FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5300, 417 aa 1>>>pF1KB5300 417 - 417 aa - 417 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2022+/-0.000408; mu= 17.4963+/- 0.025 mean_var=65.1496+/-13.033, 0's: 0 Z-trim(110.5): 18 B-trim: 76 in 1/50 Lambda= 0.158898 statistics sampled from 18805 (18812) to 18805 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.594), E-opt: 0.2 (0.221), width: 16 Scan time: 7.980 The best scores are: opt bits E(85289) NP_000282 (OMIM: 300653,311800) phosphoglycerate k ( 417) 2717 632.1 8e-181 NP_620061 (OMIM: 172270) phosphoglycerate kinase 2 ( 417) 2459 572.9 5.1e-163 >>NP_000282 (OMIM: 300653,311800) phosphoglycerate kinas (417 aa) initn: 2717 init1: 2717 opt: 2717 Z-score: 3367.4 bits: 632.1 E(85289): 8e-181 Smith-Waterman score: 2717; 100.0% identity (100.0% similar) in 417 aa overlap (1-417:1-417) 10 20 30 40 50 60 pF1KB5 MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 NLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 AFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 ATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 ATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVV 310 320 330 340 350 360 370 380 390 400 410 pF1KB5 KATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI 370 380 390 400 410 >>NP_620061 (OMIM: 172270) phosphoglycerate kinase 2 [Ho (417 aa) initn: 2521 init1: 2459 opt: 2459 Z-score: 3047.7 bits: 572.9 E(85289): 5.1e-163 Smith-Waterman score: 2459; 87.3% identity (97.8% similar) in 417 aa overlap (1-417:1-417) 10 20 30 40 50 60 pF1KB5 MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVL ::::.:::::::::.::::.::::::::::.:::::::::::..::::.:::::::.::: NP_620 MSLSKKLTLDKLDVRGKRVIMRVDFNVPMKKNQITNNQRIKASIPSIKYCLDNGAKAVVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLE :::::::::::::::::: :::::::::::::::::::::: :::::::::: ::::::: NP_620 MSHLGRPDGVPMPDKYSLAPVAVELKSLLGKDVLFLKDCVGAEVEKACANPAPGSVILLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN ::::::::::::.: ::.:.:::: ::::::::::::::::::::::::::::::::::: NP_620 NLRFHVEEEGKGQDPSGKKIKAEPDKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGM ::.::.::::::::.:::::::.: :::::::::::::::::::.::::::::::::::: NP_620 LPHKASGFLMKKELDYFAKALENPVRPFLAILGGAKVADKIQLIKNMLDKVNEMIIGGGM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQ :.::::::::::::.:::::::::::::.:.::.::::.::.::::::.:::::::..:. NP_620 AYTFLKVLNNMEIGASLFDEEGAKIVKDIMAKAQKNGVRITFPVDFVTGDKFDENAQVGK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 ATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVV ::::::: :::::::::::.:..:..:..:. ::::::.:::::.:::.::::::::.: NP_620 ATVASGISPGWMGLDCGPESNKNHAQVVAQARLIVWNGPLGVFEWDAFAKGTKALMDEIV 310 320 330 340 350 360 370 380 390 400 410 pF1KB5 KATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI ::::.::::.::::::::::::::::::::::::::::::::::::.::::.::::. NP_620 KATSKGCITVIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKILPGVEALSNM 370 380 390 400 410 417 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:27:46 2016 done: Thu Nov 3 22:27:47 2016 Total Scan time: 7.980 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]