Result of FASTA (omim) for
pF1KB5263
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5263, 379 aa
1>>>pF1KB5263 379 - 379 aa - 379 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.8883+/-0.000627; mu= -27.6872+/- 0.037
mean_var=723.1821+/-164.945, 0's: 0 Z-trim(115.3): 1301 B-trim: 519 in 1/55
Lambda= 0.047693
statistics sampled from 23721 (25591) to 23721 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.3), width: 16
Scan time: 8.200
The best scores are: opt bits E(85289)
NP_002737 (OMIM: 601795) mitogen-activated protein ( 379) 2542 190.8 4.4e-48
NP_001035145 (OMIM: 601795) mitogen-activated prot ( 357) 2281 172.8 1.1e-42
NP_002736 (OMIM: 176948) mitogen-activated protein ( 360) 2109 161.0 3.9e-39
NP_620407 (OMIM: 176948) mitogen-activated protein ( 360) 2109 161.0 3.9e-39
NP_001103361 (OMIM: 601795) mitogen-activated prot ( 335) 1741 135.7 1.6e-31
NP_620603 (OMIM: 602521) mitogen-activated protein ( 816) 1158 96.0 3.4e-19
NP_620602 (OMIM: 602521) mitogen-activated protein ( 816) 1158 96.0 3.4e-19
NP_002740 (OMIM: 602521) mitogen-activated protein ( 816) 1158 96.0 3.4e-19
NP_620581 (OMIM: 600289) mitogen-activated protein ( 360) 1084 90.5 6.7e-18
NP_001306 (OMIM: 600289) mitogen-activated protein ( 360) 1071 89.6 1.2e-17
NP_002742 (OMIM: 602898) mitogen-activated protein ( 364) 1065 89.2 1.7e-17
XP_011512612 (OMIM: 600289) PREDICTED: mitogen-act ( 401) 1026 86.6 1.1e-16
NP_002745 (OMIM: 602899) mitogen-activated protein ( 365) 1005 85.1 2.9e-16
NP_002960 (OMIM: 602399) mitogen-activated protein ( 367) 955 81.6 3.2e-15
XP_006715061 (OMIM: 600289) PREDICTED: mitogen-act ( 283) 935 80.1 6.9e-15
XP_006721622 (OMIM: 602521) PREDICTED: mitogen-act ( 822) 934 80.6 1.5e-14
XP_006721621 (OMIM: 602521) PREDICTED: mitogen-act ( 822) 934 80.6 1.5e-14
XP_006721620 (OMIM: 602521) PREDICTED: mitogen-act ( 822) 934 80.6 1.5e-14
XP_011522259 (OMIM: 602521) PREDICTED: mitogen-act ( 677) 906 78.6 4.9e-14
NP_620601 (OMIM: 602521) mitogen-activated protein ( 677) 906 78.6 4.9e-14
XP_011524378 (OMIM: 176949) PREDICTED: mitogen-act ( 587) 894 77.7 8e-14
XP_016881328 (OMIM: 176949) PREDICTED: mitogen-act ( 587) 894 77.7 8e-14
XP_005258356 (OMIM: 176949) PREDICTED: mitogen-act ( 587) 894 77.7 8e-14
XP_011524377 (OMIM: 176949) PREDICTED: mitogen-act ( 587) 894 77.7 8e-14
NP_002738 (OMIM: 176949) mitogen-activated protein ( 587) 894 77.7 8e-14
XP_011524376 (OMIM: 176949) PREDICTED: mitogen-act ( 587) 894 77.7 8e-14
NP_620708 (OMIM: 602896) mitogen-activated protein ( 382) 887 77.0 8.4e-14
NP_620709 (OMIM: 602896) mitogen-activated protein ( 424) 887 77.0 9e-14
XP_016865127 (OMIM: 602896) PREDICTED: mitogen-act ( 424) 887 77.0 9e-14
XP_016863924 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 884 76.8 9.7e-14
XP_016863923 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 884 76.8 9.7e-14
XP_016863927 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 884 76.8 9.7e-14
XP_016863928 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 884 76.8 9.7e-14
XP_016863925 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 884 76.8 9.7e-14
XP_016863926 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 884 76.8 9.7e-14
NP_620582 (OMIM: 600289) mitogen-activated protein ( 297) 880 76.4 9.9e-14
XP_016865790 (OMIM: 600289) PREDICTED: mitogen-act ( 301) 880 76.4 1e-13
XP_005263192 (OMIM: 602897) PREDICTED: mitogen-act ( 422) 884 76.8 1e-13
XP_016863918 (OMIM: 602897) PREDICTED: mitogen-act ( 422) 884 76.8 1e-13
XP_016863920 (OMIM: 602897) PREDICTED: mitogen-act ( 422) 884 76.8 1e-13
XP_016863919 (OMIM: 602897) PREDICTED: mitogen-act ( 422) 884 76.8 1e-13
NP_002744 (OMIM: 602897) mitogen-activated protein ( 422) 884 76.8 1e-13
XP_016863921 (OMIM: 602897) PREDICTED: mitogen-act ( 422) 884 76.8 1e-13
XP_011530423 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 884 76.8 1e-13
XP_016863912 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 884 76.8 1e-13
XP_016863914 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 884 76.8 1e-13
XP_016863915 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 884 76.8 1e-13
XP_016863913 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 884 76.8 1e-13
XP_006714331 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 884 76.8 1e-13
XP_011530422 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 884 76.8 1e-13
>>NP_002737 (OMIM: 601795) mitogen-activated protein kin (379 aa)
initn: 2542 init1: 2542 opt: 2542 Z-score: 984.3 bits: 190.8 E(85289): 4.4e-48
Smith-Waterman score: 2542; 100.0% identity (100.0% similar) in 379 aa overlap (1-379:1-379)
10 20 30 40 50 60
pF1KB5 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERL
310 320 330 340 350 360
370
pF1KB5 KELIFQETARFQPGVLEAP
:::::::::::::::::::
NP_002 KELIFQETARFQPGVLEAP
370
>>NP_001035145 (OMIM: 601795) mitogen-activated protein (357 aa)
initn: 2277 init1: 2277 opt: 2281 Z-score: 887.5 bits: 172.8 E(85289): 1.1e-42
Smith-Waterman score: 2281; 98.8% identity (99.4% similar) in 345 aa overlap (1-345:1-344)
10 20 30 40 50 60
pF1KB5 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERL
::::::::::::::::::::::::::::::::::::::: :.. :
NP_001 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDE-VGQSPAAVGLGAGEQGGT
310 320 330 340 350
370
pF1KB5 KELIFQETARFQPGVLEAP
>>NP_002736 (OMIM: 176948) mitogen-activated protein kin (360 aa)
initn: 2138 init1: 2105 opt: 2109 Z-score: 823.5 bits: 161.0 E(85289): 3.9e-39
Smith-Waterman score: 2109; 86.5% identity (94.4% similar) in 356 aa overlap (19-374:8-357)
10 20 30 40 50 60
pF1KB5 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
:.:: :::.:: ::::::::.:.:::::::::: :::
NP_002 MAAAAAAGAGP------EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAY
10 20 30 40
70 80 90 100 110 120
pF1KB5 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
:.: :.:::::::::::::::::::::::.:::::::::.::: ::.:: :.: :.::::
NP_002 DNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYI
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
::::::::::::::.:.::::::::::::::::::::::::::::::::::::.::::::
NP_002 VQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB5 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
:::::::::.:::.::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB5 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
::::::::::::::::::::::::::::::::::.:::::: ::: :.:: : .:::..:
NP_002 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNAD
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERL
::::::::.::::::.::: ::.:::::::::::::.:::.:: :: : :::::::::.:
NP_002 SKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKL
290 300 310 320 330 340
370
pF1KB5 KELIFQETARFQPGVLEAP
:::::.::::::::
NP_002 KELIFEETARFQPGYRS
350 360
>>NP_620407 (OMIM: 176948) mitogen-activated protein kin (360 aa)
initn: 2138 init1: 2105 opt: 2109 Z-score: 823.5 bits: 161.0 E(85289): 3.9e-39
Smith-Waterman score: 2109; 86.5% identity (94.4% similar) in 356 aa overlap (19-374:8-357)
10 20 30 40 50 60
pF1KB5 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
:.:: :::.:: ::::::::.:.:::::::::: :::
NP_620 MAAAAAAGAGP------EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAY
10 20 30 40
70 80 90 100 110 120
pF1KB5 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
:.: :.:::::::::::::::::::::::.:::::::::.::: ::.:: :.: :.::::
NP_620 DNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYI
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
::::::::::::::.:.::::::::::::::::::::::::::::::::::::.::::::
NP_620 VQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB5 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
:::::::::.:::.::::::::::::::::::::::::::::::::::::::::::::::
NP_620 KICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB5 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
::::::::::::::::::::::::::::::::::.:::::: ::: :.:: : .:::..:
NP_620 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNAD
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERL
::::::::.::::::.::: ::.:::::::::::::.:::.:: :: : :::::::::.:
NP_620 SKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKL
290 300 310 320 330 340
370
pF1KB5 KELIFQETARFQPGVLEAP
:::::.::::::::
NP_620 KELIFEETARFQPGYRS
350 360
>>NP_001103361 (OMIM: 601795) mitogen-activated protein (335 aa)
initn: 1776 init1: 1741 opt: 1741 Z-score: 687.1 bits: 135.7 E(85289): 1.6e-31
Smith-Waterman score: 2152; 88.4% identity (88.4% similar) in 379 aa overlap (1-379:1-335)
10 20 30 40 50 60
pF1KB5 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
::::::::::::::::::
NP_001 NRPIFPGKHYLDQLNHIL------------------------------------------
250
310 320 330 340 350 360
pF1KB5 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --ALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERL
260 270 280 290 300 310
370
pF1KB5 KELIFQETARFQPGVLEAP
:::::::::::::::::::
NP_001 KELIFQETARFQPGVLEAP
320 330
>>NP_620603 (OMIM: 602521) mitogen-activated protein kin (816 aa)
initn: 1074 init1: 601 opt: 1158 Z-score: 465.7 bits: 96.0 E(85289): 3.4e-19
Smith-Waterman score: 1158; 51.0% identity (76.5% similar) in 341 aa overlap (36-372:49-389)
10 20 30 40 50 60
pF1KB5 AQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRK
:::: .: .. ::.::::.:::: ..
NP_620 GPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTG
20 30 40 50 60 70
70 80 90 100 110 120
pF1KB5 TRVAIKKI-SPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAST-LEAMRDVYIVQD
.:::::: . :. : .:::::..:: .:.:.:.:.:.:::: .. ...::.: :
NP_620 QQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLD
80 90 100 110 120 130
130 140 150 160 170 180
pF1KB5 LMETDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKI
:::.::.....:.: :. .:. :::::.::::::.:::.:.::::::::::.: .:.:::
NP_620 LMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKI
140 150 160 170 180 190
190 200 210 220 230 240
pF1KB5 CDFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN
:::.:: . .: :.:::::::::::::.::. . ::..::.::::::..:::.
NP_620 GDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR
200 210 220 230 240 250
250 260 270 280 290 300
pF1KB5 RPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDS
: .::::.:. ::. :. .::.:: .. . ..: :.:::: . : : ..: .:
NP_620 RQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADR
260 270 280 290 300 310
310 320 330 340 350 360
pF1KB5 KALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLK
.::.:: ::: :.:. ::.. :: ::.: .:.:: ::: :: ::.. . : .::.:
NP_620 QALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIK
320 330 340 350 360 370
370
pF1KB5 ELIFQETARFQPGVLEAP
: : : :.
NP_620 EAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAP
380 390 400 410 420 430
>>NP_620602 (OMIM: 602521) mitogen-activated protein kin (816 aa)
initn: 1074 init1: 601 opt: 1158 Z-score: 465.7 bits: 96.0 E(85289): 3.4e-19
Smith-Waterman score: 1158; 51.0% identity (76.5% similar) in 341 aa overlap (36-372:49-389)
10 20 30 40 50 60
pF1KB5 AQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRK
:::: .: .. ::.::::.:::: ..
NP_620 GPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTG
20 30 40 50 60 70
70 80 90 100 110 120
pF1KB5 TRVAIKKI-SPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAST-LEAMRDVYIVQD
.:::::: . :. : .:::::..:: .:.:.:.:.:.:::: .. ...::.: :
NP_620 QQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLD
80 90 100 110 120 130
130 140 150 160 170 180
pF1KB5 LMETDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKI
:::.::.....:.: :. .:. :::::.::::::.:::.:.::::::::::.: .:.:::
NP_620 LMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKI
140 150 160 170 180 190
190 200 210 220 230 240
pF1KB5 CDFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN
:::.:: . .: :.:::::::::::::.::. . ::..::.::::::..:::.
NP_620 GDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR
200 210 220 230 240 250
250 260 270 280 290 300
pF1KB5 RPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDS
: .::::.:. ::. :. .::.:: .. . ..: :.:::: . : : ..: .:
NP_620 RQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADR
260 270 280 290 300 310
310 320 330 340 350 360
pF1KB5 KALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLK
.::.:: ::: :.:. ::.. :: ::.: .:.:: ::: :: ::.. . : .::.:
NP_620 QALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIK
320 330 340 350 360 370
370
pF1KB5 ELIFQETARFQPGVLEAP
: : : :.
NP_620 EAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAP
380 390 400 410 420 430
>>NP_002740 (OMIM: 602521) mitogen-activated protein kin (816 aa)
initn: 1074 init1: 601 opt: 1158 Z-score: 465.7 bits: 96.0 E(85289): 3.4e-19
Smith-Waterman score: 1158; 51.0% identity (76.5% similar) in 341 aa overlap (36-372:49-389)
10 20 30 40 50 60
pF1KB5 AQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRK
:::: .: .. ::.::::.:::: ..
NP_002 GPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTG
20 30 40 50 60 70
70 80 90 100 110 120
pF1KB5 TRVAIKKI-SPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAST-LEAMRDVYIVQD
.:::::: . :. : .:::::..:: .:.:.:.:.:.:::: .. ...::.: :
NP_002 QQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLD
80 90 100 110 120 130
130 140 150 160 170 180
pF1KB5 LMETDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKI
:::.::.....:.: :. .:. :::::.::::::.:::.:.::::::::::.: .:.:::
NP_002 LMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKI
140 150 160 170 180 190
190 200 210 220 230 240
pF1KB5 CDFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN
:::.:: . .: :.:::::::::::::.::. . ::..::.::::::..:::.
NP_002 GDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR
200 210 220 230 240 250
250 260 270 280 290 300
pF1KB5 RPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDS
: .::::.:. ::. :. .::.:: .. . ..: :.:::: . : : ..: .:
NP_002 RQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADR
260 270 280 290 300 310
310 320 330 340 350 360
pF1KB5 KALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLK
.::.:: ::: :.:. ::.. :: ::.: .:.:: ::: :: ::.. . : .::.:
NP_002 QALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIK
320 330 340 350 360 370
370
pF1KB5 ELIFQETARFQPGVLEAP
: : : :.
NP_002 EAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAP
380 390 400 410 420 430
>>NP_620581 (OMIM: 600289) mitogen-activated protein kin (360 aa)
initn: 1045 init1: 516 opt: 1084 Z-score: 442.4 bits: 90.5 E(85289): 6.7e-18
Smith-Waterman score: 1084; 49.1% identity (75.3% similar) in 344 aa overlap (36-377:18-354)
10 20 30 40 50 60
pF1KB5 AQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRK
..: :: .:. .: :::: : .:.:
NP_620 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTG
10 20 30 40
70 80 90 100 110 120
pF1KB5 TRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHENVIGIRDILR-ASTLEAMRDVYIVQD
:::.::.: ::. . .:: ::...: ...::::::. :.. : .:: . :::.:
NP_620 LRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTH
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 LMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKIC
:: .:: ...: :.:..::. ...:::::::::::::...::::::::: .: :.:::
NP_620 LMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKIL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB5 DFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRP
:::::: .: : .: ::::::::::::::: :....::::::::.::.:..:
NP_620 DFGLARHTDDE------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRT
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB5 IFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKA
.::: ..:::. :: ..:.:. : :. : . .::::.::: . :. .:..: .. :
NP_620 LFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLA
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 LDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLKEL
.:::..::... .::::. .:::: :. ::.:: :::::. :. ..: :: .. : :
NP_620 VDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVAD-PYDQSFESRDLLIDEWKSL
290 300 310 320 330 340
370
pF1KB5 IFQETARFQPGVLEAP
..:. : : :.
NP_620 TYDEVISFVPPPLDQEEMES
350 360
>>NP_001306 (OMIM: 600289) mitogen-activated protein kin (360 aa)
initn: 1032 init1: 503 opt: 1071 Z-score: 437.5 bits: 89.6 E(85289): 1.2e-17
Smith-Waterman score: 1071; 48.0% identity (74.7% similar) in 344 aa overlap (36-377:18-354)
10 20 30 40 50 60
pF1KB5 AQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRK
..: :: .:. .: :::: : .:.:
NP_001 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTG
10 20 30 40
70 80 90 100 110 120
pF1KB5 TRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHENVIGIRDILR-ASTLEAMRDVYIVQD
:::.::.: ::. . .:: ::...: ...::::::. :.. : .:: . :::.:
NP_001 LRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTH
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 LMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKIC
:: .:: ...: :.:..::. ...:::::::::::::...::::::::: .: :.:::
NP_001 LMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKIL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB5 DFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRP
:::::: .: : .: ::::::::::::::: :....::::::::.::.:..:
NP_001 DFGLARHTDDE------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRT
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB5 IFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKA
.::: ...::..:. . :.: .: . . .::::.::: . :. .:..: .. :
NP_001 LFPGTDHINQLQQIMRLTGTPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLA
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 LDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLKEL
.:::..::... .::::. .:::: :. ::.:: :::::. :. ..: :: .. : :
NP_001 VDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVAD-PYDQSFESRDLLIDEWKSL
290 300 310 320 330 340
370
pF1KB5 IFQETARFQPGVLEAP
..:. : : :.
NP_001 TYDEVISFVPPPLDQEEMES
350 360
379 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 16:28:01 2016 done: Thu Nov 3 16:28:02 2016
Total Scan time: 8.200 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]