FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5317, 392 aa
1>>>pF1KB5317 392 - 392 aa - 392 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.2516+/-0.000974; mu= 4.0360+/- 0.058
mean_var=171.5508+/-34.387, 0's: 0 Z-trim(110.3): 16 B-trim: 15 in 1/52
Lambda= 0.097921
statistics sampled from 11499 (11506) to 11499 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.353), width: 16
Scan time: 3.260
The best scores are: opt bits E(32554)
CCDS31716.1 FEZ1 gene_id:9638|Hs108|chr11 ( 392) 2551 372.4 3.9e-103
CCDS46258.1 FEZ2 gene_id:9637|Hs108|chr2 ( 380) 917 141.6 1.2e-33
CCDS44758.1 FEZ1 gene_id:9638|Hs108|chr11 ( 104) 695 109.8 1.1e-24
CCDS46257.1 FEZ2 gene_id:9637|Hs108|chr2 ( 353) 499 82.5 6.6e-16
>>CCDS31716.1 FEZ1 gene_id:9638|Hs108|chr11 (392 aa)
initn: 2551 init1: 2551 opt: 2551 Z-score: 1965.1 bits: 372.4 E(32554): 3.9e-103
Smith-Waterman score: 2551; 100.0% identity (100.0% similar) in 392 aa overlap (1-392:1-392)
10 20 30 40 50 60
pF1KB5 MEAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MEAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSME
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 DLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSED
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 WRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 WRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 PEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 PEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQVE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 GAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 GAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SSRIEKGNQMPLKRFSMEGISNILQSGIRQTFGSSGTDKQYLNTVIPYEKKASPPSVEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 SSRIEKGNQMPLKRFSMEGISNILQSGIRQTFGSSGTDKQYLNTVIPYEKKASPPSVEDL
310 320 330 340 350 360
370 380 390
pF1KB5 QMLTNILFAMKEDNEKVPTLLTDYILKVLCPT
::::::::::::::::::::::::::::::::
CCDS31 QMLTNILFAMKEDNEKVPTLLTDYILKVLCPT
370 380 390
>>CCDS46258.1 FEZ2 gene_id:9637|Hs108|chr2 (380 aa)
initn: 734 init1: 437 opt: 917 Z-score: 717.7 bits: 141.6 E(32554): 1.2e-33
Smith-Waterman score: 1047; 52.6% identity (77.2% similar) in 342 aa overlap (66-392:54-380)
40 50 60 70 80 90
pF1KB5 HHLEDPSLSELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQE
..:::..::: . .: : .. ..
CCDS46 ENCNASPEPGAEAGAEAGGGADGFPAPACSLEEKLSLCFRPSDPGAE---PPRTAVRPIT
30 40 50 60 70 80
100 110 120 130 140
pF1KB5 EEETLQDEEVWDALTDNYIPSLSEDWRDPNIEALN--------GNCSDTEIHE-KEEEEF
:. :: .:.:.:::::: . ::.. . ..:. . ::. . . ...::.
CCDS46 ERSLLQGDEIWNALTDNYGNVMPVDWKSSHTRTLHLLTLNLSEKGVSDSLLFDTSDDEEL
90 100 110 120 130 140
150 160 170 180 190 200
pF1KB5 NEKSENDSGI----NEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQAD-
:. . : : :.:::.::::::::::::::.:::::..: : .:.:
CCDS46 REQLDMHSIIVSCVNDEPLFTADQVIEEIEEMMQESPDPEDDE----------TPTQSDR
150 160 170 180 190
210 220 230 240 250 260
pF1KB5 -SVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQVEGAIRDFSEELVQQLARRDEL
:.: ::.:.: .. .... : ....: :::.:.:...: ::...::::::::: ::::
CCDS46 LSMLSQEIQTLKRSSTGSYE-ERVKRLSVSELNEILEEIETAIKEYSEELVQQLALRDEL
200 210 220 230 240
270 280 290 300 310 320
pF1KB5 EFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIEKGNQMPLKRFSMEGI
:::::::::::.:::::::::::..: ::..: :. : :... :. ..:: :::::::
CCDS46 EFEKEVKNSFISVLIEVQNKQKEHKETAKKKKKLKNGSSQNGKNER-SHMPGTRFSMEGI
250 260 270 280 290 300
330 340 350 360 370 380
pF1KB5 SNILQSGIRQTFGSSGTDKQYLNTVIPYEKKASPPSVEDLQMLTNILFAMKEDNEKVPTL
::..:.:.:.:::.:: .::::.:::::::: .::::::::.::.:: :::::.::::.:
CCDS46 SNVIQNGLRHTFGNSGGEKQYLTTVIPYEKKNGPPSVEDLQILTKILRAMKEDSEKVPSL
310 320 330 340 350 360
390
pF1KB5 LTDYILKVLCPT
::::::::::::
CCDS46 LTDYILKVLCPT
370 380
>>CCDS44758.1 FEZ1 gene_id:9638|Hs108|chr11 (104 aa)
initn: 695 init1: 695 opt: 695 Z-score: 556.4 bits: 109.8 E(32554): 1.1e-24
Smith-Waterman score: 695; 100.0% identity (100.0% similar) in 104 aa overlap (1-104:1-104)
10 20 30 40 50 60
pF1KB5 MEAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MEAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSME
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSED
::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEE
70 80 90 100
130 140 150 160 170 180
pF1KB5 WRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPD
>>CCDS46257.1 FEZ2 gene_id:9637|Hs108|chr2 (353 aa)
initn: 888 init1: 320 opt: 499 Z-score: 399.1 bits: 82.5 E(32554): 6.6e-16
Smith-Waterman score: 853; 47.7% identity (70.2% similar) in 342 aa overlap (66-392:54-353)
40 50 60 70 80 90
pF1KB5 HHLEDPSLSELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQE
..:::..::: . .: : .. ..
CCDS46 ENCNASPEPGAEAGAEAGGGADGFPAPACSLEEKLSLCFRPSDPGAE---PPRTAVRPIT
30 40 50 60 70 80
100 110 120 130 140
pF1KB5 EEETLQDEEVWDALTDNYIPSLSEDWRDPNIEALN--------GNCSDTEIHE-KEEEEF
:. :: .:.:.:::::: . ::.. . ..:. . ::. . . ...::.
CCDS46 ERSLLQGDEIWNALTDNYGNVMPVDWKSSHTRTLHLLTLNLSEKGVSDSLLFDTSDDEEL
90 100 110 120 130 140
150 160 170 180 190 200
pF1KB5 NEKSENDSGI----NEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQAD-
:. . : : :.:::.::::::::::::::.:::::..: : .:.:
CCDS46 REQLDMHSIIVSCVNDEPLFTADQVIEEIEEMMQESPDPEDDE----------TPTQSDR
150 160 170 180 190
210 220 230 240 250 260
pF1KB5 -SVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQVEGAIRDFSEELVQQLARRDEL
:.: ::.:.: .. .... : ....: :::.:.:...: ::...::::::::: ::::
CCDS46 LSMLSQEIQTLKRSSTGSYE-ERVKRLSVSELNEILEEIETAIKEYSEELVQQLALRDEL
200 210 220 230 240
270 280 290 300 310 320
pF1KB5 EFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIEKGNQMPLKRFSMEGI
:::::::::::.:::::::::::..: ::..: :. : :... :. ..::
CCDS46 EFEKEVKNSFISVLIEVQNKQKEHKETAKKKKKLKNGSSQNGKNER-SHMP---------
250 260 270 280 290
330 340 350 360 370 380
pF1KB5 SNILQSGIRQTFGSSGTDKQYLNTVIPYEKKASPPSVEDLQMLTNILFAMKEDNEKVPTL
:: ::.:::::::: .::::::::.::.:: :::::.::::.:
CCDS46 ---------------GT---YLTTVIPYEKKNGPPSVEDLQILTKILRAMKEDSEKVPSL
300 310 320 330 340
390
pF1KB5 LTDYILKVLCPT
::::::::::::
CCDS46 LTDYILKVLCPT
350
392 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 21:03:55 2016 done: Sat Nov 5 21:03:55 2016
Total Scan time: 3.260 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]