FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5318, 425 aa 1>>>pF1KB5318 425 - 425 aa - 425 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0998+/-0.00116; mu= 7.7438+/- 0.068 mean_var=127.3559+/-26.868, 0's: 0 Z-trim(105.7): 150 B-trim: 66 in 1/50 Lambda= 0.113649 statistics sampled from 8403 (8585) to 8403 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.264), width: 16 Scan time: 2.880 The best scores are: opt bits E(32554) CCDS14179.1 RBBP7 gene_id:5931|Hs108|chrX ( 425) 2930 492.3 3.7e-139 CCDS56598.1 RBBP7 gene_id:5931|Hs108|chrX ( 469) 2897 486.9 1.7e-137 CCDS44105.1 RBBP4 gene_id:5928|Hs108|chr1 ( 424) 2652 446.7 2e-125 CCDS366.1 RBBP4 gene_id:5928|Hs108|chr1 ( 425) 2640 444.8 7.6e-125 CCDS44106.1 RBBP4 gene_id:5928|Hs108|chr1 ( 390) 2451 413.7 1.5e-115 >>CCDS14179.1 RBBP7 gene_id:5931|Hs108|chrX (425 aa) initn: 2930 init1: 2930 opt: 2930 Z-score: 2611.8 bits: 492.3 E(32554): 3.7e-139 Smith-Waterman score: 2930; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:1-425) 10 20 30 40 50 60 pF1KB5 MASKEMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MASKEMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 ALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 NHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 GLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALW 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAED 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSEL 370 380 390 400 410 420 pF1KB5 EGQGS ::::: CCDS14 EGQGS >>CCDS56598.1 RBBP7 gene_id:5931|Hs108|chrX (469 aa) initn: 2897 init1: 2897 opt: 2897 Z-score: 2581.9 bits: 486.9 E(32554): 1.7e-137 Smith-Waterman score: 2897; 99.3% identity (99.8% similar) in 422 aa overlap (4-425:48-469) 10 20 30 pF1KB5 MASKEMFEDTVEERVINEEYKIWKKNTPFLYDL . .::::::::::::::::::::::::::: CCDS56 WRDQACGLLLHVHLSSRLGRAAPVRTGRHLRTVFEDTVEERVINEEYKIWKKNTPFLYDL 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB5 VMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 VMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFD 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB5 ASHCDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 ASHCDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDY 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB5 TKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 TKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEG 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB5 KIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 KIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTA 260 270 280 290 300 310 280 290 300 310 320 330 pF1KB5 EVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 EVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILA 320 330 340 350 360 370 340 350 360 370 380 390 pF1KB5 SSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 SSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVS 380 390 400 410 420 430 400 410 420 pF1KB5 EDNIMQIWQMAENIYNDEESDVTTSELEGQGS :::::::::::::::::::::::::::::::: CCDS56 EDNIMQIWQMAENIYNDEESDVTTSELEGQGS 440 450 460 >>CCDS44105.1 RBBP4 gene_id:5928|Hs108|chr1 (424 aa) initn: 2780 init1: 2633 opt: 2652 Z-score: 2365.4 bits: 446.7 E(32554): 2e-125 Smith-Waterman score: 2652; 89.4% identity (96.7% similar) in 425 aa overlap (1-425:1-424) 10 20 30 40 50 60 pF1KB5 MASKEMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDY ::.:: :.:.:::::::::::::::::::::::::::::.:::::.::::.::.:::::. CCDS44 MADKEAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKI ..: :::::::::::::::.: :..::::::::::: ::.::::::::::.:::: :::: CCDS44 SIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGY :::::::::::::::: ::::::::::::::::::::.:::::::::::::::::::::: CCDS44 NHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 GLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHES ::::: ::::::::::::::.:::::.: :::::.::::.:::::.::::::.::::::: CCDS44 GLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALW :::::::::::::::::::.:::::: ::::::::::::::::::::::::::::::::: CCDS44 LFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALW 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAED ::::::::::.:::::::::::.::::::::::::::::::::::::::::::: ::::: CCDS44 DLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAED 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSEL :::::::::::::::::::::::::::::::::::::::.:::::::::::. . ... CCDS44 GPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP- 370 380 390 400 410 pF1KB5 EGQGS ::::: CCDS44 EGQGS 420 >>CCDS366.1 RBBP4 gene_id:5928|Hs108|chr1 (425 aa) initn: 2739 init1: 2592 opt: 2640 Z-score: 2354.8 bits: 444.8 E(32554): 7.6e-125 Smith-Waterman score: 2640; 89.2% identity (96.5% similar) in 426 aa overlap (1-425:1-425) 10 20 30 40 50 pF1KB5 MASKEM-FEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKD ::.:: :.:.:::::::::::::::::::::::::::::.:::::.::::.::.::::: CCDS36 MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKD 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 YALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIK ...: :::::::::::::::.: :..::::::::::: ::.::::::::::.:::: ::: CCDS36 FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 INHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEG ::::::::::::::::: ::::::::::::::::::::.::::::::::::::::::::: CCDS36 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 YGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHE :::::: ::::::::::::::.:::::.: :::::.::::.:::::.::::::.:::::: CCDS36 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB5 SLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVAL ::::::::::::::::::::.:::::: :::::::::::::::::::::::::::::::: CCDS36 SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVAL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB5 WDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAE :::::::::::.:::::::::::.::::::::::::::::::::::::::::::: :::: CCDS36 WDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB5 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSE ::::::::::::::::::::::::::::::::::::::::.:::::::::::. . ... CCDS36 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP 370 380 390 400 410 420 420 pF1KB5 LEGQGS ::::: CCDS36 -EGQGS >>CCDS44106.1 RBBP4 gene_id:5928|Hs108|chr1 (390 aa) initn: 2579 init1: 2432 opt: 2451 Z-score: 2187.9 bits: 413.7 E(32554): 1.5e-115 Smith-Waterman score: 2451; 89.5% identity (96.7% similar) in 391 aa overlap (35-425:1-390) 10 20 30 40 50 60 pF1KB5 EMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDYALHW :::::.:::::.::::.::.:::::...: CCDS44 MTHALEWPSLTAQWLPDVTRPEGKDFSIHR 10 20 30 70 80 90 100 110 120 pF1KB5 LVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKINHEG :::::::::::::::.: :..::::::::::: ::.::::::::::.:::: :::::::: CCDS44 LVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEG 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 EVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSW :::::::::::: ::::::::::::::::::::.:::::::::::::::::::::::::: CCDS44 EVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSW 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 NSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGS : ::::::::::::::.:::::.: :::::.::::.:::::.::::::.::::::::::: CCDS44 NPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGS 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 VADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN :::::::::::::::.:::::: ::::::::::::::::::::::::::::::::::::: CCDS44 VADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 LKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPE ::::::.:::::::::::.::::::::::::::::::::::::::::::: ::::::::: CCDS44 LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPE 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 LLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSELEGQG :::::::::::::::::::::::::::::::::::.:::::::::::. . ... :::: CCDS44 LLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP-EGQG 340 350 360 370 380 pF1KB5 S : CCDS44 S 390 425 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:35:06 2016 done: Fri Nov 4 03:35:07 2016 Total Scan time: 2.880 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]