FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5311, 466 aa 1>>>pF1KB5311 466 - 466 aa - 466 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1203+/-0.000463; mu= 9.6331+/- 0.028 mean_var=199.3919+/-42.361, 0's: 0 Z-trim(115.3): 186 B-trim: 448 in 1/52 Lambda= 0.090828 statistics sampled from 25385 (25606) to 25385 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.3), width: 16 Scan time: 9.750 The best scores are: opt bits E(85289) NP_002427 (OMIM: 305360) 55 kDa erythrocyte membra ( 466) 3072 415.8 1.2e-115 NP_001159934 (OMIM: 305360) 55 kDa erythrocyte mem ( 436) 2856 387.5 3.9e-107 NP_001159932 (OMIM: 305360) 55 kDa erythrocyte mem ( 449) 2542 346.4 9.6e-95 XP_011529471 (OMIM: 305360) PREDICTED: 55 kDa eryt ( 340) 2043 280.9 3.9e-75 NP_001159933 (OMIM: 305360) 55 kDa erythrocyte mem ( 446) 1903 262.6 1.5e-69 XP_006724629 (OMIM: 300172,300422,300749) PREDICTE ( 885) 1810 250.8 1.1e-65 XP_011542298 (OMIM: 300172,300422,300749) PREDICTE ( 891) 1810 250.8 1.1e-65 XP_011529469 (OMIM: 305360) PREDICTED: 55 kDa eryt ( 439) 1729 239.8 1.1e-62 XP_011542299 (OMIM: 300172,300422,300749) PREDICTE ( 735) 1403 197.4 1.1e-49 NP_001119527 (OMIM: 300172,300422,300749) peripher ( 897) 1403 197.5 1.3e-49 XP_011542297 (OMIM: 300172,300422,300749) PREDICTE ( 903) 1403 197.5 1.3e-49 XP_005272743 (OMIM: 300172,300422,300749) PREDICTE ( 920) 1403 197.5 1.3e-49 XP_011542295 (OMIM: 300172,300422,300749) PREDICTE ( 926) 1403 197.5 1.3e-49 XP_011542296 (OMIM: 300172,300422,300749) PREDICTE ( 914) 1398 196.8 2e-49 NP_001119526 (OMIM: 300172,300422,300749) peripher ( 898) 1353 190.9 1.2e-47 NP_003679 (OMIM: 300172,300422,300749) peripheral ( 921) 1351 190.7 1.5e-47 XP_011513727 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 1066 153.1 1.8e-36 XP_016867805 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 1066 153.1 1.8e-36 XP_006715801 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 1066 153.1 1.8e-36 XP_006715803 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 1066 153.1 1.8e-36 XP_016867806 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 1066 153.1 1.8e-36 NP_001289966 (OMIM: 606959) MAGUK p55 subfamily me ( 540) 1066 153.1 1.8e-36 XP_016867804 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 1066 153.1 1.8e-36 XP_006715802 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 1066 153.1 1.8e-36 NP_057531 (OMIM: 606959) MAGUK p55 subfamily membe ( 540) 1066 153.1 1.8e-36 XP_005249832 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 428) 1059 152.0 2.9e-36 NP_001265304 (OMIM: 600723) MAGUK p55 subfamily me ( 541) 1040 149.7 1.9e-35 NP_001265302 (OMIM: 600723) MAGUK p55 subfamily me ( 541) 1040 149.7 1.9e-35 NP_001265300 (OMIM: 600723) MAGUK p55 subfamily me ( 541) 1040 149.7 1.9e-35 NP_005365 (OMIM: 600723) MAGUK p55 subfamily membe ( 552) 1040 149.7 1.9e-35 NP_001265310 (OMIM: 600723) MAGUK p55 subfamily me ( 552) 1040 149.7 1.9e-35 NP_001265305 (OMIM: 600723) MAGUK p55 subfamily me ( 569) 1040 149.7 2e-35 NP_001265301 (OMIM: 600723) MAGUK p55 subfamily me ( 576) 1040 149.7 2e-35 NP_001265299 (OMIM: 600723) MAGUK p55 subfamily me ( 597) 1040 149.7 2e-35 XP_011523129 (OMIM: 600723) PREDICTED: MAGUK p55 s ( 630) 1040 149.7 2.1e-35 NP_001265303 (OMIM: 600723) MAGUK p55 subfamily me ( 413) 993 143.4 1.1e-33 XP_005252426 (OMIM: 610973) PREDICTED: MAGUK p55 s ( 318) 510 79.9 1.1e-14 XP_016871232 (OMIM: 610973) PREDICTED: MAGUK p55 s ( 399) 510 80.1 1.3e-14 XP_016872781 (OMIM: 603583) PREDICTED: disks large ( 361) 478 75.8 2.2e-13 XP_016872780 (OMIM: 603583) PREDICTED: disks large ( 363) 478 75.8 2.2e-13 NP_001136174 (OMIM: 603583) disks large homolog 2 ( 334) 476 75.5 2.5e-13 NP_001136172 (OMIM: 603583) disks large homolog 2 ( 749) 478 76.2 3.5e-13 XP_011543090 (OMIM: 603583) PREDICTED: disks large ( 767) 478 76.2 3.5e-13 XP_016884816 (OMIM: 300189,300850) PREDICTED: disk ( 334) 472 75.0 3.6e-13 XP_016872774 (OMIM: 603583) PREDICTED: disks large ( 796) 478 76.2 3.6e-13 XP_016872772 (OMIM: 603583) PREDICTED: disks large ( 810) 478 76.2 3.7e-13 XP_005273868 (OMIM: 603583) PREDICTED: disks large ( 819) 478 76.2 3.7e-13 XP_016872769 (OMIM: 603583) PREDICTED: disks large ( 820) 478 76.2 3.7e-13 XP_016872770 (OMIM: 603583) PREDICTED: disks large ( 820) 478 76.2 3.7e-13 XP_016872768 (OMIM: 603583) PREDICTED: disks large ( 821) 478 76.2 3.7e-13 >>NP_002427 (OMIM: 305360) 55 kDa erythrocyte membrane p (466 aa) initn: 3072 init1: 3072 opt: 3072 Z-score: 2197.1 bits: 415.8 E(85289): 1.2e-115 Smith-Waterman score: 3072; 100.0% identity (100.0% similar) in 466 aa overlap (1-466:1-466) 10 20 30 40 50 60 pF1KB5 MTLKASEGESGGSMHTALSDLYLEHLLQKRSRPEAVSHPLNTVTEDMYTNGSPAPGSPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MTLKASEGESGGSMHTALSDLYLEHLLQKRSRPEAVSHPLNTVTEDMYTNGSPAPGSPAQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VKGQEVRKVRLIQFEKVTEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VKGQEVRKVRLIQFEKVTEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NGTNVTNHSVDQLQKAMKETKGMISLKVIPNQQSRLPALQMFMRAQFDYDPKKDNLIPCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NGTNVTNHSVDQLQKAMKETKGMISLKVIPNQQSRLPALQMFMRAQFDYDPKKDNLIPCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 EAGLKFATGDIIQIINKDDSNWWQGRVEGSSKESAGLIPSPELQEWRVASMAQSAPSEAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EAGLKFATGDIIQIINKDDSNWWQGRVEGSSKESAGLIPSPELQEWRVASMAQSAPSEAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SCSPFGKKKKYKDKYLAKHSSIFDQLDVVSYEEVVRLPAFKRKTLVLIGASGVGRSHIKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SCSPFGKKKKYKDKYLAKHSSIFDQLDVVSYEEVVRLPAFKRKTLVLIGASGVGRSHIKN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 ALLSQNPEKFVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQGNMFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ALLSQNPEKFVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQGNMFG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 TKFETVHQIHKQNKIAILDIEPQTLKIVRTAELSPFIVFIAPTDQGTQTEALQQLQKDSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TKFETVHQIHKQNKIAILDIEPQTLKIVRTAELSPFIVFIAPTDQGTQTEALQQLQKDSE 370 380 390 400 410 420 430 440 450 460 pF1KB5 AIRSQYAHYFDLSLVNNGVDETLKKLQEAFDQACSSPQWVPVSWVY :::::::::::::::::::::::::::::::::::::::::::::: NP_002 AIRSQYAHYFDLSLVNNGVDETLKKLQEAFDQACSSPQWVPVSWVY 430 440 450 460 >>NP_001159934 (OMIM: 305360) 55 kDa erythrocyte membran (436 aa) initn: 2856 init1: 2856 opt: 2856 Z-score: 2044.5 bits: 387.5 E(85289): 3.9e-107 Smith-Waterman score: 2856; 100.0% identity (100.0% similar) in 432 aa overlap (35-466:5-436) 10 20 30 40 50 60 pF1KB5 ASEGESGGSMHTALSDLYLEHLLQKRSRPEAVSHPLNTVTEDMYTNGSPAPGSPAQVKGQ :::::::::::::::::::::::::::::: NP_001 MESWAVSHPLNTVTEDMYTNGSPAPGSPAQVKGQ 10 20 30 70 80 90 100 110 120 pF1KB5 EVRKVRLIQFEKVTEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEINGTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVRKVRLIQFEKVTEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEINGTN 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 VTNHSVDQLQKAMKETKGMISLKVIPNQQSRLPALQMFMRAQFDYDPKKDNLIPCKEAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTNHSVDQLQKAMKETKGMISLKVIPNQQSRLPALQMFMRAQFDYDPKKDNLIPCKEAGL 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 KFATGDIIQIINKDDSNWWQGRVEGSSKESAGLIPSPELQEWRVASMAQSAPSEAPSCSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KFATGDIIQIINKDDSNWWQGRVEGSSKESAGLIPSPELQEWRVASMAQSAPSEAPSCSP 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 FGKKKKYKDKYLAKHSSIFDQLDVVSYEEVVRLPAFKRKTLVLIGASGVGRSHIKNALLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGKKKKYKDKYLAKHSSIFDQLDVVSYEEVVRLPAFKRKTLVLIGASGVGRSHIKNALLS 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 QNPEKFVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQGNMFGTKFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNPEKFVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQGNMFGTKFE 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 TVHQIHKQNKIAILDIEPQTLKIVRTAELSPFIVFIAPTDQGTQTEALQQLQKDSEAIRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVHQIHKQNKIAILDIEPQTLKIVRTAELSPFIVFIAPTDQGTQTEALQQLQKDSEAIRS 340 350 360 370 380 390 430 440 450 460 pF1KB5 QYAHYFDLSLVNNGVDETLKKLQEAFDQACSSPQWVPVSWVY :::::::::::::::::::::::::::::::::::::::::: NP_001 QYAHYFDLSLVNNGVDETLKKLQEAFDQACSSPQWVPVSWVY 400 410 420 430 >>NP_001159932 (OMIM: 305360) 55 kDa erythrocyte membran (449 aa) initn: 2542 init1: 2542 opt: 2542 Z-score: 1822.0 bits: 346.4 E(85289): 9.6e-95 Smith-Waterman score: 2922; 96.4% identity (96.4% similar) in 466 aa overlap (1-466:1-449) 10 20 30 40 50 60 pF1KB5 MTLKASEGESGGSMHTALSDLYLEHLLQKRSRPEAVSHPLNTVTEDMYTNGSPAPGSPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTLKASEGESGGSMHTALSDLYLEHLLQKRSRPEAVSHPLNTVTEDMYTNGSPAPGSPAQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VKGQEVRKVRLIQFEKVTEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEI ::::: :::::::::::::::::::::::::::::::::::::: NP_001 VKGQE-----------------GITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEI 70 80 90 100 130 140 150 160 170 180 pF1KB5 NGTNVTNHSVDQLQKAMKETKGMISLKVIPNQQSRLPALQMFMRAQFDYDPKKDNLIPCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGTNVTNHSVDQLQKAMKETKGMISLKVIPNQQSRLPALQMFMRAQFDYDPKKDNLIPCK 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB5 EAGLKFATGDIIQIINKDDSNWWQGRVEGSSKESAGLIPSPELQEWRVASMAQSAPSEAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAGLKFATGDIIQIINKDDSNWWQGRVEGSSKESAGLIPSPELQEWRVASMAQSAPSEAP 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB5 SCSPFGKKKKYKDKYLAKHSSIFDQLDVVSYEEVVRLPAFKRKTLVLIGASGVGRSHIKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SCSPFGKKKKYKDKYLAKHSSIFDQLDVVSYEEVVRLPAFKRKTLVLIGASGVGRSHIKN 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB5 ALLSQNPEKFVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQGNMFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALLSQNPEKFVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQGNMFG 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB5 TKFETVHQIHKQNKIAILDIEPQTLKIVRTAELSPFIVFIAPTDQGTQTEALQQLQKDSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKFETVHQIHKQNKIAILDIEPQTLKIVRTAELSPFIVFIAPTDQGTQTEALQQLQKDSE 350 360 370 380 390 400 430 440 450 460 pF1KB5 AIRSQYAHYFDLSLVNNGVDETLKKLQEAFDQACSSPQWVPVSWVY :::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIRSQYAHYFDLSLVNNGVDETLKKLQEAFDQACSSPQWVPVSWVY 410 420 430 440 >>XP_011529471 (OMIM: 305360) PREDICTED: 55 kDa erythroc (340 aa) initn: 2043 init1: 2043 opt: 2043 Z-score: 1470.0 bits: 280.9 E(85289): 3.9e-75 Smith-Waterman score: 2043; 99.7% identity (100.0% similar) in 307 aa overlap (160-466:34-340) 130 140 150 160 170 180 pF1KB5 VDQLQKAMKETKGMISLKVIPNQQSRLPALQMFMRAQFDYDPKKDNLIPCKEAGLKFATG .::::::::::::::::::::::::::::: XP_011 KASEGESGGSMHTALSDLYLEHLLQKRSRPEMFMRAQFDYDPKKDNLIPCKEAGLKFATG 10 20 30 40 50 60 190 200 210 220 230 240 pF1KB5 DIIQIINKDDSNWWQGRVEGSSKESAGLIPSPELQEWRVASMAQSAPSEAPSCSPFGKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DIIQIINKDDSNWWQGRVEGSSKESAGLIPSPELQEWRVASMAQSAPSEAPSCSPFGKKK 70 80 90 100 110 120 250 260 270 280 290 300 pF1KB5 KYKDKYLAKHSSIFDQLDVVSYEEVVRLPAFKRKTLVLIGASGVGRSHIKNALLSQNPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KYKDKYLAKHSSIFDQLDVVSYEEVVRLPAFKRKTLVLIGASGVGRSHIKNALLSQNPEK 130 140 150 160 170 180 310 320 330 340 350 360 pF1KB5 FVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQGNMFGTKFETVHQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQGNMFGTKFETVHQI 190 200 210 220 230 240 370 380 390 400 410 420 pF1KB5 HKQNKIAILDIEPQTLKIVRTAELSPFIVFIAPTDQGTQTEALQQLQKDSEAIRSQYAHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HKQNKIAILDIEPQTLKIVRTAELSPFIVFIAPTDQGTQTEALQQLQKDSEAIRSQYAHY 250 260 270 280 290 300 430 440 450 460 pF1KB5 FDLSLVNNGVDETLKKLQEAFDQACSSPQWVPVSWVY ::::::::::::::::::::::::::::::::::::: XP_011 FDLSLVNNGVDETLKKLQEAFDQACSSPQWVPVSWVY 310 320 330 340 >>NP_001159933 (OMIM: 305360) 55 kDa erythrocyte membran (446 aa) initn: 1894 init1: 1894 opt: 1903 Z-score: 1369.5 bits: 262.6 E(85289): 1.5e-69 Smith-Waterman score: 2873; 95.7% identity (95.7% similar) in 466 aa overlap (1-466:1-446) 10 20 30 40 50 60 pF1KB5 MTLKASEGESGGSMHTALSDLYLEHLLQKRSRPEAVSHPLNTVTEDMYTNGSPAPGSPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTLKASEGESGGSMHTALSDLYLEHLLQKRSRPEAVSHPLNTVTEDMYTNGSPAPGSPAQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VKGQEVRKVRLIQFEKVTEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKGQEVRKVRLIQFEKVTEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NGTNVTNHSVDQLQKAMKETKGMISLKVIPNQQSRLPALQMFMRAQFDYDPKKDNLIPCK :::::::::::::::::::::::::::::::::::::::: NP_001 NGTNVTNHSVDQLQKAMKETKGMISLKVIPNQQSRLPALQ-------------------- 130 140 150 160 190 200 210 220 230 240 pF1KB5 EAGLKFATGDIIQIINKDDSNWWQGRVEGSSKESAGLIPSPELQEWRVASMAQSAPSEAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAGLKFATGDIIQIINKDDSNWWQGRVEGSSKESAGLIPSPELQEWRVASMAQSAPSEAP 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB5 SCSPFGKKKKYKDKYLAKHSSIFDQLDVVSYEEVVRLPAFKRKTLVLIGASGVGRSHIKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SCSPFGKKKKYKDKYLAKHSSIFDQLDVVSYEEVVRLPAFKRKTLVLIGASGVGRSHIKN 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB5 ALLSQNPEKFVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQGNMFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALLSQNPEKFVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQGNMFG 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB5 TKFETVHQIHKQNKIAILDIEPQTLKIVRTAELSPFIVFIAPTDQGTQTEALQQLQKDSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKFETVHQIHKQNKIAILDIEPQTLKIVRTAELSPFIVFIAPTDQGTQTEALQQLQKDSE 350 360 370 380 390 400 430 440 450 460 pF1KB5 AIRSQYAHYFDLSLVNNGVDETLKKLQEAFDQACSSPQWVPVSWVY :::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIRSQYAHYFDLSLVNNGVDETLKKLQEAFDQACSSPQWVPVSWVY 410 420 430 440 >>XP_006724629 (OMIM: 300172,300422,300749) PREDICTED: p (885 aa) initn: 1535 init1: 802 opt: 1810 Z-score: 1300.2 bits: 250.8 E(85289): 1.1e-65 Smith-Waterman score: 1810; 59.1% identity (87.1% similar) in 425 aa overlap (48-466:461-885) 20 30 40 50 60 70 pF1KB5 LSDLYLEHLLQKRSRPEAVSHPLNTVTEDMYTNGSPAPGSPAQVKGQEVRKVRLIQFEKV : ::. .. ... ..: .:::.::.: XP_006 FMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKN 440 450 460 470 480 490 80 90 100 110 120 130 pF1KB5 TEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEINGTNVTNHSVDQLQKAM :.::::::::.:: . : ::::.:::::::::.::::::: :::: .:.:..:.:::: . XP_006 TDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKML 500 510 520 530 540 550 140 150 160 170 180 190 pF1KB5 KETKGMISLKVIPNQQSRLPALQMFMRAQFDYDPKKDNLIPCKEAGLKFATGDIIQIINK .: .: :..:..:. ... . ....::::.::: ::.::::::::..: .:::::::.: XP_006 REMRGSITFKIVPSYRTQSSSCEIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISK 560 570 580 590 600 610 200 210 220 230 240 250 pF1KB5 DDSNWWQGRVEGSSKESAGLIPSPELQEWRVA--SMAQSAPSEAPSCSPFGKKKK-YKDK :: :::::..:.:.. .::::::::::::::: .: .. . ::. :::::: :::: XP_006 DDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDK 620 630 640 650 660 670 260 270 280 290 300 310 pF1KB5 YLAKHSSIFDQLDVVSYEEVVRLPAFKRKTLVLIGASGVGRSHIKNALLSQNPEKFVYPV :::::...:::::.:.:::::.:::::::::::.:: :::: ::::.:....:..:.::. XP_006 YLAKHNAVFDQLDLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPI 680 690 700 710 720 730 320 330 340 350 360 370 pF1KB5 PYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQGNMFGTKFETVHQIHKQNK :.:::::.:.::.::.:.:.: ..: ..:: ::.::.::.. :.:::.::...::.:. XP_006 PHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGL 740 750 760 770 780 790 380 390 400 410 420 430 pF1KB5 IAILDIEPQTLKIVRTAELSPFIVFIA-PT-DQG-TQTEALQQLQKDSEAIRSQYAHYFD :::::.:::.::..::::..::.:::: :: : .. :.::.:::.:. .. :::::: XP_006 IAILDVEPQALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKESDILQRTYAHYFD 800 810 820 830 840 850 440 450 460 pF1KB5 LSLVNNGVDETLKKLQEAFDQACSSPQWVPVSWVY :...:: .:::...:.:: . .:..:::::::::: XP_006 LTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY 860 870 880 >>XP_011542298 (OMIM: 300172,300422,300749) PREDICTED: p (891 aa) initn: 1535 init1: 802 opt: 1810 Z-score: 1300.1 bits: 250.8 E(85289): 1.1e-65 Smith-Waterman score: 1810; 59.1% identity (87.1% similar) in 425 aa overlap (48-466:467-891) 20 30 40 50 60 70 pF1KB5 LSDLYLEHLLQKRSRPEAVSHPLNTVTEDMYTNGSPAPGSPAQVKGQEVRKVRLIQFEKV : ::. .. ... ..: .:::.::.: XP_011 FMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKN 440 450 460 470 480 490 80 90 100 110 120 130 pF1KB5 TEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEINGTNVTNHSVDQLQKAM :.::::::::.:: . : ::::.:::::::::.::::::: :::: .:.:..:.:::: . XP_011 TDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKML 500 510 520 530 540 550 140 150 160 170 180 190 pF1KB5 KETKGMISLKVIPNQQSRLPALQMFMRAQFDYDPKKDNLIPCKEAGLKFATGDIIQIINK .: .: :..:..:. ... . ....::::.::: ::.::::::::..: .:::::::.: XP_011 REMRGSITFKIVPSYRTQSSSCEIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISK 560 570 580 590 600 610 200 210 220 230 240 250 pF1KB5 DDSNWWQGRVEGSSKESAGLIPSPELQEWRVA--SMAQSAPSEAPSCSPFGKKKK-YKDK :: :::::..:.:.. .::::::::::::::: .: .. . ::. :::::: :::: XP_011 DDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDK 620 630 640 650 660 670 260 270 280 290 300 310 pF1KB5 YLAKHSSIFDQLDVVSYEEVVRLPAFKRKTLVLIGASGVGRSHIKNALLSQNPEKFVYPV :::::...:::::.:.:::::.:::::::::::.:: :::: ::::.:....:..:.::. XP_011 YLAKHNAVFDQLDLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPI 680 690 700 710 720 730 320 330 340 350 360 370 pF1KB5 PYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQGNMFGTKFETVHQIHKQNK :.:::::.:.::.::.:.:.: ..: ..:: ::.::.::.. :.:::.::...::.:. XP_011 PHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGL 740 750 760 770 780 790 380 390 400 410 420 430 pF1KB5 IAILDIEPQTLKIVRTAELSPFIVFIA-PT-DQG-TQTEALQQLQKDSEAIRSQYAHYFD :::::.:::.::..::::..::.:::: :: : .. :.::.:::.:. .. :::::: XP_011 IAILDVEPQALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKESDILQRTYAHYFD 800 810 820 830 840 850 440 450 460 pF1KB5 LSLVNNGVDETLKKLQEAFDQACSSPQWVPVSWVY :...:: .:::...:.:: . .:..:::::::::: XP_011 LTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY 860 870 880 890 >>XP_011529469 (OMIM: 305360) PREDICTED: 55 kDa erythroc (439 aa) initn: 2885 init1: 1729 opt: 1729 Z-score: 1246.3 bits: 239.8 E(85289): 1.1e-62 Smith-Waterman score: 2832; 94.2% identity (94.2% similar) in 466 aa overlap (1-466:1-439) 10 20 30 40 50 60 pF1KB5 MTLKASEGESGGSMHTALSDLYLEHLLQKRSRPEAVSHPLNTVTEDMYTNGSPAPGSPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTLKASEGESGGSMHTALSDLYLEHLLQKRSRPEAVSHPLNTVTEDMYTNGSPAPGSPAQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VKGQEVRKVRLIQFEKVTEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKGQEVRKVRLIQFEKVTEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NGTNVTNHSVDQLQKAMKETKGMISLKVIPNQQSRLPALQMFMRAQFDYDPKKDNLIPCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGTNVTNHSVDQLQKAMKETKGMISLKVIPNQQSRLPALQMFMRAQFDYDPKKDNLIPCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 EAGLKFATGDIIQIINKDDSNWWQGRVEGSSKESAGLIPSPELQEWRVASMAQSAPSEAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAGLKFATGDIIQIINKDDSNWWQGRVEGSSKESAGLIPSPELQEWRVASMAQSAPSEAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SCSPFGKKKKYKDKYLAKHSSIFDQLDVVSYEEVVRLPAFKRKTLVLIGASGVGRSHIKN ::::::::::::::::::::: : ::::::::::: XP_011 SCSPFGKKKKYKDKYLAKHSS--------------R-------------ASGVGRSHIKN 250 260 270 310 320 330 340 350 360 pF1KB5 ALLSQNPEKFVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQGNMFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALLSQNPEKFVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQGNMFG 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 TKFETVHQIHKQNKIAILDIEPQTLKIVRTAELSPFIVFIAPTDQGTQTEALQQLQKDSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKFETVHQIHKQNKIAILDIEPQTLKIVRTAELSPFIVFIAPTDQGTQTEALQQLQKDSE 340 350 360 370 380 390 430 440 450 460 pF1KB5 AIRSQYAHYFDLSLVNNGVDETLKKLQEAFDQACSSPQWVPVSWVY :::::::::::::::::::::::::::::::::::::::::::::: XP_011 AIRSQYAHYFDLSLVNNGVDETLKKLQEAFDQACSSPQWVPVSWVY 400 410 420 430 >>XP_011542299 (OMIM: 300172,300422,300749) PREDICTED: p (735 aa) initn: 1524 init1: 747 opt: 1403 Z-score: 1012.9 bits: 197.4 E(85289): 1.1e-49 Smith-Waterman score: 1748; 55.7% identity (80.7% similar) in 460 aa overlap (48-466:276-735) 20 30 40 50 60 70 pF1KB5 LSDLYLEHLLQKRSRPEAVSHPLNTVTEDMYTNGSPAPGSPAQVKGQEVRKVRLIQFEKV : ::. .. ... ..: .:::.::.: XP_011 FMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKN 250 260 270 280 290 300 80 90 100 110 120 130 pF1KB5 TEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEINGTNVTNHSVDQLQKAM :.::::::::.:: . : ::::.:::::::::.::::::: :::: .:.:..:.:::: . XP_011 TDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKML 310 320 330 340 350 360 140 150 160 pF1KB5 KETKGMISLKVIP-----------------------------NQQSRLPAL------QMF .: .: :..:..: :. : ::. :.. XP_011 REMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVSDLPSTTQPKGRQIY 370 380 390 400 410 420 170 180 190 200 210 220 pF1KB5 MRAQFDYDPKKDNLIPCKEAGLKFATGDIIQIINKDDSNWWQGRVEGSSKESAGLIPSPE .::::.::: ::.::::::::..: .:::::::.::: :::::..:.:.. .:::::::: XP_011 VRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPE 430 440 450 460 470 480 230 240 250 260 270 pF1KB5 LQEWRVA--SMAQSAPSEAPSCSPFGKKKK-YKDKYLAKHSSIFDQLDVVSYEEVVRLPA ::::::: .: .. . ::. :::::: :::::::::...:::::.:.:::::.::: XP_011 LQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNAVFDQLDLVTYEEVVKLPA 490 500 510 520 530 540 280 290 300 310 320 330 pF1KB5 FKRKTLVLIGASGVGRSHIKNALLSQNPEKFVYPVPYTTRPPRKSEEDGKEYHFISTEEM ::::::::.:: :::: ::::.:....:..:.::.:.:::::.:.::.::.:.:.: ..: XP_011 FKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQM 550 560 570 580 590 600 340 350 360 370 380 390 pF1KB5 TRNISANEFLEFGSYQGNMFGTKFETVHQIHKQNKIAILDIEPQTLKIVRTAELSPFIVF ..:: ::.::.::.. :.:::.::...::.:. :::::.:::.::..::::..::.:: XP_011 MQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVF 610 620 630 640 650 660 400 410 420 430 440 450 pF1KB5 IA-PT-DQG-TQTEALQQLQKDSEAIRSQYAHYFDLSLVNNGVDETLKKLQEAFDQACSS :: :: : .. :.::.:::.:. .. :::::::...:: .:::...:.:: . .:.. XP_011 IAAPTITPGLNEDESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTA 670 680 690 700 710 720 460 pF1KB5 PQWVPVSWVY :::::::::: XP_011 PQWVPVSWVY 730 >>NP_001119527 (OMIM: 300172,300422,300749) peripheral p (897 aa) initn: 1531 init1: 747 opt: 1403 Z-score: 1011.9 bits: 197.5 E(85289): 1.3e-49 Smith-Waterman score: 1791; 58.1% identity (85.1% similar) in 437 aa overlap (48-466:461-897) 20 30 40 50 60 70 pF1KB5 LSDLYLEHLLQKRSRPEAVSHPLNTVTEDMYTNGSPAPGSPAQVKGQEVRKVRLIQFEKV : ::. .. ... ..: .:::.::.: NP_001 FMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKN 440 450 460 470 480 490 80 90 100 110 120 130 pF1KB5 TEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEINGTNVTNHSVDQLQKAM :.::::::::.:: . : ::::.:::::::::.::::::: :::: .:.:..:.:::: . NP_001 TDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKML 500 510 520 530 540 550 140 150 160 170 180 pF1KB5 KETKGMISLKVIPNQQSR------LPAL------QMFMRAQFDYDPKKDNLIPCKEAGLK .: .: :..:..:. ... ::. :...::::.::: ::.::::::::.. NP_001 REMRGSITFKIVPSYRTQSSSCEDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIR 560 570 580 590 600 610 190 200 210 220 230 240 pF1KB5 FATGDIIQIINKDDSNWWQGRVEGSSKESAGLIPSPELQEWRVA--SMAQSAPSEAPSCS : .:::::::.::: :::::..:.:.. .::::::::::::::: .: .. . ::. NP_001 FRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCT 620 630 640 650 660 670 250 260 270 280 290 300 pF1KB5 PFGKKKK-YKDKYLAKHSSIFDQLDVVSYEEVVRLPAFKRKTLVLIGASGVGRSHIKNAL :::::: :::::::::...:::::.:.:::::.:::::::::::.:: :::: ::::.: NP_001 WFGKKKKQYKDKYLAKHNAVFDQLDLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTL 680 690 700 710 720 730 310 320 330 340 350 360 pF1KB5 LSQNPEKFVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQGNMFGTK ....:..:.::.:.:::::.:.::.::.:.:.: ..: ..:: ::.::.::.. :.::: NP_001 ITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTK 740 750 760 770 780 790 370 380 390 400 410 pF1KB5 FETVHQIHKQNKIAILDIEPQTLKIVRTAELSPFIVFIA-PT-DQG-TQTEALQQLQKDS .::...::.:. :::::.:::.::..::::..::.:::: :: : .. :.::.:::.: NP_001 LETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKES 800 810 820 830 840 850 420 430 440 450 460 pF1KB5 EAIRSQYAHYFDLSLVNNGVDETLKKLQEAFDQACSSPQWVPVSWVY . .. :::::::...:: .:::...:.:: . .:..:::::::::: NP_001 DILQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY 860 870 880 890 466 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:34:24 2016 done: Fri Nov 4 03:34:25 2016 Total Scan time: 9.750 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]