Result of FASTA (ccds) for
pF1KB5307
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5307, 412 aa
1>>>pF1KB5307 412 - 412 aa - 412 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3489+/-0.000878; mu= 16.9952+/- 0.053
mean_var=68.1203+/-13.847, 0's: 0 Z-trim(106.1): 25 B-trim: 0 in 0/49
Lambda= 0.155395
statistics sampled from 8759 (8773) to 8759 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.269), width: 16
Scan time: 2.880
The best scores are: opt bits E(32554)
CCDS10705.1 BCKDK gene_id:10295|Hs108|chr16 ( 412) 2751 625.8 2.3e-179
CCDS45467.1 BCKDK gene_id:10295|Hs108|chr16 ( 365) 2442 556.5 1.5e-158
CCDS61917.1 BCKDK gene_id:10295|Hs108|chr16 ( 335) 1881 430.7 9.9e-121
CCDS2250.1 PDK1 gene_id:5163|Hs108|chr2 ( 436) 289 73.9 3.4e-13
CCDS11559.1 PDK2 gene_id:5164|Hs108|chr17 ( 407) 288 73.6 3.7e-13
CCDS5643.1 PDK4 gene_id:5166|Hs108|chr7 ( 411) 279 71.6 1.5e-12
>>CCDS10705.1 BCKDK gene_id:10295|Hs108|chr16 (412 aa)
initn: 2751 init1: 2751 opt: 2751 Z-score: 3333.7 bits: 625.8 E(32554): 2.3e-179
Smith-Waterman score: 2751; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412)
10 20 30 40 50 60
pF1KB5 MILASVLRSGPGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MILASVLRSGPGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAID
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 AAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 TILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 TILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 TIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQS
310 320 330 340 350 360
370 380 390 400 410
pF1KB5 GPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREESFRI
::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 GPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREESFRI
370 380 390 400 410
>>CCDS45467.1 BCKDK gene_id:10295|Hs108|chr16 (365 aa)
initn: 2442 init1: 2442 opt: 2442 Z-score: 2960.1 bits: 556.5 E(32554): 1.5e-158
Smith-Waterman score: 2442; 100.0% identity (100.0% similar) in 365 aa overlap (1-365:1-365)
10 20 30 40 50 60
pF1KB5 MILASVLRSGPGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MILASVLRSGPGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAID
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 AAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 TILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 TILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 TIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQS
310 320 330 340 350 360
370 380 390 400 410
pF1KB5 GPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREESFRI
:::::
CCDS45 GPMHG
>>CCDS61917.1 BCKDK gene_id:10295|Hs108|chr16 (335 aa)
initn: 1881 init1: 1881 opt: 1881 Z-score: 2281.0 bits: 430.7 E(32554): 9.9e-121
Smith-Waterman score: 2181; 91.8% identity (91.8% similar) in 365 aa overlap (1-365:1-335)
10 20 30 40 50 60
pF1KB5 MILASVLRSGPGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 MILASVLRSGPGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAID
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 AAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 TILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 TILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVI
::::::::::::::::::::::::::::::::::::::::::
CCDS61 LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMR------------------
250 260 270 280
310 320 330 340 350 360
pF1KB5 TIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQS
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 ------------ISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQS
290 300 310 320 330
370 380 390 400 410
pF1KB5 GPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREESFRI
:::::
CCDS61 GPMHG
>>CCDS2250.1 PDK1 gene_id:5163|Hs108|chr2 (436 aa)
initn: 540 init1: 146 opt: 289 Z-score: 350.4 bits: 73.9 E(32554): 3.4e-13
Smith-Waterman score: 552; 32.9% identity (61.2% similar) in 340 aa overlap (93-407:78-398)
70 80 90 100 110 120
pF1KB5 AEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNPTI
.:.::::::.:. .: . :: . .:..
CCDS22 FYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSV
50 60 70 80 90 100
130 140 150 160 170
pF1KB5 LHVHELYIRAFQKLTDFPPIKDQ-ADEAQ----YCQLVRQLLDDHKDVVTLLAEGLRESR
:. ::...:.: :: ::. :..:. . . : .. . :.::. .:.:. : .
CCDS22 QLVQSWYIQSLQELLDF---KDKSAEDAKAIYDFTDTVIRIRNRHNDVIPTMAQGVIEYK
110 120 130 140 150 160
180 190 200 210 220
pF1KB5 KHIEDEKL----VRYFLDKTLTSRLGIRMLATHHLALHEDK----PDF---VGIICTRLS
. . . . :.::::. ::..:::: ..: : : :. .: : .
CCDS22 ESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGSPSHRKHIGSINPNCN
170 180 190 200 210 220
230 240 250 260 270
pF1KB5 PKKIIEKWVDFARRLCEHKYGNAPRVRINGHVAARFP-------FIPMPLDYILPELLKN
..:. . :::::. : :.:..... .. :. : ..: : ... ::.::
CCDS22 VLEVIKDGYENARRLCDLYYINSPELELE-ELNAKSPGQPIQVVYVPSHLYHMVFELFKN
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB5 AMRATMESHLDTPYNVPDVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEAS
::::::: : . : . . .. .. :: ...::::::. . .::...: ..::
CCDS22 AMRATMEHHANRGV-YPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPR-
290 300 310 320 330 340
340 350 360 370 380 390
pF1KB5 TQDPRISPLFGHLDMHSGAQSGPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTD--VY
::. ... :. :::.::: :: ::.:. :.:.: ::.: ::: .:
CCDS22 ---PRVET----------SRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIY
350 360 370 380
400 410
pF1KB5 LRLRHIDGREESFRI
.. :. :
CCDS22 IKALSTDSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRSA
390 400 410 420 430
>>CCDS11559.1 PDK2 gene_id:5164|Hs108|chr17 (407 aa)
initn: 448 init1: 149 opt: 288 Z-score: 349.6 bits: 73.6 E(32554): 3.7e-13
Smith-Waterman score: 565; 32.8% identity (60.7% similar) in 338 aa overlap (90-407:49-369)
60 70 80 90 100 110
pF1KB5 DAAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCN
: .:.::::::.:. .: . :: . .
CCDS11 YIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINLLPDRVLST
20 30 40 50 60 70
120 130 140 150 160 170
pF1KB5 PTILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLL---DDHKDVVTLLAEGLRES
:.. :. :.... . .: :: :. :.. :. . :.::: .:.:. :
CCDS11 PSVQLVQSWYVQSLLDIMEFLD-KDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEY
80 90 100 110 120 130
180 190 200 210 220
pF1KB5 RKHIEDEKL----VRYFLDKTLTSRLGIRMLATHHLALHEDK-----PDFVGIICTRLSP
. :. . ..::::. ::..:::: ..: . . . : .: : .
CCDS11 KDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDGSTNPAHPKHIGSIDPNCNV
140 150 160 170 180 190
230 240 250 260 270 280
pF1KB5 KKIIEKWVDFARRLCEHKYGNAPRVRINGHVAA--RFP----FIPMPLDYILPELLKNAM
..... :.:. ::.. : .: ..:. :: . : ..: : ..: ::.::::
CCDS11 SEVVKDAYDMAKLLCDKYYMASPDLEIQEINAANSKQPIHMVYVPSHLYHMLFELFKNAM
200 210 220 230 240 250
290 300 310 320 330 340
pF1KB5 RATMESHLDTPYNVPDVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQ
:::.::: .. .: . . .: .. :: :..::::::. . ..:...: ..::
CCDS11 RATVESH-ESSLILPPIKVMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTA-----
260 270 280 290 300 310
350 360 370 380 390
pF1KB5 DPRISPLFGHLDMHSGAQSGPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTD--VYLR
: .: :. . :. :::.::: :: ::.:. :.::: :..:.::: .::.
CCDS11 -PTPQP---------GTGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLK
320 330 340 350 360
400 410
pF1KB5 LRHIDGREESFRI
:. :
CCDS11 ALSTDSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS
370 380 390 400
>>CCDS5643.1 PDK4 gene_id:5166|Hs108|chr7 (411 aa)
initn: 462 init1: 144 opt: 279 Z-score: 338.7 bits: 71.6 E(32554): 1.5e-12
Smith-Waterman score: 534; 31.1% identity (63.4% similar) in 328 aa overlap (93-401:56-365)
70 80 90 100 110 120
pF1KB5 AEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNPTI
.:.::::::.:. .: . :: . . ..
CCDS56 HFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPTQLVNTSSV
30 40 50 60 70 80
130 140 150 160 170
pF1KB5 LHVHELYIRAFQKLTDF---PPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKH
:. ::.... :..: : :: ... . . .. . :..:: .:.:. : .
CCDS56 QLVKSWYIQSLMDLVEFHEKSP-DDQKALSDFVDTLIKVRNRHHNVVPTMAQGIIEYKDA
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB5 -----IEDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDK----PDFVGIICTRLSPKKI
. ...: .::::. .:.. ::: ..:. . :. :. .: : . .
CCDS56 CTVDPVTNQNL-QYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPSHIGSIDPNCDVVAV
150 160 170 180 190 200
240 250 260 270 280
pF1KB5 IEKWVDFARRLCEHKYGNAPRVRINGHVAARFP-------FIPMPLDYILPELLKNAMRA
.. . .: ::.. : ..:..... .: ..:: ..: : ..: ::.::::::
CCDS56 VQDAFECSRMLCDQYYLSSPELKLT-QVNGKFPDQPIHIVYVPSHLHHMLFELFKNAMRA
210 220 230 240 250 260
290 300 310 320 330 340
pF1KB5 TMESHLDTPYNVPDVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDP
:.: . . : .: ::.. ... :: :.:::::::. . .::...: ..:: . ..:
CCDS56 TVEHQENQPSLTPIEVIVVLGKE-DLTIKISDRGGGVPLRIIDRLFSYTYSTAPTPVMD-
270 280 290 300 310 320
350 360 370 380 390 400
pF1KB5 RISPLFGHLDMHSGAQSGPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHI
.....:. :::.::: :: ::.:. :.:.: ::.: :::. . :.
CCDS56 -------------NSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKAL
330 340 350 360
410
pF1KB5 DGREESFRI
CCDS56 SSESIEKLPVFNKSAFKHYQMSSEADDWCIPSREPKNLAKEVAM
370 380 390 400 410
412 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 12:27:40 2016 done: Sat Nov 5 12:27:41 2016
Total Scan time: 2.880 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]