FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5258, 324 aa 1>>>pF1KB5258 324 - 324 aa - 324 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5365+/-0.000295; mu= 9.3797+/- 0.019 mean_var=200.0461+/-41.199, 0's: 0 Z-trim(124.0): 39 B-trim: 864 in 2/57 Lambda= 0.090680 statistics sampled from 44837 (44888) to 44837 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.804), E-opt: 0.2 (0.526), width: 16 Scan time: 9.270 The best scores are: opt bits E(85289) NP_004550 (OMIM: 154030) nuclease-sensitive elemen ( 324) 2259 307.0 3.3e-83 NP_057066 (OMIM: 611447) Y-box-binding protein 2 [ ( 364) 832 120.4 5.7e-27 NP_003642 (OMIM: 603437) Y-box-binding protein 3 i ( 372) 775 113.0 1e-24 XP_016875611 (OMIM: 603437) PREDICTED: Y-box-bindi ( 369) 773 112.7 1.2e-24 NP_001138898 (OMIM: 603437) Y-box-binding protein ( 303) 769 112.1 1.5e-24 XP_016875612 (OMIM: 603437) PREDICTED: Y-box-bindi ( 300) 751 109.7 7.7e-24 XP_011519173 (OMIM: 603437) PREDICTED: Y-box-bindi ( 200) 706 103.7 3.5e-22 XP_016880202 (OMIM: 611447) PREDICTED: Y-box-bindi ( 379) 569 86.0 1.3e-16 XP_011534120 (OMIM: 611044) PREDICTED: protein lin ( 258) 250 44.1 0.00037 XP_006715540 (OMIM: 611044) PREDICTED: protein lin ( 269) 250 44.1 0.00039 NP_001004317 (OMIM: 611044) protein lin-28 homolog ( 250) 244 43.3 0.00063 >>NP_004550 (OMIM: 154030) nuclease-sensitive element-bi (324 aa) initn: 2259 init1: 2259 opt: 2259 Z-score: 1614.7 bits: 307.0 E(85289): 3.3e-83 Smith-Waterman score: 2259; 100.0% identity (100.0% similar) in 324 aa overlap (1-324:1-324) 10 20 30 40 50 60 pF1KB5 MSSEAETQQPPAAPPAAPALSAADTKPGTTGSGAGSGGPGGLTSAAPAGGDKKVIATKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MSSEAETQQPPAAPPAAPALSAADTKPGTTGSGAGSGGPGGLTSAAPAGGDKKVIATKVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 EAANVTGPGGVPVQGSKYAADRNHYRRYPRRRGPPRNYQQNYQNSESGEKNEGSESAPEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EAANVTGPGGVPVQGSKYAADRNHYRRYPRRRGPPRNYQQNYQNSESGEKNEGSESAPEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 QAQQRRPYRRRRFPPYYMRRPYGRRPQYSNPPVQGEVMEGADNQGAGEQGRPVRQNMYRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QAQQRRPYRRRRFPPYYMRRPYGRRPQYSNPPVQGEVMEGADNQGAGEQGRPVRQNMYRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 YRPRFRRGPPRQRQPREDGNEEDKENQGDETQGQQPPQRRYRRNFNYRRRRPENPKPQDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 YRPRFRRGPPRQRQPREDGNEEDKENQGDETQGQQPPQRRYRRNFNYRRRRPENPKPQDG 250 260 270 280 290 300 310 320 pF1KB5 KETKAADPPAENSSAPEAEQGGAE :::::::::::::::::::::::: NP_004 KETKAADPPAENSSAPEAEQGGAE 310 320 >>NP_057066 (OMIM: 611447) Y-box-binding protein 2 [Homo (364 aa) initn: 717 init1: 571 opt: 832 Z-score: 605.2 bits: 120.4 E(85289): 5.7e-27 Smith-Waterman score: 832; 48.1% identity (66.7% similar) in 324 aa overlap (10-316:53-352) 10 20 30 pF1KB5 MSSEAETQQPPAAPPAAPALSAADTKPGTTGSGAGSGGP : :. :.::. . ::. .. : :: : NP_057 AGVVAVVVPVPAGEPQKGGGAGGGGGAASGPAAGTPSAPG----SRTPGNPAT-AVSGTP 30 40 50 60 70 40 50 60 70 80 90 pF1KB5 GGLTSAAPA--GGDKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPR : :: .:: :.: .::::::::::::::::::::::::::::::::::.:::: NP_057 -----APPARSQADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKRNNPR 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB5 KYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSKYAADRNHYRRY-PR--RRGP :.:::::::::::::::::::::::.::::::::::.::.:: .: . ::. :: .: NP_057 KFLRSVGDGETVEFDVVEGEKGAEATNVTGPGGVPVKGSRYAPNRRKSRRFIPRPPSVAP 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB5 PRNYQQNYQNSESGEKNEGSESAPEGQAQQRRPYRRRRFPPYYMRRPYGRRPQYSNPPVQ : . .. .: ..: .. :: :: :: ::...:: . : :. :: : NP_057 PPMVAE-IPSAGTGPGSKGERAEDSGQ----RP-RRWCPPPFFYRRRFVRGPR---PPNQ 200 210 220 230 240 220 230 240 250 260 pF1KB5 GEVMEGADNQGAGEQGRPVRQNMYRG--------YRPRFRRG--P-PRQRQPREDGNEED . .::.: : . :.. .. .: .:::.:: : :::. : :. : NP_057 QQPIEGTDRVEPKETA-PLEGHQQQGDERVPPPRFRPRYRRPFRPRPRQQPTTEGGDGET 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB5 KENQGDETQGQQP-PQRRYRRNFNYRRRRPENPKPQDGKETKAADPPAENSSAPEAEQGG : .:: ..:..: ::: : . ..::: . : ::.. . .: : ..::: NP_057 KPSQGP-ADGSRPEPQRPRNRPY-FQRRRQQAPGPQQAPGPR--QPAAPETSAPVNSGDP 310 320 330 340 350 pF1KB5 AE NP_057 TTTILE 360 >>NP_003642 (OMIM: 603437) Y-box-binding protein 3 isofo (372 aa) initn: 1018 init1: 614 opt: 775 Z-score: 564.8 bits: 113.0 E(85289): 1e-24 Smith-Waterman score: 1088; 57.4% identity (71.6% similar) in 338 aa overlap (10-324:41-372) 10 20 30 pF1KB5 MSSEAETQQPPAAPPAAPALSAADTKPGTTGSGAGSGGP : :: :: :: .: . :: .. :..: NP_003 TTTTLPQAPTEAAAAAPQDPAPKSPVGSGAPQAAAPA-PAAHVAGN-PGGDAAPAATGTA 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 GGLTSAAPAGGD---KKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNP .. . :. ::.. :::.::::::::::::::::::::::::::::::::::::::::: NP_003 AAASLATAAGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNP 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 RKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSKYAADRNHYRR--YPRRRGP :::::::::::::::::::::::::::::::: ::::.::.::::: .::: : ::::: NP_003 RKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGP 130 140 150 160 170 180 160 170 180 190 200 pF1KB5 PRNYQQNYQNSESGEKNEGSESAPEGQ-----AQQRRP-----YRRRRFPPYYMRRPYGR :::: . .. :: .. . : . : : ::: ::.::::::.. . . : NP_003 PRNYAGEEEEEGSGSSEGFDPPATDRQFSGARNQLRRPQYRPQYRQRRFPPYHVGQTFDR 190 200 210 220 230 240 210 220 230 240 250 pF1KB5 RPQYSNPP--VQ-GEVMEGADN--QGAGEQGRPVRQNMYRGYRPRFR-RGPPRQRQPRED : . : .: ::. : :. .:: :: ::..: ::::.: ::::: : NP_003 RSRVLPHPNRIQAGEIGEMKDGVPEGAQLQG-PVHRNPT--YRPRYRSRGPPRPRPAPAV 250 260 270 280 290 300 260 270 280 290 300 310 pF1KB5 GNEEDKENQGDETQGQQPPQRR-YRRNFNYRRR-RPENPKPQDGKETKAADPPAENSSAP :. :::::: . .:: :: ::: .::::: :: : :::::.::.. :.:: :: NP_003 GEAEDKENQQATSGPNQPSVRRGYRRPYNYRRRPRPPNAPSQDGKEAKAGEAPTENP-AP 310 320 330 340 350 360 320 pF1KB5 EAEQGGAE ..:..:: NP_003 PTQQSSAE 370 >>XP_016875611 (OMIM: 603437) PREDICTED: Y-box-binding p (369 aa) initn: 996 init1: 614 opt: 773 Z-score: 563.4 bits: 112.7 E(85289): 1.2e-24 Smith-Waterman score: 1067; 57.0% identity (70.9% similar) in 337 aa overlap (10-324:41-369) 10 20 30 pF1KB5 MSSEAETQQPPAAPPAAPALSAADTKPGTTGSGAGSGGP : :: :: :: .: . :: .. :..: XP_016 TTTTLPQAPTEAAAAAPQDPAPKSPVGSGAPQAAAPA-PAAHVAGN-PGGDAAPAATGTA 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 GGLTSAAPAGGD---KKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNP .. . :. ::.. :::.::::::::::::::::::::::::::::::::::::::::: XP_016 AAASLATAAGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNP 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 RKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSKYAADRNHYRR--YPRRRGP :::::::::::::::::::::::::::::::: ::::.::.::::: .::: : ::::: XP_016 RKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGP 130 140 150 160 170 180 160 170 180 190 200 pF1KB5 PRNYQQNYQNSESGEKNEGSESAPEGQ-----AQQRRP-----YRRRRFPPYYMRRPYGR :::: . .. :: .. . : . : : ::: ::.::::::.. . . : XP_016 PRNYAGEEEEEGSGSSEGFDPPATDRQFSGARNQLRRPQYRPQYRQRRFPPYHVGQTFDR 190 200 210 220 230 240 210 220 230 240 250 pF1KB5 RPQYSNPP--VQ-GEVMEGADN--QGAGEQGRPVRQNMYRGYRPRFRRGPPRQRQPREDG : . : .: ::. : :. .:: :: ::..: ::: ::::: : : XP_016 RSRVLPHPNRIQAGEIGEMKDGVPEGAQLQG-PVHRNPT--YRP--SRGPPRPRPAPAVG 250 260 270 280 290 300 260 270 280 290 300 310 pF1KB5 NEEDKENQGDETQGQQPPQRR-YRRNFNYRRR-RPENPKPQDGKETKAADPPAENSSAPE . :::::: . .:: :: ::: .::::: :: : :::::.::.. :.:: :: XP_016 EAEDKENQQATSGPNQPSVRRGYRRPYNYRRRPRPPNAPSQDGKEAKAGEAPTENP-APP 310 320 330 340 350 360 320 pF1KB5 AEQGGAE ..:..:: XP_016 TQQSSAE >>NP_001138898 (OMIM: 603437) Y-box-binding protein 3 is (303 aa) initn: 903 init1: 614 opt: 769 Z-score: 561.6 bits: 112.1 E(85289): 1.5e-24 Smith-Waterman score: 915; 53.9% identity (65.3% similar) in 323 aa overlap (10-324:41-303) 10 20 30 pF1KB5 MSSEAETQQPPAAPPAAPALSAADTKPGTTGSGAGSGGP : :: :: :: .: . :: .. :..: NP_001 TTTTLPQAPTEAAAAAPQDPAPKSPVGSGAPQAAAPA-PAAHVAGN-PGGDAAPAATGTA 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 GGLTSAAPAGGD---KKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNP .. . :. ::.. :::.::::::::::::::::::::::::::::::::::::::::: NP_001 AAASLATAAGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNP 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 RKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSKYAADRNHYRR--YPRRRGP :::::::::::::::::::::::::::::::: ::::.::.::::: .::: : ::::: NP_001 RKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGP 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB5 PRNYQQNYQNSESGEKNEGSESAPEGQAQQRRPYRRRRFPPYYMRRPYGRRPQYSNPPVQ ::: .:: .: ....::: :: . : .: :: NP_001 PRN---------AGEIGEMKDGVPEG-AQLQGPVHR-------------------NPT-- 190 200 210 220 230 240 250 260 270 pF1KB5 GEVMEGADNQGAGEQGRPVRQNMYRGYRPRFR-RGPPRQRQPREDGNEEDKENQGDETQG ::::.: ::::: : :. :::::: . NP_001 --------------------------YRPRYRSRGPPRPRPAPAVGEAEDKENQQATSGP 220 230 240 250 280 290 300 310 320 pF1KB5 QQPPQRR-YRRNFNYRRR-RPENPKPQDGKETKAADPPAENSSAPEAEQGGAE .:: :: ::: .::::: :: : :::::.::.. :.:: :: ..:..:: NP_001 NQPSVRRGYRRPYNYRRRPRPPNAPSQDGKEAKAGEAPTENP-APPTQQSSAE 260 270 280 290 300 >>XP_016875612 (OMIM: 603437) PREDICTED: Y-box-binding p (300 aa) initn: 888 init1: 614 opt: 751 Z-score: 549.0 bits: 109.7 E(85289): 7.7e-24 Smith-Waterman score: 894; 53.4% identity (64.6% similar) in 322 aa overlap (10-324:41-300) 10 20 30 pF1KB5 MSSEAETQQPPAAPPAAPALSAADTKPGTTGSGAGSGGP : :: :: :: .: . :: .. :..: XP_016 TTTTLPQAPTEAAAAAPQDPAPKSPVGSGAPQAAAPA-PAAHVAGN-PGGDAAPAATGTA 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 GGLTSAAPAGGD---KKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNP .. . :. ::.. :::.::::::::::::::::::::::::::::::::::::::::: XP_016 AAASLATAAGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNP 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 RKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSKYAADRNHYRR--YPRRRGP :::::::::::::::::::::::::::::::: ::::.::.::::: .::: : ::::: XP_016 RKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGP 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB5 PRNYQQNYQNSESGEKNEGSESAPEGQAQQRRPYRRRRFPPYYMRRPYGRRPQYSNPPVQ ::: .:: .: ....::: :: . : .: :: XP_016 PRN---------AGEIGEMKDGVPEG-AQLQGPVHR-------------------NPT-- 190 200 210 220 230 240 250 260 270 pF1KB5 GEVMEGADNQGAGEQGRPVRQNMYRGYRPRFRRGPPRQRQPREDGNEEDKENQGDETQGQ ::: ::::: : :. :::::: . . XP_016 --------------------------YRP--SRGPPRPRPAPAVGEAEDKENQQATSGPN 220 230 240 280 290 300 310 320 pF1KB5 QPPQRR-YRRNFNYRRR-RPENPKPQDGKETKAADPPAENSSAPEAEQGGAE :: :: ::: .::::: :: : :::::.::.. :.:: :: ..:..:: XP_016 QPSVRRGYRRPYNYRRRPRPPNAPSQDGKEAKAGEAPTENP-APPTQQSSAE 250 260 270 280 290 300 >>XP_011519173 (OMIM: 603437) PREDICTED: Y-box-binding p (200 aa) initn: 669 init1: 614 opt: 706 Z-score: 519.3 bits: 103.7 E(85289): 3.5e-22 Smith-Waterman score: 706; 71.9% identity (83.8% similar) in 160 aa overlap (10-164:41-198) 10 20 30 pF1KB5 MSSEAETQQPPAAPPAAPALSAADTKPGTTGSGAGSGGP : :: :: :: .: . :: .. :..: XP_011 TTTTLPQAPTEAAAAAPQDPAPKSPVGSGAPQAAAPA-PAAHVAGN-PGGDAAPAATGTA 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 GGLTSAAPAGGD---KKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNP .. . :. ::.. :::.::::::::::::::::::::::::::::::::::::::::: XP_011 AAASLATAAGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNP 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 RKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSKYAADRNHYRR--YPRRRGP :::::::::::::::::::::::::::::::: ::::.::.::::: .::: : ::::: XP_011 RKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGP 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB5 PRNYQQNYQNSESGEKNEGSESAPEGQAQQRRPYRRRRFPPYYMRRPYGRRPQYSNPPVQ ::: .. . : XP_011 PRNISDVWFNRR 190 200 >>XP_016880202 (OMIM: 611447) PREDICTED: Y-box-binding p (379 aa) initn: 483 init1: 337 opt: 569 Z-score: 419.0 bits: 86.0 E(85289): 1.3e-16 Smith-Waterman score: 792; 46.0% identity (63.7% similar) in 339 aa overlap (10-316:53-367) 10 20 30 pF1KB5 MSSEAETQQPPAAPPAAPALSAADTKPGTTGSGAGSGGP : :. :.::. . ::. .. : :: : XP_016 AGVVAVVVPVPAGEPQKGGGAGGGGGAASGPAAGTPSAPG----SRTPGNPAT-AVSGTP 30 40 50 60 70 40 50 60 70 80 pF1KB5 GGLTSAAPA--GGDKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQ--------- : :: .:: :.: .:::::::::::::::::::::::::::::: XP_016 -----APPARSQADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVHQLENHCLVER 80 90 100 110 120 130 90 100 110 120 130 140 pF1KB5 ------TAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSKYAADR ::::.:::::.:::::::::::::::::::::::.::::::::::.::.:: .: XP_016 ALTGTETAIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEATNVTGPGGVPVKGSRYAPNR 140 150 160 170 180 190 150 160 170 180 190 pF1KB5 NHYRRY-PR--RRGPPRNYQQNYQNSESGEKNEGSESAPEGQAQQRRPYRRRRFPPYYMR . ::. :: .:: . .. .: ..: .. :: :: :: ::...: XP_016 RKSRRFIPRPPSVAPPPMVAE-IPSAGTGPGSKGERAEDSGQ----RP-RRWCPPPFFYR 200 210 220 230 240 200 210 220 230 240 pF1KB5 RPYGRRPQYSNPPVQGEVMEGADNQGAGEQGRPVRQNMYRG--------YRPRFRRG--P : . : :. :: : . .::.: : . :.. .. .: .:::.:: : XP_016 RRFVRGPR---PPNQQQPIEGTDRVEPKETA-PLEGHQQQGDERVPPPRFRPRYRRPFRP 250 260 270 280 290 300 250 260 270 280 290 300 pF1KB5 -PRQRQPREDGNEEDKENQGDETQGQQP-PQRRYRRNFNYRRRRPENPKPQDGKETKAAD :::. : :. : : .:: ..:..: ::: : . ..::: . : ::.. . . XP_016 RPRQQPTTEGGDGETKPSQGP-ADGSRPEPQRPRNRPY-FQRRRQQAPGPQQAPGPR--Q 310 320 330 340 350 310 320 pF1KB5 PPAENSSAPEAEQGGAE : : ..::: XP_016 PAAPETSAPVNSGDPTTTILE 360 370 >>XP_011534120 (OMIM: 611044) PREDICTED: protein lin-28 (258 aa) initn: 160 init1: 130 opt: 250 Z-score: 195.5 bits: 44.1 E(85289): 0.00037 Smith-Waterman score: 250; 26.9% identity (50.2% similar) in 271 aa overlap (19-275:3-256) 10 20 30 40 50 60 pF1KB5 MSSEAETQQPPAAPPAAPALSAADTKPGTTGSGAGSGGPGGLTSAAPAGGDKKVIATKVL ... ... :: ...:.: :: : :: ...:. . XP_011 MRSFNQVSSAPGGASKGGGEE-PGKLPE--PAEEESQVL--RGT 10 20 30 70 80 90 100 110 pF1KB5 GTVKWFNVRNGYGFI---NRN----DTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDV : :::::: :.::: ::. : ::::::. . .. .::. .:: ::: XP_011 GHCKWFNVRMGFGFISMINREGSPLDIPVDVFVHQSKLFMEG----FRSLKEGEPVEFTF 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB5 VEGEKGAEAANVTGPGGVPVQGS-KYAADRNHYRRYPRRRGPPRNYQQNYQNSESGEKNE .. :: :. :::::: : :: . .. .: :. : : :. . . .. : . XP_011 KKSSKGLESIRVTGPGGSPCLGSERRPKGKTLQKRKPK--GD-RCYNCGGLDHHAKECSL 100 110 120 130 140 150 180 190 200 210 220 pF1KB5 GSESAPEGQAQQ------RRPYRRRRFPPYYMRRPYGRRPQYSNPPVQGEVMEGADNQGA . :. :.. :: ::. :.: .. .. . : XP_011 PPQPKKCHYCQSIMHMVANCPHKNVAQPP---ASSQGRQEAESQPCTS--TLPREVGGGH 160 170 180 190 200 230 240 250 260 270 280 pF1KB5 GEQGRPVRQNMYRGYRPRFRRGPPRQRQPREDGNEEDKENQGDETQGQQPPQRRYRRNFN : . : :. : :.: . . . . :.. ..: .: .. XP_011 GCTSPPFPQEARAEISERSGRSPQEASSTKSSIAPEEQSKKGPSVQKRKKT 210 220 230 240 250 290 300 310 320 pF1KB5 YRRRRPENPKPQDGKETKAADPPAENSSAPEAEQGGAE >>XP_006715540 (OMIM: 611044) PREDICTED: protein lin-28 (269 aa) initn: 160 init1: 130 opt: 250 Z-score: 195.3 bits: 44.1 E(85289): 0.00039 Smith-Waterman score: 250; 26.9% identity (50.2% similar) in 271 aa overlap (19-275:14-267) 10 20 30 40 50 60 pF1KB5 MSSEAETQQPPAAPPAAPALSAADTKPGTTGSGAGSGGPGGLTSAAPAGGDKKVIATKVL ... ... :: ...:.: :: : :: ...:. . XP_006 MSHRRQVLQKRMRSFNQVSSAPGGASKGGGEE-PGKLPE--PAEEESQVL--RGT 10 20 30 40 50 70 80 90 100 110 pF1KB5 GTVKWFNVRNGYGFI---NRN----DTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDV : :::::: :.::: ::. : ::::::. . .. .::. .:: ::: XP_006 GHCKWFNVRMGFGFISMINREGSPLDIPVDVFVHQSKLFMEG----FRSLKEGEPVEFTF 60 70 80 90 100 120 130 140 150 160 170 pF1KB5 VEGEKGAEAANVTGPGGVPVQGS-KYAADRNHYRRYPRRRGPPRNYQQNYQNSESGEKNE .. :: :. :::::: : :: . .. .: :. : : :. . . .. : . XP_006 KKSSKGLESIRVTGPGGSPCLGSERRPKGKTLQKRKPK--GD-RCYNCGGLDHHAKECSL 110 120 130 140 150 160 180 190 200 210 220 pF1KB5 GSESAPEGQAQQ------RRPYRRRRFPPYYMRRPYGRRPQYSNPPVQGEVMEGADNQGA . :. :.. :: ::. :.: .. .. . : XP_006 PPQPKKCHYCQSIMHMVANCPHKNVAQPP---ASSQGRQEAESQPCTS--TLPREVGGGH 170 180 190 200 210 230 240 250 260 270 280 pF1KB5 GEQGRPVRQNMYRGYRPRFRRGPPRQRQPREDGNEEDKENQGDETQGQQPPQRRYRRNFN : . : :. : :.: . . . . :.. ..: .: .. XP_006 GCTSPPFPQEARAEISERSGRSPQEASSTKSSIAPEEQSKKGPSVQKRKKT 220 230 240 250 260 290 300 310 320 pF1KB5 YRRRRPENPKPQDGKETKAADPPAENSSAPEAEQGGAE 324 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 16:26:36 2016 done: Thu Nov 3 16:26:38 2016 Total Scan time: 9.270 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]