FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5316, 450 aa 1>>>pF1KB5316 450 - 450 aa - 450 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3589+/-0.00115; mu= 13.0341+/- 0.069 mean_var=90.1847+/-18.036, 0's: 0 Z-trim(103.5): 36 B-trim: 4 in 2/50 Lambda= 0.135054 statistics sampled from 7426 (7446) to 7426 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.587), E-opt: 0.2 (0.229), width: 16 Scan time: 2.710 The best scores are: opt bits E(32554) CCDS45257.1 COPS2 gene_id:9318|Hs108|chr15 ( 450) 2944 584.1 9.8e-167 CCDS32235.1 COPS2 gene_id:9318|Hs108|chr15 ( 443) 2867 569.1 3.2e-162 CCDS11272.1 PSMD11 gene_id:5717|Hs108|chr17 ( 422) 386 85.7 1e-16 >>CCDS45257.1 COPS2 gene_id:9318|Hs108|chr15 (450 aa) initn: 2944 init1: 2944 opt: 2944 Z-score: 3106.9 bits: 584.1 E(32554): 9.8e-167 Smith-Waterman score: 2944; 100.0% identity (100.0% similar) in 450 aa overlap (1-450:1-450) 10 20 30 40 50 60 pF1KB5 MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 EGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYIS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TSKQNSDFLCQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 TSKQNSDFLCQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 QLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 QLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 MGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 FDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 FDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 IRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 IRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDH 370 380 390 400 410 420 430 440 450 pF1KB5 QKRGGARYTALDKWTNQLNSLNQAVVSKLA :::::::::::::::::::::::::::::: CCDS45 QKRGGARYTALDKWTNQLNSLNQAVVSKLA 430 440 450 >>CCDS32235.1 COPS2 gene_id:9318|Hs108|chr15 (443 aa) initn: 2089 init1: 2089 opt: 2867 Z-score: 3026.0 bits: 569.1 E(32554): 3.2e-162 Smith-Waterman score: 2867; 98.4% identity (98.4% similar) in 450 aa overlap (1-450:1-443) 10 20 30 40 50 60 pF1KB5 MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 EGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYIS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TSKQNSDFLCQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILR :::: ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 TSKQ-------MDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILR 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 QLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 QLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLI 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 MGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINP 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 FDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 FDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRN 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB5 IRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 IRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDH 360 370 380 390 400 410 430 440 450 pF1KB5 QKRGGARYTALDKWTNQLNSLNQAVVSKLA :::::::::::::::::::::::::::::: CCDS32 QKRGGARYTALDKWTNQLNSLNQAVVSKLA 420 430 440 >>CCDS11272.1 PSMD11 gene_id:5717|Hs108|chr17 (422 aa) initn: 302 init1: 229 opt: 386 Z-score: 413.8 bits: 85.7 E(32554): 1e-16 Smith-Waterman score: 396; 26.5% identity (57.7% similar) in 388 aa overlap (49-411:4-380) 20 30 40 50 60 70 pF1KB5 EYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKALKQMIKI ::. ::.. : . : .. :....: CCDS11 MAAAAVVEFQRAQSLLSTDREASIDILHSIVKR 10 20 30 80 90 100 110 120 130 pF1KB5 NFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYI-----STSKQNSDFLCQ-- ... : : .. .: . . : .... . ....: :. : :: .. : . CCDS11 DIQ-ENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSL 40 50 60 70 80 90 140 150 160 170 180 pF1KB5 MDLLQEF-------YETTLEALKDAKNDRLWF---KTNTKLGKLYLEREEYGKLQKILRQ .::. .. : :: .. ::... : ...: .::.. ..: . .. : CCDS11 LDLFLDMEAATGQEVELCLECIEWAKSEKRTFLRQALEARLVSLYFDTKRYQEALHLGSQ 100 110 120 130 140 150 190 200 210 220 230 pF1KB5 LHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAI--PHPL : . . : . . :.:. :: . : : .: : .: .. .:: : : CCDS11 LLRELKKMDDK------ALLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCP-PK 160 170 180 190 200 240 250 260 270 280 290 pF1KB5 IMGVIRECGGKMHL-REGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGI ..... .: .: .: ... :.. :.:::..:: ::. : :::..: ...... CCDS11 LQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSPKAITSLKYMLLCKIMLNT-- 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB5 NPFDSQEAKPYK-----NDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREH : : : : . :. ...: .: ....::: : .... :::.: : CCDS11 -PEDVQALVSGKLALRYAGRQTEALKCVAQASKNRSLADFEKALTDYRAELRDDPIISTH 270 280 290 300 310 320 360 370 380 390 400 410 pF1KB5 IEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVN . .: :. : ::..:.:..:..: ::. .... :::: : : :::. .:: .:: CCDS11 LAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGE 330 340 350 360 370 380 420 430 440 450 pF1KB5 QLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA CCDS11 GVLIIFDEPPVDKTYEAALETIQNMSKVVDSLYNKAKKLT 390 400 410 420 450 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:57:43 2016 done: Sat Nov 5 00:57:43 2016 Total Scan time: 2.710 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]