FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5280, 246 aa 1>>>pF1KB5280 246 - 246 aa - 246 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8549+/-0.000989; mu= 12.2893+/- 0.060 mean_var=80.3947+/-15.685, 0's: 0 Z-trim(104.6): 32 B-trim: 0 in 0/51 Lambda= 0.143041 statistics sampled from 7971 (7989) to 7971 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.245), width: 16 Scan time: 2.170 The best scores are: opt bits E(32554) CCDS13901.1 YWHAH gene_id:7533|Hs108|chr22 ( 246) 1571 333.8 6.7e-92 CCDS5584.1 YWHAG gene_id:7532|Hs108|chr7 ( 247) 1387 295.8 1.8e-80 CCDS6290.1 YWHAZ gene_id:7534|Hs108|chr8 ( 245) 1157 248.3 3.5e-66 CCDS13339.1 YWHAB gene_id:7529|Hs108|chr20 ( 246) 1150 246.9 9.5e-66 CCDS1666.1 YWHAQ gene_id:10971|Hs108|chr2 ( 245) 1107 238.0 4.4e-63 CCDS288.1 SFN gene_id:2810|Hs108|chr1 ( 248) 1012 218.4 3.6e-57 CCDS11001.1 YWHAE gene_id:7531|Hs108|chr17 ( 255) 986 213.0 1.5e-55 >>CCDS13901.1 YWHAH gene_id:7533|Hs108|chr22 (246 aa) initn: 1571 init1: 1571 opt: 1571 Z-score: 1763.4 bits: 333.8 E(32554): 6.7e-92 Smith-Waterman score: 1571; 100.0% identity (100.0% similar) in 246 aa overlap (1-246:1-246) 10 20 30 40 50 60 pF1KB5 MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 RVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 RVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDE 190 200 210 220 230 240 pF1KB5 EAGEGN :::::: CCDS13 EAGEGN >>CCDS5584.1 YWHAG gene_id:7532|Hs108|chr7 (247 aa) initn: 1387 init1: 1387 opt: 1387 Z-score: 1558.2 bits: 295.8 E(32554): 1.8e-80 Smith-Waterman score: 1387; 87.0% identity (95.9% similar) in 246 aa overlap (1-246:1-246) 10 20 30 40 50 60 pF1KB5 MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSW : :::::.:.::::::::::::::.::: :::::::::::.::::::::::::::::::: CCDS55 MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 RVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESK :::::::::: :::::::.: :.:::::::::::.::.:::::::..:::::.. ::::: CCDS55 RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFS ::::::::::::::::::.:::. .:::.:: ::.:: :::::.::::::::::::::.: CCDS55 VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDE :::::::::::::: ::: ::::::::::::::::::::::::::::::::::::::::. CCDS55 VFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDD 190 200 210 220 230 240 pF1KB5 EAGEGN ..:::: CCDS55 DGGEGNN >>CCDS6290.1 YWHAZ gene_id:7534|Hs108|chr8 (245 aa) initn: 1019 init1: 668 opt: 1157 Z-score: 1301.7 bits: 248.3 E(32554): 3.5e-66 Smith-Waterman score: 1157; 75.5% identity (89.4% similar) in 245 aa overlap (3-245:2-242) 10 20 30 40 50 60 pF1KB5 MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSW :...:.:.:.::::::::::::. ::.::: . ::::.::::::::::::::::::: CCDS62 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSW 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 RVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESK ::.::::::: .: ::: . .. :::::: ::. .::::::::.:::: : . : ::: CCDS62 RVVSSIEQKT--EGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNAS--QAESK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 VFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFS ::::::::::::::::::.:. :...:. :. ::.:::::::..:::::::::::::::: CCDS62 VFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFS 120 130 140 150 160 170 190 200 210 220 230 pF1KB5 VFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQ-D :::::: :.::.:: ::: :::.::::::::.:.:::::::::::::::::::::: : : CCDS62 VFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGD 180 190 200 210 220 230 240 pF1KB5 E-EAGEGN : ::::: CCDS62 EAEAGEGGEN 240 >>CCDS13339.1 YWHAB gene_id:7529|Hs108|chr20 (246 aa) initn: 1003 init1: 658 opt: 1150 Z-score: 1293.9 bits: 246.9 E(32554): 9.5e-66 Smith-Waterman score: 1150; 75.5% identity (89.0% similar) in 245 aa overlap (3-245:4-244) 10 20 30 40 50 pF1KB5 MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSS :. .:.:.:.::::::::::::.::::::: .. ::::.:::::::::::::::::: CCDS13 MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 WRVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYES ::::::::::: . :::: . : :::::: ::. .::::: ::::.:: : . : :: CCDS13 WRVISSIEQKT--ERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNAT--QPES 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 KVFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNF :::::::::::.:::.:::::..:...: :. ::.:::::::..::::::::::::::: CCDS13 KVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 SVFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQD ::::::: :.::.:: ::: :::.::::::::::.:::::::::::::::::::::..: CCDS13 SVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQG 180 190 200 210 220 230 240 pF1KB5 EE--AGEGN .: :::: CCDS13 DEGDAGEGEN 240 >>CCDS1666.1 YWHAQ gene_id:10971|Hs108|chr2 (245 aa) initn: 968 init1: 647 opt: 1107 Z-score: 1245.9 bits: 238.0 E(32554): 4.4e-63 Smith-Waterman score: 1107; 71.4% identity (88.2% similar) in 245 aa overlap (3-245:2-242) 10 20 30 40 50 60 pF1KB5 MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSW .. .:.:.:.::::::::::::. :::::: . ::::.:::::::::::::.:::.: CCDS16 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAW 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 RVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESK :::::::::: : ..:::. .: ::::.:.::...:. :: ::::.:: : .. ::: CCDS16 RVISSIEQKT--DTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATN--PESK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 VFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFS ::::::::::.::::::: :. ...... :..::.:::.:::..:::::::::::::::: CCDS16 VFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 VFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDE :::::: : :: :: ::: :::.:::::::::::::::::::::::::::::::::. : CCDS16 VFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGE 180 190 200 210 220 230 pF1KB5 E--AGEGN : :.:: CCDS16 ECDAAEGAEN 240 >>CCDS288.1 SFN gene_id:2810|Hs108|chr1 (248 aa) initn: 981 init1: 596 opt: 1012 Z-score: 1139.9 bits: 218.4 E(32554): 3.6e-57 Smith-Waterman score: 1012; 64.5% identity (88.4% similar) in 242 aa overlap (3-244:2-241) 10 20 30 40 50 60 pF1KB5 MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSW .: .:.:.:.::::::::.:::. ::...: .: :: :.:::::::::::::..:..: CCDS28 MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAW 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 RVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESK ::.::::::. .:.:.: .:. ::::.: ::. ::. ::.:::. :::. .: ::. CCDS28 RVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGD--AESR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 VFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFS ::::::::::::::::::.:. :. .......::.::..:::..: ::.::::::::::: CCDS28 VFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 VFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDE ::.::: :.::.: ::: .::.:.:.: ::.::::::::::::::::::::::.:. : CCDS28 VFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGE 180 190 200 210 220 230 pF1KB5 EAGEGN :.:: CCDS28 EGGEAPQEPQS 240 >>CCDS11001.1 YWHAE gene_id:7531|Hs108|chr17 (255 aa) initn: 1010 init1: 579 opt: 986 Z-score: 1110.7 bits: 213.0 E(32554): 1.5e-55 Smith-Waterman score: 986; 63.8% identity (82.5% similar) in 240 aa overlap (1-240:1-238) 10 20 30 40 50 60 pF1KB5 MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSW : :::.:. .:.:::::::::.:. .:: :. .. :. :.:::::::::::.::::.:: CCDS11 MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 RVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESK :.::::::: :.: ::. .. ::. .: ::. .: :.:..::: :: : ::: CCDS11 RIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANT--GESK 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 VFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFS ::: ::::::.::::: :.:. .. ..: : .::: : .:. .. :::::::::::::: CCDS11 VFYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 VFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDE :::::: :.:..:: ::: ::::::::::::.:.::::::::::::::::::::::.: . CCDS11 VFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGD 180 190 200 210 220 230 pF1KB5 EAGEGN CCDS11 GEEQNKEALQDVEDENQ 240 250 246 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 16:30:24 2016 done: Thu Nov 3 16:30:24 2016 Total Scan time: 2.170 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]