Result of FASTA (omim) for
pF1KB5339
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5339, 534 aa
1>>>pF1KB5339 534 - 534 aa - 534 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.8048+/-0.000299; mu= 8.0616+/- 0.019
mean_var=141.0054+/-28.112, 0's: 0 Z-trim(121.2): 20 B-trim: 0 in 0/58
Lambda= 0.108008
statistics sampled from 37446 (37468) to 37446 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.439), width: 16
Scan time: 11.780
The best scores are: opt bits E(85289)
NP_003787 (OMIM: 603494) unconventional prefoldin ( 535) 3512 558.5 1.8e-158
XP_005259419 (OMIM: 603494) PREDICTED: unconventio ( 517) 3250 517.7 3.5e-146
XP_011525737 (OMIM: 603494) PREDICTED: unconventio ( 487) 3183 507.2 4.6e-143
XP_005259420 (OMIM: 603494) PREDICTED: unconventio ( 493) 3132 499.3 1.1e-140
NP_001239570 (OMIM: 603494) unconventional prefold ( 475) 2870 458.4 2.2e-128
>>NP_003787 (OMIM: 603494) unconventional prefoldin RPB5 (535 aa)
initn: 2103 init1: 2103 opt: 3512 Z-score: 2965.9 bits: 558.5 E(85289): 1.8e-158
Smith-Waterman score: 3512; 99.6% identity (99.8% similar) in 535 aa overlap (1-534:1-535)
10 20 30 40 50 60
pF1KB5 MEAPTVETPPDPSPPSAPAPVLVPLRAPDVARLREEQEKVVTNCQERIQHWKKVDNDYNA
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
NP_003 MEAPTVETPPDPSPPSAPAPALVPLRAPDVARLREEQEKVVTNCQERIQHWKKVDNDYNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LRERLSTLPDKLSYNIMVPFGPFAFMPGKLVHTNEVTVLLGDNWFAKCSAKQAVGLVEHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LRERLSTLPDKLSYNIMVPFGPFAFMPGKLVHTNEVTVLLGDNWFAKCSAKQAVGLVEHR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KEHVRKTIDDLKKVMKNFESRVEFTEDLQKMSDAAGDIVDIREEIKCDFEFKAKHRIAHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KEHVRKTIDDLKKVMKNFESRVEFTEDLQKMSDAAGDIVDIREEIKCDFEFKAKHRIAHK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 PHSKPKTSDIFEADIANDVKSKDLLADKELWARLEELERQEELLGELDSKPDTVIANGED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PHSKPKTSDIFEADIANDVKSKDLLADKELWARLEELERQEELLGELDSKPDTVIANGED
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 TTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDD
250 260 270 280 290 300
310 320 330 340 350
pF1KB5 DDDDDDDDDD-NIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTGKNTTLKFSE
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTGKNTTLKFSE
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 KKEEAKRKRKNSTGSGHSAQELPTIRTPADIYRAFVDVVNGEYVPRKSILKSRSRENSVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KKEEAKRKRKNSTGSGHSAQELPTIRTPADIYRAFVDVVNGEYVPRKSILKSRSRENSVC
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB5 SDTSESSAAEFDDRRGVLRSISCEEATCSDTSESILEEEPQENQKKLLPLSVTPEAFSGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SDTSESSAAEFDDRRGVLRSISCEEATCSDTSESILEEEPQENQKKLLPLSVTPEAFSGT
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB5 VIEKEFVSPSLTPPPAIAHPALPTIPERKEVLLEASEETGKRVSKFKAARLQQKD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VIEKEFVSPSLTPPPAIAHPALPTIPERKEVLLEASEETGKRVSKFKAARLQQKD
490 500 510 520 530
>>XP_005259419 (OMIM: 603494) PREDICTED: unconventional (517 aa)
initn: 1841 init1: 1841 opt: 3250 Z-score: 2745.5 bits: 517.7 E(85289): 3.5e-146
Smith-Waterman score: 3250; 99.8% identity (99.8% similar) in 496 aa overlap (40-534:22-517)
10 20 30 40 50 60
pF1KB5 PDPSPPSAPAPVLVPLRAPDVARLREEQEKVVTNCQERIQHWKKVDNDYNALRERLSTLP
::::::::::::::::::::::::::::::
XP_005 MTTWSSLQGSHVSKRALAYALVVTNCQERIQHWKKVDNDYNALRERLSTLP
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 DKLSYNIMVPFGPFAFMPGKLVHTNEVTVLLGDNWFAKCSAKQAVGLVEHRKEHVRKTID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DKLSYNIMVPFGPFAFMPGKLVHTNEVTVLLGDNWFAKCSAKQAVGLVEHRKEHVRKTID
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 DLKKVMKNFESRVEFTEDLQKMSDAAGDIVDIREEIKCDFEFKAKHRIAHKPHSKPKTSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLKKVMKNFESRVEFTEDLQKMSDAAGDIVDIREEIKCDFEFKAKHRIAHKPHSKPKTSD
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 IFEADIANDVKSKDLLADKELWARLEELERQEELLGELDSKPDTVIANGEDTTSSEEEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IFEADIANDVKSKDLLADKELWARLEELERQEELLGELDSKPDTVIANGEDTTSSEEEKE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB5 DRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDD
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB5 D-NIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKR
: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKR
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB5 KNSTGSGHSAQELPTIRTPADIYRAFVDVVNGEYVPRKSILKSRSRENSVCSDTSESSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KNSTGSGHSAQELPTIRTPADIYRAFVDVVNGEYVPRKSILKSRSRENSVCSDTSESSAA
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB5 EFDDRRGVLRSISCEEATCSDTSESILEEEPQENQKKLLPLSVTPEAFSGTVIEKEFVSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFDDRRGVLRSISCEEATCSDTSESILEEEPQENQKKLLPLSVTPEAFSGTVIEKEFVSP
420 430 440 450 460 470
490 500 510 520 530
pF1KB5 SLTPPPAIAHPALPTIPERKEVLLEASEETGKRVSKFKAARLQQKD
::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLTPPPAIAHPALPTIPERKEVLLEASEETGKRVSKFKAARLQQKD
480 490 500 510
>>XP_011525737 (OMIM: 603494) PREDICTED: unconventional (487 aa)
initn: 1774 init1: 1774 opt: 3183 Z-score: 2689.5 bits: 507.2 E(85289): 4.6e-143
Smith-Waterman score: 3183; 99.8% identity (99.8% similar) in 486 aa overlap (50-534:2-487)
20 30 40 50 60 70
pF1KB5 PVLVPLRAPDVARLREEQEKVVTNCQERIQHWKKVDNDYNALRERLSTLPDKLSYNIMVP
::::::::::::::::::::::::::::::
XP_011 MHWKKVDNDYNALRERLSTLPDKLSYNIMVP
10 20 30
80 90 100 110 120 130
pF1KB5 FGPFAFMPGKLVHTNEVTVLLGDNWFAKCSAKQAVGLVEHRKEHVRKTIDDLKKVMKNFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGPFAFMPGKLVHTNEVTVLLGDNWFAKCSAKQAVGLVEHRKEHVRKTIDDLKKVMKNFE
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB5 SRVEFTEDLQKMSDAAGDIVDIREEIKCDFEFKAKHRIAHKPHSKPKTSDIFEADIANDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRVEFTEDLQKMSDAAGDIVDIREEIKCDFEFKAKHRIAHKPHSKPKTSDIFEADIANDV
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB5 KSKDLLADKELWARLEELERQEELLGELDSKPDTVIANGEDTTSSEEEKEDRNTNVNAMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSKDLLADKELWARLEELERQEELLGELDSKPDTVIANGEDTTSSEEEKEDRNTNVNAMH
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB5 QVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDDD-NIDDDDGD
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_011 QVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGD
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB5 NDHEALGVGDNSIPTIYFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKRKNSTGSGHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDHEALGVGDNSIPTIYFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKRKNSTGSGHSA
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB5 QELPTIRTPADIYRAFVDVVNGEYVPRKSILKSRSRENSVCSDTSESSAAEFDDRRGVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QELPTIRTPADIYRAFVDVVNGEYVPRKSILKSRSRENSVCSDTSESSAAEFDDRRGVLR
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB5 SISCEEATCSDTSESILEEEPQENQKKLLPLSVTPEAFSGTVIEKEFVSPSLTPPPAIAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SISCEEATCSDTSESILEEEPQENQKKLLPLSVTPEAFSGTVIEKEFVSPSLTPPPAIAH
400 410 420 430 440 450
500 510 520 530
pF1KB5 PALPTIPERKEVLLEASEETGKRVSKFKAARLQQKD
::::::::::::::::::::::::::::::::::::
XP_011 PALPTIPERKEVLLEASEETGKRVSKFKAARLQQKD
460 470 480
>>XP_005259420 (OMIM: 603494) PREDICTED: unconventional (493 aa)
initn: 3256 init1: 2103 opt: 3132 Z-score: 2646.4 bits: 499.3 E(85289): 1.1e-140
Smith-Waterman score: 3132; 99.2% identity (99.8% similar) in 477 aa overlap (1-476:1-477)
10 20 30 40 50 60
pF1KB5 MEAPTVETPPDPSPPSAPAPVLVPLRAPDVARLREEQEKVVTNCQERIQHWKKVDNDYNA
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_005 MEAPTVETPPDPSPPSAPAPALVPLRAPDVARLREEQEKVVTNCQERIQHWKKVDNDYNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LRERLSTLPDKLSYNIMVPFGPFAFMPGKLVHTNEVTVLLGDNWFAKCSAKQAVGLVEHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRERLSTLPDKLSYNIMVPFGPFAFMPGKLVHTNEVTVLLGDNWFAKCSAKQAVGLVEHR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KEHVRKTIDDLKKVMKNFESRVEFTEDLQKMSDAAGDIVDIREEIKCDFEFKAKHRIAHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEHVRKTIDDLKKVMKNFESRVEFTEDLQKMSDAAGDIVDIREEIKCDFEFKAKHRIAHK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 PHSKPKTSDIFEADIANDVKSKDLLADKELWARLEELERQEELLGELDSKPDTVIANGED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PHSKPKTSDIFEADIANDVKSKDLLADKELWARLEELERQEELLGELDSKPDTVIANGED
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 TTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDD
250 260 270 280 290 300
310 320 330 340 350
pF1KB5 DDDDDDDDDD-NIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTGKNTTLKFSE
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTGKNTTLKFSE
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 KKEEAKRKRKNSTGSGHSAQELPTIRTPADIYRAFVDVVNGEYVPRKSILKSRSRENSVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKEEAKRKRKNSTGSGHSAQELPTIRTPADIYRAFVDVVNGEYVPRKSILKSRSRENSVC
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB5 SDTSESSAAEFDDRRGVLRSISCEEATCSDTSESILEEEPQENQKKLLPLSVTPEAFSGT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::..
XP_005 SDTSESSAAEFDDRRGVLRSISCEEATCSDTSESILEEEPQENQKKLLPLSVTPEVLRLV
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB5 VIEKEFVSPSLTPPPAIAHPALPTIPERKEVLLEASEETGKRVSKFKAARLQQKD
XP_005 GYSRNLAPLNVIL
490
>>NP_001239570 (OMIM: 603494) unconventional prefoldin R (475 aa)
initn: 2994 init1: 1841 opt: 2870 Z-score: 2426.0 bits: 458.4 E(85289): 2.2e-128
Smith-Waterman score: 2870; 99.3% identity (99.8% similar) in 438 aa overlap (40-476:22-459)
10 20 30 40 50 60
pF1KB5 PDPSPPSAPAPVLVPLRAPDVARLREEQEKVVTNCQERIQHWKKVDNDYNALRERLSTLP
::::::::::::::::::::::::::::::
NP_001 MTTWSSLQGSHVSKRALAYALVVTNCQERIQHWKKVDNDYNALRERLSTLP
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 DKLSYNIMVPFGPFAFMPGKLVHTNEVTVLLGDNWFAKCSAKQAVGLVEHRKEHVRKTID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKLSYNIMVPFGPFAFMPGKLVHTNEVTVLLGDNWFAKCSAKQAVGLVEHRKEHVRKTID
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 DLKKVMKNFESRVEFTEDLQKMSDAAGDIVDIREEIKCDFEFKAKHRIAHKPHSKPKTSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLKKVMKNFESRVEFTEDLQKMSDAAGDIVDIREEIKCDFEFKAKHRIAHKPHSKPKTSD
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 IFEADIANDVKSKDLLADKELWARLEELERQEELLGELDSKPDTVIANGEDTTSSEEEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFEADIANDVKSKDLLADKELWARLEELERQEELLGELDSKPDTVIANGEDTTSSEEEKE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB5 DRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDD
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB5 D-NIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKR
: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKR
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB5 KNSTGSGHSAQELPTIRTPADIYRAFVDVVNGEYVPRKSILKSRSRENSVCSDTSESSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNSTGSGHSAQELPTIRTPADIYRAFVDVVNGEYVPRKSILKSRSRENSVCSDTSESSAA
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB5 EFDDRRGVLRSISCEEATCSDTSESILEEEPQENQKKLLPLSVTPEAFSGTVIEKEFVSP
::::::::::::::::::::::::::::::::::::::::::::::..
NP_001 EFDDRRGVLRSISCEEATCSDTSESILEEEPQENQKKLLPLSVTPEVLRLVGYSRNLAPL
420 430 440 450 460 470
490 500 510 520 530
pF1KB5 SLTPPPAIAHPALPTIPERKEVLLEASEETGKRVSKFKAARLQQKD
NP_001 NVIL
534 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 17:13:02 2016 done: Thu Nov 3 17:13:04 2016
Total Scan time: 11.780 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]