FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5306, 646 aa 1>>>pF1KB5306 646 - 646 aa - 646 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3243+/-0.000394; mu= 17.2573+/- 0.025 mean_var=129.4733+/-26.190, 0's: 0 Z-trim(115.3): 36 B-trim: 0 in 0/55 Lambda= 0.112716 statistics sampled from 25628 (25664) to 25628 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.301), width: 16 Scan time: 9.820 The best scores are: opt bits E(85289) XP_011541100 (OMIM: 600816) PREDICTED: heat shock ( 646) 4161 688.4 2.1e-197 NP_006588 (OMIM: 600816) heat shock cognate 71 kDa ( 646) 4161 688.4 2.1e-197 NP_005337 (OMIM: 603012) heat shock 70 kDa protein ( 641) 3625 601.2 3.6e-171 NP_005336 (OMIM: 140550) heat shock 70 kDa protein ( 641) 3625 601.2 3.6e-171 NP_068814 (OMIM: 140560) heat shock-related 70 kDa ( 639) 3590 595.6 1.8e-169 NP_005518 (OMIM: 140559) heat shock 70 kDa protein ( 641) 3488 579.0 1.8e-164 NP_002146 (OMIM: 140555) heat shock 70 kDa protein ( 643) 3363 558.6 2.4e-158 NP_694881 (OMIM: 600816) heat shock cognate 71 kDa ( 493) 2973 495.1 2.5e-139 NP_005338 (OMIM: 138120) 78 kDa glucose-regulated ( 654) 2668 445.6 2.6e-124 NP_004125 (OMIM: 182170,600548,616854) stress-70 p ( 679) 1932 326.0 2.8e-88 NP_057383 (OMIM: 610369) heat shock 70 kDa protein ( 509) 1072 186.0 2.9e-46 NP_002145 (OMIM: 601113) heat shock 70 kDa protein ( 840) 1000 174.5 1.4e-42 XP_016875852 (OMIM: 610703) PREDICTED: heat shock ( 807) 925 162.3 6.2e-39 NP_001273432 (OMIM: 610703) heat shock protein 105 ( 814) 925 162.3 6.3e-39 XP_016875850 (OMIM: 610703) PREDICTED: heat shock ( 851) 923 162.0 8.1e-39 NP_006635 (OMIM: 610703) heat shock protein 105 kD ( 858) 923 162.0 8.2e-39 XP_016875851 (OMIM: 610703) PREDICTED: heat shock ( 809) 840 148.5 9.1e-35 XP_005266293 (OMIM: 610703) PREDICTED: heat shock ( 816) 840 148.5 9.1e-35 XP_011533189 (OMIM: 610703) PREDICTED: heat shock ( 853) 838 148.2 1.2e-34 NP_001273433 (OMIM: 610703) heat shock protein 105 ( 860) 838 148.2 1.2e-34 NP_008879 (OMIM: 601100) heat shock 70 kDa protein ( 471) 714 127.8 9.1e-29 XP_016875853 (OMIM: 610703) PREDICTED: heat shock ( 736) 509 94.6 1.4e-18 NP_001273434 (OMIM: 610703) heat shock protein 105 ( 782) 490 91.5 1.2e-17 XP_011533190 (OMIM: 610703) PREDICTED: heat shock ( 780) 487 91.0 1.7e-17 NP_006380 (OMIM: 601746) hypoxia up-regulated prot ( 999) 396 76.4 5.7e-13 XP_016872585 (OMIM: 601746) PREDICTED: hypoxia up- ( 999) 396 76.4 5.7e-13 XP_016872586 (OMIM: 601746) PREDICTED: hypoxia up- ( 999) 396 76.4 5.7e-13 NP_001124463 (OMIM: 601746) hypoxia up-regulated p ( 999) 396 76.4 5.7e-13 XP_016872584 (OMIM: 601746) PREDICTED: hypoxia up- (1000) 396 76.4 5.7e-13 XP_005271450 (OMIM: 601746) PREDICTED: hypoxia up- (1000) 396 76.4 5.7e-13 XP_005271449 (OMIM: 601746) PREDICTED: hypoxia up- (1000) 396 76.4 5.7e-13 XP_005271451 (OMIM: 601746) PREDICTED: hypoxia up- (1000) 396 76.4 5.7e-13 XP_016864924 (OMIM: 609963) PREDICTED: chondroitin ( 449) 248 52.0 5.7e-06 NP_001265134 (OMIM: 610369) heat shock 70 kDa prot ( 143) 232 48.9 1.5e-05 >>XP_011541100 (OMIM: 600816) PREDICTED: heat shock cogn (646 aa) initn: 4161 init1: 4161 opt: 4161 Z-score: 3665.1 bits: 688.4 E(85289): 2.1e-197 Smith-Waterman score: 4161; 100.0% identity (100.0% similar) in 646 aa overlap (1-646:1-646) 10 20 30 40 50 60 pF1KB5 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE 550 560 570 580 590 600 610 620 630 640 pF1KB5 KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD :::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 610 620 630 640 >>NP_006588 (OMIM: 600816) heat shock cognate 71 kDa pro (646 aa) initn: 4161 init1: 4161 opt: 4161 Z-score: 3665.1 bits: 688.4 E(85289): 2.1e-197 Smith-Waterman score: 4161; 100.0% identity (100.0% similar) in 646 aa overlap (1-646:1-646) 10 20 30 40 50 60 pF1KB5 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE 550 560 570 580 590 600 610 620 630 640 pF1KB5 KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD :::::::::::::::::::::::::::::::::::::::::::::: NP_006 KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 610 620 630 640 >>NP_005337 (OMIM: 603012) heat shock 70 kDa protein 1B (641 aa) initn: 3533 init1: 3533 opt: 3625 Z-score: 3194.1 bits: 601.2 E(85289): 3.6e-171 Smith-Waterman score: 3625; 85.6% identity (95.4% similar) in 646 aa overlap (1-646:1-641) 10 20 30 40 50 60 pF1KB5 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA :.:. :.::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS .:: ::::::::::::.: : :::::::::::.:.::. .::::: ::::::.:::::.: NP_005 LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEIS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA :::::::::::::::: :::::.::::::::::::::::::.::::::::::::::::: NP_005 SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH ::::::. .:::::::::::::::::::::.:::::::.:::::::::::::::.::: NP_005 IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA :. :::::::::::.::::::::::::::::::::::::::.:::::.:::::::::::: NP_005 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN ::::: .::::.::.:::::::::::::.::::.:::::::::::.::::::::::..:: NP_005 RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI :::::::::::::::::::: :::::::::::::::.:::::.::::::::.:::::.:: NP_005 KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI :::::: ::::::::::::::::::::::::::::::.:::.:::::::::::::::::: NP_005 PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN ::::::::.:.:::::: :::::::::::::::.:::::::::::::::: ::..::.:: NP_005 DANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE .:::::::::..:::: :.:::.. ::.:.::::.:.:.::: : :::.::::..:::: NP_005 ALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELE 550 560 570 580 590 600 610 620 630 640 pF1KB5 KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD .::::::. :::.::: :: :::: :. :.::..::::::::: NP_005 QVCNPIISGLYQGAGG-PG--PGGF--GAQGPKGGSGSGPTIEEVD 610 620 630 640 >>NP_005336 (OMIM: 140550) heat shock 70 kDa protein 1A (641 aa) initn: 3533 init1: 3533 opt: 3625 Z-score: 3194.1 bits: 601.2 E(85289): 3.6e-171 Smith-Waterman score: 3625; 85.6% identity (95.4% similar) in 646 aa overlap (1-646:1-641) 10 20 30 40 50 60 pF1KB5 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA :.:. :.::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS .:: ::::::::::::.: : :::::::::::.:.::. .::::: ::::::.:::::.: NP_005 LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEIS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA :::::::::::::::: :::::.::::::::::::::::::.::::::::::::::::: NP_005 SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH ::::::. .:::::::::::::::::::::.:::::::.:::::::::::::::.::: NP_005 IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA :. :::::::::::.::::::::::::::::::::::::::.:::::.:::::::::::: NP_005 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN ::::: .::::.::.:::::::::::::.::::.:::::::::::.::::::::::..:: NP_005 RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI :::::::::::::::::::: :::::::::::::::.:::::.::::::::.:::::.:: NP_005 KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI :::::: ::::::::::::::::::::::::::::::.:::.:::::::::::::::::: NP_005 PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN ::::::::.:.:::::: :::::::::::::::.:::::::::::::::: ::..::.:: NP_005 DANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE .:::::::::..:::: :.:::.. ::.:.::::.:.:.::: : :::.::::..:::: NP_005 ALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELE 550 560 570 580 590 600 610 620 630 640 pF1KB5 KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD .::::::. :::.::: :: :::: :. :.::..::::::::: NP_005 QVCNPIISGLYQGAGG-PG--PGGF--GAQGPKGGSGSGPTIEEVD 610 620 630 640 >>NP_068814 (OMIM: 140560) heat shock-related 70 kDa pro (639 aa) initn: 3655 init1: 2468 opt: 3590 Z-score: 3163.3 bits: 595.6 E(85289): 1.8e-169 Smith-Waterman score: 3624; 86.4% identity (95.8% similar) in 647 aa overlap (2-646:3-639) 10 20 30 40 50 pF1KB5 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQV ..:::.:::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 MSARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 AMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEV :::::::.:::::::::.:.::.:::::::::: ::...:.::::::::::::.:.:::. NP_068 AMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 SSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAA ::::::::::::::::: : .::.::::::::::::::::::::.:::::::::::::: NP_068 SSMVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 AIAYGLDKK--VGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRM ::::::::: .:.:.:::::::::::::::::::::::::::::::::::::::::::: NP_068 AIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRM 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB5 VNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSI :.:. ::::::::::. :::::::::::::::::::::::::::::::::::.:::::: NP_068 VSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSI 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB5 TRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGK :::::::::::::::::.:::::::::::::.::..:::::::::::::::::::::::: NP_068 TRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGK 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB5 ELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRN ::::::::::::::::::::::: :::::::::::::::::::::::::::::: ::::: NP_068 ELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRN 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB5 TTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVT :::::::::::::::::: .::.:::::::::::::::::::.::::::::::::::::: NP_068 TTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVT 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB5 FDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVS :::::::::::.:.:::::::::::::::::::::.::.:::::::.::.::: .::.:. NP_068 FDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVA 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB5 SKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQK .::.::::..:.: :::::::.:::...::.::::::.:.:::::.:: :::.:.::.:: NP_068 AKNALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQK 550 560 570 580 590 600 600 610 620 630 640 pF1KB5 ELEKVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD :::.::::::.:::: :: ::: :::. .:::.:::::::: NP_068 ELERVCNPIISKLYQ--GG-----PGGGSGGGG---SGASGGPTIEEVD 610 620 630 >>NP_005518 (OMIM: 140559) heat shock 70 kDa protein 1-l (641 aa) initn: 3448 init1: 3448 opt: 3488 Z-score: 3073.7 bits: 579.0 E(85289): 1.8e-164 Smith-Waterman score: 3488; 82.8% identity (93.8% similar) in 645 aa overlap (2-646:4-641) 10 20 30 40 50 pF1KB5 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQ .:: :.::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MATAKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 VAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEE ::::: ::::::::::::.:.: :::.::: :::.:.:..:.::: : ::::.:.::::: NP_005 VAMNPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 VSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTA .:::::::.:: :::.::. :::::.::::::::::::::::::.::::::::::::::: NP_005 ISSMVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 AAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMV ::::::::: .::.::::::::::::::::::.:::::::.:::::::::::::::.: NP_005 AAIAYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB5 NHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSIT .::. :::::::::::.:::::::::::::::::::::::::..:::::::::::::::: NP_005 SHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSIT 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB5 RARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKE ::::::: ::::::::.::::::::::.::..:::::::::::::::.:.::::.:::.. NP_005 RARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRD 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB5 LNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNT :::::::::::::::::::::: :::::.:::::::::.:::::.::::::::.:::::. NP_005 LNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNS 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB5 TIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTF :::::::: ::::::::::::::::::::::::::::::.:.:::::::::::::::::: NP_005 TIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTF 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB5 DIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSS ::::::::::.:.:::::: :::::::::::::::.::::: .::::::::: ::.:... NP_005 DIDANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAA 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB5 KNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKE ::.:::::::::..: :: :.:::.. ::.::::::::...::. :: :::.::.:..:: NP_005 KNALESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKE 550 560 570 580 590 600 600 610 620 630 640 pF1KB5 LEKVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD ::..:::::::::: :: : : : : : ..:::::::: NP_005 LEQMCNPIITKLYQ------GGCTGPACGTGYVP-GRPATGPTIEEVD 610 620 630 640 >>NP_002146 (OMIM: 140555) heat shock 70 kDa protein 6 [ (643 aa) initn: 3368 init1: 3293 opt: 3363 Z-score: 2963.8 bits: 558.6 E(85289): 2.4e-158 Smith-Waterman score: 3363; 78.3% identity (93.8% similar) in 641 aa overlap (6-646:8-643) 10 20 30 40 50 pF1KB5 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQ :::::::::::::::::.:.:::.:::::::::::::::::::::.:::::.: NP_002 MQAPRELAVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 VAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEE .:.:: ::::::::::::.: :..:::::::::: ::...:.:::.: :.:: :.::::: NP_002 AALNPHNTVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 VSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTA .:::::.:::: ::::::. : .::.::::::::::::::::::.::::::::::::::: NP_002 ISSMVLSKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 AAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMV ::::::::.. ..:::::::::::::::::.:.:. :.::::.:::::::::::::::.: NP_002 AAIAYGLDRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLV 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB5 NHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSIT :::. ::.::: ::.: ::::.::::::::::::::::::::..:::::.::.::::::: NP_002 NHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSIT 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB5 RARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKE ::::::: .::::.::.:::::::::::::.::::.:::::::::::.:::::::::::: NP_002 RARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB5 LNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNT ::::::::::::::::::::.: ::: :.:::::::::.:::::.::::::::.::.::. NP_002 LNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNA 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB5 TIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTF ::::::::::::::::::::.::::::::::::::::::.:::.:::::::::::::::: NP_002 TIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTF 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB5 DIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSS ::::::::.:.:.:.:::: :::::::::::::::..::::.:::.:::::: :::.:.. NP_002 DIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAA 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB5 KNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKE :::::...:..:.....:.:. :: .::..:. ::: :.. ::..:: :::::.:::..: NP_002 KNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRE 550 560 570 580 590 600 600 610 620 630 640 pF1KB5 LEKVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD ::..: ::...:: :: :: .::: : .: :.:: ::::: NP_002 LEQICRPIFSRLY---GG-PG-VPGGSSCGTQARQGDPSTGPIIEEVD 610 620 630 640 >>NP_694881 (OMIM: 600816) heat shock cognate 71 kDa pro (493 aa) initn: 3024 init1: 2963 opt: 2973 Z-score: 2622.5 bits: 495.1 E(85289): 2.5e-139 Smith-Waterman score: 2973; 98.7% identity (99.2% similar) in 473 aa overlap (1-472:1-473) 10 20 30 40 50 60 pF1KB5 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_694 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_694 MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_694 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_694 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_694 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_694 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_694 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI 370 380 390 400 410 420 430 440 450 460 470 pF1KB5 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPA-PRGVPQIEVTFD :::::::::::::::::::::::::::::::::::::::::::.: . : : : NP_694 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFPGGGAPPS 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB5 IDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSK NP_694 GGASSGPTIEEVD 490 >>NP_005338 (OMIM: 138120) 78 kDa glucose-regulated prot (654 aa) initn: 2008 init1: 1048 opt: 2668 Z-score: 2352.9 bits: 445.6 E(85289): 2.6e-124 Smith-Waterman score: 2668; 66.1% identity (86.6% similar) in 620 aa overlap (4-620:28-644) 10 20 30 pF1KB5 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNR : .:::::::::::::::..:.::::::::::: NP_005 MKLSLVAAMLLLLSAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 TTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVV :::::::: . :::::::::::.. :: :::::::::::: ..: ::.:.: :: :: NP_005 ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 NDAGRPKVQVEYKG-ETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQ . .: .::. : .::.: :::.:.:::::::: ::::::: ::.:::::::::::.: NP_005 EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB5 RQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIED :::::::::::::::.:::::::::::::::::. : :.:.:.:::::::::::.:::.. NP_005 RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREG-EKNILVFDLGGGTFDVSLLTIDN 190 200 210 220 230 220 230 240 250 260 270 pF1KB5 GIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTL :.::: .: :::::::::::.:...::: .:.: ::. ...:::..:: :.:::.: NP_005 GVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRAL 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB5 SSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDI ::. :: :::.:.::: :: ..:::.::::: ::::.:. ::.:.:.:. : ::.: .: NP_005 SSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEI 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB5 VLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLL :::::::::::::.:...:::::: ...:::::::::::::::..:::: ... ::.:: NP_005 VLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGD--QDTGDLVLL 360 370 380 390 400 410 400 410 420 430 440 450 pF1KB5 DVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNN :: ::.:::::.::::: :: :::..:::..: :.: ::::: : :.:::::: .::::. NP_005 DVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNH 420 430 440 450 460 470 460 470 480 490 500 510 pF1KB5 LLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKED ::: :.::::::::::::::::::.::.:::: :.: ::.::..::::::::..::. :. NP_005 LLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEE 480 490 500 510 520 530 520 530 540 550 560 570 pF1KB5 IERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVED-EKLQGKINDEDKQKILDK :::::..:::. ::.: .......: :::::...: . : ::: ::...:::. . NP_005 IERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKA 540 550 560 570 580 590 580 590 600 610 620 630 pF1KB5 CNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPS .: :.::...: :. :.:. ..::::.. .:::.::: ::: : : NP_005 VEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTAEKDEL 600 610 620 630 640 650 640 pF1KB5 GGASSGPTIEEVD >>NP_004125 (OMIM: 182170,600548,616854) stress-70 prote (679 aa) initn: 1777 init1: 539 opt: 1932 Z-score: 1705.9 bits: 326.0 E(85289): 2.8e-88 Smith-Waterman score: 1932; 50.6% identity (76.7% similar) in 634 aa overlap (3-629:52-668) 10 20 30 pF1KB5 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIAND :: .:::::::: :::.:.. ..... : NP_004 TAARHQDSWNGLSHEAFRLVSRRDYASEAIKGAVVGIDLGTTNSCVAVMEGKQAKVLENA 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB5 QGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWP .: ::::: :::: : :::.: :: :.. ::.:: . .:::::::.:: ::.:.:. : NP_004 EGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYATKRLIGRRYDDPEVQKDIKNVP 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB5 FMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFN : .: :. . :: .: : . : .....:: :::: :: :::.:. :::.::::::: NP_004 FKIVR-ASNGDAWVEAHG--KLYSPSQIGAFVLMKMKETAENYLGHTAKNAVITVPAYFN 150 160 170 180 190 160 170 180 190 200 210 pF1KB5 DSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILT ::::::::::: :.::::::.::::::::.:::::: . .. . ..::::::::.::: NP_004 DSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDK--SEDKVIAVYDLGGGTFDISILE 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB5 IEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAK :. :.:::::: ::: :::::::. .. :.. ::::. :..... :..:.: : :.:: NP_004 IQKGVFEVKSTNGDTFLGGEDFDQALLRHIVKEFKRETGVDLTKDNMALQRVREAAEKAK 260 270 280 290 300 310 280 290 300 310 320 pF1KB5 RTLSSSTQASIEIDSLYEGID------FYTSITRARFEELNADLFRGTLDPVEKALRDAK ::::.:..:.. : .: . ..:::.:: . .::.: :. : .::..::. NP_004 CELSSSVQTDINLP--YLTMDSSGPKHLNMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAE 320 330 340 350 360 370 330 340 350 360 370 380 pF1KB5 LDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKS ..::.: ...:::: ::.::.:. .::.: :. .:..::::::: :::.:...:.:: NP_004 VSKSDIGEVILVGGMTRMPKVQQTVQDLF-GRAPSKAVNPDEAVAIGAAIQGGVLAGD-- 380 390 400 410 420 430 390 400 410 420 430 440 pF1KB5 ENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEG : :.:::::::::::::: :::.: ::.::::::::..:.:.: .:.: : :.: .: NP_004 --VTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQG 440 450 460 470 480 450 460 470 480 490 500 pF1KB5 ERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITN :: :. ::.:::.: : :::::::::::::::::::::::..::: ::.::.:..:.: . NP_004 EREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQS 490 500 510 520 530 540 510 520 530 540 550 560 pF1KB5 DKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDE . : :::.::: ::..:::: ::......: . : :. . .. .:. : : .. NP_004 SGG-LSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADEC 550 560 570 580 590 600 570 580 590 600 610 620 pF1KB5 DKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQSAGGMPGGMPGGF .: : .. ... . : .... :.... . :... .. :.. .. : .: NP_004 NKLK--EEISKMRELLARKDSETGENIRQAASSLQQASLKLFEMAYKKMASEREG--SGS 610 620 630 640 650 660 630 640 pF1KB5 PGGGAPPSGGASSGPTIEEVD : : NP_004 SGTGEQKEDQKEEKQ 670 646 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:05:40 2016 done: Fri Nov 4 22:05:41 2016 Total Scan time: 9.820 Total Display time: 0.160 Function used was FASTA [36.3.4 Apr, 2011]