Result of FASTA (omim) for
pF1KB5288
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5288, 550 aa
1>>>pF1KB5288 550 - 550 aa - 550 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.7590+/-0.000356; mu= 7.8478+/- 0.022
mean_var=162.4205+/-33.641, 0's: 0 Z-trim(119.6): 18 B-trim: 752 in 1/58
Lambda= 0.100636
statistics sampled from 33746 (33764) to 33746 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.744), E-opt: 0.2 (0.396), width: 16
Scan time: 11.600
The best scores are: opt bits E(85289)
NP_149035 (OMIM: 602288) rhotekin isoform b [Homo ( 550) 3761 558.2 2.4e-158
XP_016860124 (OMIM: 602288) PREDICTED: rhotekin is ( 550) 3761 558.2 2.4e-158
NP_001015055 (OMIM: 602288) rhotekin isoform a [Ho ( 563) 3615 537.0 5.9e-152
NP_001015056 (OMIM: 602288) rhotekin isoform c [Ho ( 513) 3524 523.7 5.2e-148
XP_016860127 (OMIM: 602288) PREDICTED: rhotekin is ( 433) 2989 446.0 1.1e-124
XP_016860125 (OMIM: 602288) PREDICTED: rhotekin is ( 477) 2969 443.1 8.9e-124
XP_005264535 (OMIM: 602288) PREDICTED: rhotekin is ( 490) 2823 422.0 2.2e-117
XP_005264536 (OMIM: 602288) PREDICTED: rhotekin is ( 465) 2817 421.1 3.8e-117
XP_016860126 (OMIM: 602288) PREDICTED: rhotekin is ( 440) 2732 408.7 1.9e-113
XP_016860128 (OMIM: 602288) PREDICTED: rhotekin is ( 415) 2726 407.8 3.3e-113
XP_016860129 (OMIM: 602288) PREDICTED: rhotekin is ( 360) 2197 331.0 3.9e-90
>>NP_149035 (OMIM: 602288) rhotekin isoform b [Homo sapi (550 aa)
initn: 3761 init1: 3761 opt: 3761 Z-score: 2963.7 bits: 558.2 E(85289): 2.4e-158
Smith-Waterman score: 3761; 100.0% identity (100.0% similar) in 550 aa overlap (1-550:1-550)
10 20 30 40 50 60
pF1KB5 MQDRLHILEDLNMLYIRQMALSLEDTELQRKLDHEIRMREGACKLLAACSQREQALEATK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 MQDRLHILEDLNMLYIRQMALSLEDTELQRKLDHEIRMREGACKLLAACSQREQALEATK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SLLVCNSRILSYMGELQRRKEAQVLGKTSRRPSDSGPPAERSPCRGRVCISDLRIPLMWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SLLVCNSRILSYMGELQRRKEAQVLGKTSRRPSDSGPPAERSPCRGRVCISDLRIPLMWK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 DTEYFKNKGDLHRWAVFLLLQLGEHIQDTEMILVDRTLTDISFQSNVLFAEAGPDFELRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 DTEYFKNKGDLHRWAVFLLLQLGEHIQDTEMILVDRTLTDISFQSNVLFAEAGPDFELRL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 ELYGACVEEEGALTGGPKRLATKLSSSLGRSSGRRVRASLDSAGGSGSSPILLPTPVVGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 ELYGACVEEEGALTGGPKRLATKLSSSLGRSSGRRVRASLDSAGGSGSSPILLPTPVVGG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PRYHLLAHTTLTLAAVQDGFRTHDLTLASHEENPAWLPLYGSVCCRLAAQPLCMTQPTAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 PRYHLLAHTTLTLAAVQDGFRTHDLTLASHEENPAWLPLYGSVCCRLAAQPLCMTQPTAS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 GTLRVQQAGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEEPLLTIAVNKETRVRAGELDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 GTLRVQQAGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEEPLLTIAVNKETRVRAGELDQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 ALGRPFTLSISNQYGDDEVTHTLQTESREALQSWMEALWQLFFDMSQWKQCCDEIMKIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 ALGRPFTLSISNQYGDDEVTHTLQTESREALQSWMEALWQLFFDMSQWKQCCDEIMKIET
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 PAPRKPPQALAKQGSLYHEMAIEPLDDIAAVTDILTQREGARLETPPPWLAMFTDQPALP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 PAPRKPPQALAKQGSLYHEMAIEPLDDIAAVTDILTQREGARLETPPPWLAMFTDQPALP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 NPCSPASVAPAPDWTHPLPWGRPRTFSLDAVPPDHSPRARSVAPLPPQRSPRTRGLCSKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 NPCSPASVAPAPDWTHPLPWGRPRTFSLDAVPPDHSPRARSVAPLPPQRSPRTRGLCSKG
490 500 510 520 530 540
550
pF1KB5 QPRTWLQSPV
::::::::::
NP_149 QPRTWLQSPV
550
>>XP_016860124 (OMIM: 602288) PREDICTED: rhotekin isofor (550 aa)
initn: 3761 init1: 3761 opt: 3761 Z-score: 2963.7 bits: 558.2 E(85289): 2.4e-158
Smith-Waterman score: 3761; 100.0% identity (100.0% similar) in 550 aa overlap (1-550:1-550)
10 20 30 40 50 60
pF1KB5 MQDRLHILEDLNMLYIRQMALSLEDTELQRKLDHEIRMREGACKLLAACSQREQALEATK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQDRLHILEDLNMLYIRQMALSLEDTELQRKLDHEIRMREGACKLLAACSQREQALEATK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SLLVCNSRILSYMGELQRRKEAQVLGKTSRRPSDSGPPAERSPCRGRVCISDLRIPLMWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLVCNSRILSYMGELQRRKEAQVLGKTSRRPSDSGPPAERSPCRGRVCISDLRIPLMWK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 DTEYFKNKGDLHRWAVFLLLQLGEHIQDTEMILVDRTLTDISFQSNVLFAEAGPDFELRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTEYFKNKGDLHRWAVFLLLQLGEHIQDTEMILVDRTLTDISFQSNVLFAEAGPDFELRL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 ELYGACVEEEGALTGGPKRLATKLSSSLGRSSGRRVRASLDSAGGSGSSPILLPTPVVGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELYGACVEEEGALTGGPKRLATKLSSSLGRSSGRRVRASLDSAGGSGSSPILLPTPVVGG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PRYHLLAHTTLTLAAVQDGFRTHDLTLASHEENPAWLPLYGSVCCRLAAQPLCMTQPTAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRYHLLAHTTLTLAAVQDGFRTHDLTLASHEENPAWLPLYGSVCCRLAAQPLCMTQPTAS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 GTLRVQQAGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEEPLLTIAVNKETRVRAGELDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTLRVQQAGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEEPLLTIAVNKETRVRAGELDQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 ALGRPFTLSISNQYGDDEVTHTLQTESREALQSWMEALWQLFFDMSQWKQCCDEIMKIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALGRPFTLSISNQYGDDEVTHTLQTESREALQSWMEALWQLFFDMSQWKQCCDEIMKIET
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 PAPRKPPQALAKQGSLYHEMAIEPLDDIAAVTDILTQREGARLETPPPWLAMFTDQPALP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAPRKPPQALAKQGSLYHEMAIEPLDDIAAVTDILTQREGARLETPPPWLAMFTDQPALP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 NPCSPASVAPAPDWTHPLPWGRPRTFSLDAVPPDHSPRARSVAPLPPQRSPRTRGLCSKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPCSPASVAPAPDWTHPLPWGRPRTFSLDAVPPDHSPRARSVAPLPPQRSPRTRGLCSKG
490 500 510 520 530 540
550
pF1KB5 QPRTWLQSPV
::::::::::
XP_016 QPRTWLQSPV
550
>>NP_001015055 (OMIM: 602288) rhotekin isoform a [Homo s (563 aa)
initn: 3615 init1: 3615 opt: 3615 Z-score: 2849.0 bits: 537.0 E(85289): 5.9e-152
Smith-Waterman score: 3615; 100.0% identity (100.0% similar) in 527 aa overlap (24-550:37-563)
10 20 30 40 50
pF1KB5 MQDRLHILEDLNMLYIRQMALSLEDTELQRKLDHEIRMREGACKLLAACSQRE
::::::::::::::::::::::::::::::
NP_001 RSRVTVARGSALEMEFKRGRFRLSLFSDLPEDTELQRKLDHEIRMREGACKLLAACSQRE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 QALEATKSLLVCNSRILSYMGELQRRKEAQVLGKTSRRPSDSGPPAERSPCRGRVCISDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QALEATKSLLVCNSRILSYMGELQRRKEAQVLGKTSRRPSDSGPPAERSPCRGRVCISDL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 RIPLMWKDTEYFKNKGDLHRWAVFLLLQLGEHIQDTEMILVDRTLTDISFQSNVLFAEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIPLMWKDTEYFKNKGDLHRWAVFLLLQLGEHIQDTEMILVDRTLTDISFQSNVLFAEAG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 PDFELRLELYGACVEEEGALTGGPKRLATKLSSSLGRSSGRRVRASLDSAGGSGSSPILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDFELRLELYGACVEEEGALTGGPKRLATKLSSSLGRSSGRRVRASLDSAGGSGSSPILL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 PTPVVGGPRYHLLAHTTLTLAAVQDGFRTHDLTLASHEENPAWLPLYGSVCCRLAAQPLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTPVVGGPRYHLLAHTTLTLAAVQDGFRTHDLTLASHEENPAWLPLYGSVCCRLAAQPLC
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 MTQPTASGTLRVQQAGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEEPLLTIAVNKETRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTQPTASGTLRVQQAGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEEPLLTIAVNKETRV
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 RAGELDQALGRPFTLSISNQYGDDEVTHTLQTESREALQSWMEALWQLFFDMSQWKQCCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAGELDQALGRPFTLSISNQYGDDEVTHTLQTESREALQSWMEALWQLFFDMSQWKQCCD
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB5 EIMKIETPAPRKPPQALAKQGSLYHEMAIEPLDDIAAVTDILTQREGARLETPPPWLAMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIMKIETPAPRKPPQALAKQGSLYHEMAIEPLDDIAAVTDILTQREGARLETPPPWLAMF
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB5 TDQPALPNPCSPASVAPAPDWTHPLPWGRPRTFSLDAVPPDHSPRARSVAPLPPQRSPRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDQPALPNPCSPASVAPAPDWTHPLPWGRPRTFSLDAVPPDHSPRARSVAPLPPQRSPRT
490 500 510 520 530 540
540 550
pF1KB5 RGLCSKGQPRTWLQSPV
:::::::::::::::::
NP_001 RGLCSKGQPRTWLQSPV
550 560
>>NP_001015056 (OMIM: 602288) rhotekin isoform c [Homo s (513 aa)
initn: 3524 init1: 3524 opt: 3524 Z-score: 2778.2 bits: 523.7 E(85289): 5.2e-148
Smith-Waterman score: 3524; 100.0% identity (100.0% similar) in 513 aa overlap (38-550:1-513)
10 20 30 40 50 60
pF1KB5 LEDLNMLYIRQMALSLEDTELQRKLDHEIRMREGACKLLAACSQREQALEATKSLLVCNS
::::::::::::::::::::::::::::::
NP_001 MREGACKLLAACSQREQALEATKSLLVCNS
10 20 30
70 80 90 100 110 120
pF1KB5 RILSYMGELQRRKEAQVLGKTSRRPSDSGPPAERSPCRGRVCISDLRIPLMWKDTEYFKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RILSYMGELQRRKEAQVLGKTSRRPSDSGPPAERSPCRGRVCISDLRIPLMWKDTEYFKN
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 KGDLHRWAVFLLLQLGEHIQDTEMILVDRTLTDISFQSNVLFAEAGPDFELRLELYGACV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGDLHRWAVFLLLQLGEHIQDTEMILVDRTLTDISFQSNVLFAEAGPDFELRLELYGACV
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 EEEGALTGGPKRLATKLSSSLGRSSGRRVRASLDSAGGSGSSPILLPTPVVGGPRYHLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEGALTGGPKRLATKLSSSLGRSSGRRVRASLDSAGGSGSSPILLPTPVVGGPRYHLLA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 HTTLTLAAVQDGFRTHDLTLASHEENPAWLPLYGSVCCRLAAQPLCMTQPTASGTLRVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTTLTLAAVQDGFRTHDLTLASHEENPAWLPLYGSVCCRLAAQPLCMTQPTASGTLRVQQ
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 AGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEEPLLTIAVNKETRVRAGELDQALGRPFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEEPLLTIAVNKETRVRAGELDQALGRPFT
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 LSISNQYGDDEVTHTLQTESREALQSWMEALWQLFFDMSQWKQCCDEIMKIETPAPRKPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSISNQYGDDEVTHTLQTESREALQSWMEALWQLFFDMSQWKQCCDEIMKIETPAPRKPP
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB5 QALAKQGSLYHEMAIEPLDDIAAVTDILTQREGARLETPPPWLAMFTDQPALPNPCSPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QALAKQGSLYHEMAIEPLDDIAAVTDILTQREGARLETPPPWLAMFTDQPALPNPCSPAS
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB5 VAPAPDWTHPLPWGRPRTFSLDAVPPDHSPRARSVAPLPPQRSPRTRGLCSKGQPRTWLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAPAPDWTHPLPWGRPRTFSLDAVPPDHSPRARSVAPLPPQRSPRTRGLCSKGQPRTWLQ
460 470 480 490 500 510
550
pF1KB5 SPV
:::
NP_001 SPV
>>XP_016860127 (OMIM: 602288) PREDICTED: rhotekin isofor (433 aa)
initn: 2989 init1: 2989 opt: 2989 Z-score: 2359.4 bits: 446.0 E(85289): 1.1e-124
Smith-Waterman score: 2989; 100.0% identity (100.0% similar) in 433 aa overlap (118-550:1-433)
90 100 110 120 130 140
pF1KB5 TSRRPSDSGPPAERSPCRGRVCISDLRIPLMWKDTEYFKNKGDLHRWAVFLLLQLGEHIQ
::::::::::::::::::::::::::::::
XP_016 MWKDTEYFKNKGDLHRWAVFLLLQLGEHIQ
10 20 30
150 160 170 180 190 200
pF1KB5 DTEMILVDRTLTDISFQSNVLFAEAGPDFELRLELYGACVEEEGALTGGPKRLATKLSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTEMILVDRTLTDISFQSNVLFAEAGPDFELRLELYGACVEEEGALTGGPKRLATKLSSS
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB5 LGRSSGRRVRASLDSAGGSGSSPILLPTPVVGGPRYHLLAHTTLTLAAVQDGFRTHDLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGRSSGRRVRASLDSAGGSGSSPILLPTPVVGGPRYHLLAHTTLTLAAVQDGFRTHDLTL
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB5 ASHEENPAWLPLYGSVCCRLAAQPLCMTQPTASGTLRVQQAGEMQNWAQVHGVLKGTNLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASHEENPAWLPLYGSVCCRLAAQPLCMTQPTASGTLRVQQAGEMQNWAQVHGVLKGTNLF
160 170 180 190 200 210
330 340 350 360 370 380
pF1KB5 CYRQPEDADTGEEPLLTIAVNKETRVRAGELDQALGRPFTLSISNQYGDDEVTHTLQTES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CYRQPEDADTGEEPLLTIAVNKETRVRAGELDQALGRPFTLSISNQYGDDEVTHTLQTES
220 230 240 250 260 270
390 400 410 420 430 440
pF1KB5 REALQSWMEALWQLFFDMSQWKQCCDEIMKIETPAPRKPPQALAKQGSLYHEMAIEPLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REALQSWMEALWQLFFDMSQWKQCCDEIMKIETPAPRKPPQALAKQGSLYHEMAIEPLDD
280 290 300 310 320 330
450 460 470 480 490 500
pF1KB5 IAAVTDILTQREGARLETPPPWLAMFTDQPALPNPCSPASVAPAPDWTHPLPWGRPRTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAAVTDILTQREGARLETPPPWLAMFTDQPALPNPCSPASVAPAPDWTHPLPWGRPRTFS
340 350 360 370 380 390
510 520 530 540 550
pF1KB5 LDAVPPDHSPRARSVAPLPPQRSPRTRGLCSKGQPRTWLQSPV
:::::::::::::::::::::::::::::::::::::::::::
XP_016 LDAVPPDHSPRARSVAPLPPQRSPRTRGLCSKGQPRTWLQSPV
400 410 420 430
>>XP_016860125 (OMIM: 602288) PREDICTED: rhotekin isofor (477 aa)
initn: 2960 init1: 2960 opt: 2969 Z-score: 2343.2 bits: 443.1 E(85289): 8.9e-124
Smith-Waterman score: 2969; 93.5% identity (96.0% similar) in 477 aa overlap (1-476:1-477)
10 20 30 40 50 60
pF1KB5 MQDRLHILEDLNMLYIRQMALSLEDTELQRKLDHEIRMREGACKLLAACSQREQALEATK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQDRLHILEDLNMLYIRQMALSLEDTELQRKLDHEIRMREGACKLLAACSQREQALEATK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SLLVCNSRILSYMGELQRRKEAQVLGKTSRRPSDSGPPAERSPCRGRVCISDLRIPLMWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLVCNSRILSYMGELQRRKEAQVLGKTSRRPSDSGPPAERSPCRGRVCISDLRIPLMWK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 DTEYFKNKGDLHRWAVFLLLQLGEHIQDTEMILVDRTLTDISFQSNVLFAEAGPDFELRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTEYFKNKGDLHRWAVFLLLQLGEHIQDTEMILVDRTLTDISFQSNVLFAEAGPDFELRL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 ELYGACVEEEGALTGGPKRLATKLSSSLGRSSGRRVRASLDSAGGSGSSPILLPTPVVGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELYGACVEEEGALTGGPKRLATKLSSSLGRSSGRRVRASLDSAGGSGSSPILLPTPVVGG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PRYHLLAHTTLTLAAVQDGFRTHDLTLASHEENPAWLPLYGSVCCRLAAQPLCMTQPTAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRYHLLAHTTLTLAAVQDGFRTHDLTLASHEENPAWLPLYGSVCCRLAAQPLCMTQPTAS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 GTLRVQQAGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEEPLLTIAVNKETRVRAGELDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTLRVQQAGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEEPLLTIAVNKETRVRAGELDQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 ALGRPFTLSISNQYGDDEVTHTLQTESREALQSWMEALWQLFFDMSQWKQCCDEIMKIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALGRPFTLSISNQYGDDEVTHTLQTESREALQSWMEALWQLFFDMSQWKQCCDEIMKIET
370 380 390 400 410 420
430 440 450 460 470
pF1KB5 PAPRKPPQALAKQGSLYHEMAI-EPLDDIAAVTDILTQREGARLETPPPWLAMFTDQPAL
::::::::::::::::::::.. ::. . .: : .. : ....:.
XP_016 PAPRKPPQALAKQGSLYHEMVLSEPVAPGGPGEGLLLQDNAISTEIQALLSSYYSDR
430 440 450 460 470
480 490 500 510 520 530
pF1KB5 PNPCSPASVAPAPDWTHPLPWGRPRTFSLDAVPPDHSPRARSVAPLPPQRSPRTRGLCSK
>>XP_005264535 (OMIM: 602288) PREDICTED: rhotekin isofor (490 aa)
initn: 2838 init1: 2814 opt: 2823 Z-score: 2228.4 bits: 422.0 E(85289): 2.2e-117
Smith-Waterman score: 2823; 93.2% identity (95.8% similar) in 454 aa overlap (24-476:37-490)
10 20 30 40 50
pF1KB5 MQDRLHILEDLNMLYIRQMALSLEDTELQRKLDHEIRMREGACKLLAACSQRE
::::::::::::::::::::::::::::::
XP_005 RSRVTVARGSALEMEFKRGRFRLSLFSDLPEDTELQRKLDHEIRMREGACKLLAACSQRE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 QALEATKSLLVCNSRILSYMGELQRRKEAQVLGKTSRRPSDSGPPAERSPCRGRVCISDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QALEATKSLLVCNSRILSYMGELQRRKEAQVLGKTSRRPSDSGPPAERSPCRGRVCISDL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 RIPLMWKDTEYFKNKGDLHRWAVFLLLQLGEHIQDTEMILVDRTLTDISFQSNVLFAEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RIPLMWKDTEYFKNKGDLHRWAVFLLLQLGEHIQDTEMILVDRTLTDISFQSNVLFAEAG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 PDFELRLELYGACVEEEGALTGGPKRLATKLSSSLGRSSGRRVRASLDSAGGSGSSPILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDFELRLELYGACVEEEGALTGGPKRLATKLSSSLGRSSGRRVRASLDSAGGSGSSPILL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 PTPVVGGPRYHLLAHTTLTLAAVQDGFRTHDLTLASHEENPAWLPLYGSVCCRLAAQPLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTPVVGGPRYHLLAHTTLTLAAVQDGFRTHDLTLASHEENPAWLPLYGSVCCRLAAQPLC
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 MTQPTASGTLRVQQAGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEEPLLTIAVNKETRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTQPTASGTLRVQQAGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEEPLLTIAVNKETRV
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 RAGELDQALGRPFTLSISNQYGDDEVTHTLQTESREALQSWMEALWQLFFDMSQWKQCCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RAGELDQALGRPFTLSISNQYGDDEVTHTLQTESREALQSWMEALWQLFFDMSQWKQCCD
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB5 EIMKIETPAPRKPPQALAKQGSLYHEMAI-EPLDDIAAVTDILTQREGARLETPPPWLAM
:::::::::::::::::::::::::::.. ::. . .: : .. : ..
XP_005 EIMKIETPAPRKPPQALAKQGSLYHEMVLSEPVAPGGPGEGLLLQDNAISTEIQALLSSY
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB5 FTDQPALPNPCSPASVAPAPDWTHPLPWGRPRTFSLDAVPPDHSPRARSVAPLPPQRSPR
..:.
XP_005 YSDR
490
>>XP_005264536 (OMIM: 602288) PREDICTED: rhotekin isofor (465 aa)
initn: 2812 init1: 2812 opt: 2817 Z-score: 2224.1 bits: 421.1 E(85289): 3.8e-117
Smith-Waterman score: 2817; 99.3% identity (99.3% similar) in 421 aa overlap (24-444:37-457)
10 20 30 40 50
pF1KB5 MQDRLHILEDLNMLYIRQMALSLEDTELQRKLDHEIRMREGACKLLAACSQRE
::::::::::::::::::::::::::::::
XP_005 RSRVTVARGSALEMEFKRGRFRLSLFSDLPEDTELQRKLDHEIRMREGACKLLAACSQRE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 QALEATKSLLVCNSRILSYMGELQRRKEAQVLGKTSRRPSDSGPPAERSPCRGRVCISDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QALEATKSLLVCNSRILSYMGELQRRKEAQVLGKTSRRPSDSGPPAERSPCRGRVCISDL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 RIPLMWKDTEYFKNKGDLHRWAVFLLLQLGEHIQDTEMILVDRTLTDISFQSNVLFAEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RIPLMWKDTEYFKNKGDLHRWAVFLLLQLGEHIQDTEMILVDRTLTDISFQSNVLFAEAG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 PDFELRLELYGACVEEEGALTGGPKRLATKLSSSLGRSSGRRVRASLDSAGGSGSSPILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDFELRLELYGACVEEEGALTGGPKRLATKLSSSLGRSSGRRVRASLDSAGGSGSSPILL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 PTPVVGGPRYHLLAHTTLTLAAVQDGFRTHDLTLASHEENPAWLPLYGSVCCRLAAQPLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTPVVGGPRYHLLAHTTLTLAAVQDGFRTHDLTLASHEENPAWLPLYGSVCCRLAAQPLC
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 MTQPTASGTLRVQQAGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEEPLLTIAVNKETRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTQPTASGTLRVQQAGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEEPLLTIAVNKETRV
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 RAGELDQALGRPFTLSISNQYGDDEVTHTLQTESREALQSWMEALWQLFFDMSQWKQCCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RAGELDQALGRPFTLSISNQYGDDEVTHTLQTESREALQSWMEALWQLFFDMSQWKQCCD
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB5 EIMKIETPAPRKPPQALAKQGSLYHEMAIEPLDDIAAVTDILTQREGARLETPPPWLAMF
::::::::::::::::::::::::::: :
XP_005 EIMKIETPAPRKPPQALAKQGSLYHEMEPPPPKFKTKPQ
430 440 450 460
480 490 500 510 520 530
pF1KB5 TDQPALPNPCSPASVAPAPDWTHPLPWGRPRTFSLDAVPPDHSPRARSVAPLPPQRSPRT
>>XP_016860126 (OMIM: 602288) PREDICTED: rhotekin isofor (440 aa)
initn: 2723 init1: 2723 opt: 2732 Z-score: 2157.7 bits: 408.7 E(85289): 1.9e-113
Smith-Waterman score: 2732; 93.0% identity (95.7% similar) in 440 aa overlap (38-476:1-440)
10 20 30 40 50 60
pF1KB5 LEDLNMLYIRQMALSLEDTELQRKLDHEIRMREGACKLLAACSQREQALEATKSLLVCNS
::::::::::::::::::::::::::::::
XP_016 MREGACKLLAACSQREQALEATKSLLVCNS
10 20 30
70 80 90 100 110 120
pF1KB5 RILSYMGELQRRKEAQVLGKTSRRPSDSGPPAERSPCRGRVCISDLRIPLMWKDTEYFKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RILSYMGELQRRKEAQVLGKTSRRPSDSGPPAERSPCRGRVCISDLRIPLMWKDTEYFKN
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 KGDLHRWAVFLLLQLGEHIQDTEMILVDRTLTDISFQSNVLFAEAGPDFELRLELYGACV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGDLHRWAVFLLLQLGEHIQDTEMILVDRTLTDISFQSNVLFAEAGPDFELRLELYGACV
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 EEEGALTGGPKRLATKLSSSLGRSSGRRVRASLDSAGGSGSSPILLPTPVVGGPRYHLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEGALTGGPKRLATKLSSSLGRSSGRRVRASLDSAGGSGSSPILLPTPVVGGPRYHLLA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 HTTLTLAAVQDGFRTHDLTLASHEENPAWLPLYGSVCCRLAAQPLCMTQPTASGTLRVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTTLTLAAVQDGFRTHDLTLASHEENPAWLPLYGSVCCRLAAQPLCMTQPTASGTLRVQQ
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 AGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEEPLLTIAVNKETRVRAGELDQALGRPFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEEPLLTIAVNKETRVRAGELDQALGRPFT
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 LSISNQYGDDEVTHTLQTESREALQSWMEALWQLFFDMSQWKQCCDEIMKIETPAPRKPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSISNQYGDDEVTHTLQTESREALQSWMEALWQLFFDMSQWKQCCDEIMKIETPAPRKPP
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB5 QALAKQGSLYHEMAI-EPLDDIAAVTDILTQREGARLETPPPWLAMFTDQPALPNPCSPA
:::::::::::::.. ::. . .: : .. : ....:.
XP_016 QALAKQGSLYHEMVLSEPVAPGGPGEGLLLQDNAISTEIQALLSSYYSDR
400 410 420 430 440
490 500 510 520 530 540
pF1KB5 SVAPAPDWTHPLPWGRPRTFSLDAVPPDHSPRARSVAPLPPQRSPRTRGLCSKGQPRTWL
>>XP_016860128 (OMIM: 602288) PREDICTED: rhotekin isofor (415 aa)
initn: 2721 init1: 2721 opt: 2726 Z-score: 2153.3 bits: 407.8 E(85289): 3.3e-113
Smith-Waterman score: 2726; 99.3% identity (99.3% similar) in 407 aa overlap (38-444:1-407)
10 20 30 40 50 60
pF1KB5 LEDLNMLYIRQMALSLEDTELQRKLDHEIRMREGACKLLAACSQREQALEATKSLLVCNS
::::::::::::::::::::::::::::::
XP_016 MREGACKLLAACSQREQALEATKSLLVCNS
10 20 30
70 80 90 100 110 120
pF1KB5 RILSYMGELQRRKEAQVLGKTSRRPSDSGPPAERSPCRGRVCISDLRIPLMWKDTEYFKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RILSYMGELQRRKEAQVLGKTSRRPSDSGPPAERSPCRGRVCISDLRIPLMWKDTEYFKN
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 KGDLHRWAVFLLLQLGEHIQDTEMILVDRTLTDISFQSNVLFAEAGPDFELRLELYGACV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGDLHRWAVFLLLQLGEHIQDTEMILVDRTLTDISFQSNVLFAEAGPDFELRLELYGACV
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 EEEGALTGGPKRLATKLSSSLGRSSGRRVRASLDSAGGSGSSPILLPTPVVGGPRYHLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEGALTGGPKRLATKLSSSLGRSSGRRVRASLDSAGGSGSSPILLPTPVVGGPRYHLLA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 HTTLTLAAVQDGFRTHDLTLASHEENPAWLPLYGSVCCRLAAQPLCMTQPTASGTLRVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTTLTLAAVQDGFRTHDLTLASHEENPAWLPLYGSVCCRLAAQPLCMTQPTASGTLRVQQ
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 AGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEEPLLTIAVNKETRVRAGELDQALGRPFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEEPLLTIAVNKETRVRAGELDQALGRPFT
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 LSISNQYGDDEVTHTLQTESREALQSWMEALWQLFFDMSQWKQCCDEIMKIETPAPRKPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSISNQYGDDEVTHTLQTESREALQSWMEALWQLFFDMSQWKQCCDEIMKIETPAPRKPP
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB5 QALAKQGSLYHEMAIEPLDDIAAVTDILTQREGARLETPPPWLAMFTDQPALPNPCSPAS
::::::::::::: :
XP_016 QALAKQGSLYHEMEPPPPKFKTKPQ
400 410
550 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 22:08:57 2016 done: Fri Nov 4 22:08:58 2016
Total Scan time: 11.600 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]