FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5317, 392 aa 1>>>pF1KB5317 392 - 392 aa - 392 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.2516+/-0.000974; mu= 4.0360+/- 0.058 mean_var=171.5508+/-34.387, 0's: 0 Z-trim(110.3): 16 B-trim: 15 in 1/52 Lambda= 0.097921 statistics sampled from 11499 (11506) to 11499 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.353), width: 16 Scan time: 3.260 The best scores are: opt bits E(32554) CCDS31716.1 FEZ1 gene_id:9638|Hs108|chr11 ( 392) 2551 372.4 3.9e-103 CCDS46258.1 FEZ2 gene_id:9637|Hs108|chr2 ( 380) 917 141.6 1.2e-33 CCDS44758.1 FEZ1 gene_id:9638|Hs108|chr11 ( 104) 695 109.8 1.1e-24 CCDS46257.1 FEZ2 gene_id:9637|Hs108|chr2 ( 353) 499 82.5 6.6e-16 >>CCDS31716.1 FEZ1 gene_id:9638|Hs108|chr11 (392 aa) initn: 2551 init1: 2551 opt: 2551 Z-score: 1965.1 bits: 372.4 E(32554): 3.9e-103 Smith-Waterman score: 2551; 100.0% identity (100.0% similar) in 392 aa overlap (1-392:1-392) 10 20 30 40 50 60 pF1KB5 MEAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MEAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSME 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 DLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSED 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 WRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 WRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 PEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQVE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 GAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 GAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 SSRIEKGNQMPLKRFSMEGISNILQSGIRQTFGSSGTDKQYLNTVIPYEKKASPPSVEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SSRIEKGNQMPLKRFSMEGISNILQSGIRQTFGSSGTDKQYLNTVIPYEKKASPPSVEDL 310 320 330 340 350 360 370 380 390 pF1KB5 QMLTNILFAMKEDNEKVPTLLTDYILKVLCPT :::::::::::::::::::::::::::::::: CCDS31 QMLTNILFAMKEDNEKVPTLLTDYILKVLCPT 370 380 390 >>CCDS46258.1 FEZ2 gene_id:9637|Hs108|chr2 (380 aa) initn: 734 init1: 437 opt: 917 Z-score: 717.7 bits: 141.6 E(32554): 1.2e-33 Smith-Waterman score: 1047; 52.6% identity (77.2% similar) in 342 aa overlap (66-392:54-380) 40 50 60 70 80 90 pF1KB5 HHLEDPSLSELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQE ..:::..::: . .: : .. .. CCDS46 ENCNASPEPGAEAGAEAGGGADGFPAPACSLEEKLSLCFRPSDPGAE---PPRTAVRPIT 30 40 50 60 70 80 100 110 120 130 140 pF1KB5 EEETLQDEEVWDALTDNYIPSLSEDWRDPNIEALN--------GNCSDTEIHE-KEEEEF :. :: .:.:.:::::: . ::.. . ..:. . ::. . . ...::. CCDS46 ERSLLQGDEIWNALTDNYGNVMPVDWKSSHTRTLHLLTLNLSEKGVSDSLLFDTSDDEEL 90 100 110 120 130 140 150 160 170 180 190 200 pF1KB5 NEKSENDSGI----NEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQAD- :. . : : :.:::.::::::::::::::.:::::..: : .:.: CCDS46 REQLDMHSIIVSCVNDEPLFTADQVIEEIEEMMQESPDPEDDE----------TPTQSDR 150 160 170 180 190 210 220 230 240 250 260 pF1KB5 -SVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQVEGAIRDFSEELVQQLARRDEL :.: ::.:.: .. .... : ....: :::.:.:...: ::...::::::::: :::: CCDS46 LSMLSQEIQTLKRSSTGSYE-ERVKRLSVSELNEILEEIETAIKEYSEELVQQLALRDEL 200 210 220 230 240 270 280 290 300 310 320 pF1KB5 EFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIEKGNQMPLKRFSMEGI :::::::::::.:::::::::::..: ::..: :. : :... :. ..:: ::::::: CCDS46 EFEKEVKNSFISVLIEVQNKQKEHKETAKKKKKLKNGSSQNGKNER-SHMPGTRFSMEGI 250 260 270 280 290 300 330 340 350 360 370 380 pF1KB5 SNILQSGIRQTFGSSGTDKQYLNTVIPYEKKASPPSVEDLQMLTNILFAMKEDNEKVPTL ::..:.:.:.:::.:: .::::.:::::::: .::::::::.::.:: :::::.::::.: CCDS46 SNVIQNGLRHTFGNSGGEKQYLTTVIPYEKKNGPPSVEDLQILTKILRAMKEDSEKVPSL 310 320 330 340 350 360 390 pF1KB5 LTDYILKVLCPT :::::::::::: CCDS46 LTDYILKVLCPT 370 380 >>CCDS44758.1 FEZ1 gene_id:9638|Hs108|chr11 (104 aa) initn: 695 init1: 695 opt: 695 Z-score: 556.4 bits: 109.8 E(32554): 1.1e-24 Smith-Waterman score: 695; 100.0% identity (100.0% similar) in 104 aa overlap (1-104:1-104) 10 20 30 40 50 60 pF1KB5 MEAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MEAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSME 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSED :::::::::::::::::::::::::::::::::::::::::::: CCDS44 DLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEE 70 80 90 100 130 140 150 160 170 180 pF1KB5 WRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPD >>CCDS46257.1 FEZ2 gene_id:9637|Hs108|chr2 (353 aa) initn: 888 init1: 320 opt: 499 Z-score: 399.1 bits: 82.5 E(32554): 6.6e-16 Smith-Waterman score: 853; 47.7% identity (70.2% similar) in 342 aa overlap (66-392:54-353) 40 50 60 70 80 90 pF1KB5 HHLEDPSLSELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQE ..:::..::: . .: : .. .. CCDS46 ENCNASPEPGAEAGAEAGGGADGFPAPACSLEEKLSLCFRPSDPGAE---PPRTAVRPIT 30 40 50 60 70 80 100 110 120 130 140 pF1KB5 EEETLQDEEVWDALTDNYIPSLSEDWRDPNIEALN--------GNCSDTEIHE-KEEEEF :. :: .:.:.:::::: . ::.. . ..:. . ::. . . ...::. CCDS46 ERSLLQGDEIWNALTDNYGNVMPVDWKSSHTRTLHLLTLNLSEKGVSDSLLFDTSDDEEL 90 100 110 120 130 140 150 160 170 180 190 200 pF1KB5 NEKSENDSGI----NEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQAD- :. . : : :.:::.::::::::::::::.:::::..: : .:.: CCDS46 REQLDMHSIIVSCVNDEPLFTADQVIEEIEEMMQESPDPEDDE----------TPTQSDR 150 160 170 180 190 210 220 230 240 250 260 pF1KB5 -SVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQVEGAIRDFSEELVQQLARRDEL :.: ::.:.: .. .... : ....: :::.:.:...: ::...::::::::: :::: CCDS46 LSMLSQEIQTLKRSSTGSYE-ERVKRLSVSELNEILEEIETAIKEYSEELVQQLALRDEL 200 210 220 230 240 270 280 290 300 310 320 pF1KB5 EFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIEKGNQMPLKRFSMEGI :::::::::::.:::::::::::..: ::..: :. : :... :. ..:: CCDS46 EFEKEVKNSFISVLIEVQNKQKEHKETAKKKKKLKNGSSQNGKNER-SHMP--------- 250 260 270 280 290 330 340 350 360 370 380 pF1KB5 SNILQSGIRQTFGSSGTDKQYLNTVIPYEKKASPPSVEDLQMLTNILFAMKEDNEKVPTL :: ::.:::::::: .::::::::.::.:: :::::.::::.: CCDS46 ---------------GT---YLTTVIPYEKKNGPPSVEDLQILTKILRAMKEDSEKVPSL 300 310 320 330 340 390 pF1KB5 LTDYILKVLCPT :::::::::::: CCDS46 LTDYILKVLCPT 350 392 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 21:03:55 2016 done: Sat Nov 5 21:03:55 2016 Total Scan time: 3.260 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]