FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5334, 522 aa 1>>>pF1KB5334 522 - 522 aa - 522 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.9605+/-0.000416; mu= 3.3489+/- 0.026 mean_var=257.5553+/-54.059, 0's: 0 Z-trim(119.5): 21 B-trim: 667 in 1/57 Lambda= 0.079917 statistics sampled from 33599 (33620) to 33599 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.394), width: 16 Scan time: 11.300 The best scores are: opt bits E(85289) NP_036311 (OMIM: 260300,605648) F-box only protein ( 522) 3548 422.5 1.6e-117 NP_001028196 (OMIM: 260300,605648) F-box only prot ( 443) 2937 351.9 2.2e-96 NP_001244919 (OMIM: 260300,605648) F-box only prot ( 408) 2795 335.5 1.8e-91 XP_011528408 (OMIM: 260300,605648) PREDICTED: F-bo ( 366) 2508 302.4 1.5e-81 >>NP_036311 (OMIM: 260300,605648) F-box only protein 7 i (522 aa) initn: 3548 init1: 3548 opt: 3548 Z-score: 2231.0 bits: 422.5 E(85289): 1.6e-117 Smith-Waterman score: 3548; 99.8% identity (100.0% similar) in 522 aa overlap (1-522:1-522) 10 20 30 40 50 60 pF1KB5 MRLRVRLLKRTWPLEVPETEPTLGHLRSHLRQSLLCTWGYSSNTRFTITLNYKDPLTGDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MRLRVRLLKRTWPLEVPETEPTLGHLRSHLRQSLLCTWGYSSNTRFTITLNYKDPLTGDE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ETLASYGIVSGDLICLILQDDIPAPNIPSSTDSEHSSLQNNEQPSLATSSNQTSIQDEQP ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: NP_036 ETLASYGIVSGDLICLILQDDIPAPNIPSSTDSEHSSLQNNEQPSLATSSNQTSMQDEQP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SDSFQGQAAQSGVWNDDSMLGPSQNFEAESIQDNAHMAEGTGFYPSEPMLCSESVEGQVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SDSFQGQAAQSGVWNDDSMLGPSQNFEAESIQDNAHMAEGTGFYPSEPMLCSESVEGQVP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 HSLETLYQSADCSDANDALIVLIHLLMLESGYIPQGTEAKALSMPEKWKLSGVYKLQYMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 HSLETLYQSADCSDANDALIVLIHLLMLESGYIPQGTEAKALSMPEKWKLSGVYKLQYMH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 PLCEGSSATLTCVPLGNLIVVNATLKINNEIRSVKRLQLLPESFICKEKLGENVANIYKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 PLCEGSSATLTCVPLGNLIVVNATLKINNEIRSVKRLQLLPESFICKEKLGENVANIYKD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 LQKLSRLFKDQLVYPLLAFTRQALNLPDVFGLVVLPLELKLRIFRLLDVRSVLSLSAVCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LQKLSRLFKDQLVYPLLAFTRQALNLPDVFGLVVLPLELKLRIFRLLDVRSVLSLSAVCR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 DLFTASNDPLLWRFLYLRDFRDNTVRVQDTDWKELYRKRHIQRKESPKGRFVMLLPSSTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 DLFTASNDPLLWRFLYLRDFRDNTVRVQDTDWKELYRKRHIQRKESPKGRFVMLLPSSTH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 TIPFYPNPLHPRPFPSSRLPPGIIGGEYDQRPTLPYVGDPISSLIPGPGETPSQFPPLRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 TIPFYPNPLHPRPFPSSRLPPGIIGGEYDQRPTLPYVGDPISSLIPGPGETPSQFPPLRP 430 440 450 460 470 480 490 500 510 520 pF1KB5 RFDPVGPLPGPNPILPGRGGPNDRFPFRPSRGRPTDGRLSFM :::::::::::::::::::::::::::::::::::::::::: NP_036 RFDPVGPLPGPNPILPGRGGPNDRFPFRPSRGRPTDGRLSFM 490 500 510 520 >>NP_001028196 (OMIM: 260300,605648) F-box only protein (443 aa) initn: 2937 init1: 2937 opt: 2937 Z-score: 1851.2 bits: 351.9 E(85289): 2.2e-96 Smith-Waterman score: 2937; 99.8% identity (100.0% similar) in 431 aa overlap (92-522:13-443) 70 80 90 100 110 120 pF1KB5 TLASYGIVSGDLICLILQDDIPAPNIPSSTDSEHSSLQNNEQPSLATSSNQTSIQDEQPS :::::::::::::::::::::::.:::::: NP_001 MARPPGGSGPLLDSEHSSLQNNEQPSLATSSNQTSMQDEQPS 10 20 30 40 130 140 150 160 170 180 pF1KB5 DSFQGQAAQSGVWNDDSMLGPSQNFEAESIQDNAHMAEGTGFYPSEPMLCSESVEGQVPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSFQGQAAQSGVWNDDSMLGPSQNFEAESIQDNAHMAEGTGFYPSEPMLCSESVEGQVPH 50 60 70 80 90 100 190 200 210 220 230 240 pF1KB5 SLETLYQSADCSDANDALIVLIHLLMLESGYIPQGTEAKALSMPEKWKLSGVYKLQYMHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLETLYQSADCSDANDALIVLIHLLMLESGYIPQGTEAKALSMPEKWKLSGVYKLQYMHP 110 120 130 140 150 160 250 260 270 280 290 300 pF1KB5 LCEGSSATLTCVPLGNLIVVNATLKINNEIRSVKRLQLLPESFICKEKLGENVANIYKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LCEGSSATLTCVPLGNLIVVNATLKINNEIRSVKRLQLLPESFICKEKLGENVANIYKDL 170 180 190 200 210 220 310 320 330 340 350 360 pF1KB5 QKLSRLFKDQLVYPLLAFTRQALNLPDVFGLVVLPLELKLRIFRLLDVRSVLSLSAVCRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKLSRLFKDQLVYPLLAFTRQALNLPDVFGLVVLPLELKLRIFRLLDVRSVLSLSAVCRD 230 240 250 260 270 280 370 380 390 400 410 420 pF1KB5 LFTASNDPLLWRFLYLRDFRDNTVRVQDTDWKELYRKRHIQRKESPKGRFVMLLPSSTHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFTASNDPLLWRFLYLRDFRDNTVRVQDTDWKELYRKRHIQRKESPKGRFVMLLPSSTHT 290 300 310 320 330 340 430 440 450 460 470 480 pF1KB5 IPFYPNPLHPRPFPSSRLPPGIIGGEYDQRPTLPYVGDPISSLIPGPGETPSQFPPLRPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPFYPNPLHPRPFPSSRLPPGIIGGEYDQRPTLPYVGDPISSLIPGPGETPSQFPPLRPR 350 360 370 380 390 400 490 500 510 520 pF1KB5 FDPVGPLPGPNPILPGRGGPNDRFPFRPSRGRPTDGRLSFM ::::::::::::::::::::::::::::::::::::::::: NP_001 FDPVGPLPGPNPILPGRGGPNDRFPFRPSRGRPTDGRLSFM 410 420 430 440 >>NP_001244919 (OMIM: 260300,605648) F-box only protein (408 aa) initn: 2795 init1: 2795 opt: 2795 Z-score: 1763.2 bits: 335.5 E(85289): 1.8e-91 Smith-Waterman score: 2795; 99.8% identity (100.0% similar) in 408 aa overlap (115-522:1-408) 90 100 110 120 130 140 pF1KB5 PNIPSSTDSEHSSLQNNEQPSLATSSNQTSIQDEQPSDSFQGQAAQSGVWNDDSMLGPSQ .::::::::::::::::::::::::::::: NP_001 MQDEQPSDSFQGQAAQSGVWNDDSMLGPSQ 10 20 30 150 160 170 180 190 200 pF1KB5 NFEAESIQDNAHMAEGTGFYPSEPMLCSESVEGQVPHSLETLYQSADCSDANDALIVLIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NFEAESIQDNAHMAEGTGFYPSEPMLCSESVEGQVPHSLETLYQSADCSDANDALIVLIH 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB5 LLMLESGYIPQGTEAKALSMPEKWKLSGVYKLQYMHPLCEGSSATLTCVPLGNLIVVNAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLMLESGYIPQGTEAKALSMPEKWKLSGVYKLQYMHPLCEGSSATLTCVPLGNLIVVNAT 100 110 120 130 140 150 270 280 290 300 310 320 pF1KB5 LKINNEIRSVKRLQLLPESFICKEKLGENVANIYKDLQKLSRLFKDQLVYPLLAFTRQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKINNEIRSVKRLQLLPESFICKEKLGENVANIYKDLQKLSRLFKDQLVYPLLAFTRQAL 160 170 180 190 200 210 330 340 350 360 370 380 pF1KB5 NLPDVFGLVVLPLELKLRIFRLLDVRSVLSLSAVCRDLFTASNDPLLWRFLYLRDFRDNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLPDVFGLVVLPLELKLRIFRLLDVRSVLSLSAVCRDLFTASNDPLLWRFLYLRDFRDNT 220 230 240 250 260 270 390 400 410 420 430 440 pF1KB5 VRVQDTDWKELYRKRHIQRKESPKGRFVMLLPSSTHTIPFYPNPLHPRPFPSSRLPPGII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRVQDTDWKELYRKRHIQRKESPKGRFVMLLPSSTHTIPFYPNPLHPRPFPSSRLPPGII 280 290 300 310 320 330 450 460 470 480 490 500 pF1KB5 GGEYDQRPTLPYVGDPISSLIPGPGETPSQFPPLRPRFDPVGPLPGPNPILPGRGGPNDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGEYDQRPTLPYVGDPISSLIPGPGETPSQFPPLRPRFDPVGPLPGPNPILPGRGGPNDR 340 350 360 370 380 390 510 520 pF1KB5 FPFRPSRGRPTDGRLSFM :::::::::::::::::: NP_001 FPFRPSRGRPTDGRLSFM 400 >>XP_011528408 (OMIM: 260300,605648) PREDICTED: F-box on (366 aa) initn: 2508 init1: 2508 opt: 2508 Z-score: 1585.0 bits: 302.4 E(85289): 1.5e-81 Smith-Waterman score: 2508; 100.0% identity (100.0% similar) in 366 aa overlap (157-522:1-366) 130 140 150 160 170 180 pF1KB5 QAAQSGVWNDDSMLGPSQNFEAESIQDNAHMAEGTGFYPSEPMLCSESVEGQVPHSLETL :::::::::::::::::::::::::::::: XP_011 MAEGTGFYPSEPMLCSESVEGQVPHSLETL 10 20 30 190 200 210 220 230 240 pF1KB5 YQSADCSDANDALIVLIHLLMLESGYIPQGTEAKALSMPEKWKLSGVYKLQYMHPLCEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQSADCSDANDALIVLIHLLMLESGYIPQGTEAKALSMPEKWKLSGVYKLQYMHPLCEGS 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB5 SATLTCVPLGNLIVVNATLKINNEIRSVKRLQLLPESFICKEKLGENVANIYKDLQKLSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SATLTCVPLGNLIVVNATLKINNEIRSVKRLQLLPESFICKEKLGENVANIYKDLQKLSR 100 110 120 130 140 150 310 320 330 340 350 360 pF1KB5 LFKDQLVYPLLAFTRQALNLPDVFGLVVLPLELKLRIFRLLDVRSVLSLSAVCRDLFTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LFKDQLVYPLLAFTRQALNLPDVFGLVVLPLELKLRIFRLLDVRSVLSLSAVCRDLFTAS 160 170 180 190 200 210 370 380 390 400 410 420 pF1KB5 NDPLLWRFLYLRDFRDNTVRVQDTDWKELYRKRHIQRKESPKGRFVMLLPSSTHTIPFYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NDPLLWRFLYLRDFRDNTVRVQDTDWKELYRKRHIQRKESPKGRFVMLLPSSTHTIPFYP 220 230 240 250 260 270 430 440 450 460 470 480 pF1KB5 NPLHPRPFPSSRLPPGIIGGEYDQRPTLPYVGDPISSLIPGPGETPSQFPPLRPRFDPVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPLHPRPFPSSRLPPGIIGGEYDQRPTLPYVGDPISSLIPGPGETPSQFPPLRPRFDPVG 280 290 300 310 320 330 490 500 510 520 pF1KB5 PLPGPNPILPGRGGPNDRFPFRPSRGRPTDGRLSFM :::::::::::::::::::::::::::::::::::: XP_011 PLPGPNPILPGRGGPNDRFPFRPSRGRPTDGRLSFM 340 350 360 522 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 17:11:36 2016 done: Thu Nov 3 17:11:38 2016 Total Scan time: 11.300 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]