FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5266, 350 aa 1>>>pF1KB5266 350 - 350 aa - 350 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.2299+/-0.00113; mu= 5.6059+/- 0.066 mean_var=132.4763+/-27.836, 0's: 0 Z-trim(106.0): 138 B-trim: 17 in 1/48 Lambda= 0.111431 statistics sampled from 8591 (8753) to 8591 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.269), width: 16 Scan time: 2.570 The best scores are: opt bits E(32554) CCDS8676.1 STRAP gene_id:11171|Hs108|chr12 ( 350) 2352 390.0 1.5e-108 CCDS54592.1 POC1A gene_id:25886|Hs108|chr3 ( 359) 342 66.9 3e-11 CCDS2846.1 POC1A gene_id:25886|Hs108|chr3 ( 407) 342 66.9 3.3e-11 CCDS31869.1 POC1B gene_id:282809|Hs108|chr12 ( 478) 341 66.8 4.2e-11 CCDS2470.1 DAW1 gene_id:164781|Hs108|chr2 ( 415) 339 66.5 4.6e-11 CCDS54591.1 POC1A gene_id:25886|Hs108|chr3 ( 369) 337 66.1 5.3e-11 >>CCDS8676.1 STRAP gene_id:11171|Hs108|chr12 (350 aa) initn: 2352 init1: 2352 opt: 2352 Z-score: 2062.0 bits: 390.0 E(32554): 1.5e-108 Smith-Waterman score: 2352; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:1-350) 10 20 30 40 50 60 pF1KB5 MAMRQTPLTCSGHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS86 MAMRQTPLTCSGHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 AVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS86 AVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSADDKTVRLWDHATMTEVKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS86 DKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSADDKTVRLWDHATMTEVKSL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 NFNMSVSSMEYIPEGEILVITYGRSIAFHSAVSLDPIKSFEAPATINSASLHPEKEFLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS86 NFNMSVSSMEYIPEGEILVITYGRSIAFHSAVSLDPIKSFEAPATINSASLHPEKEFLVA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 GGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS86 GGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTY 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 GLWKCVLPEEDSGELAKPKIGFPETTEEELEEIASENSDCIFPSAPDVKA :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS86 GLWKCVLPEEDSGELAKPKIGFPETTEEELEEIASENSDCIFPSAPDVKA 310 320 330 340 350 >>CCDS54592.1 POC1A gene_id:25886|Hs108|chr3 (359 aa) initn: 317 init1: 127 opt: 342 Z-score: 315.6 bits: 66.9 E(32554): 3e-11 Smith-Waterman score: 342; 26.4% identity (57.3% similar) in 288 aa overlap (12-294:17-300) 10 20 30 40 50 pF1KB5 MAMRQTPLTCSGHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTF :: :. . :: : : :. :. :. . . : CCDS54 MAAPCAEDPSLERHFKGHRDAVTCVDFSINTKQ---LASGSMDSCLMVWHMKPQSRAYRF 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 LGHKGAVWGATLNKDATKAATAAADFTAKVW-DAVSGDELMTLAHKHIVKTVDFTQDSNY ::: :: .... .. :... : :...: :.:. . :: :..: : .:.. CCDS54 TGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 LLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSA-DDKTVRLWDHAT ..:...:: .... .. . . .: : . .. : . . . :.:: :::::.:::... CCDS54 FVTASDDKTVKVWATHRQKFLFS-LSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 MTEVKSLNFNMS-VSSMEYIPEGE-ILVITYGRSIAFHSAVSLDPIKSFEA-PATINSAS :.: . . :. ... : : : . . .. .. . .. .. :..:. : CCDS54 RECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 LHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLR .:: ..:.... : : : :. : . .:: :: : :: :: .:::. : . CCDS54 FHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVM 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 LWQTVVGKTYGLWKCVLPEEDSGELAKPKIGFPETTEEELEEIASENSDCIFPSAPDVKA .:.. CCDS54 VWKSNFDIVDHGEVTKVPRPPATLASSMGNLTVSILEQRLTLTEDKLKQCLENQQLIMQR 300 310 320 330 340 350 >>CCDS2846.1 POC1A gene_id:25886|Hs108|chr3 (407 aa) initn: 317 init1: 127 opt: 342 Z-score: 314.8 bits: 66.9 E(32554): 3.3e-11 Smith-Waterman score: 342; 26.4% identity (57.3% similar) in 288 aa overlap (12-294:17-300) 10 20 30 40 50 pF1KB5 MAMRQTPLTCSGHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTF :: :. . :: : : :. :. :. . . : CCDS28 MAAPCAEDPSLERHFKGHRDAVTCVDFSINTKQ---LASGSMDSCLMVWHMKPQSRAYRF 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 LGHKGAVWGATLNKDATKAATAAADFTAKVW-DAVSGDELMTLAHKHIVKTVDFTQDSNY ::: :: .... .. :... : :...: :.:. . :: :..: : .:.. CCDS28 TGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 LLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSA-DDKTVRLWDHAT ..:...:: .... .. . . .: : . .. : . . . :.:: :::::.:::... CCDS28 FVTASDDKTVKVWATHRQKFLFS-LSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 MTEVKSLNFNMS-VSSMEYIPEGE-ILVITYGRSIAFHSAVSLDPIKSFEA-PATINSAS :.: . . :. ... : : : . . .. .. . .. .. :..:. : CCDS28 RECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 LHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLR .:: ..:.... : : : :. : . .:: :: : :: :: .:::. : . CCDS28 FHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVM 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 LWQTVVGKTYGLWKCVLPEEDSGELAKPKIGFPETTEEELEEIASENSDCIFPSAPDVKA .:.. CCDS28 VWKSNFDIVDHGEVTKVPRPPATLASSMGNLPEVDFPVPPGRGRSVESVQSQPQEPVSVP 300 310 320 330 340 350 >>CCDS31869.1 POC1B gene_id:282809|Hs108|chr12 (478 aa) initn: 382 init1: 161 opt: 341 Z-score: 312.9 bits: 66.8 E(32554): 4.2e-11 Smith-Waterman score: 341; 25.9% identity (57.6% similar) in 290 aa overlap (12-294:16-299) 10 20 30 40 50 pF1KB5 MAMRQTPLTCSGHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFL :: ...: .: : : : .: : :: . .. CCDS31 MASATEDPVLERYFKGHKAAITSLDLS---PNGKQLATASWDTFLMLWNFKPHARAYRYV 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 GHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTL-AHKHIVKTVDFTQDSNYL ::: .: .. .. .. :.:. : :...: . .. . :: :..:::. :...: CCDS31 GHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 LTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILS-ADDKTVRLWDHATM :...:: ...... . . . :: .. : . . . :.: ..:::...:: .. CCDS31 ATASEDKSIKVWSMYR-QRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNK 120 130 140 150 160 170 180 190 200 210 220 pF1KB5 TEVKSLNFNMSVSSMEYI---PEGEILVITYGRSIAFHSAVSLDPI-KSFEAPAT-INSA :. ::. ::. ... : : .. . . . . : .. . . ... . .: CCDS31 QCVN--NFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCI 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 SLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTL :.:: ..:.... : : : :. . . .:: ::. : :: :::.:::. : . CCDS31 SFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQV 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 RLWQTVVGKTYGLWKCVLPEEDSGELAKPKIGFPETTEEELEEIASENSDCIFPSAPDVK ::.: CCDS31 LLWRTNFDELHCKGLTKRNLKRLHFDSPPHLLDIYPRTPHPHEEKVETVEINPKLEVIDL 300 310 320 330 340 350 >>CCDS2470.1 DAW1 gene_id:164781|Hs108|chr2 (415 aa) initn: 204 init1: 134 opt: 339 Z-score: 312.0 bits: 66.5 E(32554): 4.6e-11 Smith-Waterman score: 339; 26.6% identity (60.7% similar) in 290 aa overlap (9-293:129-415) 10 20 30 pF1KB5 MAMRQTPLTCSGHTRPVVDLAFSGITPYGYFLISACKD : :: : .::. .::: . .. : CCDS24 ALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFN--NPYGDKIATGSFD 100 110 120 130 140 150 40 50 60 70 80 90 pF1KB5 GKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTL- : . .:: :: :: . . ..: ..: .::.. : :::.:: .:.:..:: CCDS24 KTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLR 160 170 180 190 200 210 100 110 120 130 140 150 pF1KB5 AHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQ .:. . ...:. ... ..::. :. . ..: . . . . . :: . :..: . . . CCDS24 GHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGR-KVNILIGHCAEISSASFNWDCSL 220 230 240 250 260 270 160 170 180 190 200 210 pF1KB5 ILSAD-DKTVRLWDHATMTEVKSLN-FNMSVSSMEYIPEGEILVITYGRSIA-FHSAVSL ::... ::: .::: .. : .:. . . . . :.... . . . : . ::.. CCDS24 ILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATR 280 290 300 310 320 330 220 230 240 250 260 270 pF1KB5 DPIKSFEA-PATINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRF : ..:. . :.. :..:. . :..:. : .: ..:. :. .:: : : CCDS24 KCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAF 340 350 360 370 380 390 280 290 300 310 320 330 pF1KB5 SPDGELYASGSEDGTLRLWQTVVGKTYGLWKCVLPEEDSGELAKPKIGFPETTEEELEEI . :.. .::.:.: :.:. CCDS24 NYKGNIVITGSKDNTCRIWR 400 410 >>CCDS54591.1 POC1A gene_id:25886|Hs108|chr3 (369 aa) initn: 264 init1: 127 opt: 337 Z-score: 311.0 bits: 66.1 E(32554): 5.3e-11 Smith-Waterman score: 337; 26.9% identity (60.4% similar) in 245 aa overlap (55-294:19-262) 30 40 50 60 70 80 pF1KB5 ITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAK : ::: :: .... .. :... : :.. CCDS54 MDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVR 10 20 30 40 90 100 110 120 130 140 pF1KB5 VW-DAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHT .: :.:. . :: :..: : .:.. ..:...:: .... .. . . .: : CCDS54 IWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFS-LSQHI 50 60 70 80 90 100 150 160 170 180 190 200 pF1KB5 SGIKKALWCSEDKQILSA-DDKTVRLWDHATMTEVKSLNFNMS-VSSMEYIPEGE-ILVI . .. : . . . :.:: :::::.:::... :.: . . :. ... : : : . CCDS54 NWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAA 110 120 130 140 150 160 210 220 230 240 250 pF1KB5 TYGRSIAFHSAVSLDPIKSFEA-PATINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELE . .. .. . .. .. :..:. :.:: ..:.... : : : :. : CCDS54 GMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLY 170 180 190 200 210 220 260 270 280 290 300 310 pF1KB5 SYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLWKCVLPEEDSGELAKPK . .:: :: : :: :: .:::. : . .:.. CCDS54 TLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSNFDIVDHGEVTKVPRPPATLASSMG 230 240 250 260 270 280 320 330 340 350 pF1KB5 IGFPETTEEELEEIASENSDCIFPSAPDVKA CCDS54 NLPEVDFPVPPGRGRSVESVQSQPQEPVSVPQTLTSTLEHIVGQLDVLTQTVSILEQRLT 290 300 310 320 330 340 350 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:25:23 2016 done: Thu Nov 3 22:25:23 2016 Total Scan time: 2.570 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]