FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5268, 368 aa 1>>>pF1KB5268 368 - 368 aa - 368 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9239+/-0.000281; mu= 12.5154+/- 0.018 mean_var=178.8689+/-39.343, 0's: 0 Z-trim(123.8): 50 B-trim: 4658 in 2/56 Lambda= 0.095897 statistics sampled from 44314 (44394) to 44314 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.8), E-opt: 0.2 (0.521), width: 16 Scan time: 9.430 The best scores are: opt bits E(85289) NP_543141 (OMIM: 606917) probable G-protein couple ( 368) 2464 352.3 1e-96 XP_016857927 (OMIM: 606916) PREDICTED: probable G- ( 451) 346 59.4 1.9e-08 NP_114142 (OMIM: 606916) probable G-protein couple ( 451) 346 59.4 1.9e-08 NP_000862 (OMIM: 601109) 5-hydroxytryptamine recep ( 440) 235 44.0 0.00077 XP_005253267 (OMIM: 118445) PREDICTED: gastrin/cho ( 516) 227 43.0 0.0018 XP_016877086 (OMIM: 607970) PREDICTED: probable G- ( 494) 221 42.1 0.0032 NP_072093 (OMIM: 607970) probable G-protein couple ( 494) 221 42.1 0.0032 XP_016877088 (OMIM: 607970) PREDICTED: probable G- ( 494) 221 42.1 0.0032 XP_016877087 (OMIM: 607970) PREDICTED: probable G- ( 494) 221 42.1 0.0032 XP_016877085 (OMIM: 607970) PREDICTED: probable G- ( 494) 221 42.1 0.0032 >>NP_543141 (OMIM: 606917) probable G-protein coupled re (368 aa) initn: 2464 init1: 2464 opt: 2464 Z-score: 1857.5 bits: 352.3 E(85289): 1e-96 Smith-Waterman score: 2464; 99.5% identity (99.7% similar) in 368 aa overlap (1-368:1-368) 10 20 30 40 50 60 pF1KB5 MANSTGLNASEVAGSLGLILAAVVEVGALLGNGALLVVVLRTPGLRDALYLAHLCVVDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_543 MANSTGLNASEVAGSLGLILAAVVEVGALLGNGALLVVVLRTPGLRDALYLAHLCVVDLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 AAASIMPLGLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_543 AAASIMPLGLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGVAALGLARYRLIVHP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LRPGSRPPPVLVLTAVWAAAGLLGALSLLGPPPAPPPAPARCSVLAGGLGPFRPLWALLA :::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::: NP_543 LRPGSRPPPVLVLTAVWAAAGLLGALSLLGTPPAPPPAPARCSVLAGGLGPFRPLWALLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 FALPALLLLGAYGGIFVVARRAALRPPRPARGSRLRSDSLDSRLSILPPLRPRLPGGKAA :::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::: NP_543 FALPALLLLGAYGGIFVVARRAALRPPRPARGSRLHSDSLDSRLSILPPLRPRLPGGKAA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LAPALAVGQFAACWLPYGCACLAPAARAAEAEAAVTWVAYSAFAAHPFLYGLLQRPVRLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_543 LAPALAVGQFAACWLPYGCACLAPAARAAEAEAAVTWVAYSAFAAHPFLYGLLQRPVRLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 LGRLSRRALPGPVRACTPQAWHPRALLQCLQRPPEGPAVGPSEAPEQTPELAGGRSPAYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_543 LGRLSRRALPGPVRACTPQAWHPRALLQCLQRPPEGPAVGPSEAPEQTPELAGGRSPAYQ 310 320 330 340 350 360 pF1KB5 GPPESSLS :::::::: NP_543 GPPESSLS >>XP_016857927 (OMIM: 606916) PREDICTED: probable G-prot (451 aa) initn: 568 init1: 156 opt: 346 Z-score: 272.8 bits: 59.4 E(85289): 1.9e-08 Smith-Waterman score: 568; 33.9% identity (61.2% similar) in 387 aa overlap (15-366:43-423) 10 20 30 40 pF1KB5 MANSTGLNASEVAGSLGLILAAVVEVGALLGNGALLVVVLRTPG :..:.. .... :. ::.:...:. .::. XP_016 SSTLGRVPQTPGPSTASGVPEVGLRDVASESVALFFMLLLDLTAVAGNAAVMAVIAKTPA 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB5 LRDALYLAHLCVVDLLAAASIMPLGLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTL :: ... :::.:::::: ..:::..:.. . .. .: . :: :::. .. : XP_016 LRKFVFVFHLCLVDLLAALTLMPLAMLSSSAL-FDHALFGEVACRLYLFLSVCFVSLAIL 80 90 100 110 120 130 110 120 130 140 150 pF1KB5 GVAALGLARYRLIVHPLRPGSRPPPVLV---LTAVWAAAGLLGALSLLGP---PPAPPPA .:.:... :: .:::.: : :: :..::. : .... .:: . : . XP_016 SVSAINVERYYYVVHPMRYEVRMTLGLVASVLVGVWVKALAMASVPVLGRVSWEEGAPSV 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB5 PARCSVL---AGGLGPFRPLWALLAFALPALLLLGAYGGIFVVARRAALRP-PRPA--RG : ::. .. : ..:.: : :: ::.: .: ..: ::: ::.. : :. . XP_016 PPGCSLQWSHSAYCQLFVVVFAVLYFLLPLLLILVVYCSMFRVARVAAMQHGPLPTWMET 200 210 220 230 240 250 220 230 240 250 pF1KB5 SRLRSDSLDSRLSIL-----PPLRPR--LPGGKAALAPALAVG-QFAACWLPY-----GC : ::.::.:: ... : :. . :::::.. :::: :: ::::: XP_016 PRQRSESLSSRSTMVTSSGAPQTTPHRTFGGGKAAVV-LLAVGGQFLLCWLPYFSFHLYV 260 270 280 290 300 310 260 270 280 290 300 310 pF1KB5 ACLAPAARAAEAEAAVTWVAYSAFAAHPFLYGLLQRPVRLALGRLSRRAL----PGP--- : : ....:..:::..: :...::.:: :.: .: :.::.. . :.: XP_016 ALSAQPISTGQVESVVTWIGYFCFTSNPFFYGCLNRQIR---GELSKQFVCFFKPAPEEE 320 330 340 350 360 320 330 340 350 360 pF1KB5 VRACTPQAWHPRALLQCLQR---PPEGPAVGPSEAPEQTPELAGGRSPAYQGPPESSLS .: . .. . .:: :: : :. . : .:.: : . : :. : :.: XP_016 LRLPSREGSIEENFLQFLQGTGCPSESWVSRPLPSPKQEPPAVDFRIPG-QIAEETSEFL 370 380 390 400 410 420 XP_016 EQQLTSDIIMSDSYLRPAASPRLES 430 440 450 >>NP_114142 (OMIM: 606916) probable G-protein coupled re (451 aa) initn: 568 init1: 156 opt: 346 Z-score: 272.8 bits: 59.4 E(85289): 1.9e-08 Smith-Waterman score: 568; 33.9% identity (61.2% similar) in 387 aa overlap (15-366:43-423) 10 20 30 40 pF1KB5 MANSTGLNASEVAGSLGLILAAVVEVGALLGNGALLVVVLRTPG :..:.. .... :. ::.:...:. .::. NP_114 SSTLGRVPQTPGPSTASGVPEVGLRDVASESVALFFMLLLDLTAVAGNAAVMAVIAKTPA 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB5 LRDALYLAHLCVVDLLAAASIMPLGLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTL :: ... :::.:::::: ..:::..:.. . .. .: . :: :::. .. : NP_114 LRKFVFVFHLCLVDLLAALTLMPLAMLSSSAL-FDHALFGEVACRLYLFLSVCFVSLAIL 80 90 100 110 120 130 110 120 130 140 150 pF1KB5 GVAALGLARYRLIVHPLRPGSRPPPVLV---LTAVWAAAGLLGALSLLGP---PPAPPPA .:.:... :: .:::.: : :: :..::. : .... .:: . : . NP_114 SVSAINVERYYYVVHPMRYEVRMTLGLVASVLVGVWVKALAMASVPVLGRVSWEEGAPSV 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB5 PARCSVL---AGGLGPFRPLWALLAFALPALLLLGAYGGIFVVARRAALRP-PRPA--RG : ::. .. : ..:.: : :: ::.: .: ..: ::: ::.. : :. . NP_114 PPGCSLQWSHSAYCQLFVVVFAVLYFLLPLLLILVVYCSMFRVARVAAMQHGPLPTWMET 200 210 220 230 240 250 220 230 240 250 pF1KB5 SRLRSDSLDSRLSIL-----PPLRPR--LPGGKAALAPALAVG-QFAACWLPY-----GC : ::.::.:: ... : :. . :::::.. :::: :: ::::: NP_114 PRQRSESLSSRSTMVTSSGAPQTTPHRTFGGGKAAVV-LLAVGGQFLLCWLPYFSFHLYV 260 270 280 290 300 310 260 270 280 290 300 310 pF1KB5 ACLAPAARAAEAEAAVTWVAYSAFAAHPFLYGLLQRPVRLALGRLSRRAL----PGP--- : : ....:..:::..: :...::.:: :.: .: :.::.. . :.: NP_114 ALSAQPISTGQVESVVTWIGYFCFTSNPFFYGCLNRQIR---GELSKQFVCFFKPAPEEE 320 330 340 350 360 320 330 340 350 360 pF1KB5 VRACTPQAWHPRALLQCLQR---PPEGPAVGPSEAPEQTPELAGGRSPAYQGPPESSLS .: . .. . .:: :: : :. . : .:.: : . : :. : :.: NP_114 LRLPSREGSIEENFLQFLQGTGCPSESWVSRPLPSPKQEPPAVDFRIPG-QIAEETSEFL 370 380 390 400 410 420 NP_114 EQQLTSDIIMSDSYLRPAASPRLES 430 440 450 >>NP_000862 (OMIM: 601109) 5-hydroxytryptamine receptor (440 aa) initn: 95 init1: 55 opt: 235 Z-score: 189.9 bits: 44.0 E(85289): 0.00077 Smith-Waterman score: 320; 28.6% identity (50.2% similar) in 402 aa overlap (2-361:9-387) 10 20 30 40 pF1KB5 MANST---GLNASEVAGSLGLILAAVVEVGALLG--NGALLVVVLRTPGLRDA :::: : . . :. : . ::. : :: . :. :.... :.::.. NP_000 MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB5 --LYLAHLCVVDLLAAASIMPLGLLAAPPPGLGRVRLGPAPCRAARFLSAALLPACTLGV ..:. : . ::... .:: ..: : :: :. . : ... : :.. NP_000 SNFFLVSLFTSDLMVGLVVMPPAMLNA---LYGRWVLARGLCLLWTAFDVMCCSASILNL 70 80 90 100 110 110 120 130 140 150 pF1KB5 AALGLARYRLIVHPLRPGSRPPPVLVLTAV---WAAAGLLGALSLL-GPPP---APPPAP ..: :: ::. ::: : :. .:. : :. :.: . : :: : : ::.: NP_000 CLISLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVP 120 130 140 150 160 170 160 170 180 190 200 pF1KB5 ARCSVLAGGLGPFRPLWALLAFALPALLLLGAYGGIFVVARRAA---------------- ..: .::. :: . . :.: ::. . .: :...::. : NP_000 GQCRLLAS--LPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASE 180 190 200 210 220 230 210 220 230 240 250 pF1KB5 -LRPPRPARGSRLRSDSLDSRLSILPPLRPRLPGGKAALAPALAVGQFAACWLPYG---- :. :: : . .: ::: : : ::.:. .. .:.: . :::. NP_000 TLQVPRTPRPG---VESADSRRLATKHSRKAL---KASLTLGILLGMFFVTWLPFFVANI 240 250 260 270 280 260 270 280 290 300 310 pF1KB5 ----CACLAPAARAAEAEAAVTWVAYSAFAAHPFLYGLLQRPVRLALGRLSRRALPGPVR : :..:. ..::..: . .:..: :..: . ::::. :: : NP_000 VQAVCDCISPGL-----FDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRF----LPCP-- 290 300 310 320 330 320 330 340 350 360 pF1KB5 ACTPQAWHPRALLQCLQRPPEGPAVGPSEA---PEQTPELAGGRSPAYQGPPESSLS : :. . :. :: : : : : . . : : .: NP_000 RC-PRERQASLASPSLRTSHSGPRPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQ 340 350 360 370 380 390 NP_000 LLLPGEATQDPPLPTRAAAAVNFFNIDPAEPELRPHPLGIPTN 400 410 420 430 440 >>XP_005253267 (OMIM: 118445) PREDICTED: gastrin/cholecy (516 aa) initn: 133 init1: 59 opt: 227 Z-score: 183.1 bits: 43.0 E(85289): 0.0018 Smith-Waterman score: 227; 25.6% identity (48.0% similar) in 379 aa overlap (6-355:46-399) 10 20 30 pF1KB5 MANSTGLNASEVAGSLGLILAAVVEVGALLGNGAL : .. :. .. . : ::. . .. :: . XP_005 GPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLI 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB5 LVVVLRTPGLRDAL--YLAHLCVVDLLAAASIMPLGLLAAPPPGLGRVRLGPAPCRAARF .::. . :: . .: : : ::: :.. ::. :: : .: .: . :.:. . XP_005 IVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLL---PNLMGTFIFGTVICKAVSY 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB5 LSAALLPACTLGVAALGLARYRLIVHPLRP---GSRPPPVLVLTAVWAAAGLLGALSLLG : .. . . ::...:..: :: : .::. .: . :..:.: .:: :. XP_005 LMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWLLSGL-----LMV 140 150 160 170 180 160 170 180 190 200 pF1KB5 PPPA----PPPAPA--RCSVLAGGLGPFRPLWA----LLAFALPALLLLGAYGGIFVVAR : :. : .: .: : . : :. :: : .:.... ::: ...: XP_005 PYPVYTVVQPVGPRVLQC-VHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYG---LISR 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB5 RAALRPPRPARGSRLRSDSLDSRLSILPPLRPRLPGGKAALAPALAVGQFAACWLPYGCA . : : :. .:: :: . . :::: . :. ... : : . XP_005 ELYL-------GLRFDGDS-DSDSQSRVRNQGGLPGGAGPREQNLGEAELWRATGPAGVG 250 260 270 280 290 270 280 290 300 pF1KB5 CLAPAARAAEA-EAAVTWVAYS-------------AFAAHPFLYGLLQRPVRLALGRLSR .:. . : ..: : ...:::. : ... : : XP_005 GTEMKVRVRRKLEMELSWERRSGGDWAGDWGDSPFSLTAHPLCSGAVHQNGRC---RPET 300 310 320 330 340 350 310 320 330 340 350 360 pF1KB5 RALPGPVRACTPQAWHPRALLQCLQRPPEGPAVGPSEAPEQTPELAGGRSPAYQGPPESS :. .: : . : :. ::. : : :. :: : XP_005 GAVGEDSDGCYVQLPRSRPALELTALTAPGPGSGSR--PTQAKLLAKKRVVRMLLVIVVL 360 370 380 390 400 410 pF1KB5 LS XP_005 FFLCWLPVYSANTWRAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQAC 420 430 440 450 460 470 >>XP_016877086 (OMIM: 607970) PREDICTED: probable G-prot (494 aa) initn: 166 init1: 69 opt: 221 Z-score: 178.9 bits: 42.1 E(85289): 0.0032 Smith-Waterman score: 221; 24.9% identity (51.8% similar) in 313 aa overlap (7-303:97-400) 10 20 30 pF1KB5 MANSTGLNASEVAGSLGLILAAVVEVGALLGNGALL :. . .... .:.: . ...: :: :.. XP_016 PGGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSL-GNCAVM 70 80 90 100 110 120 40 50 60 70 80 pF1KB5 VVVLRTPGLRDAL--YLAHLCVVDLLAAASIMPLGLLAA-PPPGLGRVRLGPAP----CR :... :: . .. : . :::.: .: ..: ::: . . .: : XP_016 GVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPGGSAPAAAAGPWRGFCA 130 140 150 160 170 180 90 100 110 120 130 140 pF1KB5 AARFLSAALLPACTLGVAALGLARYRLIVHPLRPG-SRPPPVLVLTAVWAAA-GLLGALS :.::.:. . . ::.:: ..: :: ::.: : .: . .:...: .: :. XP_016 ASRFFSSCFGIVSTLSVALISLDRYCAIVRPPREKIGRRRALQLLAGAWLTALGFSLPWE 190 200 210 220 230 240 150 160 170 180 190 200 pF1KB5 LLGPPPAPPPAPARCSVLAGGLGPFRPLWALLAFALPALLLLGAYGGIFVVARRAALRPP ::: : : . . : : : : :. :. . :... : :.. . XP_016 LLGAPRELAAAQS----FHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHIC 250 260 270 280 290 300 210 220 230 240 250 260 pF1KB5 RPARGSRLRSDSLDSRLSILPPLRPRLPGGKAALAPALAVGQFAACWLPYGCACLAPAAR . .: : .: ... .: . ..: . . . :: :: : ::: XP_016 KTVRLSDVRVRPVNTYARVLRFFSEV----RTATTVLIMIVFVICCWGPYCFLVLLAAAR 310 320 330 340 350 270 280 290 300 310 320 pF1KB5 AAEAEAA-------VTWVAYSAFAAHPFLYGLLQRPVRLALGRLSRRALPGPVRACTPQA :.. : ..:.... : .: .:.. . . . ::: XP_016 QAQTMQAPSLLSVVAVWLTWANGAINPVIYAIRNPNISMLLGRNREEGYRTRNVDAFLPS 360 370 380 390 400 410 330 340 350 360 pF1KB5 WHPRALLQCLQRPPEGPAVGPSEAPEQTPELAGGRSPAYQGPPESSLS XP_016 QGPGLQARSRSRLRNRYANRLGACNRMSSSNPASGVAGDVAMWARKNPVVLFCREGPPEP 420 430 440 450 460 470 >>NP_072093 (OMIM: 607970) probable G-protein coupled re (494 aa) initn: 166 init1: 69 opt: 221 Z-score: 178.9 bits: 42.1 E(85289): 0.0032 Smith-Waterman score: 221; 24.9% identity (51.8% similar) in 313 aa overlap (7-303:97-400) 10 20 30 pF1KB5 MANSTGLNASEVAGSLGLILAAVVEVGALLGNGALL :. . .... .:.: . ...: :: :.. NP_072 PGGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSL-GNCAVM 70 80 90 100 110 120 40 50 60 70 80 pF1KB5 VVVLRTPGLRDAL--YLAHLCVVDLLAAASIMPLGLLAA-PPPGLGRVRLGPAP----CR :... :: . .. : . :::.: .: ..: ::: . . .: : NP_072 GVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPGGSAPAAAAGPWRGFCA 130 140 150 160 170 180 90 100 110 120 130 140 pF1KB5 AARFLSAALLPACTLGVAALGLARYRLIVHPLRPG-SRPPPVLVLTAVWAAA-GLLGALS :.::.:. . . ::.:: ..: :: ::.: : .: . .:...: .: :. NP_072 ASRFFSSCFGIVSTLSVALISLDRYCAIVRPPREKIGRRRALQLLAGAWLTALGFSLPWE 190 200 210 220 230 240 150 160 170 180 190 200 pF1KB5 LLGPPPAPPPAPARCSVLAGGLGPFRPLWALLAFALPALLLLGAYGGIFVVARRAALRPP ::: : : . . : : : : :. :. . :... : :.. . NP_072 LLGAPRELAAAQS----FHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHIC 250 260 270 280 290 300 210 220 230 240 250 260 pF1KB5 RPARGSRLRSDSLDSRLSILPPLRPRLPGGKAALAPALAVGQFAACWLPYGCACLAPAAR . .: : .: ... .: . ..: . . . :: :: : ::: NP_072 KTVRLSDVRVRPVNTYARVLRFFSEV----RTATTVLIMIVFVICCWGPYCFLVLLAAAR 310 320 330 340 350 270 280 290 300 310 320 pF1KB5 AAEAEAA-------VTWVAYSAFAAHPFLYGLLQRPVRLALGRLSRRALPGPVRACTPQA :.. : ..:.... : .: .:.. . . . ::: NP_072 QAQTMQAPSLLSVVAVWLTWANGAINPVIYAIRNPNISMLLGRNREEGYRTRNVDAFLPS 360 370 380 390 400 410 330 340 350 360 pF1KB5 WHPRALLQCLQRPPEGPAVGPSEAPEQTPELAGGRSPAYQGPPESSLS NP_072 QGPGLQARSRSRLRNRYANRLGACNRMSSSNPASGVAGDVAMWARKNPVVLFCREGPPEP 420 430 440 450 460 470 >>XP_016877088 (OMIM: 607970) PREDICTED: probable G-prot (494 aa) initn: 166 init1: 69 opt: 221 Z-score: 178.9 bits: 42.1 E(85289): 0.0032 Smith-Waterman score: 221; 24.9% identity (51.8% similar) in 313 aa overlap (7-303:97-400) 10 20 30 pF1KB5 MANSTGLNASEVAGSLGLILAAVVEVGALLGNGALL :. . .... .:.: . ...: :: :.. XP_016 PGGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSL-GNCAVM 70 80 90 100 110 120 40 50 60 70 80 pF1KB5 VVVLRTPGLRDAL--YLAHLCVVDLLAAASIMPLGLLAA-PPPGLGRVRLGPAP----CR :... :: . .. : . :::.: .: ..: ::: . . .: : XP_016 GVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPGGSAPAAAAGPWRGFCA 130 140 150 160 170 180 90 100 110 120 130 140 pF1KB5 AARFLSAALLPACTLGVAALGLARYRLIVHPLRPG-SRPPPVLVLTAVWAAA-GLLGALS :.::.:. . . ::.:: ..: :: ::.: : .: . .:...: .: :. XP_016 ASRFFSSCFGIVSTLSVALISLDRYCAIVRPPREKIGRRRALQLLAGAWLTALGFSLPWE 190 200 210 220 230 240 150 160 170 180 190 200 pF1KB5 LLGPPPAPPPAPARCSVLAGGLGPFRPLWALLAFALPALLLLGAYGGIFVVARRAALRPP ::: : : . . : : : : :. :. . :... : :.. . XP_016 LLGAPRELAAAQS----FHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHIC 250 260 270 280 290 300 210 220 230 240 250 260 pF1KB5 RPARGSRLRSDSLDSRLSILPPLRPRLPGGKAALAPALAVGQFAACWLPYGCACLAPAAR . .: : .: ... .: . ..: . . . :: :: : ::: XP_016 KTVRLSDVRVRPVNTYARVLRFFSEV----RTATTVLIMIVFVICCWGPYCFLVLLAAAR 310 320 330 340 350 270 280 290 300 310 320 pF1KB5 AAEAEAA-------VTWVAYSAFAAHPFLYGLLQRPVRLALGRLSRRALPGPVRACTPQA :.. : ..:.... : .: .:.. . . . ::: XP_016 QAQTMQAPSLLSVVAVWLTWANGAINPVIYAIRNPNISMLLGRNREEGYRTRNVDAFLPS 360 370 380 390 400 410 330 340 350 360 pF1KB5 WHPRALLQCLQRPPEGPAVGPSEAPEQTPELAGGRSPAYQGPPESSLS XP_016 QGPGLQARSRSRLRNRYANRLGACNRMSSSNPASGVAGDVAMWARKNPVVLFCREGPPEP 420 430 440 450 460 470 >>XP_016877087 (OMIM: 607970) PREDICTED: probable G-prot (494 aa) initn: 166 init1: 69 opt: 221 Z-score: 178.9 bits: 42.1 E(85289): 0.0032 Smith-Waterman score: 221; 24.9% identity (51.8% similar) in 313 aa overlap (7-303:97-400) 10 20 30 pF1KB5 MANSTGLNASEVAGSLGLILAAVVEVGALLGNGALL :. . .... .:.: . ...: :: :.. XP_016 PGGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSL-GNCAVM 70 80 90 100 110 120 40 50 60 70 80 pF1KB5 VVVLRTPGLRDAL--YLAHLCVVDLLAAASIMPLGLLAA-PPPGLGRVRLGPAP----CR :... :: . .. : . :::.: .: ..: ::: . . .: : XP_016 GVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPGGSAPAAAAGPWRGFCA 130 140 150 160 170 180 90 100 110 120 130 140 pF1KB5 AARFLSAALLPACTLGVAALGLARYRLIVHPLRPG-SRPPPVLVLTAVWAAA-GLLGALS :.::.:. . . ::.:: ..: :: ::.: : .: . .:...: .: :. XP_016 ASRFFSSCFGIVSTLSVALISLDRYCAIVRPPREKIGRRRALQLLAGAWLTALGFSLPWE 190 200 210 220 230 240 150 160 170 180 190 200 pF1KB5 LLGPPPAPPPAPARCSVLAGGLGPFRPLWALLAFALPALLLLGAYGGIFVVARRAALRPP ::: : : . . : : : : :. :. . :... : :.. . XP_016 LLGAPRELAAAQS----FHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHIC 250 260 270 280 290 300 210 220 230 240 250 260 pF1KB5 RPARGSRLRSDSLDSRLSILPPLRPRLPGGKAALAPALAVGQFAACWLPYGCACLAPAAR . .: : .: ... .: . ..: . . . :: :: : ::: XP_016 KTVRLSDVRVRPVNTYARVLRFFSEV----RTATTVLIMIVFVICCWGPYCFLVLLAAAR 310 320 330 340 350 270 280 290 300 310 320 pF1KB5 AAEAEAA-------VTWVAYSAFAAHPFLYGLLQRPVRLALGRLSRRALPGPVRACTPQA :.. : ..:.... : .: .:.. . . . ::: XP_016 QAQTMQAPSLLSVVAVWLTWANGAINPVIYAIRNPNISMLLGRNREEGYRTRNVDAFLPS 360 370 380 390 400 410 330 340 350 360 pF1KB5 WHPRALLQCLQRPPEGPAVGPSEAPEQTPELAGGRSPAYQGPPESSLS XP_016 QGPGLQARSRSRLRNRYANRLGACNRMSSSNPASGVAGDVAMWARKNPVVLFCREGPPEP 420 430 440 450 460 470 >>XP_016877085 (OMIM: 607970) PREDICTED: probable G-prot (494 aa) initn: 166 init1: 69 opt: 221 Z-score: 178.9 bits: 42.1 E(85289): 0.0032 Smith-Waterman score: 221; 24.9% identity (51.8% similar) in 313 aa overlap (7-303:97-400) 10 20 30 pF1KB5 MANSTGLNASEVAGSLGLILAAVVEVGALLGNGALL :. . .... .:.: . ...: :: :.. XP_016 PGGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSL-GNCAVM 70 80 90 100 110 120 40 50 60 70 80 pF1KB5 VVVLRTPGLRDAL--YLAHLCVVDLLAAASIMPLGLLAA-PPPGLGRVRLGPAP----CR :... :: . .. : . :::.: .: ..: ::: . . .: : XP_016 GVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPGGSAPAAAAGPWRGFCA 130 140 150 160 170 180 90 100 110 120 130 140 pF1KB5 AARFLSAALLPACTLGVAALGLARYRLIVHPLRPG-SRPPPVLVLTAVWAAA-GLLGALS :.::.:. . . ::.:: ..: :: ::.: : .: . .:...: .: :. XP_016 ASRFFSSCFGIVSTLSVALISLDRYCAIVRPPREKIGRRRALQLLAGAWLTALGFSLPWE 190 200 210 220 230 240 150 160 170 180 190 200 pF1KB5 LLGPPPAPPPAPARCSVLAGGLGPFRPLWALLAFALPALLLLGAYGGIFVVARRAALRPP ::: : : . . : : : : :. :. . :... : :.. . XP_016 LLGAPRELAAAQS----FHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHIC 250 260 270 280 290 300 210 220 230 240 250 260 pF1KB5 RPARGSRLRSDSLDSRLSILPPLRPRLPGGKAALAPALAVGQFAACWLPYGCACLAPAAR . .: : .: ... .: . ..: . . . :: :: : ::: XP_016 KTVRLSDVRVRPVNTYARVLRFFSEV----RTATTVLIMIVFVICCWGPYCFLVLLAAAR 310 320 330 340 350 270 280 290 300 310 320 pF1KB5 AAEAEAA-------VTWVAYSAFAAHPFLYGLLQRPVRLALGRLSRRALPGPVRACTPQA :.. : ..:.... : .: .:.. . . . ::: XP_016 QAQTMQAPSLLSVVAVWLTWANGAINPVIYAIRNPNISMLLGRNREEGYRTRNVDAFLPS 360 370 380 390 400 410 330 340 350 360 pF1KB5 WHPRALLQCLQRPPEGPAVGPSEAPEQTPELAGGRSPAYQGPPESSLS XP_016 QGPGLQARSRSRLRNRYANRLGACNRMSSSNPASGVAGDVAMWARKNPVVLFCREGPPEP 420 430 440 450 460 470 368 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 16:29:10 2016 done: Thu Nov 3 16:29:12 2016 Total Scan time: 9.430 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]