FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5326, 450 aa 1>>>pF1KB5326 450 - 450 aa - 450 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3605+/-0.00093; mu= 12.7824+/- 0.056 mean_var=88.1153+/-17.618, 0's: 0 Z-trim(107.6): 35 B-trim: 262 in 1/50 Lambda= 0.136631 statistics sampled from 9647 (9678) to 9647 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.652), E-opt: 0.2 (0.297), width: 16 Scan time: 2.870 The best scores are: opt bits E(32554) CCDS3032.1 SNX4 gene_id:8723|Hs108|chr3 ( 450) 2981 597.6 8.2e-171 CCDS43865.1 SNX30 gene_id:401548|Hs108|chr9 ( 437) 356 80.2 4.6e-15 CCDS755.2 SNX7 gene_id:51375|Hs108|chr1 ( 451) 330 75.1 1.7e-13 >>CCDS3032.1 SNX4 gene_id:8723|Hs108|chr3 (450 aa) initn: 2981 init1: 2981 opt: 2981 Z-score: 3180.1 bits: 597.6 E(32554): 8.2e-171 Smith-Waterman score: 2981; 100.0% identity (100.0% similar) in 450 aa overlap (1-450:1-450) 10 20 30 40 50 60 pF1KB5 MEQAPPDPERQLQPAPLEPLGSPDAGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 MEQAPPDPERQLQPAPLEPLGSPDAGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 SVSEAEKRTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 SVSEAEKRTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 YPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 YPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTDLKHYSDELQSVISHLLRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 LTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTDLKHYSDELQSVISHLLRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 RARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILEDEEHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 RARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILEDEEHY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 ADQLKEYLFYAEALRAVCRKHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 ADQLKEYLFYAEALRAVCRKHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 KLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 KLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKE 370 380 390 400 410 420 430 440 450 pF1KB5 ALISYAVMQISMCKKGIQVWTNAKECFSKM :::::::::::::::::::::::::::::: CCDS30 ALISYAVMQISMCKKGIQVWTNAKECFSKM 430 440 450 >>CCDS43865.1 SNX30 gene_id:401548|Hs108|chr9 (437 aa) initn: 259 init1: 171 opt: 356 Z-score: 383.9 bits: 80.2 E(32554): 4.6e-15 Smith-Waterman score: 356; 28.5% identity (61.0% similar) in 267 aa overlap (78-340:106-363) 50 60 70 80 90 100 pF1KB5 MTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTD-SLWRR ::: .: : :.: : . : . :. :: CCDS43 NRLQLDDDIDGETRDLFVIVDDPKKHVCTMETYITYRITTKS---TRVEFDLPEYSVRRR 80 90 100 110 120 130 110 120 130 140 150 160 pF1KB5 YSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIA :..:. ::: : : ..:::::: :: : .: .. .::: :: .:..:: ::. CCDS43 YQDFDWLRSKLEESQPTHLIPPLPEK---FVV-KGVVDRFSEEFVETRRKALDKFLKRIT 140 150 160 170 180 170 180 190 200 210 220 pF1KB5 SHPILCRDKIFYLFLTQEGNWKETVNETGFQL--KADSRLKALNATFRVKNPDKRFTDLK .::.: .. : .::: . .. .. :. : . .: ... ..... .:. . CCDS43 DHPVLSFNEHFNIFLTAKD--LNAYKKQGIALLTRMGESVKHVTGGYKLRTRPLEFAAIG 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB5 HYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMD : : . .. . :. :. . .:: :.: :::.: :... :.... . CCDS43 DYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIG 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB5 VYASSIDDILED-EEHYADQLKEYLFYAEALRAVCRKHELMQYDLEMAAQDLASKKQQCE ....... .: : . :.::..:......: .:.. .: . : . .: .:. CCDS43 NCSTALEELTDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYEAKLEAVALRKEDRP 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB5 ELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFVKNA CCDS43 KVPADVEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCLMAWESI 370 380 390 400 410 420 >>CCDS755.2 SNX7 gene_id:51375|Hs108|chr1 (451 aa) initn: 241 init1: 113 opt: 330 Z-score: 356.0 bits: 75.1 E(32554): 1.7e-13 Smith-Waterman score: 339; 25.7% identity (60.5% similar) in 296 aa overlap (55-345:93-376) 30 40 50 60 70 80 pF1KB5 AGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYL :: . :.:.: :.. .. ::. .: CCDS75 SLMDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESH-----VTTIETFITYR 70 80 90 100 110 90 100 110 120 130 140 pF1KB5 IETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSAD : :.. . .: . . :::..: :.. : .: ...:::::: :. . . .. CCDS75 IITKTSRGEFDSSEF--EVRRRYQDFLWLKGKLEEAHPTLIIPPLPEK---FIVKGM-VE 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB5 NMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET---GFQLKAD .. ::.: :: .:..:: :::.:: : .. : .::: .. :. . .. :. . CCDS75 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQA-WELSSHKKQGPGLLSRMG 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB5 SRLKALNATFR-VKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGR . ..:. ...: ::: ..: ..... . ... :. . .. :. . . .:: CCDS75 QTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGP 240 250 260 270 280 290 270 280 290 300 310 pF1KB5 VFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALRAVCR . ::: :... : :.... .: .. . . : ..::..:.: : .: . CCDS75 IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMK 300 310 320 330 340 350 320 330 340 350 360 370 pF1KB5 KHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLE ... .: .:. .. :. :: . . : CCDS75 RRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIK 360 370 380 390 400 410 450 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 12:28:22 2016 done: Sat Nov 5 12:28:23 2016 Total Scan time: 2.870 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]