FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5264, 312 aa 1>>>pF1KB5264 312 - 312 aa - 312 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3455+/-0.00044; mu= 15.7114+/- 0.027 mean_var=69.9550+/-14.411, 0's: 0 Z-trim(109.8): 134 B-trim: 0 in 0/50 Lambda= 0.153343 statistics sampled from 17935 (18072) to 17935 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.561), E-opt: 0.2 (0.212), width: 16 Scan time: 6.050 The best scores are: opt bits E(85289) NP_057226 (OMIM: 609574) very-long-chain 3-oxoacyl ( 312) 1995 450.7 1.7e-126 XP_016873370 (OMIM: 609574) PREDICTED: very-long-c ( 280) 1632 370.4 2.4e-102 XP_011518458 (OMIM: 609574) PREDICTED: very-long-c ( 238) 1505 342.3 5.9e-94 XP_011516920 (OMIM: 264300,605573) PREDICTED: test ( 310) 707 165.8 1e-40 XP_016870160 (OMIM: 264300,605573) PREDICTED: test ( 310) 707 165.8 1e-40 NP_000188 (OMIM: 264300,605573) testosterone 17-be ( 310) 707 165.8 1e-40 XP_011516921 (OMIM: 264300,605573) PREDICTED: test ( 310) 707 165.8 1e-40 XP_016870161 (OMIM: 264300,605573) PREDICTED: test ( 310) 707 165.8 1e-40 XP_016870165 (OMIM: 264300,605573) PREDICTED: test ( 238) 599 141.8 1.3e-33 XP_016870164 (OMIM: 264300,605573) PREDICTED: test ( 256) 513 122.8 7.3e-28 XP_016870163 (OMIM: 264300,605573) PREDICTED: test ( 274) 408 99.6 7.6e-21 XP_016870162 (OMIM: 264300,605573) PREDICTED: test ( 298) 365 90.1 5.9e-18 XP_016870166 (OMIM: 264300,605573) PREDICTED: test ( 190) 359 88.7 1e-17 NP_057329 (OMIM: 612831) estradiol 17-beta-dehydro ( 300) 270 69.1 1.3e-11 NP_001317088 (OMIM: 616160) dehydrogenase/reductas ( 310) 270 69.1 1.3e-11 NP_056325 (OMIM: 616160) dehydrogenase/reductase S ( 325) 270 69.1 1.4e-11 XP_016879915 (OMIM: 616160) PREDICTED: dehydrogena ( 325) 270 69.1 1.4e-11 XP_011522088 (OMIM: 616160) PREDICTED: dehydrogena ( 334) 270 69.1 1.4e-11 NP_001309209 (OMIM: 612833) dehydrogenase/reductas ( 289) 269 68.9 1.4e-11 XP_005256652 (OMIM: 616160) PREDICTED: dehydrogena ( 372) 270 69.2 1.5e-11 XP_016879914 (OMIM: 616160) PREDICTED: dehydrogena ( 372) 270 69.2 1.5e-11 NP_057113 (OMIM: 612833) dehydrogenase/reductase S ( 339) 269 68.9 1.6e-11 XP_016876857 (OMIM: 612833) PREDICTED: dehydrogena ( 404) 269 69.0 1.9e-11 NP_066284 (OMIM: 611596) dehydrogenase/reductase S ( 278) 253 65.3 1.6e-10 NP_077284 (OMIM: 616159) dehydrogenase/reductase S ( 260) 248 64.2 3.3e-10 NP_001193670 (OMIM: 600713,614662) corticosteroid ( 292) 248 64.2 3.6e-10 NP_005516 (OMIM: 600713,614662) corticosteroid 11- ( 292) 248 64.2 3.6e-10 NP_861420 (OMIM: 600713,614662) corticosteroid 11- ( 292) 248 64.2 3.6e-10 NP_835236 (OMIM: 612127) 17-beta-hydroxysteroid de ( 300) 246 63.8 5e-10 XP_016862499 (OMIM: 603063) PREDICTED: D-beta-hydr ( 324) 243 63.1 8.5e-10 XP_016862498 (OMIM: 603063) PREDICTED: D-beta-hydr ( 324) 243 63.1 8.5e-10 XP_016862501 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330) 243 63.1 8.6e-10 XP_016862497 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330) 243 63.1 8.6e-10 XP_016862500 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330) 243 63.1 8.6e-10 XP_005269409 (OMIM: 603063) PREDICTED: D-beta-hydr ( 343) 243 63.2 8.9e-10 NP_004042 (OMIM: 603063) D-beta-hydroxybutyrate de ( 343) 243 63.2 8.9e-10 NP_976059 (OMIM: 603063) D-beta-hydroxybutyrate de ( 343) 243 63.2 8.9e-10 NP_976060 (OMIM: 603063) D-beta-hydroxybutyrate de ( 343) 243 63.2 8.9e-10 XP_016862496 (OMIM: 603063) PREDICTED: D-beta-hydr ( 343) 243 63.2 8.9e-10 XP_011511369 (OMIM: 603063) PREDICTED: D-beta-hydr ( 347) 243 63.2 9e-10 NP_002026 (OMIM: 136440) 3-ketodihydrosphingosine ( 332) 240 62.5 1.4e-09 XP_005257715 (OMIM: 616159) PREDICTED: dehydrogena ( 229) 238 61.9 1.4e-09 XP_005266734 (OMIM: 136440) PREDICTED: 3-ketodihyd ( 298) 237 61.8 2e-09 NP_004744 (OMIM: 612830) short-chain dehydrogenase ( 302) 236 61.6 2.3e-09 NP_056540 (OMIM: 608575) retinol dehydrogenase 8 [ ( 331) 229 60.1 7.4e-09 NP_620419 (OMIM: 608989) epidermal retinol dehydro ( 309) 225 59.1 1.3e-08 XP_006720064 (OMIM: 615194) PREDICTED: dehydrogena ( 280) 224 58.9 1.4e-08 XP_005267306 (OMIM: 615194) PREDICTED: dehydrogena ( 280) 224 58.9 1.4e-08 NP_005785 (OMIM: 615194) dehydrogenase/reductase S ( 280) 224 58.9 1.4e-08 NP_878912 (OMIM: 615194) dehydrogenase/reductase S ( 300) 224 58.9 1.5e-08 >>NP_057226 (OMIM: 609574) very-long-chain 3-oxoacyl-CoA (312 aa) initn: 1995 init1: 1995 opt: 1995 Z-score: 2391.9 bits: 450.7 E(85289): 1.7e-126 Smith-Waterman score: 1995; 100.0% identity (100.0% similar) in 312 aa overlap (1-312:1-312) 10 20 30 40 50 60 pF1KB5 MESALPAAGFLYWVGAGTVAYLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MESALPAAGFLYWVGAGTVAYLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 GIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 GLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 KGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 KIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNKS 250 260 270 280 290 300 310 pF1KB5 TRAHYLKKTKKN :::::::::::: NP_057 TRAHYLKKTKKN 310 >>XP_016873370 (OMIM: 609574) PREDICTED: very-long-chain (280 aa) initn: 1632 init1: 1632 opt: 1632 Z-score: 1958.5 bits: 370.4 E(85289): 2.4e-102 Smith-Waterman score: 1632; 100.0% identity (100.0% similar) in 258 aa overlap (55-312:23-280) 30 40 50 60 70 80 pF1KB5 RISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSK :::::::::::::::::::::::::::::: XP_016 MEPVSRPAASSVTRCPPWFAPFVTGSTDGIGKSYAEELAKHGMKVVLISRSK 10 20 30 40 50 90 100 110 120 130 140 pF1KB5 DKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYF 60 70 80 90 100 110 150 160 170 180 190 200 pF1KB5 LDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSA 120 130 140 150 160 170 210 220 230 240 250 260 pF1KB5 TKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVG 180 190 200 210 220 230 270 280 290 300 310 pF1KB5 LQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNKSTRAHYLKKTKKN :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNKSTRAHYLKKTKKN 240 250 260 270 280 >>XP_011518458 (OMIM: 609574) PREDICTED: very-long-chain (238 aa) initn: 1505 init1: 1505 opt: 1505 Z-score: 1807.7 bits: 342.3 E(85289): 5.9e-94 Smith-Waterman score: 1505; 100.0% identity (100.0% similar) in 238 aa overlap (75-312:1-238) 50 60 70 80 90 100 pF1KB5 VGPGLGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRT :::::::::::::::::::::::::::::: XP_011 MKVVLISRSKDKLDQVSSEIKEKFKVETRT 10 20 30 110 120 130 140 150 160 pF1KB5 IAVDFASEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAVDFASEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILS 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB5 VCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKG 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB5 VFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISN 160 170 180 190 200 210 290 300 310 pF1KB5 LPSWIYLKIVMNMNKSTRAHYLKKTKKN :::::::::::::::::::::::::::: XP_011 LPSWIYLKIVMNMNKSTRAHYLKKTKKN 220 230 >>XP_011516920 (OMIM: 264300,605573) PREDICTED: testoste (310 aa) initn: 691 init1: 345 opt: 707 Z-score: 851.9 bits: 165.8 E(85289): 1e-40 Smith-Waterman score: 707; 41.7% identity (71.2% similar) in 295 aa overlap (19-312:18-306) 10 20 30 40 50 60 pF1KB5 MESALPAAGFLYWVGAGTVAYLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTD .: :: . .: . : : : .. . ..:.:::.::. : XP_011 MGDVLEQFFILTGLLVCLACLAKCVRFSRCVLLNYWKVLPKSFLR-SMGQWAVITGAGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 GIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKT ::::.:. ::::.:..::::::. .::. ...::.. .. : .::...:::..:: XP_011 GIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKE 60 70 80 90 100 110 130 140 150 160 170 pF1KB5 GLAGLEIGILVNNVGMSYEY-PEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVER ::::::::::::::: . : .::..:: :...:. :: :: :::::.: : : XP_011 KLAGLEIGILVNNVGMLPNLLPSHFLNAPDE---IQSLIHCNITSVVKMTQLILKHMESR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 SKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKL .:: ::::::: ...: :: ..:::.:.:: ::. :.:::..: :..: . :: :.: . XP_011 QKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 AKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNK .: . .. . . ::: ... : . ..: : : : ......: .:.: . . .. .. XP_011 TKYLNTNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAF--QR 240 250 260 270 280 290 300 310 pF1KB5 STRAHYLKKTKKN .::. : : XP_011 LLLTHYVAYLKLNTKVR 300 310 >>XP_016870160 (OMIM: 264300,605573) PREDICTED: testoste (310 aa) initn: 691 init1: 345 opt: 707 Z-score: 851.9 bits: 165.8 E(85289): 1e-40 Smith-Waterman score: 707; 41.7% identity (71.2% similar) in 295 aa overlap (19-312:18-306) 10 20 30 40 50 60 pF1KB5 MESALPAAGFLYWVGAGTVAYLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTD .: :: . .: . : : : .. . ..:.:::.::. : XP_016 MGDVLEQFFILTGLLVCLACLAKCVRFSRCVLLNYWKVLPKSFLR-SMGQWAVITGAGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 GIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKT ::::.:. ::::.:..::::::. .::. ...::.. .. : .::...:::..:: XP_016 GIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKE 60 70 80 90 100 110 130 140 150 160 170 pF1KB5 GLAGLEIGILVNNVGMSYEY-PEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVER ::::::::::::::: . : .::..:: :...:. :: :: :::::.: : : XP_016 KLAGLEIGILVNNVGMLPNLLPSHFLNAPDE---IQSLIHCNITSVVKMTQLILKHMESR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 SKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKL .:: ::::::: ...: :: ..:::.:.:: ::. :.:::..: :..: . :: :.: . XP_016 QKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 AKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNK .: . .. . . ::: ... : . ..: : : : ......: .:.: . . .. .. XP_016 TKYLNTNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAF--QR 240 250 260 270 280 290 300 310 pF1KB5 STRAHYLKKTKKN .::. : : XP_016 LLLTHYVAYLKLNTKVR 300 310 >>NP_000188 (OMIM: 264300,605573) testosterone 17-beta-d (310 aa) initn: 691 init1: 345 opt: 707 Z-score: 851.9 bits: 165.8 E(85289): 1e-40 Smith-Waterman score: 707; 41.7% identity (71.2% similar) in 295 aa overlap (19-312:18-306) 10 20 30 40 50 60 pF1KB5 MESALPAAGFLYWVGAGTVAYLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTD .: :: . .: . : : : .. . ..:.:::.::. : NP_000 MGDVLEQFFILTGLLVCLACLAKCVRFSRCVLLNYWKVLPKSFLR-SMGQWAVITGAGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 GIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKT ::::.:. ::::.:..::::::. .::. ...::.. .. : .::...:::..:: NP_000 GIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKE 60 70 80 90 100 110 130 140 150 160 170 pF1KB5 GLAGLEIGILVNNVGMSYEY-PEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVER ::::::::::::::: . : .::..:: :...:. :: :: :::::.: : : NP_000 KLAGLEIGILVNNVGMLPNLLPSHFLNAPDE---IQSLIHCNITSVVKMTQLILKHMESR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 SKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKL .:: ::::::: ...: :: ..:::.:.:: ::. :.:::..: :..: . :: :.: . NP_000 QKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 AKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNK .: . .. . . ::: ... : . ..: : : : ......: .:.: . . .. .. NP_000 TKYLNTNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAF--QR 240 250 260 270 280 290 300 310 pF1KB5 STRAHYLKKTKKN .::. : : NP_000 LLLTHYVAYLKLNTKVR 300 310 >>XP_011516921 (OMIM: 264300,605573) PREDICTED: testoste (310 aa) initn: 691 init1: 345 opt: 707 Z-score: 851.9 bits: 165.8 E(85289): 1e-40 Smith-Waterman score: 707; 41.7% identity (71.2% similar) in 295 aa overlap (19-312:18-306) 10 20 30 40 50 60 pF1KB5 MESALPAAGFLYWVGAGTVAYLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTD .: :: . .: . : : : .. . ..:.:::.::. : XP_011 MGDVLEQFFILTGLLVCLACLAKCVRFSRCVLLNYWKVLPKSFLR-SMGQWAVITGAGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 GIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKT ::::.:. ::::.:..::::::. .::. ...::.. .. : .::...:::..:: XP_011 GIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKE 60 70 80 90 100 110 130 140 150 160 170 pF1KB5 GLAGLEIGILVNNVGMSYEY-PEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVER ::::::::::::::: . : .::..:: :...:. :: :: :::::.: : : XP_011 KLAGLEIGILVNNVGMLPNLLPSHFLNAPDE---IQSLIHCNITSVVKMTQLILKHMESR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 SKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKL .:: ::::::: ...: :: ..:::.:.:: ::. :.:::..: :..: . :: :.: . XP_011 QKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 AKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNK .: . .. . . ::: ... : . ..: : : : ......: .:.: . . .. .. XP_011 TKYLNTNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAF--QR 240 250 260 270 280 290 300 310 pF1KB5 STRAHYLKKTKKN .::. : : XP_011 LLLTHYVAYLKLNTKVR 300 310 >>XP_016870161 (OMIM: 264300,605573) PREDICTED: testoste (310 aa) initn: 691 init1: 345 opt: 707 Z-score: 851.9 bits: 165.8 E(85289): 1e-40 Smith-Waterman score: 707; 41.7% identity (71.2% similar) in 295 aa overlap (19-312:18-306) 10 20 30 40 50 60 pF1KB5 MESALPAAGFLYWVGAGTVAYLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTD .: :: . .: . : : : .. . ..:.:::.::. : XP_016 MGDVLEQFFILTGLLVCLACLAKCVRFSRCVLLNYWKVLPKSFLR-SMGQWAVITGAGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 GIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKT ::::.:. ::::.:..::::::. .::. ...::.. .. : .::...:::..:: XP_016 GIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKE 60 70 80 90 100 110 130 140 150 160 170 pF1KB5 GLAGLEIGILVNNVGMSYEY-PEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVER ::::::::::::::: . : .::..:: :...:. :: :: :::::.: : : XP_016 KLAGLEIGILVNNVGMLPNLLPSHFLNAPDE---IQSLIHCNITSVVKMTQLILKHMESR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 SKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKL .:: ::::::: ...: :: ..:::.:.:: ::. :.:::..: :..: . :: :.: . XP_016 QKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 AKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNK .: . .. . . ::: ... : . ..: : : : ......: .:.: . . .. .. XP_016 TKYLNTNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAF--QR 240 250 260 270 280 290 300 310 pF1KB5 STRAHYLKKTKKN .::. : : XP_016 LLLTHYVAYLKLNTKVR 300 310 >>XP_016870165 (OMIM: 264300,605573) PREDICTED: testoste (238 aa) initn: 585 init1: 330 opt: 599 Z-score: 724.5 bits: 141.8 E(85289): 1.3e-33 Smith-Waterman score: 599; 48.8% identity (75.4% similar) in 211 aa overlap (19-228:18-224) 10 20 30 40 50 60 pF1KB5 MESALPAAGFLYWVGAGTVAYLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTD .: :: . .: . : : : .. . ..:.:::.::. : XP_016 MGDVLEQFFILTGLLVCLACLAKCVRFSRCVLLNYWKVLPKSFLR-SMGQWAVITGAGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 GIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKT ::::.:. ::::.:..::::::. .::. ...::.. .. : .::...:::..:: XP_016 GIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKE 60 70 80 90 100 110 130 140 150 160 170 pF1KB5 GLAGLEIGILVNNVGMSYEY-PEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVER ::::::::::::::: . : .::..:: :...:. :: :: :::::.: : : XP_016 KLAGLEIGILVNNVGMLPNLLPSHFLNAPD---EIQSLIHCNITSVVKMTQLILKHMESR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 SKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKL .:: ::::::: ...: :: ..:::.:.:: ::. :.:::..: :..: XP_016 QKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVRWAAVESLSS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 AKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNK XP_016 SRC >>XP_016870164 (OMIM: 264300,605573) PREDICTED: testoste (256 aa) initn: 507 init1: 345 opt: 513 Z-score: 621.2 bits: 122.8 E(85289): 7.3e-28 Smith-Waterman score: 513; 42.2% identity (71.1% similar) in 211 aa overlap (103-312:47-252) 80 90 100 110 120 130 pF1KB5 HGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKTGLAGLEIGILVN . : .::...:::..:: ::::::::::: XP_016 VNGTVGSDHWSRRWNWESVLVRERTTGRSVKIIQADFTKDDIYEHIKEKLAGLEIGILVN 20 30 40 50 60 70 140 150 160 170 180 190 pF1KB5 NVGMSYEY-PEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGS :::: . : .::..:: :...:. :: :: :::::.: : :.:: ::::::: XP_016 NVGMLPNLLPSHFLNAPDE---IQSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGI 80 90 100 110 120 130 200 210 220 230 240 250 pF1KB5 GMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLAKIRKPTLDKPS ...: :: ..:::.:.:: ::. :.:::..: :..: . :: :.: ..: . .. . XP_016 ALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTKYLNTNVITKT 140 150 160 170 180 190 260 270 280 290 300 310 pF1KB5 PETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNKSTRAHYLKKTKK . ::: ... : . ..: : : : ......: .:.: . . ... . .::. : XP_016 ADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAFQ--RLLLTHYVAYLKL 200 210 220 230 240 250 pF1KB5 N : XP_016 NTKVR 312 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 18 17:33:36 2016 done: Fri Nov 18 17:33:37 2016 Total Scan time: 6.050 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]