FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5284, 189 aa 1>>>pF1KB5284 189 - 189 aa - 189 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.0372+/-0.0009; mu= 1.8570+/- 0.054 mean_var=189.1288+/-37.227, 0's: 0 Z-trim(112.0): 18 B-trim: 15 in 1/52 Lambda= 0.093260 statistics sampled from 12808 (12820) to 12808 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.394), width: 16 Scan time: 2.270 The best scores are: opt bits E(32554) CCDS64852.1 STMN4 gene_id:81551|Hs108|chr8 ( 189) 1219 175.4 1.8e-44 CCDS64851.1 STMN4 gene_id:81551|Hs108|chr8 ( 167) 1052 152.9 9.8e-38 CCDS6055.1 STMN4 gene_id:81551|Hs108|chr8 ( 216) 985 144.0 6.1e-35 CCDS64854.1 STMN4 gene_id:81551|Hs108|chr8 ( 203) 871 128.6 2.4e-30 CCDS269.1 STMN1 gene_id:3925|Hs108|chr1 ( 149) 623 95.1 2.1e-20 CCDS43748.1 STMN2 gene_id:11075|Hs108|chr8 ( 179) 601 92.2 1.9e-19 CCDS63330.1 STMN3 gene_id:50861|Hs108|chr20 ( 169) 562 87.0 6.9e-18 CCDS13529.1 STMN3 gene_id:50861|Hs108|chr20 ( 180) 562 87.0 7.3e-18 CCDS44090.1 STMN1 gene_id:3925|Hs108|chr1 ( 174) 542 84.3 4.6e-17 CCDS56542.1 STMN2 gene_id:11075|Hs108|chr8 ( 187) 529 82.6 1.6e-16 >>CCDS64852.1 STMN4 gene_id:81551|Hs108|chr8 (189 aa) initn: 1219 init1: 1219 opt: 1219 Z-score: 911.7 bits: 175.4 E(32554): 1.8e-44 Smith-Waterman score: 1219; 100.0% identity (100.0% similar) in 189 aa overlap (1-189:1-189) 10 20 30 40 50 60 pF1KB5 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKCTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKCTS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GQSFEVILKPPSFDGVPEFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 GQSFEVILKPPSFDGVPEFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 EHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVRKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 EHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVRKN 130 140 150 160 170 180 pF1KB5 KELKEEASR ::::::::: CCDS64 KELKEEASR >>CCDS64851.1 STMN4 gene_id:81551|Hs108|chr8 (167 aa) initn: 1052 init1: 1052 opt: 1052 Z-score: 791.0 bits: 152.9 E(32554): 9.8e-38 Smith-Waterman score: 1052; 98.2% identity (98.8% similar) in 165 aa overlap (10-174:1-165) 10 20 30 40 50 60 pF1KB5 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKCTS ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 MKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKCTS 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 GQSFEVILKPPSFDGVPEFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 GQSFEVILKPPSFDGVPEFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 EHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVRKN ::::::::::::::::::::::::::::::::::::::::::::::::::. : CCDS64 EHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKEPPAAR 120 130 140 150 160 pF1KB5 KELKEEASR >>CCDS6055.1 STMN4 gene_id:81551|Hs108|chr8 (216 aa) initn: 984 init1: 984 opt: 985 Z-score: 740.7 bits: 144.0 E(32554): 6.1e-35 Smith-Waterman score: 1155; 87.5% identity (87.5% similar) in 216 aa overlap (1-189:1-216) 10 20 30 pF1KB5 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYE------------------------ :::::::::::::::::::::::::::::::::::: CCDS60 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEGWCGRQCRRKDESQRKDSADWRER 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 ---ADTVDLNWCVISDMEVIELNKCTSGQSFEVILKPPSFDGVPEFNASLPRRRDPSLEE ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RAQADTVDLNWCVISDMEVIELNKCTSGQSFEVILKPPSFDGVPEFNASLPRRRDPSLEE 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 IQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 IQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNK 130 140 150 160 170 180 160 170 180 pF1KB5 ENREAHLAAMLERLQEKDKHAEEVRKNKELKEEASR :::::::::::::::::::::::::::::::::::: CCDS60 ENREAHLAAMLERLQEKDKHAEEVRKNKELKEEASR 190 200 210 >>CCDS64854.1 STMN4 gene_id:81551|Hs108|chr8 (203 aa) initn: 1091 init1: 867 opt: 871 Z-score: 658.2 bits: 128.6 E(32554): 2.4e-30 Smith-Waterman score: 1041; 85.1% identity (85.6% similar) in 201 aa overlap (1-174:1-201) 10 20 30 pF1KB5 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYE------------------------ :::::::::::::::::::::::::::::::::::: CCDS64 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEGWCGRQCRRKDESQRKDSADWRER 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 ---ADTVDLNWCVISDMEVIELNKCTSGQSFEVILKPPSFDGVPEFNASLPRRRDPSLEE ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 RAQADTVDLNWCVISDMEVIELNKCTSGQSFEVILKPPSFDGVPEFNASLPRRRDPSLEE 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 IQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 IQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNK 130 140 150 160 170 180 160 170 180 pF1KB5 ENREAHLAAMLERLQEKDKHAEEVRKNKELKEEASR :::::::::::::::::. : CCDS64 ENREAHLAAMLERLQEKEPPAAR 190 200 >>CCDS269.1 STMN1 gene_id:3925|Hs108|chr1 (149 aa) initn: 711 init1: 623 opt: 623 Z-score: 479.7 bits: 95.1 E(32554): 2.1e-20 Smith-Waterman score: 623; 72.1% identity (90.0% similar) in 140 aa overlap (48-187:4-143) 20 30 40 50 60 70 pF1KB5 LFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKCTSGQSFEVILKPPSFDGVP ::..: ::.: .:::.::.::.: : ..:: CCDS26 MASSDIQVKELEKRASGQAFELILSPRSKESVP 10 20 30 80 90 100 110 120 130 pF1KB5 EFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNF :: : :...: ::::::::::::::::: .:::.::.::::::::.::.:::::::::: CCDS26 EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNF 40 50 60 70 80 90 140 150 160 170 180 pF1KB5 IKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVRKNKELKEEASR :::.:::..:::.:::::::..:: ::::.::::: :::::::: :. : CCDS26 SKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD 100 110 120 130 140 >>CCDS43748.1 STMN2 gene_id:11075|Hs108|chr8 (179 aa) initn: 755 init1: 590 opt: 601 Z-score: 462.6 bits: 92.2 E(32554): 1.9e-19 Smith-Waterman score: 698; 63.3% identity (80.3% similar) in 188 aa overlap (2-188:4-178) 10 20 30 40 50 pF1KB5 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKC : ::::::::: ..::.:::: .: : . : :. :::: ..:: CCDS43 MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYD------------DMEVKQINKR 10 20 30 40 60 70 80 90 100 110 pF1KB5 TSGQSFEVILKPPS-FDGVPEFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLA .:::.::.:::::: .. .:. :: :...: ::::::::::::::::: :::..::.:: CCDS43 ASGQAFELILKPPSPISEAPRTLAS-PKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLA 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB5 EKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEV :::::::::.:::.:::::: :::.::: :::. ::::::.:::..::::::..:: :: CCDS43 EKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEV 110 120 130 140 150 160 180 pF1KB5 RKNKELKEEASR :.::::. : : CCDS43 RRNKELQVELSG 170 >>CCDS63330.1 STMN3 gene_id:50861|Hs108|chr20 (169 aa) initn: 661 init1: 438 opt: 562 Z-score: 434.6 bits: 87.0 E(32554): 6.9e-18 Smith-Waterman score: 624; 59.1% identity (78.5% similar) in 181 aa overlap (10-188:1-168) 10 20 30 40 50 60 pF1KB5 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKCTS :::: ..::.:::: ..: .. :.: .:::: .:.: .: CCDS63 MKELSVLSLICSCFYTQPHPNTVYQY------------GDMEVKQLDKRAS 10 20 30 70 80 90 100 110 pF1KB5 GQSFEVILKPPSFDGVPE--FNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAE ::::::::: :: : :: . .: :...: ::::.::.::::::::: :::..::.::: CCDS63 GQSFEVILKSPS-DLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAE 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB5 KREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVR .:::::::..::.:::::: ..:.::: ::: .:: :::::::. :::.::. :: ::: CCDS63 RREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVR 100 110 120 130 140 150 180 pF1KB5 KNKELKEEASR .::: .:: : CCDS63 RNKEQREEMSG 160 >>CCDS13529.1 STMN3 gene_id:50861|Hs108|chr20 (180 aa) initn: 700 init1: 438 opt: 562 Z-score: 434.2 bits: 87.0 E(32554): 7.3e-18 Smith-Waterman score: 663; 59.8% identity (79.4% similar) in 189 aa overlap (2-188:4-179) 10 20 30 40 50 pF1KB5 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKC :..::::::::: ..::.:::: ..: .. :.: .:::: .:.: CCDS13 MASTISAYKEKMKELSVLSLICSCFYTQPHPNTVYQY------------GDMEVKQLDKR 10 20 30 40 60 70 80 90 100 110 pF1KB5 TSGQSFEVILKPPSFDGVPE--FNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHL .:::::::::: :: : :: . .: :...: ::::.::.::::::::: :::..::.: CCDS13 ASGQSFEVILKSPS-DLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQL 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB5 AEKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEE ::.:::::::..::.:::::: ..:.::: ::: .:: :::::::. :::.::. :: : CCDS13 AERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAE 110 120 130 140 150 160 180 pF1KB5 VRKNKELKEEASR ::.::: .:: : CCDS13 VRRNKEQREEMSG 170 180 >>CCDS44090.1 STMN1 gene_id:3925|Hs108|chr1 (174 aa) initn: 542 init1: 542 opt: 542 Z-score: 419.9 bits: 84.3 E(32554): 4.6e-17 Smith-Waterman score: 542; 71.5% identity (91.1% similar) in 123 aa overlap (48-170:4-126) 20 30 40 50 60 70 pF1KB5 LFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKCTSGQSFEVILKPPSFDGVP ::..: ::.: .:::.::.::.: : ..:: CCDS44 MASSDIQVKELEKRASGQAFELILSPRSKESVP 10 20 30 80 90 100 110 120 130 pF1KB5 EFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNF :: : :...: ::::::::::::::::: .:::.::.::::::::.::.:::::::::: CCDS44 EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNF 40 50 60 70 80 90 140 150 160 170 180 pF1KB5 IKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVRKNKELKEEASR :::.:::..:::.:::::::..:: ::::.:: CCDS44 SKMAEEKLTHKMEANKENREAQMAAKLERLREKMYFWTHGPGAHPAQISAEQSCLHSVPA 100 110 120 130 140 150 CCDS44 LCPALGLQSALITWSDLSHHH 160 170 >>CCDS56542.1 STMN2 gene_id:11075|Hs108|chr8 (187 aa) initn: 625 init1: 518 opt: 529 Z-score: 410.0 bits: 82.6 E(32554): 1.6e-16 Smith-Waterman score: 626; 63.5% identity (80.0% similar) in 170 aa overlap (2-170:4-160) 10 20 30 40 50 pF1KB5 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKC : ::::::::: ..::.:::: .: : . : :. :::: ..:: CCDS56 MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYD------------DMEVKQINKR 10 20 30 40 60 70 80 90 100 110 pF1KB5 TSGQSFEVILKPPS-FDGVPEFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLA .:::.::.:::::: .. .:. :: :...: ::::::::::::::::: :::..::.:: CCDS56 ASGQAFELILKPPSPISEAPRTLAS-PKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLA 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB5 EKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEV :::::::::.:::.:::::: :::.::: :::. ::::::.:::..:::::: CCDS56 EKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKLVKFISS 110 120 130 140 150 160 180 pF1KB5 RKNKELKEEASR CCDS56 ELKESIESQFLELQREGEKQ 170 180 189 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 12:24:07 2016 done: Sat Nov 5 12:24:08 2016 Total Scan time: 2.270 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]