Result of FASTA (omim) for pF1KB5326
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5326, 450 aa
  1>>>pF1KB5326 450 - 450 aa - 450 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.2480+/-0.000398; mu= 13.8227+/- 0.025
 mean_var=97.8031+/-19.576, 0's: 0 Z-trim(114.9): 52  B-trim: 1014 in 2/54
 Lambda= 0.129687
 statistics sampled from 24905 (24957) to 24905 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.293), width:  16
 Scan time:  9.100

The best scores are:                                      opt bits E(85289)
NP_003785 (OMIM: 605931) sorting nexin-4 [Homo sap ( 450) 2981 568.2 1.5e-161
XP_016862903 (OMIM: 605931) PREDICTED: sorting nex ( 482) 1755 338.9 1.8e-92
XP_016856917 (OMIM: 614904) PREDICTED: sorting nex ( 336)  333 72.7 1.6e-12
XP_006710740 (OMIM: 614904) PREDICTED: sorting nex ( 422)  333 72.8   2e-12
XP_006710741 (OMIM: 614904) PREDICTED: sorting nex ( 387)  330 72.2 2.7e-12
XP_016856916 (OMIM: 614904) PREDICTED: sorting nex ( 387)  330 72.2 2.7e-12
XP_016856915 (OMIM: 614904) PREDICTED: sorting nex ( 387)  330 72.2 2.7e-12
XP_011539866 (OMIM: 614904) PREDICTED: sorting nex ( 387)  330 72.2 2.7e-12
XP_016856914 (OMIM: 614904) PREDICTED: sorting nex ( 387)  330 72.2 2.7e-12
NP_057060 (OMIM: 614904) sorting nexin-7 isoform a ( 451)  330 72.2 3.1e-12
NP_001265128 (OMIM: 605929) sorting nexin-2 isofor ( 402)  218 51.3 5.7e-06
NP_003091 (OMIM: 605929) sorting nexin-2 isoform 1 ( 519)  218 51.3   7e-06
NP_001287858 (OMIM: 605930) sorting nexin-3 isofor ( 140)  187 45.2 0.00014
NP_003786 (OMIM: 605930) sorting nexin-3 isoform a ( 162)  187 45.2 0.00015
NP_001243117 (OMIM: 300883) sorting nexin-12 isofo ( 158)  171 42.2  0.0012
NP_037478 (OMIM: 300883) sorting nexin-12 isoform  ( 162)  171 42.2  0.0012
NP_001243114 (OMIM: 300883) sorting nexin-12 isofo ( 162)  171 42.2  0.0012


>>NP_003785 (OMIM: 605931) sorting nexin-4 [Homo sapiens  (450 aa)
 initn: 2981 init1: 2981 opt: 2981  Z-score: 3021.3  bits: 568.2 E(85289): 1.5e-161
Smith-Waterman score: 2981; 100.0% identity (100.0% similar) in 450 aa overlap (1-450:1-450)

               10        20        30        40        50        60
pF1KB5 MEQAPPDPERQLQPAPLEPLGSPDAGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MEQAPPDPERQLQPAPLEPLGSPDAGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 SVSEAEKRTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SVSEAEKRTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 YPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 LTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTDLKHYSDELQSVISHLLRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTDLKHYSDELQSVISHLLRV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 RARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILEDEEHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILEDEEHY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 ADQLKEYLFYAEALRAVCRKHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ADQLKEYLFYAEALRAVCRKHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 KLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKE
              370       380       390       400       410       420

              430       440       450
pF1KB5 ALISYAVMQISMCKKGIQVWTNAKECFSKM
       ::::::::::::::::::::::::::::::
NP_003 ALISYAVMQISMCKKGIQVWTNAKECFSKM
              430       440       450

>>XP_016862903 (OMIM: 605931) PREDICTED: sorting nexin-4  (482 aa)
 initn: 2967 init1: 1748 opt: 1755  Z-score: 1781.2  bits: 338.9 E(85289): 1.8e-92
Smith-Waterman score: 2907; 93.4% identity (93.4% similar) in 482 aa overlap (1-450:1-482)

               10        20        30        40        50        60
pF1KB5 MEQAPPDPERQLQPAPLEPLGSPDAGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEQAPPDPERQLQPAPLEPLGSPDAGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 SVSEAEKRTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVSEAEKRTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 YPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 LTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTDLKHYSDELQSVISHLLRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTDLKHYSDELQSVISHLLRV
              190       200       210       220       230       240

              250       260                                        
pF1KB5 RARVADRLYGVYKVHGNYGRVF--------------------------------SEWSAI
       ::::::::::::::::::::::                                ::::::
XP_016 RARVADRLYGVYKVHGNYGRVFRHSWSLFFFLISWSYKILERPLWFFSSSSRSKSEWSAI
              250       260       270       280       290       300

      270       280       290       300       310       320        
pF1KB5 EKEMGDGLQSAGHHMDVYASSIDDILEDEEHYADQLKEYLFYAEALRAVCRKHELMQYDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKEMGDGLQSAGHHMDVYASSIDDILEDEEHYADQLKEYLFYAEALRAVCRKHELMQYDL
              310       320       330       340       350       360

      330       340       350       360       370       380        
pF1KB5 EMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQ
              370       380       390       400       410       420

      390       400       410       420       430       440        
pF1KB5 LKSKNLEGREFVKNAWADIERFKEQKNRDLKEALISYAVMQISMCKKGIQVWTNAKECFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSKNLEGREFVKNAWADIERFKEQKNRDLKEALISYAVMQISMCKKGIQVWTNAKECFS
              430       440       450       460       470       480

      450
pF1KB5 KM
       ::
XP_016 KM
         

>>XP_016856917 (OMIM: 614904) PREDICTED: sorting nexin-7  (336 aa)
 initn: 241 init1: 113 opt: 333  Z-score: 345.6  bits: 72.7 E(85289): 1.6e-12
Smith-Waterman score: 342; 25.5% identity (60.2% similar) in 322 aa overlap (55-371:29-335)

           30        40        50        60        70        80    
pF1KB5 AGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYL
                                     :: . :.:.: :..     ..  ::. .: 
XP_016   MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESH-----VTTIETFITYR
                 10        20        30        40             50   

           90       100       110       120       130       140    
pF1KB5 IETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSAD
       : :.. .    .: .   . :::..:  :.. :   .: ...::::::   :. . . ..
XP_016 IITKTSRGEFDSSEFE--VRRRYQDFLWLKGKLEEAHPTLIIPPLPEK---FIVKGM-VE
            60          70        80        90          100        

          150       160       170       180       190          200 
pF1KB5 NMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET---GFQLKAD
        .. ::.: :: .:..:: :::.:: :  .. : .::: .. :. . ..    :.  .  
XP_016 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQA-WELSSHKKQGPGLLSRMG
       110       120       130       140        150       160      

             210        220       230       240       250       260
pF1KB5 SRLKALNATFR-VKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGR
       . ..:. ...: :::  ..: ..... . ... :. . ..  :.  .    .    .:: 
XP_016 QTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGP
        170       180       190       200       210       220      

              270       280       290        300       310         
pF1KB5 VFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALRAVCR
       .   ::: :... : :....  .:   .. .  .    :     ..::..:.: : .: .
XP_016 IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMK
        230       240       250       260       270       280      

     320       330       340       350       360       370         
pF1KB5 KHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLE
       ... .: .:.  .. :. :: . . :  .: ..:  .   :.:  .:. :..        
XP_016 RRDQIQAELDSKVEVLTYKKADTD-LCLATWESFLTS--QTNLHLEEASEDKP       
        290       300       310        320         330             

     380       390       400       410       420       430         
pF1KB5 EQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKEALISYAVMQISMCKKGIQV

>>XP_006710740 (OMIM: 614904) PREDICTED: sorting nexin-7  (422 aa)
 initn: 241 init1: 113 opt: 333  Z-score: 344.1  bits: 72.8 E(85289): 2e-12
Smith-Waterman score: 342; 25.5% identity (60.2% similar) in 322 aa overlap (55-371:115-421)

           30        40        50        60        70        80    
pF1KB5 AGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYL
                                     :: . :.:.: :..     ..  ::. .: 
XP_006 SLMDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESH-----VTTIETFITYR
           90       100       110       120            130         

           90       100       110       120       130       140    
pF1KB5 IETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSAD
       : :.. .    .: .   . :::..:  :.. :   .: ...::::::   :. . . ..
XP_006 IITKTSRGEFDSSEFE--VRRRYQDFLWLKGKLEEAHPTLIIPPLPEK---FIVKGM-VE
     140       150         160       170       180          190    

          150       160       170       180       190          200 
pF1KB5 NMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET---GFQLKAD
        .. ::.: :: .:..:: :::.:: :  .. : .::: .. :. . ..    :.  .  
XP_006 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQA-WELSSHKKQGPGLLSRMG
           200       210       220       230        240       250  

             210        220       230       240       250       260
pF1KB5 SRLKALNATFR-VKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGR
       . ..:. ...: :::  ..: ..... . ... :. . ..  :.  .    .    .:: 
XP_006 QTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGP
            260       270       280       290       300       310  

              270       280       290        300       310         
pF1KB5 VFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALRAVCR
       .   ::: :... : :....  .:   .. .  .    :     ..::..:.: : .: .
XP_006 IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMK
            320       330       340       350       360       370  

     320       330       340       350       360       370         
pF1KB5 KHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLE
       ... .: .:.  .. :. :: . . :  .: ..:  .   :.:  .:. :..        
XP_006 RRDQIQAELDSKVEVLTYKKADTD-LCLATWESFLTS--QTNLHLEEASEDKP       
            380       390        400         410       420         

     380       390       400       410       420       430         
pF1KB5 EQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKEALISYAVMQISMCKKGIQV

>>XP_006710741 (OMIM: 614904) PREDICTED: sorting nexin-7  (387 aa)
 initn: 279 init1: 113 opt: 330  Z-score: 341.6  bits: 72.2 E(85289): 2.7e-12
Smith-Waterman score: 339; 25.7% identity (60.5% similar) in 296 aa overlap (55-345:29-312)

           30        40        50        60        70        80    
pF1KB5 AGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYL
                                     :: . :.:.: :..     ..  ::. .: 
XP_006   MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESH-----VTTIETFITYR
                 10        20        30        40             50   

           90       100       110       120       130       140    
pF1KB5 IETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSAD
       : :.. .    .: .   . :::..:  :.. :   .: ...::::::   :. . . ..
XP_006 IITKTSRGEFDSSEF--EVRRRYQDFLWLKGKLEEAHPTLIIPPLPEK---FIVKGM-VE
            60          70        80        90          100        

          150       160       170       180       190          200 
pF1KB5 NMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET---GFQLKAD
        .. ::.: :: .:..:: :::.:: :  .. : .::: .. :. . ..    :.  .  
XP_006 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQA-WELSSHKKQGPGLLSRMG
       110       120       130       140        150       160      

             210        220       230       240       250       260
pF1KB5 SRLKALNATFR-VKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGR
       . ..:. ...: :::  ..: ..... . ... :. . ..  :.  .    .    .:: 
XP_006 QTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGP
        170       180       190       200       210       220      

              270       280       290        300       310         
pF1KB5 VFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALRAVCR
       .   ::: :... : :....  .:   .. .  .    :     ..::..:.: : .: .
XP_006 IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMK
        230       240       250       260       270       280      

     320       330       340       350       360       370         
pF1KB5 KHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLE
       ... .: .:.  .. :. :: . . :                                  
XP_006 RRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIK
        290       300       310       320       330       340      

>>XP_016856916 (OMIM: 614904) PREDICTED: sorting nexin-7  (387 aa)
 initn: 279 init1: 113 opt: 330  Z-score: 341.6  bits: 72.2 E(85289): 2.7e-12
Smith-Waterman score: 339; 25.7% identity (60.5% similar) in 296 aa overlap (55-345:29-312)

           30        40        50        60        70        80    
pF1KB5 AGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYL
                                     :: . :.:.: :..     ..  ::. .: 
XP_016   MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESH-----VTTIETFITYR
                 10        20        30        40             50   

           90       100       110       120       130       140    
pF1KB5 IETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSAD
       : :.. .    .: .   . :::..:  :.. :   .: ...::::::   :. . . ..
XP_016 IITKTSRGEFDSSEF--EVRRRYQDFLWLKGKLEEAHPTLIIPPLPEK---FIVKGM-VE
            60          70        80        90          100        

          150       160       170       180       190          200 
pF1KB5 NMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET---GFQLKAD
        .. ::.: :: .:..:: :::.:: :  .. : .::: .. :. . ..    :.  .  
XP_016 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQA-WELSSHKKQGPGLLSRMG
       110       120       130       140        150       160      

             210        220       230       240       250       260
pF1KB5 SRLKALNATFR-VKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGR
       . ..:. ...: :::  ..: ..... . ... :. . ..  :.  .    .    .:: 
XP_016 QTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGP
        170       180       190       200       210       220      

              270       280       290        300       310         
pF1KB5 VFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALRAVCR
       .   ::: :... : :....  .:   .. .  .    :     ..::..:.: : .: .
XP_016 IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMK
        230       240       250       260       270       280      

     320       330       340       350       360       370         
pF1KB5 KHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLE
       ... .: .:.  .. :. :: . . :                                  
XP_016 RRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIK
        290       300       310       320       330       340      

>>XP_016856915 (OMIM: 614904) PREDICTED: sorting nexin-7  (387 aa)
 initn: 279 init1: 113 opt: 330  Z-score: 341.6  bits: 72.2 E(85289): 2.7e-12
Smith-Waterman score: 339; 25.7% identity (60.5% similar) in 296 aa overlap (55-345:29-312)

           30        40        50        60        70        80    
pF1KB5 AGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYL
                                     :: . :.:.: :..     ..  ::. .: 
XP_016   MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESH-----VTTIETFITYR
                 10        20        30        40             50   

           90       100       110       120       130       140    
pF1KB5 IETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSAD
       : :.. .    .: .   . :::..:  :.. :   .: ...::::::   :. . . ..
XP_016 IITKTSRGEFDSSEF--EVRRRYQDFLWLKGKLEEAHPTLIIPPLPEK---FIVKGM-VE
            60          70        80        90          100        

          150       160       170       180       190          200 
pF1KB5 NMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET---GFQLKAD
        .. ::.: :: .:..:: :::.:: :  .. : .::: .. :. . ..    :.  .  
XP_016 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQA-WELSSHKKQGPGLLSRMG
       110       120       130       140        150       160      

             210        220       230       240       250       260
pF1KB5 SRLKALNATFR-VKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGR
       . ..:. ...: :::  ..: ..... . ... :. . ..  :.  .    .    .:: 
XP_016 QTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGP
        170       180       190       200       210       220      

              270       280       290        300       310         
pF1KB5 VFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALRAVCR
       .   ::: :... : :....  .:   .. .  .    :     ..::..:.: : .: .
XP_016 IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMK
        230       240       250       260       270       280      

     320       330       340       350       360       370         
pF1KB5 KHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLE
       ... .: .:.  .. :. :: . . :                                  
XP_016 RRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIK
        290       300       310       320       330       340      

>>XP_011539866 (OMIM: 614904) PREDICTED: sorting nexin-7  (387 aa)
 initn: 279 init1: 113 opt: 330  Z-score: 341.6  bits: 72.2 E(85289): 2.7e-12
Smith-Waterman score: 339; 25.7% identity (60.5% similar) in 296 aa overlap (55-345:29-312)

           30        40        50        60        70        80    
pF1KB5 AGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYL
                                     :: . :.:.: :..     ..  ::. .: 
XP_011   MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESH-----VTTIETFITYR
                 10        20        30        40             50   

           90       100       110       120       130       140    
pF1KB5 IETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSAD
       : :.. .    .: .   . :::..:  :.. :   .: ...::::::   :. . . ..
XP_011 IITKTSRGEFDSSEF--EVRRRYQDFLWLKGKLEEAHPTLIIPPLPEK---FIVKGM-VE
            60          70        80        90          100        

          150       160       170       180       190          200 
pF1KB5 NMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET---GFQLKAD
        .. ::.: :: .:..:: :::.:: :  .. : .::: .. :. . ..    :.  .  
XP_011 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQA-WELSSHKKQGPGLLSRMG
       110       120       130       140        150       160      

             210        220       230       240       250       260
pF1KB5 SRLKALNATFR-VKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGR
       . ..:. ...: :::  ..: ..... . ... :. . ..  :.  .    .    .:: 
XP_011 QTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGP
        170       180       190       200       210       220      

              270       280       290        300       310         
pF1KB5 VFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALRAVCR
       .   ::: :... : :....  .:   .. .  .    :     ..::..:.: : .: .
XP_011 IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMK
        230       240       250       260       270       280      

     320       330       340       350       360       370         
pF1KB5 KHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLE
       ... .: .:.  .. :. :: . . :                                  
XP_011 RRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIK
        290       300       310       320       330       340      

>>XP_016856914 (OMIM: 614904) PREDICTED: sorting nexin-7  (387 aa)
 initn: 279 init1: 113 opt: 330  Z-score: 341.6  bits: 72.2 E(85289): 2.7e-12
Smith-Waterman score: 339; 25.7% identity (60.5% similar) in 296 aa overlap (55-345:29-312)

           30        40        50        60        70        80    
pF1KB5 AGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYL
                                     :: . :.:.: :..     ..  ::. .: 
XP_016   MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESH-----VTTIETFITYR
                 10        20        30        40             50   

           90       100       110       120       130       140    
pF1KB5 IETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSAD
       : :.. .    .: .   . :::..:  :.. :   .: ...::::::   :. . . ..
XP_016 IITKTSRGEFDSSEF--EVRRRYQDFLWLKGKLEEAHPTLIIPPLPEK---FIVKGM-VE
            60          70        80        90          100        

          150       160       170       180       190          200 
pF1KB5 NMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET---GFQLKAD
        .. ::.: :: .:..:: :::.:: :  .. : .::: .. :. . ..    :.  .  
XP_016 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQA-WELSSHKKQGPGLLSRMG
       110       120       130       140        150       160      

             210        220       230       240       250       260
pF1KB5 SRLKALNATFR-VKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGR
       . ..:. ...: :::  ..: ..... . ... :. . ..  :.  .    .    .:: 
XP_016 QTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGP
        170       180       190       200       210       220      

              270       280       290        300       310         
pF1KB5 VFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALRAVCR
       .   ::: :... : :....  .:   .. .  .    :     ..::..:.: : .: .
XP_016 IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMK
        230       240       250       260       270       280      

     320       330       340       350       360       370         
pF1KB5 KHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLE
       ... .: .:.  .. :. :: . . :                                  
XP_016 RRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIK
        290       300       310       320       330       340      

>>NP_057060 (OMIM: 614904) sorting nexin-7 isoform a [Ho  (451 aa)
 initn: 241 init1: 113 opt: 330  Z-score: 340.7  bits: 72.2 E(85289): 3.1e-12
Smith-Waterman score: 339; 25.7% identity (60.5% similar) in 296 aa overlap (55-345:93-376)

           30        40        50        60        70        80    
pF1KB5 AGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYL
                                     :: . :.:.: :..     ..  ::. .: 
NP_057 SLMDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESH-----VTTIETFITYR
             70        80        90       100            110       

           90       100       110       120       130       140    
pF1KB5 IETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSAD
       : :.. .    .: .   . :::..:  :.. :   .: ...::::::   :. . . ..
NP_057 IITKTSRGEFDSSEF--EVRRRYQDFLWLKGKLEEAHPTLIIPPLPEK---FIVKGM-VE
       120       130         140       150       160           170 

          150       160       170       180       190          200 
pF1KB5 NMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET---GFQLKAD
        .. ::.: :: .:..:: :::.:: :  .. : .::: .. :. . ..    :.  .  
NP_057 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQA-WELSSHKKQGPGLLSRMG
             180       190       200       210        220       230

             210        220       230       240       250       260
pF1KB5 SRLKALNATFR-VKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGR
       . ..:. ...: :::  ..: ..... . ... :. . ..  :.  .    .    .:: 
NP_057 QTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGP
              240       250       260       270       280       290

              270       280       290        300       310         
pF1KB5 VFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALRAVCR
       .   ::: :... : :....  .:   .. .  .    :     ..::..:.: : .: .
NP_057 IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMK
              300       310       320       330       340       350

     320       330       340       350       360       370         
pF1KB5 KHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLE
       ... .: .:.  .. :. :: . . :                                  
NP_057 RRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIK
              360       370       380       390       400       410




450 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 12:28:23 2016 done: Sat Nov  5 12:28:24 2016
 Total Scan time:  9.100 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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