FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5318, 425 aa 1>>>pF1KB5318 425 - 425 aa - 425 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5873+/-0.000517; mu= 11.0827+/- 0.031 mean_var=178.8069+/-39.845, 0's: 0 Z-trim(112.5): 251 B-trim: 306 in 1/51 Lambda= 0.095914 statistics sampled from 21160 (21491) to 21160 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.619), E-opt: 0.2 (0.252), width: 16 Scan time: 8.740 The best scores are: opt bits E(85289) NP_002884 (OMIM: 300825) histone-binding protein R ( 425) 2930 418.7 1.4e-116 NP_001185648 (OMIM: 300825) histone-binding protei ( 469) 2897 414.2 3.6e-115 NP_001128727 (OMIM: 602923) histone-binding protei ( 424) 2652 380.2 5.4e-105 NP_005601 (OMIM: 602923) histone-binding protein R ( 425) 2640 378.5 1.7e-104 NP_001128728 (OMIM: 602923) histone-binding protei ( 390) 2451 352.3 1.2e-96 XP_005267076 (OMIM: 215100,266500,601757,614879) P ( 285) 253 48.0 3.6e-05 NP_000279 (OMIM: 215100,266500,601757,614879) pero ( 323) 253 48.1 3.9e-05 NP_001177386 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 246 47.3 9.7e-05 NP_001310944 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 246 47.3 9.7e-05 NP_001310943 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 246 47.3 9.7e-05 NP_001177385 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 246 47.3 9.7e-05 NP_006082 (OMIM: 605002) coronin-2B isoform 1 [Hom ( 480) 246 47.3 9.8e-05 XP_011517288 (OMIM: 602159) PREDICTED: coronin-2A ( 525) 245 47.2 0.00011 NP_438171 (OMIM: 602159) coronin-2A [Homo sapiens] ( 525) 245 47.2 0.00011 NP_003380 (OMIM: 602159) coronin-2A [Homo sapiens] ( 525) 245 47.2 0.00011 XP_011509771 (OMIM: 616620) PREDICTED: ribosome bi ( 285) 232 45.1 0.00027 NP_060726 (OMIM: 616620) ribosome biogenesis prote ( 423) 232 45.3 0.00035 NP_942590 (OMIM: 608141) nucleoporin Nup43 [Homo s ( 380) 226 44.4 0.00057 NP_006089 (OMIM: 176981) receptor of activated pro ( 317) 223 43.9 0.00068 NP_008882 (OMIM: 601787) transcription initiation ( 800) 227 45.0 0.00084 XP_005267019 (OMIM: 608141) PREDICTED: nucleoporin ( 313) 220 43.5 0.0009 XP_011534101 (OMIM: 608141) PREDICTED: nucleoporin ( 317) 220 43.5 0.00091 XP_005267018 (OMIM: 608141) PREDICTED: nucleoporin ( 333) 220 43.5 0.00094 XP_005267017 (OMIM: 608141) PREDICTED: nucleoporin ( 333) 220 43.5 0.00094 XP_011534100 (OMIM: 608141) PREDICTED: nucleoporin ( 347) 220 43.6 0.00096 NP_001307813 (OMIM: 603331) cytoplasmic dynein 1 i ( 611) 223 44.3 0.001 NP_001258719 (OMIM: 603331) cytoplasmic dynein 1 i ( 611) 223 44.3 0.001 NP_001258718 (OMIM: 603331) cytoplasmic dynein 1 i ( 612) 223 44.3 0.001 NP_001258717 (OMIM: 603331) cytoplasmic dynein 1 i ( 612) 223 44.3 0.001 NP_001258715 (OMIM: 603331) cytoplasmic dynein 1 i ( 630) 223 44.3 0.0011 NP_001258716 (OMIM: 603331) cytoplasmic dynein 1 i ( 630) 223 44.3 0.0011 XP_016859014 (OMIM: 603331) PREDICTED: cytoplasmic ( 631) 223 44.3 0.0011 XP_006712410 (OMIM: 603331) PREDICTED: cytoplasmic ( 631) 223 44.3 0.0011 NP_001307812 (OMIM: 603331) cytoplasmic dynein 1 i ( 632) 223 44.3 0.0011 NP_001307811 (OMIM: 603331) cytoplasmic dynein 1 i ( 632) 223 44.3 0.0011 NP_001258714 (OMIM: 603331) cytoplasmic dynein 1 i ( 638) 223 44.3 0.0011 NP_001369 (OMIM: 603331) cytoplasmic dynein 1 inte ( 638) 223 44.3 0.0011 NP_001308124 (OMIM: 270710,602342,608628,616944) F ( 427) 219 43.5 0.0012 NP_113673 (OMIM: 610597) glutamate-rich WD repeat- ( 446) 219 43.6 0.0012 NP_001308123 (OMIM: 270710,602342,608628,616944) F ( 514) 219 43.6 0.0014 NP_078941 (OMIM: 270710,602342,608628,616944) F-bo ( 514) 219 43.6 0.0014 XP_011511445 (OMIM: 270710,602342,608628,616944) P ( 514) 219 43.6 0.0014 XP_011511443 (OMIM: 270710,602342,608628,616944) P ( 514) 219 43.6 0.0014 NP_001308122 (OMIM: 270710,602342,608628,616944) F ( 514) 219 43.6 0.0014 XP_006713809 (OMIM: 270710,602342,608628,616944) P ( 514) 219 43.6 0.0014 XP_011511444 (OMIM: 270710,602342,608628,616944) P ( 514) 219 43.6 0.0014 XP_016862674 (OMIM: 270710,602342,608628,616944) P ( 514) 219 43.6 0.0014 XP_005247832 (OMIM: 270710,602342,608628,616944) P ( 514) 219 43.6 0.0014 NP_620640 (OMIM: 601787) transcription initiation ( 745) 220 44.0 0.0016 NP_001188402 (OMIM: 611668) coronin-7 isoform 3 [H ( 840) 220 44.0 0.0017 >>NP_002884 (OMIM: 300825) histone-binding protein RBBP7 (425 aa) initn: 2930 init1: 2930 opt: 2930 Z-score: 2213.8 bits: 418.7 E(85289): 1.4e-116 Smith-Waterman score: 2930; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:1-425) 10 20 30 40 50 60 pF1KB5 MASKEMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MASKEMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 GLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALW 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAED 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSEL 370 380 390 400 410 420 pF1KB5 EGQGS ::::: NP_002 EGQGS >>NP_001185648 (OMIM: 300825) histone-binding protein RB (469 aa) initn: 2897 init1: 2897 opt: 2897 Z-score: 2188.6 bits: 414.2 E(85289): 3.6e-115 Smith-Waterman score: 2897; 99.3% identity (99.8% similar) in 422 aa overlap (4-425:48-469) 10 20 30 pF1KB5 MASKEMFEDTVEERVINEEYKIWKKNTPFLYDL . .::::::::::::::::::::::::::: NP_001 WRDQACGLLLHVHLSSRLGRAAPVRTGRHLRTVFEDTVEERVINEEYKIWKKNTPFLYDL 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB5 VMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFD 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB5 ASHCDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASHCDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDY 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB5 TKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEG 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB5 KIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTA 260 270 280 290 300 310 280 290 300 310 320 330 pF1KB5 EVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILA 320 330 340 350 360 370 340 350 360 370 380 390 pF1KB5 SSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVS 380 390 400 410 420 430 400 410 420 pF1KB5 EDNIMQIWQMAENIYNDEESDVTTSELEGQGS :::::::::::::::::::::::::::::::: NP_001 EDNIMQIWQMAENIYNDEESDVTTSELEGQGS 440 450 460 >>NP_001128727 (OMIM: 602923) histone-binding protein RB (424 aa) initn: 2780 init1: 2633 opt: 2652 Z-score: 2005.9 bits: 380.2 E(85289): 5.4e-105 Smith-Waterman score: 2652; 89.4% identity (96.7% similar) in 425 aa overlap (1-425:1-424) 10 20 30 40 50 60 pF1KB5 MASKEMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDY ::.:: :.:.:::::::::::::::::::::::::::::.:::::.::::.::.:::::. NP_001 MADKEAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKI ..: :::::::::::::::.: :..::::::::::: ::.::::::::::.:::: :::: NP_001 SIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGY :::::::::::::::: ::::::::::::::::::::.:::::::::::::::::::::: NP_001 NHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 GLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHES ::::: ::::::::::::::.:::::.: :::::.::::.:::::.::::::.::::::: NP_001 GLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALW :::::::::::::::::::.:::::: ::::::::::::::::::::::::::::::::: NP_001 LFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALW 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAED ::::::::::.:::::::::::.::::::::::::::::::::::::::::::: ::::: NP_001 DLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAED 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSEL :::::::::::::::::::::::::::::::::::::::.:::::::::::. . ... NP_001 GPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP- 370 380 390 400 410 pF1KB5 EGQGS ::::: NP_001 EGQGS 420 >>NP_005601 (OMIM: 602923) histone-binding protein RBBP4 (425 aa) initn: 2739 init1: 2592 opt: 2640 Z-score: 1996.9 bits: 378.5 E(85289): 1.7e-104 Smith-Waterman score: 2640; 89.2% identity (96.5% similar) in 426 aa overlap (1-425:1-425) 10 20 30 40 50 pF1KB5 MASKEM-FEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKD ::.:: :.:.:::::::::::::::::::::::::::::.:::::.::::.::.::::: NP_005 MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKD 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 YALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIK ...: :::::::::::::::.: :..::::::::::: ::.::::::::::.:::: ::: NP_005 FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 INHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEG ::::::::::::::::: ::::::::::::::::::::.::::::::::::::::::::: NP_005 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 YGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHE :::::: ::::::::::::::.:::::.: :::::.::::.:::::.::::::.:::::: NP_005 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB5 SLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVAL ::::::::::::::::::::.:::::: :::::::::::::::::::::::::::::::: NP_005 SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVAL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB5 WDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAE :::::::::::.:::::::::::.::::::::::::::::::::::::::::::: :::: NP_005 WDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB5 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSE ::::::::::::::::::::::::::::::::::::::::.:::::::::::. . ... NP_005 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP 370 380 390 400 410 420 420 pF1KB5 LEGQGS ::::: NP_005 -EGQGS >>NP_001128728 (OMIM: 602923) histone-binding protein RB (390 aa) initn: 2579 init1: 2432 opt: 2451 Z-score: 1856.0 bits: 352.3 E(85289): 1.2e-96 Smith-Waterman score: 2451; 89.5% identity (96.7% similar) in 391 aa overlap (35-425:1-390) 10 20 30 40 50 60 pF1KB5 EMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDYALHW :::::.:::::.::::.::.:::::...: NP_001 MTHALEWPSLTAQWLPDVTRPEGKDFSIHR 10 20 30 70 80 90 100 110 120 pF1KB5 LVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKINHEG :::::::::::::::.: :..::::::::::: ::.::::::::::.:::: :::::::: NP_001 LVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEG 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 EVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSW :::::::::::: ::::::::::::::::::::.:::::::::::::::::::::::::: NP_001 EVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSW 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 NSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGS : ::::::::::::::.:::::.: :::::.::::.:::::.::::::.::::::::::: NP_001 NPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGS 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 VADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN :::::::::::::::.:::::: ::::::::::::::::::::::::::::::::::::: NP_001 VADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 LKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPE ::::::.:::::::::::.::::::::::::::::::::::::::::::: ::::::::: NP_001 LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPE 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 LLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSELEGQG :::::::::::::::::::::::::::::::::::.:::::::::::. . ... :::: NP_001 LLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP-EGQG 340 350 360 370 380 pF1KB5 S : NP_001 S 390 >>XP_005267076 (OMIM: 215100,266500,601757,614879) PREDI (285 aa) initn: 352 init1: 176 opt: 253 Z-score: 213.8 bits: 48.0 E(85289): 3.6e-05 Smith-Waterman score: 312; 27.2% identity (56.8% similar) in 250 aa overlap (135-382:41-270) 110 120 130 140 150 160 pF1KB5 GGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSG : :.. : . .... ..: .: XP_005 LILDPDEAGLRLFRSFDWNDGLFDVTWSENNEHVLITCSGDGSLQLWDTAK--------- 20 30 40 50 60 170 180 190 200 210 220 pF1KB5 ECNPDLRLRGHQKEGYGLSWNSNLSGHLL-SASDDHTVCLWDINAGPKEGKIVDAKAIFT .: . : .: :...:... . .:. :.: :.:: ::: : :: . : XP_005 AAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWD----PTVGKSL---CTFR 70 80 90 100 110 230 240 250 260 270 280 pF1KB5 GHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPY :: ... .. : . :.:.. :: : :::... . .. :: ::. .. : XP_005 GHESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAGVRI---VIPAHQAEILSCDWCKY 120 130 140 150 160 170 290 300 310 320 330 340 pF1KB5 SEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNV .: .:.::..: .. :::::.. . . .: : .:..:: . ..::: . : . XP_005 NENLLVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRF 180 190 200 210 220 230 350 360 370 380 390 400 pF1KB5 WDLSKIGEE-QSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQ :..:: ...: . : : . : ...: ::. XP_005 WNFSKPDSLLETVEHHTEFTCGLDFSLQSPT-QVADCSWDETIKIYDPACLTIPA 240 250 260 270 280 410 420 pF1KB5 MAENIYNDEESDVTTSELEGQGS >>NP_000279 (OMIM: 215100,266500,601757,614879) peroxiso (323 aa) initn: 269 init1: 176 opt: 253 Z-score: 213.2 bits: 48.1 E(85289): 3.9e-05 Smith-Waterman score: 312; 27.2% identity (56.8% similar) in 250 aa overlap (135-382:79-308) 110 120 130 140 150 160 pF1KB5 GGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSG : :.. : . .... ..: .: NP_000 LILDPDEAGLRLFRSFDWNDGLFDVTWSENNEHVLITCSGDGSLQLWDTAK--------- 50 60 70 80 90 170 180 190 200 210 220 pF1KB5 ECNPDLRLRGHQKEGYGLSWNSNLSGHLL-SASDDHTVCLWDINAGPKEGKIVDAKAIFT .: . : .: :...:... . .:. :.: :.:: ::: : :: . : NP_000 AAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWD----PTVGKSL---CTFR 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB5 GHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPY :: ... .. : . :.:.. :: : :::... . .. :: ::. .. : NP_000 GHESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAGVRI---VIPAHQAEILSCDWCKY 160 170 180 190 200 290 300 310 320 330 340 pF1KB5 SEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNV .: .:.::..: .. :::::.. . . .: : .:..:: . ..::: . : . NP_000 NENLLVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRF 210 220 230 240 250 260 350 360 370 380 390 400 pF1KB5 WDLSKIGEE-QSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQ :..:: ...: . : : . : ...: ::. NP_000 WNFSKPDSLLETVEHHTEFTCGLDFSLQSPT-QVADCSWDETIKIYDPACLTIPA 270 280 290 300 310 320 410 420 pF1KB5 MAENIYNDEESDVTTSELEGQGS >>NP_001177386 (OMIM: 605002) coronin-2B isoform 2 [Homo (475 aa) initn: 258 init1: 154 opt: 246 Z-score: 206.1 bits: 47.3 E(85289): 9.7e-05 Smith-Waterman score: 246; 24.2% identity (55.5% similar) in 265 aa overlap (107-367:16-270) 80 90 100 110 120 130 pF1KB5 HLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNP .:.:... .: : .:. .. : NP_001 MSWRPQYRSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNT 10 20 30 40 140 150 160 170 180 190 pF1KB5 HIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDL-RLRGHQKEGYGLSWNSNLSGHLLSA ...: : :. : : . .:. .:. .. ::: . ..:: ... . : NP_001 RFLAIVTESAGGGSFLVI--PL--EQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASC 50 60 70 80 90 100 200 210 220 230 240 250 pF1KB5 SDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWD :.: .: .:.: : . ....: . ::: : : :: .... :.. : :..::. NP_001 SEDTSVRIWEIPEGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWN 110 120 130 140 150 160 260 270 280 290 300 310 pF1KB5 TRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESH ...: ...: :: . :.::: . .:.: :: . . . :. .. :. . . NP_001 L---DVGEPVKMIDCHTDVILCMSFNTDGS-LLTTTCKDKKLRVIEPRSGRV-LQEANCK 170 180 190 200 210 320 330 340 350 360 370 pF1KB5 KDEIFQVHWSPHNETILA---SSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGH . .. .: . . . .:. : . :.. .:: .. :. :: ::: NP_001 NHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPLIEEEI-DGLSGLLFPFYDA 220 230 240 250 260 270 380 390 400 410 420 pF1KB5 TAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSELEGQGS NP_001 DTHMLYLAGKGDGNIRYYEISTEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRF 280 290 300 310 320 330 >>NP_001310944 (OMIM: 605002) coronin-2B isoform 2 [Homo (475 aa) initn: 258 init1: 154 opt: 246 Z-score: 206.1 bits: 47.3 E(85289): 9.7e-05 Smith-Waterman score: 246; 24.2% identity (55.5% similar) in 265 aa overlap (107-367:16-270) 80 90 100 110 120 130 pF1KB5 HLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNP .:.:... .: : .:. .. : NP_001 MSWRPQYRSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNT 10 20 30 40 140 150 160 170 180 190 pF1KB5 HIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDL-RLRGHQKEGYGLSWNSNLSGHLLSA ...: : :. : : . .:. .:. .. ::: . ..:: ... . : NP_001 RFLAIVTESAGGGSFLVI--PL--EQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASC 50 60 70 80 90 100 200 210 220 230 240 250 pF1KB5 SDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWD :.: .: .:.: : . ....: . ::: : : :: .... :.. : :..::. NP_001 SEDTSVRIWEIPEGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWN 110 120 130 140 150 160 260 270 280 290 300 310 pF1KB5 TRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESH ...: ...: :: . :.::: . .:.: :: . . . :. .. :. . . NP_001 L---DVGEPVKMIDCHTDVILCMSFNTDGS-LLTTTCKDKKLRVIEPRSGRV-LQEANCK 170 180 190 200 210 320 330 340 350 360 370 pF1KB5 KDEIFQVHWSPHNETILA---SSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGH . .. .: . . . .:. : . :.. .:: .. :. :: ::: NP_001 NHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPLIEEEI-DGLSGLLFPFYDA 220 230 240 250 260 270 380 390 400 410 420 pF1KB5 TAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSELEGQGS NP_001 DTHMLYLAGKGDGNIRYYEISTEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRF 280 290 300 310 320 330 >>NP_001310943 (OMIM: 605002) coronin-2B isoform 2 [Homo (475 aa) initn: 258 init1: 154 opt: 246 Z-score: 206.1 bits: 47.3 E(85289): 9.7e-05 Smith-Waterman score: 246; 24.2% identity (55.5% similar) in 265 aa overlap (107-367:16-270) 80 90 100 110 120 130 pF1KB5 HLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNP .:.:... .: : .:. .. : NP_001 MSWRPQYRSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNT 10 20 30 40 140 150 160 170 180 190 pF1KB5 HIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDL-RLRGHQKEGYGLSWNSNLSGHLLSA ...: : :. : : . .:. .:. .. ::: . ..:: ... . : NP_001 RFLAIVTESAGGGSFLVI--PL--EQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASC 50 60 70 80 90 100 200 210 220 230 240 250 pF1KB5 SDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWD :.: .: .:.: : . ....: . ::: : : :: .... :.. : :..::. NP_001 SEDTSVRIWEIPEGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWN 110 120 130 140 150 160 260 270 280 290 300 310 pF1KB5 TRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESH ...: ...: :: . :.::: . .:.: :: . . . :. .. :. . . NP_001 L---DVGEPVKMIDCHTDVILCMSFNTDGS-LLTTTCKDKKLRVIEPRSGRV-LQEANCK 170 180 190 200 210 320 330 340 350 360 370 pF1KB5 KDEIFQVHWSPHNETILA---SSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGH . .. .: . . . .:. : . :.. .:: .. :. :: ::: NP_001 NHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPLIEEEI-DGLSGLLFPFYDA 220 230 240 250 260 270 380 390 400 410 420 pF1KB5 TAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSELEGQGS NP_001 DTHMLYLAGKGDGNIRYYEISTEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRF 280 290 300 310 320 330 425 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:35:07 2016 done: Fri Nov 4 03:35:08 2016 Total Scan time: 8.740 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]