRELLSNSEQLN 460 470 480 490 >>NP_001276688 (OMIM: 604650) interferon-induced protein (438 aa) initn: 883 init1: 391 opt: 633 Z-score: 702.4 bits: 139.2 E(85289): 2.2e-32 Smith-Waterman score: 1078; 43.9% identity (72.6% similar) in 424 aa overlap (54-474:1-401) 30 40 50 60 70 80 pF1KB5 ELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNEEALKSLKEAENLMQ ..:::::.::: :.:: ::. :..::.:.: NP_001 MYNLLAYIKHLDGNNEAALECLRQAEELIQ 10 20 30 90 100 110 120 130 140 pF1KB5 EEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDC .:: .::..::::::::.::.:::.:::..:: :.:::.. :::.::: : .: :.:: NP_001 QEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKVKQTCKKFSNP--YSIEYSELDC 40 50 60 70 80 150 160 170 180 190 200 pF1KB5 EEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNH--KPF ::::. :::: .: ::::.::::.:: :.::: :.: ::. :.:: :: : : NP_001 EEGWTQLKCG-RN-ERAKVCFEKALEEKPNNPEFSSGLAIAMYHLD-------NHPEKQF 90 100 110 120 130 210 220 230 240 250 260 pF1KB5 SLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFY : :.::..:.::: :.::::.:::: ..:::::...:::: . :: :.: ::::: NP_001 STDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFY 140 150 160 170 180 190 270 280 290 300 310 320 pF1KB5 RRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKM ::::..:::.::....:. ::.. :.:::: ::::.. :.... ... : :.: .. . NP_001 RRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEASG-NKEMIEAL 200 210 220 230 240 250 330 340 350 360 370 380 pF1KB5 IRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIH . :. . ..:.:: . :. :::. ..:. : .: . : : . :. : NP_001 KQYAMDYSNKALEKGLNPLNAYSDLAE-FLET-------ECYQTPFN-KEVPDAEKQQSH 260 270 280 290 300 390 400 410 420 430 440 pF1KB5 FHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLS .: .:... ::. .:. : :....: . : ... .. ... : ..: . :. NP_001 QRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYLQ 310 320 330 340 350 360 450 460 470 pF1KB5 LLGFVYKLEGNMNEALEYYERAL-RLAADFENSVRQGP :...: .:.. .: . ::. : :: : ... NP_001 --GLIHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSP 370 380 390 400 410 420 NP_001 RELLSNSEQLN 430 478 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:32:36 2016 done: Sat Nov 5 06:32:38 2016 Total Scan time: 8.250 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]