FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5341, 346 aa 1>>>pF1KB5341 346 - 346 aa - 346 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5653+/-0.000382; mu= 14.1417+/- 0.024 mean_var=61.5709+/-12.443, 0's: 0 Z-trim(112.9): 72 B-trim: 1081 in 1/51 Lambda= 0.163451 statistics sampled from 22000 (22072) to 22000 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.259), width: 16 Scan time: 8.270 The best scores are: opt bits E(85289) NP_005491 (OMIM: 613294) SUMO-activating enzyme su ( 346) 2280 546.3 3.6e-155 XP_006723026 (OMIM: 613294) PREDICTED: SUMO-activa ( 378) 2062 494.9 1.2e-139 XP_016881625 (OMIM: 613294) PREDICTED: SUMO-activa ( 282) 1884 452.9 3.9e-127 XP_016881624 (OMIM: 613294) PREDICTED: SUMO-activa ( 349) 1590 383.6 3.5e-106 NP_001139186 (OMIM: 613294) SUMO-activating enzyme ( 266) 1585 382.4 6.2e-106 XP_006723028 (OMIM: 613294) PREDICTED: SUMO-activa ( 281) 1585 382.4 6.5e-106 NP_001139185 (OMIM: 613294) SUMO-activating enzyme ( 299) 1585 382.4 6.9e-106 NP_003325 (OMIM: 301830,314370) ubiquitin-like mod (1058) 363 94.4 1.2e-18 XP_016885269 (OMIM: 301830,314370) PREDICTED: ubiq (1058) 363 94.4 1.2e-18 NP_695012 (OMIM: 301830,314370) ubiquitin-like mod (1058) 363 94.4 1.2e-18 XP_016885270 (OMIM: 301830,314370) PREDICTED: ubiq (1058) 363 94.4 1.2e-18 XP_016885268 (OMIM: 301830,314370) PREDICTED: ubiq (1064) 363 94.4 1.2e-18 XP_005272706 (OMIM: 301830,314370) PREDICTED: ubiq (1064) 363 94.4 1.2e-18 XP_011542256 (OMIM: 301830,314370) PREDICTED: ubiq (1072) 363 94.4 1.2e-18 XP_016885267 (OMIM: 301830,314370) PREDICTED: ubiq (1086) 363 94.4 1.2e-18 XP_011532373 (OMIM: 191325) PREDICTED: ubiquitin-l ( 910) 362 94.1 1.2e-18 XP_016885266 (OMIM: 301830,314370) PREDICTED: ubiq (1109) 363 94.4 1.3e-18 XP_011532372 (OMIM: 191325) PREDICTED: ubiquitin-l ( 960) 362 94.1 1.3e-18 XP_005265487 (OMIM: 191325) PREDICTED: ubiquitin-l ( 987) 362 94.1 1.3e-18 XP_006713384 (OMIM: 191325) PREDICTED: ubiquitin-l (1005) 362 94.1 1.4e-18 NP_003326 (OMIM: 191325) ubiquitin-like modifier-a (1012) 362 94.1 1.4e-18 NP_003896 (OMIM: 603385) NEDD8-activating enzyme E ( 534) 334 87.5 7.4e-17 NP_001273429 (OMIM: 603385) NEDD8-activating enzym ( 537) 319 83.9 8.6e-16 NP_001018169 (OMIM: 603385) NEDD8-activating enzym ( 528) 301 79.7 1.6e-14 XP_016863848 (OMIM: 611361) PREDICTED: ubiquitin-l (1009) 303 80.2 2.1e-14 NP_060697 (OMIM: 611361) ubiquitin-like modifier-a (1052) 303 80.2 2.2e-14 XP_011532374 (OMIM: 191325) PREDICTED: ubiquitin-l ( 796) 197 55.2 5.6e-07 NP_005490 (OMIM: 613295) SUMO-activating enzyme su ( 640) 189 53.3 1.7e-06 NP_937838 (OMIM: 603172) NEDD8-activating enzyme E ( 449) 182 51.6 3.9e-06 NP_003959 (OMIM: 603172) NEDD8-activating enzyme E ( 463) 182 51.6 4e-06 XP_005256272 (OMIM: 603385) PREDICTED: NEDD8-activ ( 445) 149 43.8 0.00085 NP_001018170 (OMIM: 603385) NEDD8-activating enzym ( 445) 149 43.8 0.00085 XP_011521724 (OMIM: 603385) PREDICTED: NEDD8-activ ( 445) 149 43.8 0.00085 NP_055299 (OMIM: 609277) adenylyltransferase and s ( 460) 149 43.8 0.00088 >>NP_005491 (OMIM: 613294) SUMO-activating enzyme subuni (346 aa) initn: 2280 init1: 2280 opt: 2280 Z-score: 2906.7 bits: 546.3 E(85289): 3.6e-155 Smith-Waterman score: 2280; 100.0% identity (100.0% similar) in 346 aa overlap (1-346:1-346) 10 20 30 40 50 60 pF1KB5 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA 250 260 270 280 290 300 310 320 330 340 pF1KB5 PVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK :::::::::::::::::::::::::::::::::::::::::::::: NP_005 PVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK 310 320 330 340 >>XP_006723026 (OMIM: 613294) PREDICTED: SUMO-activating (378 aa) initn: 2094 init1: 2062 opt: 2062 Z-score: 2628.3 bits: 494.9 E(85289): 1.2e-139 Smith-Waterman score: 2062; 99.7% identity (100.0% similar) in 318 aa overlap (1-318:37-354) 10 20 30 pF1KB5 MVEKEEAGGGISEEEAAQYDRQIRLWGLEA :::::::::::::::::::::::::::::: XP_006 GVLPAAVGGARVRRAVGLSGTGAEAGRAGAMVEKEEAGGGISEEEAAQYDRQIRLWGLEA 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 QKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRN 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 RAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNS 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB5 IKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKK 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB5 VVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRTDKGRDPSSDTYEEDSELLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRTDKGRDPSSDTYEEDSELLL 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB5 QIRNDVLDSLGISPDLLPEDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFF ::::::::::::::::::::::::::::::::::::::::::::::.: XP_006 QIRNDVLDSLGISPDLLPEDFVRYCFSEMAPVCAVVGGILAQEIVKVLGCLRGLRPCLSG 310 320 330 340 350 360 340 pF1KB5 FDGMKGNGIVECLGPK XP_006 TLLTTTSSSSMA 370 >>XP_016881625 (OMIM: 613294) PREDICTED: SUMO-activating (282 aa) initn: 1884 init1: 1884 opt: 1884 Z-score: 2403.5 bits: 452.9 E(85289): 3.9e-127 Smith-Waterman score: 1884; 100.0% identity (100.0% similar) in 282 aa overlap (65-346:1-282) 40 50 60 70 80 90 pF1KB5 RASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEA :::::::::::::::::::::::::::::: XP_016 MLDHEQVTPEDPGAQFLIRTGSVGRNRAEA 10 20 30 100 110 120 130 140 150 pF1KB5 SLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFF 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB5 TGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFC 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB5 PVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRN 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB5 DVLDSLGISPDLLPEDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVLDSLGISPDLLPEDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGM 220 230 240 250 260 270 340 pF1KB5 KGNGIVECLGPK :::::::::::: XP_016 KGNGIVECLGPK 280 >>XP_016881624 (OMIM: 613294) PREDICTED: SUMO-activating (349 aa) initn: 1620 init1: 1588 opt: 1590 Z-score: 2027.3 bits: 383.6 E(85289): 3.5e-106 Smith-Waterman score: 1590; 91.9% identity (94.5% similar) in 273 aa overlap (1-270:37-308) 10 20 30 pF1KB5 MVEKEEAGGGISEEEAAQYDRQIRLWGLEA :::::::::::::::::::::::::::::: XP_016 GVLPAAVGGARVRRAVGLSGTGAEAGRAGAMVEKEEAGGGISEEEAAQYDRQIRLWGLEA 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 QKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRN 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 RAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNS 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB5 IKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKK 190 200 210 220 230 240 220 230 240 250 260 pF1KB5 VVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKF---RTDKGRDPSSDTYEEDSE :::::::::::::::::::::::::::::::::: :. :. : : : : . .. XP_016 VVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQELFPRIVERVYAQRHPRS-TERTHAK 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB5 LLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNN .:. XP_016 MLIPFLTKEKPGFLGEMAVSRSGVGKLQFAFSITWASPEPKPRH 310 320 330 340 >>NP_001139186 (OMIM: 613294) SUMO-activating enzyme sub (266 aa) initn: 1585 init1: 1585 opt: 1585 Z-score: 2022.9 bits: 382.4 E(85289): 6.2e-106 Smith-Waterman score: 1585; 100.0% identity (100.0% similar) in 244 aa overlap (1-244:1-244) 10 20 30 40 50 60 pF1KB5 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA :::: NP_001 FLLQGTASPRWPQCVRWLEGFWHRKL 250 260 >>XP_006723028 (OMIM: 613294) PREDICTED: SUMO-activating (281 aa) initn: 1585 init1: 1585 opt: 1585 Z-score: 2022.5 bits: 382.4 E(85289): 6.5e-106 Smith-Waterman score: 1585; 100.0% identity (100.0% similar) in 244 aa overlap (1-244:37-280) 10 20 30 pF1KB5 MVEKEEAGGGISEEEAAQYDRQIRLWGLEA :::::::::::::::::::::::::::::: XP_006 GVLPAAVGGARVRRAVGLSGTGAEAGRAGAMVEKEEAGGGISEEEAAQYDRQIRLWGLEA 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 QKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRN 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 RAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNS 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB5 IKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKK 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB5 VVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRTDKGRDPSSDTYEEDSELLL :::::::::::::::::::::::::::::::::: XP_006 VVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQA 250 260 270 280 280 290 300 310 320 330 pF1KB5 QIRNDVLDSLGISPDLLPEDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFF >>NP_001139185 (OMIM: 613294) SUMO-activating enzyme sub (299 aa) initn: 1585 init1: 1585 opt: 1585 Z-score: 2022.0 bits: 382.4 E(85289): 6.9e-106 Smith-Waterman score: 1585; 100.0% identity (100.0% similar) in 244 aa overlap (1-244:1-244) 10 20 30 40 50 60 pF1KB5 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA :::: NP_001 FLLQGPVSAGPSSQQLLLLRWHEGEWDCGVPWPQVNSRFGSPRDANCSMPTCIPCPLPS 250 260 270 280 290 >>NP_003325 (OMIM: 301830,314370) ubiquitin-like modifie (1058 aa) initn: 445 init1: 263 opt: 363 Z-score: 455.7 bits: 94.4 E(85289): 1.2e-18 Smith-Waterman score: 389; 29.2% identity (57.1% similar) in 373 aa overlap (9-319:45-414) 10 20 30 pF1KB5 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASR :. .. . . :.::. . : ::.:::..: NP_003 PDPKPGSNCSPAQSVLSEVPSVPTNGMAKNGSEADIDEGLYSRQLYVLGHEAMKRLQTSS 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB5 VLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLER ::. ::.:::.:::::.::.:::..:. :. . : ..:: .: ..:.::::.: : NP_003 VLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREEDIGKNRAEVSQPR 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB5 AQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDV .:: .: : . : . :.:.. :..: :: . ..: ..::. .::. ..:. NP_003 LAELNSYVPVTAYTGPLV---EDFLSGFQVVVLTNTPLEDQLRVGEFCHNRGIKLVVADT 140 150 160 170 180 190 160 170 180 190 200 pF1KB5 FGYHGYTFANLGEHEFVE----EKTKVAKVSQGVEDGP------DTKRAKLDSSETT--- : : : ..::. .. :. : ::. ..:.: : : ..:.. . NP_003 RGLFGQLFCDFGEEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFS 200 210 220 230 240 250 210 220 230 pF1KB5 ----MVKK--------KVV------FCP---------------VKEALEVDWSSEKAK-- ::. ::. .: :: .....: :. NP_003 EVQGMVELNGNQPMEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLVASLA 260 270 280 290 300 310 240 250 260 270 280 pF1KB5 ---------AALKRTTSDYFLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSL- : ..: .. .. .:.: .: ...:: : . :. .::. . .: NP_003 EPDFVVTDFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVALAQAVNARALP 320 330 340 350 360 370 290 300 310 320 330 pF1KB5 GISPDLLPEDFVR---YCFS-EMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKG ... . : ::..: : . ..::. : .::. :::..:: : NP_003 AVQQNNLDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPIMQWLYFDALEC 380 390 400 410 420 430 340 pF1KB5 NGIVECLGPK NP_003 LPEDKEVLTEDKCLQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIG 440 450 460 470 480 490 >>XP_016885269 (OMIM: 301830,314370) PREDICTED: ubiquiti (1058 aa) initn: 445 init1: 263 opt: 363 Z-score: 455.7 bits: 94.4 E(85289): 1.2e-18 Smith-Waterman score: 389; 29.2% identity (57.1% similar) in 373 aa overlap (9-319:45-414) 10 20 30 pF1KB5 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASR :. .. . . :.::. . : ::.:::..: XP_016 PDPKPGSNCSPAQSVLSEVPSVPTNGMAKNGSEADIDEGLYSRQLYVLGHEAMKRLQTSS 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB5 VLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLER ::. ::.:::.:::::.::.:::..:. :. . : ..:: .: ..:.::::.: : XP_016 VLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREEDIGKNRAEVSQPR 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB5 AQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDV .:: .: : . : . :.:.. :..: :: . ..: ..::. .::. ..:. XP_016 LAELNSYVPVTAYTGPLV---EDFLSGFQVVVLTNTPLEDQLRVGEFCHNRGIKLVVADT 140 150 160 170 180 190 160 170 180 190 200 pF1KB5 FGYHGYTFANLGEHEFVE----EKTKVAKVSQGVEDGP------DTKRAKLDSSETT--- : : : ..::. .. :. : ::. ..:.: : : ..:.. . XP_016 RGLFGQLFCDFGEEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFS 200 210 220 230 240 250 210 220 230 pF1KB5 ----MVKK--------KVV------FCP---------------VKEALEVDWSSEKAK-- ::. ::. .: :: .....: :. XP_016 EVQGMVELNGNQPMEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLVASLA 260 270 280 290 300 310 240 250 260 270 280 pF1KB5 ---------AALKRTTSDYFLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSL- : ..: .. .. .:.: .: ...:: : . :. .::. . .: XP_016 EPDFVVTDFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVALAQAVNARALP 320 330 340 350 360 370 290 300 310 320 330 pF1KB5 GISPDLLPEDFVR---YCFS-EMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKG ... . : ::..: : . ..::. : .::. :::..:: : XP_016 AVQQNNLDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPIMQWLYFDALEC 380 390 400 410 420 430 340 pF1KB5 NGIVECLGPK XP_016 LPEDKEVLTEDKCLQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIG 440 450 460 470 480 490 >>NP_695012 (OMIM: 301830,314370) ubiquitin-like modifie (1058 aa) initn: 445 init1: 263 opt: 363 Z-score: 455.7 bits: 94.4 E(85289): 1.2e-18 Smith-Waterman score: 389; 29.2% identity (57.1% similar) in 373 aa overlap (9-319:45-414) 10 20 30 pF1KB5 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASR :. .. . . :.::. . : ::.:::..: NP_695 PDPKPGSNCSPAQSVLSEVPSVPTNGMAKNGSEADIDEGLYSRQLYVLGHEAMKRLQTSS 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB5 VLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLER ::. ::.:::.:::::.::.:::..:. :. . : ..:: .: ..:.::::.: : NP_695 VLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREEDIGKNRAEVSQPR 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB5 AQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDV .:: .: : . : . :.:.. :..: :: . ..: ..::. .::. ..:. NP_695 LAELNSYVPVTAYTGPLV---EDFLSGFQVVVLTNTPLEDQLRVGEFCHNRGIKLVVADT 140 150 160 170 180 190 160 170 180 190 200 pF1KB5 FGYHGYTFANLGEHEFVE----EKTKVAKVSQGVEDGP------DTKRAKLDSSETT--- : : : ..::. .. :. : ::. ..:.: : : ..:.. . NP_695 RGLFGQLFCDFGEEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFS 200 210 220 230 240 250 210 220 230 pF1KB5 ----MVKK--------KVV------FCP---------------VKEALEVDWSSEKAK-- ::. ::. .: :: .....: :. NP_695 EVQGMVELNGNQPMEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLVASLA 260 270 280 290 300 310 240 250 260 270 280 pF1KB5 ---------AALKRTTSDYFLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSL- : ..: .. .. .:.: .: ...:: : . :. .::. . .: NP_695 EPDFVVTDFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVALAQAVNARALP 320 330 340 350 360 370 290 300 310 320 330 pF1KB5 GISPDLLPEDFVR---YCFS-EMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKG ... . : ::..: : . ..::. : .::. :::..:: : NP_695 AVQQNNLDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPIMQWLYFDALEC 380 390 400 410 420 430 340 pF1KB5 NGIVECLGPK NP_695 LPEDKEVLTEDKCLQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIG 440 450 460 470 480 490 346 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 17:13:39 2016 done: Thu Nov 3 17:13:40 2016 Total Scan time: 8.270 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]