FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5302, 309 aa 1>>>pF1KB5302 309 - 309 aa - 309 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2251+/-0.000354; mu= 16.0973+/- 0.022 mean_var=61.9292+/-12.197, 0's: 0 Z-trim(114.1): 49 B-trim: 170 in 1/52 Lambda= 0.162977 statistics sampled from 23670 (23721) to 23670 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.278), width: 16 Scan time: 6.740 The best scores are: opt bits E(85289) NP_002706 (OMIM: 176915) serine/threonine-protein ( 309) 2157 515.6 5.1e-146 NP_001009552 (OMIM: 176916) serine/threonine-prote ( 309) 2123 507.6 1.3e-143 NP_001290432 (OMIM: 602035) serine/threonine-prote ( 307) 1465 352.9 4.9e-97 NP_002711 (OMIM: 602035) serine/threonine-protein ( 307) 1465 352.9 4.9e-97 NP_002712 (OMIM: 612725) serine/threonine-protein ( 305) 1241 300.2 3.5e-81 XP_011517149 (OMIM: 612725) PREDICTED: serine/thre ( 293) 1186 287.2 2.6e-77 NP_001116827 (OMIM: 612725) serine/threonine-prote ( 342) 1186 287.3 3e-77 XP_016878893 (OMIM: 602035) PREDICTED: serine/thre ( 228) 1117 271.0 1.6e-72 XP_016878892 (OMIM: 602035) PREDICTED: serine/thre ( 228) 1117 271.0 1.6e-72 NP_001290435 (OMIM: 602035) serine/threonine-prote ( 228) 1117 271.0 1.6e-72 NP_001290436 (OMIM: 602035) serine/threonine-prote ( 228) 1117 271.0 1.6e-72 NP_001290433 (OMIM: 602035) serine/threonine-prote ( 273) 1008 245.4 9.8e-65 XP_006721124 (OMIM: 602035) PREDICTED: serine/thre ( 273) 1008 245.4 9.8e-65 NP_002701 (OMIM: 176914) serine/threonine-protein ( 323) 1002 244.0 3e-64 XP_011536807 (OMIM: 176914) PREDICTED: serine/thre ( 330) 1002 244.0 3.1e-64 NP_001231903 (OMIM: 176914) serine/threonine-prote ( 337) 1002 244.0 3.1e-64 XP_011536806 (OMIM: 176914) PREDICTED: serine/thre ( 362) 1002 244.0 3.3e-64 NP_002699 (OMIM: 176875) serine/threonine-protein ( 330) 991 241.4 1.8e-63 NP_001008709 (OMIM: 176875) serine/threonine-prote ( 341) 991 241.4 1.9e-63 NP_996759 (OMIM: 600590) serine/threonine-protein ( 327) 967 235.8 9.1e-62 NP_002700 (OMIM: 600590) serine/threonine-protein ( 327) 967 235.8 9.1e-62 NP_001116841 (OMIM: 612725) serine/threonine-prote ( 283) 930 227.0 3.4e-59 NP_996756 (OMIM: 176875) serine/threonine-protein ( 286) 895 218.8 1e-56 NP_006238 (OMIM: 600658) serine/threonine-protein ( 499) 783 192.6 1.4e-48 XP_016882424 (OMIM: 600658) PREDICTED: serine/thre ( 551) 775 190.7 5.5e-48 NP_001191213 (OMIM: 600658) serine/threonine-prote ( 477) 739 182.2 1.7e-45 NP_001124164 (OMIM: 114105) serine/threonine-prote ( 469) 697 172.4 1.6e-42 XP_016863854 (OMIM: 114105) PREDICTED: serine/thre ( 509) 697 172.4 1.7e-42 NP_001124163 (OMIM: 114105) serine/threonine-prote ( 511) 697 172.4 1.7e-42 NP_000935 (OMIM: 114105) serine/threonine-protein ( 521) 697 172.4 1.8e-42 XP_016871868 (OMIM: 114106) PREDICTED: serine/thre ( 426) 677 167.6 3.8e-41 XP_005270001 (OMIM: 114106) PREDICTED: serine/thre ( 514) 677 167.7 4.5e-41 NP_001135826 (OMIM: 114106) serine/threonine-prote ( 515) 677 167.7 4.5e-41 NP_066955 (OMIM: 114106) serine/threonine-protein ( 524) 677 167.7 4.6e-41 NP_001135825 (OMIM: 114106) serine/threonine-prote ( 525) 677 167.7 4.6e-41 NP_001276898 (OMIM: 114106) serine/threonine-prote ( 410) 661 163.9 5e-40 XP_016869100 (OMIM: 114107) PREDICTED: serine/thre ( 418) 661 163.9 5.1e-40 NP_001230904 (OMIM: 114107) serine/threonine-prote ( 502) 661 163.9 6e-40 NP_005596 (OMIM: 114107) serine/threonine-protein ( 512) 661 163.9 6.1e-40 NP_001230903 (OMIM: 114107) serine/threonine-prote ( 521) 661 163.9 6.2e-40 XP_016869099 (OMIM: 114107) PREDICTED: serine/thre ( 439) 644 159.9 8.5e-39 XP_011530341 (OMIM: 602256) PREDICTED: serine/thre ( 753) 367 94.9 5.5e-19 NP_006230 (OMIM: 602256) serine/threonine-protein ( 753) 367 94.9 5.5e-19 NP_689412 (OMIM: 300109) serine/threonine-protein ( 591) 322 84.2 6.8e-16 NP_001276897 (OMIM: 114106) serine/threonine-prote ( 514) 279 74.1 6.7e-13 XP_016885101 (OMIM: 300109) PREDICTED: serine/thre ( 563) 225 61.4 4.8e-09 NP_006231 (OMIM: 300109) serine/threonine-protein ( 653) 225 61.5 5.4e-09 XP_005274610 (OMIM: 300109) PREDICTED: serine/thre ( 653) 225 61.5 5.4e-09 NP_689410 (OMIM: 300109) serine/threonine-protein ( 625) 218 59.8 1.6e-08 >>NP_002706 (OMIM: 176915) serine/threonine-protein phos (309 aa) initn: 2157 init1: 2157 opt: 2157 Z-score: 2742.4 bits: 515.6 E(85289): 5.1e-146 Smith-Waterman score: 2157; 100.0% identity (100.0% similar) in 309 aa overlap (1-309:1-309) 10 20 30 40 50 60 pF1KB5 MDEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MDEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 QFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 RQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 RALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 HQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 HQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHV 250 260 270 280 290 300 pF1KB5 TRRTPDYFL ::::::::: NP_002 TRRTPDYFL >>NP_001009552 (OMIM: 176916) serine/threonine-protein p (309 aa) initn: 2123 init1: 2123 opt: 2123 Z-score: 2699.2 bits: 507.6 E(85289): 1.3e-143 Smith-Waterman score: 2123; 97.4% identity (99.7% similar) in 309 aa overlap (1-309:1-309) 10 20 30 40 50 60 pF1KB5 MDEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHG ::.:.::::::::.:::::::::.:.::..:::::::::::::::::::::::::::::: NP_001 MDDKAFTKELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 QFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHES ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: NP_001 QFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 RQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 RALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 HQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHV 250 260 270 280 290 300 pF1KB5 TRRTPDYFL ::::::::: NP_001 TRRTPDYFL >>NP_001290432 (OMIM: 602035) serine/threonine-protein p (307 aa) initn: 1464 init1: 1442 opt: 1465 Z-score: 1863.1 bits: 352.9 E(85289): 4.9e-97 Smith-Waterman score: 1465; 66.7% identity (86.8% similar) in 303 aa overlap (9-309:6-307) 10 20 30 40 50 60 pF1KB5 MDEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHG .::. :::: .:. ..::.::.:: ::.:::..:::::.: :::::::.:: NP_001 MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHG 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 QFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHES ::.:: ::::.:: :.::::::::.::::.::::: ::.:::::: .:::..:::::: NP_001 QFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHES 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 RQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHI ::::::::::::::::::...::.: :..:::: :.:..::.:::.::::::::.:::.: NP_001 RQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 RALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRA :..:: :::::.:::::::::::.: :::.::::::: ::.:. :: :: . .. :: NP_001 RTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRA 180 190 200 210 220 230 250 260 270 280 290 pF1KB5 HQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPR--RGEP ::::::::.: ...:.:..::::::::::: :::.:::. :. .:. :. ::. :: : NP_001 HQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIP 240 250 260 270 280 290 300 pF1KB5 HVTRRTPDYFL . . :::: NP_001 S-KKPVADYFL 300 >>NP_002711 (OMIM: 602035) serine/threonine-protein phos (307 aa) initn: 1464 init1: 1442 opt: 1465 Z-score: 1863.1 bits: 352.9 E(85289): 4.9e-97 Smith-Waterman score: 1465; 66.7% identity (86.8% similar) in 303 aa overlap (9-309:6-307) 10 20 30 40 50 60 pF1KB5 MDEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHG .::. :::: .:. ..::.::.:: ::.:::..:::::.: :::::::.:: NP_002 MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHG 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 QFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHES ::.:: ::::.:: :.::::::::.::::.::::: ::.:::::: .:::..:::::: NP_002 QFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHES 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 RQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHI ::::::::::::::::::...::.: :..:::: :.:..::.:::.::::::::.:::.: NP_002 RQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 RALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRA :..:: :::::.:::::::::::.: :::.::::::: ::.:. :: :: . .. :: NP_002 RTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRA 180 190 200 210 220 230 250 260 270 280 290 pF1KB5 HQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPR--RGEP ::::::::.: ...:.:..::::::::::: :::.:::. :. .:. :. ::. :: : NP_002 HQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIP 240 250 260 270 280 290 300 pF1KB5 HVTRRTPDYFL . . :::: NP_002 S-KKPVADYFL 300 >>NP_002712 (OMIM: 612725) serine/threonine-protein phos (305 aa) initn: 1240 init1: 1240 opt: 1241 Z-score: 1578.5 bits: 300.2 E(85289): 3.5e-81 Smith-Waterman score: 1241; 58.4% identity (79.9% similar) in 303 aa overlap (9-309:5-305) 10 20 30 40 50 60 pF1KB5 MDEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHG .::...: :: : :...: ::. . ..: .::::: : :::::::.:: NP_002 MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHG 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 QFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHES ::.:: :::: ::. :::::.::::.:::::::.:: : :.:::... .:::.::::::: NP_002 QFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHES 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 RQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHI ::::::::::::: ::::::.:.: : .::.: ..::.: ::.:.::::::.: :::.: NP_002 RQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 RALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRA :...: ::.::.: .:::.::::.: :.:::::::. :: ... : : :.: :. :: NP_002 RTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRA 180 190 200 210 220 230 250 260 270 280 290 pF1KB5 HQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDD--TLKYSFLQFDPAPRRGEP :::: :::.. :...::..::::::::::: :.:: . : : . .... : .: : NP_002 HQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIP 240 250 260 270 280 290 300 pF1KB5 HVTRRTPDYFL : : ::: NP_002 --PRTTTPYFL 300 >>XP_011517149 (OMIM: 612725) PREDICTED: serine/threonin (293 aa) initn: 1185 init1: 1185 opt: 1186 Z-score: 1508.9 bits: 287.2 E(85289): 2.6e-77 Smith-Waterman score: 1186; 60.1% identity (80.8% similar) in 281 aa overlap (31-309:15-293) 10 20 30 40 50 60 pF1KB5 MDEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHG ::. . ..: .::::: : :::::::.:: XP_011 MFLLPRLQLLGQMRLCDYVCDLLLEESNVQPVSTPVTVCGDIHG 10 20 30 40 70 80 90 100 110 120 pF1KB5 QFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHES ::.:: :::: ::. :::::.::::.:::::::.:: : :.:::... .:::.::::::: XP_011 QFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHES 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 RQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHI ::::::::::::: ::::::.:.: : .::.: ..::.: ::.:.::::::.: :::.: XP_011 RQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQI 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB5 RALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRA :...: ::.::.: .:::.::::.: :.:::::::. :: ... : : :.: :. :: XP_011 RTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRA 170 180 190 200 210 220 250 260 270 280 290 pF1KB5 HQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDD--TLKYSFLQFDPAPRRGEP :::: :::.. :...::..::::::::::: :.:: . : : . .... : .: : XP_011 HQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIP 230 240 250 260 270 280 300 pF1KB5 HVTRRTPDYFL : : ::: XP_011 --PRTTTPYFL 290 >>NP_001116827 (OMIM: 612725) serine/threonine-protein p (342 aa) initn: 1225 init1: 1185 opt: 1186 Z-score: 1507.9 bits: 287.3 E(85289): 3e-77 Smith-Waterman score: 1186; 60.1% identity (80.8% similar) in 281 aa overlap (31-309:64-342) 10 20 30 40 50 60 pF1KB5 MDEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHG ::. . ..: .::::: : :::::::.:: NP_001 PSGCGAPAGRPFLSPGPPPVFHFLRFLKERLCDYVCDLLLEESNVQPVSTPVTVCGDIHG 40 50 60 70 80 90 70 80 90 100 110 120 pF1KB5 QFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHES ::.:: :::: ::. :::::.::::.:::::::.:: : :.:::... .:::.::::::: NP_001 QFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHES 100 110 120 130 140 150 130 140 150 160 170 180 pF1KB5 RQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHI ::::::::::::: ::::::.:.: : .::.: ..::.: ::.:.::::::.: :::.: NP_001 RQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQI 160 170 180 190 200 210 190 200 210 220 230 240 pF1KB5 RALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRA :...: ::.::.: .:::.::::.: :.:::::::. :: ... : : :.: :. :: NP_001 RTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRA 220 230 240 250 260 270 250 260 270 280 290 pF1KB5 HQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDD--TLKYSFLQFDPAPRRGEP :::: :::.. :...::..::::::::::: :.:: . : : . .... : .: : NP_001 HQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIP 280 290 300 310 320 330 300 pF1KB5 HVTRRTPDYFL : : ::: NP_001 --PRTTTPYFL 340 >>XP_016878893 (OMIM: 602035) PREDICTED: serine/threonin (228 aa) initn: 1118 init1: 1096 opt: 1117 Z-score: 1422.9 bits: 271.0 E(85289): 1.6e-72 Smith-Waterman score: 1117; 66.8% identity (86.5% similar) in 229 aa overlap (83-309:1-228) 60 70 80 90 100 110 pF1KB5 TVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERIT :::.::::.::::: ::.:::::: .::: XP_016 MGDFVDRGFYSVETFLLLLALKVRYPDRIT 10 20 30 120 130 140 150 160 170 pF1KB5 ILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSP ..::::::::::::::::::::::::...::.: :..:::: :.:..::.:::.:::::: XP_016 LIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSP 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB5 SIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHAN ::.:::.::..:: :::::.:::::::::::.: :::.::::::: ::.:. :: :: XP_016 SIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAAN 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB5 GLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPA . .. ::::::::::.: ...:.:..::::::::::: :::.:::. :. .:. :. : XP_016 DIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAA 160 170 180 190 200 210 300 pF1KB5 PR--RGEPHVTRRTPDYFL :. :: : . . :::: XP_016 PQETRGIPS-KKPVADYFL 220 >>XP_016878892 (OMIM: 602035) PREDICTED: serine/threonin (228 aa) initn: 1118 init1: 1096 opt: 1117 Z-score: 1422.9 bits: 271.0 E(85289): 1.6e-72 Smith-Waterman score: 1117; 66.8% identity (86.5% similar) in 229 aa overlap (83-309:1-228) 60 70 80 90 100 110 pF1KB5 TVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERIT :::.::::.::::: ::.:::::: .::: XP_016 MGDFVDRGFYSVETFLLLLALKVRYPDRIT 10 20 30 120 130 140 150 160 170 pF1KB5 ILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSP ..::::::::::::::::::::::::...::.: :..:::: :.:..::.:::.:::::: XP_016 LIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSP 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB5 SIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHAN ::.:::.::..:: :::::.:::::::::::.: :::.::::::: ::.:. :: :: XP_016 SIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAAN 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB5 GLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPA . .. ::::::::::.: ...:.:..::::::::::: :::.:::. :. .:. :. : XP_016 DIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAA 160 170 180 190 200 210 300 pF1KB5 PR--RGEPHVTRRTPDYFL :. :: : . . :::: XP_016 PQETRGIPS-KKPVADYFL 220 >>NP_001290435 (OMIM: 602035) serine/threonine-protein p (228 aa) initn: 1118 init1: 1096 opt: 1117 Z-score: 1422.9 bits: 271.0 E(85289): 1.6e-72 Smith-Waterman score: 1117; 66.8% identity (86.5% similar) in 229 aa overlap (83-309:1-228) 60 70 80 90 100 110 pF1KB5 TVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERIT :::.::::.::::: ::.:::::: .::: NP_001 MGDFVDRGFYSVETFLLLLALKVRYPDRIT 10 20 30 120 130 140 150 160 170 pF1KB5 ILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSP ..::::::::::::::::::::::::...::.: :..:::: :.:..::.:::.:::::: NP_001 LIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSP 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB5 SIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHAN ::.:::.::..:: :::::.:::::::::::.: :::.::::::: ::.:. :: :: NP_001 SIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAAN 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB5 GLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPA . .. ::::::::::.: ...:.:..::::::::::: :::.:::. :. .:. :. : NP_001 DIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAA 160 170 180 190 200 210 300 pF1KB5 PR--RGEPHVTRRTPDYFL :. :: : . . :::: NP_001 PQETRGIPS-KKPVADYFL 220 309 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 16:32:21 2016 done: Thu Nov 3 16:32:23 2016 Total Scan time: 6.740 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]